Page last updated: 2024-10-29

avapro and Albuminuria

avapro has been researched along with Albuminuria in 74 studies

Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.

Albuminuria: The presence of albumin in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to assess the effects of irbesartan alone and combined with amlodipine, efonidipine, or trichlormethiazide on blood pressure (BP) and urinary albumin (UA) excretion in hypertensive patients with microalbuminuria (30≤UA/creatinine (Cr) ratio [UACR] <300 mg/g Cr) and upper-normal microalbuminuria (10≤UACR<30 mg/g Cr)."9.27Effect of amlodipine, efonidipine, and trichlormethiazide on home blood pressure and upper-normal microalbuminuria assessed by casual spot urine test in essential hypertensive patients. ( Asayama, K; Hanazawa, T; Hosaka, M; Imai, Y; Inoue, R; Obara, T; Ohkubo, T; Satoh, M; Watabe, D, 2018)
"In a multi-center, single-arm, prospective study, we investigated the efficacy and safety of the fixed irbesartan/hydrochlorothiazide combination in Chinese patients with moderate to severe hypertension."9.17Efficacy and safety of a fixed combination of irbesartan/hydrochlorothiazide in Chinese patients with moderate to severe hypertension. ( Dai, QY; Huang, QF; Li, Y; Ma, GS; Sheng, CS; Wang, JG, 2013)
" Therefore, we investigated the effects of irbesartan treatment on plasma levels of the AGEs N(ε)(1-carboxymethyl)lysine (CML) and N(ε)(1-carboxyethyl)lysine (CEL) in hypertensive patients with type 2 diabetes and microalbuminuria."9.15Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial. ( Engelen, L; Ferreira, I; Hovind, P; Parving, HH; Persson, F; Rossing, P; Schalkwijk, CG; Stehouwer, CD; Teerlink, T, 2011)
" After a 1-month washout period, 26 patients with type 2 diabetes, hypertension, and albuminuria (>100 mg/day) were randomly assigned to four 2-month treatment periods in random order with placebo, 300 mg aliskiren once daily, 300 mg irbesartan once daily, or the combination using identical doses."9.14Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria. ( Boomsma, F; Danser, AH; Frandsen, E; Juhl, T; Parving, HH; Persson, F; Reinhard, H; Rossing, P; Schalkwijk, C; Stehouwer, CD, 2009)
"The Aliskiren in the Evaluation of Proteinuria in Diabetes (AVOID) trial demonstrated that adding aliskiren, an oral direct renin inhibitor, at a dosage of 300 mg/d to the highest approved dosage of losartan and optimal antihypertensive therapy reduces albuminuria over 6 mo among patients with type 2 diabetes, hypertension, and albuminuria."7.75Cost-effectiveness of aliskiren in type 2 diabetes, hypertension, and albuminuria. ( Charney, A; Delea, TE; Lau, H; Munk, VC; Palmer, JL; Parving, HH; Sofrygin, O; Sullivan, SD; Sung, J, 2009)
"Diabetic spontaneously hypertensive rats developed albuminuria and had a reduction in both gene and protein expression of nephrin when compared with control rats."7.71Irbesartan normalises the deficiency in glomerular nephrin expression in a model of diabetes and hypertension. ( Allen, TJ; Boner, G; Bonnet, F; Cao, Z; Cooper, ME; Kawachi, H, 2001)
"We investigated, in individuals with type 2 diabetes, whether irbesartan lowered plasma levels of the dicarbonyls methylglyoxal, glyoxal, 3-deoxyglucosone and their derived advanced glycation end products (AGEs), and increased d-lactate, reflecting greater methylglyoxal flux."7.01Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study. ( Hanssen, NMJ; Hovind, P; Parving, HH; Persson, F; Piazza, M; Rossing, P; Schalkwijk, CG; Scheijen, JL; Stehouwer, CDA; van de Waarenburg, MPH; van Greevenbroek, MMJ, 2021)
"The aim of this study was to assess the effects of irbesartan alone and combined with amlodipine, efonidipine, or trichlormethiazide on blood pressure (BP) and urinary albumin (UA) excretion in hypertensive patients with microalbuminuria (30≤UA/creatinine (Cr) ratio [UACR] <300 mg/g Cr) and upper-normal microalbuminuria (10≤UACR<30 mg/g Cr)."5.27Effect of amlodipine, efonidipine, and trichlormethiazide on home blood pressure and upper-normal microalbuminuria assessed by casual spot urine test in essential hypertensive patients. ( Asayama, K; Hanazawa, T; Hosaka, M; Imai, Y; Inoue, R; Obara, T; Ohkubo, T; Satoh, M; Watabe, D, 2018)
"Changes in systolic blood pressure (SBP), albuminuria, potassium, haemoglobin, cholesterol and uric acid after 6 months of losartan treatment were assessed in the RENAAL database."5.20The renal protective effect of angiotensin receptor blockers depends on intra-individual response variation in multiple risk markers. ( de Zeeuw, D; Lambers Heerspink, HJ; Parving, HH; Rossing, P; Schievink, B, 2015)
"In a multi-center, single-arm, prospective study, we investigated the efficacy and safety of the fixed irbesartan/hydrochlorothiazide combination in Chinese patients with moderate to severe hypertension."5.17Efficacy and safety of a fixed combination of irbesartan/hydrochlorothiazide in Chinese patients with moderate to severe hypertension. ( Dai, QY; Huang, QF; Li, Y; Ma, GS; Sheng, CS; Wang, JG, 2013)
" Therefore, we investigated the effects of irbesartan treatment on plasma levels of the AGEs N(ε)(1-carboxymethyl)lysine (CML) and N(ε)(1-carboxyethyl)lysine (CEL) in hypertensive patients with type 2 diabetes and microalbuminuria."5.15Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial. ( Engelen, L; Ferreira, I; Hovind, P; Parving, HH; Persson, F; Rossing, P; Schalkwijk, CG; Stehouwer, CD; Teerlink, T, 2011)
" After a 1-month washout period, 26 patients with type 2 diabetes, hypertension, and albuminuria (>100 mg/day) were randomly assigned to four 2-month treatment periods in random order with placebo, 300 mg aliskiren once daily, 300 mg irbesartan once daily, or the combination using identical doses."5.14Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria. ( Boomsma, F; Danser, AH; Frandsen, E; Juhl, T; Parving, HH; Persson, F; Reinhard, H; Rossing, P; Schalkwijk, C; Stehouwer, CD, 2009)
" Inclusion criteria were type 2 diabetes, hypertension > 140/90 mmHg and current treatment with irbesartan or irbesartan/hydrochlorothiazide (HTCZ)."5.11[Observational study of blood pressure control and microalbuminuria in type 2 diabetics on irbesartan or irbesartan/HCTZ]. ( Krekler, M; Schmieder, RE, 2005)
" Risk factors for diabetic nephropathy are discussed, and include hyperglycemia, hypertension, angiotensin II, proteinuria, dyslipidemia, smoking, and anemia."4.82Outcome studies in diabetic nephropathy. ( Mohanram, A; Toto, RD, 2003)
"Currently, AIIAs such as losartan represent the only evidence-based treatment strategy for patients with type 2 DM and proteinuria."4.82Losartan and other angiotensin II antagonists for nephropathy in type 2 diabetes mellitus: a review of the clinical trial evidence. ( Ruilope, LM; Segura, J, 2003)
"The Aliskiren in the Evaluation of Proteinuria in Diabetes (AVOID) trial demonstrated that adding aliskiren, an oral direct renin inhibitor, at a dosage of 300 mg/d to the highest approved dosage of losartan and optimal antihypertensive therapy reduces albuminuria over 6 mo among patients with type 2 diabetes, hypertension, and albuminuria."3.75Cost-effectiveness of aliskiren in type 2 diabetes, hypertension, and albuminuria. ( Charney, A; Delea, TE; Lau, H; Munk, VC; Palmer, JL; Parving, HH; Sofrygin, O; Sullivan, SD; Sung, J, 2009)
"Diabetic spontaneously hypertensive rats developed albuminuria and had a reduction in both gene and protein expression of nephrin when compared with control rats."3.71Irbesartan normalises the deficiency in glomerular nephrin expression in a model of diabetes and hypertension. ( Allen, TJ; Boner, G; Bonnet, F; Cao, Z; Cooper, ME; Kawachi, H, 2001)
"We investigated, in individuals with type 2 diabetes, whether irbesartan lowered plasma levels of the dicarbonyls methylglyoxal, glyoxal, 3-deoxyglucosone and their derived advanced glycation end products (AGEs), and increased d-lactate, reflecting greater methylglyoxal flux."3.01Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study. ( Hanssen, NMJ; Hovind, P; Parving, HH; Persson, F; Piazza, M; Rossing, P; Schalkwijk, CG; Scheijen, JL; Stehouwer, CDA; van de Waarenburg, MPH; van Greevenbroek, MMJ, 2021)
" Patients were randomly divided into 4 groups: low-dose irbesartan (group A), high-dose irbesartan (group B), low-dose irbesartan combined with spironolactone (group C) and high-dose irbesartan combined with spironolactone (group D)."2.87Effects of Different Doses of Irbesartan Combined With Spironolactone on Urinary Albumin Excretion Rate in Elderly Patients With Early Type 2 Diabetic Nephropathy. ( Chen, X; Chen, Y; Li, Y; Liu, P; Wang, Y; Zhang, F, 2018)
"Treatment of patients with type 2 diabetes with Irbesartan decreased urinary excretion of MG-H1, G-H1 and 3-NT, which may result from decreased exposure to these AGEs."2.77Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria. ( Adaikalakoteswari, A; Parving, HH; Rabbani, N; Rossing, K; Rossing, P; Tarnow, L; Thornalley, PJ, 2012)
"The Irbesartan in Patients With Type 2 Diabetes and Microalbuminuria (IRMA 2) study was a 2-year multicenter randomized double-blind trial comparing irbesartan (150 and 300 mg once daily) with placebo."2.76Long-term effects of Irbesartan treatment and smoking on nucleic acid oxidation in patients with type 2 diabetes and microalbuminuria: an Irbesartan in patients with type 2 diabetes and Microalbuminuria (IRMA 2) substudy. ( Afzal, S; Andersen, JT; Broedbaek, K; Henriksen, T; Jimenez-Solem, E; Parving, HH; Persson, F; Petersen, M; Poulsen, HE; Rossing, P; Weimann, A, 2011)
"A total of 40 normotensive type 2 diabetes patients (mean age 55."2.73Short-term effects of irbesartan treatment on microalbuminuria in patients with normotensive type 2 diabetes. ( Cetinkalp, SS; Erdogan, MA; Karadeniz, MM; Ozgen, GA; Yilmaz, CO, 2008)
" The dosage was doubled if necessary."2.71Better renoprotective effect of angiotensin II antagonist compared to dihydropyridine calcium channel blocker in childhood. ( Bianchetti, MG; Edefonti, A; Fossali, E; Gartenmann, AC; Schmidtko, J; Simonetti, GD; von Vigier, RO, 2003)
"Ultrahigh dosing of irbesartan (900 mg once daily) is generally safe and offers additional renoprotection independent of changes in systemic blood pressure and GFR in comparison to the currently recommended dose of 300 mg."2.71Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria. ( Boomsma, F; Jensen, BR; Parving, HH; Rossing, K; Schjoedt, KJ, 2005)
"Patients with high blood pressure are often overweight or even obese."2.71[Arterial hypertension in obese patients. Rationale for a prospective medical care study in the family doctor's practice]. ( Bramlage, P; Kirch, W; Sharma, AM, 2004)
"Irbesartan treatment of patients with type 2 diabetes, hypertension, and microalbuminuria may lead to major improvements in long-term patient outcomes, with substantial cost savings as an added bonus to third party payers."2.42Health economics studies assessing irbesartan use in patients with hypertension, type 2 diabetes, and microalbuminuria. ( Palmer, AJ; Rodby, RA, 2004)
"Recently, the Reduction of Endpoints in NIDDM (non-insulin-dependent diabetes mellitus) with the Angiotensin II Antagonist Losartan (RENAAL) trial provided sufficient data to conclude that the blockade of the All AT1 receptor with losartan confers renoprotection in patients with DM-2 and nephropathy."2.41The role of angiotensin II antagonism in type 2 diabetes mellitus: a review of renoprotection studies. ( Ribeiro, AB; Zanella, MT, 2002)
"HKC was administered to the diabetic nephropathy rats at three different doses: high dose HKC (300mg/kg/d); middle dose HKC (175mg/kg/d); and low dose HKC (75mg/kg/d)."1.43Huangkui capsule, an extract from Abelmoschus manihot (L.) medic, improves diabetic nephropathy via activating peroxisome proliferator-activated receptor (PPAR)-α/γ and attenuating endoplasmic reticulum stress in rats. ( Ge, J; Miao, JJ; Sun, XY; Yu, JY, 2016)
"Data from patients with type 2 diabetes and microalbuminuria (n = 49) treated with irbesartan 300 mg/day were used for discovery."1.43Serum metabolites predict response to angiotensin II receptor blockers in patients with diabetes mellitus. ( Andersen, S; Dallmann, G; Heerspink, HJ; Heinzel, A; Mayer, B; Parving, HH; Pena, MJ; Rossing, K; Rossing, P, 2016)
"Captopril treatment reduced blood pressure (163+/-3 mmHg versus diabetic 201+/-3 mmHg), but not albumin excretion rate (43."1.31Additive hypotensive and anti-albuminuric effects of angiotensin-converting enzyme inhibition and angiotensin receptor antagonism in diabetic spontaneously hypertensive rats. ( Allen, TJ; Bonnet, F; Cao, Z; Cooper, ME; Davis, B, 2001)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.35)18.2507
2000's50 (67.57)29.6817
2010's20 (27.03)24.3611
2020's3 (4.05)2.80

Authors

AuthorsStudies
Zhao, J1
Tostivint, I1
Xu, L1
Huang, J1
Gambotti, L1
Boffa, JJ1
Yang, M1
Wang, L1
Sun, Z1
Chen, X2
Liou-Schischmanoff, A1
Baumelou, A1
Ma, T1
Lu, G1
Li, L1
Chen, D1
Piéroni, L1
Liu, B1
Qin, X1
He, W1
Wang, Y2
Gu, HF1
Sun, W1
Shin, J1
Kim, HS1
Min Kim, T1
Kim, H1
Lee, SH1
Hyoung Cho, J1
Lee, H1
Woo Yim, H1
Yoon, KH1
Piazza, M1
Hanssen, NMJ1
Persson, F7
Scheijen, JL1
van de Waarenburg, MPH1
van Greevenbroek, MMJ1
Rossing, P11
Hovind, P5
Stehouwer, CDA1
Parving, HH22
Schalkwijk, CG3
Hosaka, M1
Inoue, R1
Satoh, M2
Watabe, D1
Hanazawa, T1
Ohkubo, T1
Asayama, K1
Obara, T1
Imai, Y1
Zhao, XM1
Zhang, Y1
He, XH1
Chen, HD1
Wang, ZF1
Guo, J1
Wang, XM1
Gao, ZZ1
Wang, JP1
Liu, W1
Zhao, LH1
Tong, XL1
Chen, Y1
Liu, P1
Li, Y2
Zhang, F1
Huang, QF1
Sheng, CS1
Ma, GS1
Dai, QY1
Wang, JG1
Schievink, B1
de Zeeuw, D6
Lambers Heerspink, HJ3
Hayashi, K2
Sasamura, H1
Nakamura, M1
Sakamaki, Y1
Azegami, T1
Oguchi, H1
Tokuyama, H1
Wakino, S1
Itoh, H1
Felix Kröpelin, T1
Holtkamp, FA2
Packham, DK1
L Heerspink, HJ1
Ge, J1
Miao, JJ1
Sun, XY1
Yu, JY1
Pena, MJ1
Heinzel, A1
Dallmann, G1
Rossing, K6
Andersen, S8
Mayer, B1
Heerspink, HJ1
Stehouwer, CD4
Tarnow, L3
Cetinkalp, SS1
Karadeniz, MM1
Erdogan, MA1
Ozgen, GA1
Yilmaz, CO1
Reinhard, H1
Juhl, T1
Schalkwijk, C2
Danser, AH1
Boomsma, F2
Frandsen, E1
Delea, TE1
Sofrygin, O1
Palmer, JL1
Lau, H1
Munk, VC1
Sung, J1
Charney, A1
Sullivan, SD1
Whaley-Connell, A1
Nistala, R1
Habibi, J1
Hayden, MR1
Schneider, RI1
Johnson, MS1
Tilmon, R1
Rehmer, N1
Ferrario, CM1
Sowers, JR1
Kuwabara, A1
Tomita, N1
Sasaki, T1
Kashihara, N1
Mischak, H1
Zürbig, P1
Tebbe, U2
Bramlage, P6
Lüders, S2
Cuneo, A1
Sistig, P1
de Haan, F2
Schmieder, R1
Böhm, M2
Paar, WD3
Schrader, J2
Dai, HY1
Zheng, M1
Tang, RN1
Ni, J1
Ma, KL1
Li, Q1
Liu, BC1
Rabbani, N1
Adaikalakoteswari, A1
Thornalley, PJ1
Engelen, L1
Ferreira, I1
Teerlink, T1
de Graeff, PA1
Laverman, GD1
Berl, T1
Remuzzi, G1
Packham, D1
Lewis, JB1
Broedbaek, K1
Henriksen, T1
Weimann, A1
Petersen, M1
Andersen, JT1
Afzal, S1
Jimenez-Solem, E1
Poulsen, HE1
Nakamura, T1
Kataoka, K1
Tokutomi, Y1
Nako, H1
Toyama, K1
Dong, YF1
Koibuchi, N1
Yamamoto, E1
Yasuda, O1
Ogawa, H1
Kim-Mitsuyama, S1
Hellemons, ME1
Bakker, SJ1
Zanella, MT1
Ribeiro, AB1
Eguchi, K1
Kario, K1
Shimada, K1
Sasso, FC1
Carbonara, O1
Persico, M1
Iafusco, D1
Salvatore, T1
D'Ambrosio, R1
Torella, R1
Cozzolino, D1
Haneda, M1
Christensen, PK1
Hansen, HP1
Jacobsen, P2
Jensen, BR2
Mohanram, A1
Toto, RD1
Gartenmann, AC1
Fossali, E1
von Vigier, RO1
Simonetti, GD1
Schmidtko, J1
Edefonti, A1
Bianchetti, MG1
González-Albarrán, O1
Gómez, O1
Ruiz, E1
Vieitez, P1
García-Robles, R1
Bröchner-Mortensen, J2
Lehnert, H4
Pittrow, D2
Kirch, W3
Ruilope, LM1
Segura, J1
Kaiser, T1
Florack, C1
Sawicki, PT1
Schunkert, H1
Palmer, AJ5
Rodby, RA3
Llewelyn, DE1
Garcia-Puig, J1
de Alvaro, F2
Velasco, O1
Honorato, J1
Calvo, C1
Parrondo, I1
Annemans, L2
Roze, S4
Lapuerta, P2
Chen, R2
Gabriel, S2
Carita, P2
Chiarelli, F1
Di Marzio, D1
Santilli, F1
Mohn, A1
Blasetti, A1
Cipollone, F1
Mezzetti, A1
Verrotti, A1
Schjoedt, KJ1
Schmieder, RE3
Krekler, M2
Sharma, AM1
Valentine, WJ3
Ray, JA3
Frei, A1
Burnier, M1
Hess, B1
Spinas, GA1
Brändle, M1
Tschöpe, C1
Tschöpe, R1
Unger, T1
Tucker, DM1
Laville, M1
Muszbek, N1
Wong, DW1
Oudit, GY1
Reich, H1
Kassiri, Z1
Zhou, J1
Liu, QC1
Backx, PH1
Penninger, JM1
Herzenberg, AM1
Scholey, JW1
Bakris, GL1
Ruilope, L1
Locatelli, F1
Ptaszynska, A1
Pieske, B1
de Champlain, J1
Weber, MA1
Raz, I1
Tuttle, KR1
Flack, JM1
Thoenes, M2
Bramlage, CP1
O'Donnell, MP1
Crary, GS1
Oda, H1
Kasiske, BL1
Powell, JR1
Keane, WF1
Cao, Z2
Bonnet, F2
Davis, B1
Allen, TJ2
Cooper, ME2
Kawachi, H1
Boner, G1
Gomis, R2
Arner, P2
Bloomgarden, ZT1
Brøchner-Mortensen, J1
Hansen, BV1
Studney, D1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-blind, Parallel-controlled, Multi-center Clinical Trial of HuangKui Capsule to Treat Diabetic Kidney Disease[NCT03016832]Early Phase 1414 participants (Anticipated)Interventional2017-01-31Recruiting
The Irbesartan in Patients With Type 2 Diabetes and Microalbuminuria (IRMA 2)[NCT00317915]Phase 30 participants InterventionalCompleted
A Randomized, Double-Blind, Parallel-Group, Cross-Over, 4-Period, 4 Treatment, Within-Subject Placebo-Controlled Study to Assess the Reno-Protective Effect of Renin Inhibition With Aliskiren as an Alternative to Irbesartan in Type 2 Patients With Incipien[NCT00464880]Phase 1/Phase 224 participants Interventional2005-09-30Completed
Optimal Dose of Irbesartan for Renoprotection in Type 2 Diabetic Patients With Persistent Microalbuminuria[NCT00320879]Phase 452 participants Interventional2003-09-30Completed
Pre-existing Microalbuminuria Predicting Contrast-induced Acute Kidney Injury (CIAKI) Following Coronary Angiography (CAG)[NCT02808845]800 participants (Anticipated)Observational2016-12-31Not yet recruiting
Irbesartan Versus Placebo in Combination With Standard Cardiovascular Protection ACE-I Therapy With Ramipril for the Treatment of Albuminuria in Hypertensive Subjects at Elevated Cardiovascular Risk[NCT00095290]Phase 4400 participants Interventional2004-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for avapro and Albuminuria

ArticleYear
Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials.
    European heart journal, 2011, Volume: 32, Issue:12

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure;

2011
The role of angiotensin II antagonism in type 2 diabetes mellitus: a review of renoprotection studies.
    Clinical therapeutics, 2002, Volume: 24, Issue:7

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperte

2002
[What is a good marker for better antihypertensive therapy in diabetic patients when coexisting with hypertension].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biomarkers;

2002
[Diabetic nephropathy].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 10

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomarkers;

2002
Outcome studies in diabetic nephropathy.
    Seminars in nephrology, 2003, Volume: 23, Issue:3

    Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme

2003
Losartan and other angiotensin II antagonists for nephropathy in type 2 diabetes mellitus: a review of the clinical trial evidence.
    Clinical therapeutics, 2003, Volume: 25, Issue:12

    Topics: Albuminuria; Amlodipine; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Clinical Trial

2003
Health economics studies assessing irbesartan use in patients with hypertension, type 2 diabetes, and microalbuminuria.
    Kidney international. Supplement, 2004, Issue:92

    Topics: Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Cost Savings; Diabetes Mellitus, Type 2; H

2004
Maximising antihypertensive effects of angiotensin II receptor blockers with thiazide diuretic combination therapy: focus on irbesartan/hydrochlorothiazide.
    International journal of clinical practice, 2007, Volume: 61, Issue:12

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; D

2007
Angiotensin blockade in type 2 diabetes: what the new evidence tells us about renal and cardiac complications.
    The Canadian journal of cardiology, 2002, Volume: 18 Suppl A

    Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors;

2002

Trials

31 trials available for avapro and Albuminuria

ArticleYear
Efficacy of Combined Abelmoschus manihot and Irbesartan for Reduction of Albuminuria in Patients With Type 2 Diabetes and Diabetic Kidney Disease: A Multicenter Randomized Double-Blind Parallel Controlled Clinical Trial.
    Diabetes care, 2022, 07-07, Volume: 45, Issue:7

    Topics: Abelmoschus; Albuminuria; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dou

2022
Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study.
    Diabetic medicine : a journal of the British Diabetic Association, 2021, Volume: 38, Issue:9

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Chromatography, Liquid; Deoxygluco

2021
Effect of amlodipine, efonidipine, and trichlormethiazide on home blood pressure and upper-normal microalbuminuria assessed by casual spot urine test in essential hypertensive patients.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2018, Volume: 40, Issue:5

    Topics: Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pr

2018
Chinese herbal medicine Shenzhuo Formula treatment in patients with macroalbuminuria secondary to diabetic kidney disease: study protocol for a randomized controlled trial.
    Trials, 2018, Mar-27, Volume: 19, Issue:1

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biomarkers; China; Creatinine; Diabetic Nephro

2018
Effects of Different Doses of Irbesartan Combined With Spironolactone on Urinary Albumin Excretion Rate in Elderly Patients With Early Type 2 Diabetic Nephropathy.
    The American journal of the medical sciences, 2018, Volume: 355, Issue:5

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Diabetes Mellitus, Type 2; Diabetic Neph

2018
Efficacy and safety of a fixed combination of irbesartan/hydrochlorothiazide in Chinese patients with moderate to severe hypertension.
    Drugs in R&D, 2013, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Aged; Albuminuria; Antihypertensive Agents; Asian People; Biphenyl Compounds; Blo

2013
The renal protective effect of angiotensin receptor blockers depends on intra-individual response variation in multiple risk markers.
    British journal of clinical pharmacology, 2015, Volume: 80, Issue:4

    Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Biomarkers; Biphenyl Compounds; Blood Pr

2015
Endothelial dysfunction and inflammation predict development of diabetic nephropathy in the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria (IRMA 2) study.
    Scandinavian journal of clinical and laboratory investigation, 2008, Volume: 68, Issue:8

    Topics: Adult; Aged; Albuminuria; Biomarkers; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephro

2008
Short-term effects of irbesartan treatment on microalbuminuria in patients with normotensive type 2 diabetes.
    Saudi medical journal, 2008, Volume: 29, Issue:10

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Diabetes M

2008
Renal effects of aliskiren compared with and in combination with irbesartan in patients with type 2 diabetes, hypertension, and albuminuria.
    Diabetes care, 2009, Volume: 32, Issue:10

    Topics: Aged; Albuminuria; Amides; Antihypertensive Agents; Biphenyl Compounds; Diabetes Mellitus, Type 2; D

2009
Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria.
    Amino acids, 2012, Volume: 42, Issue:5

    Topics: Albuminuria; Amino Acids; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bendrofl

2012
Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:11

    Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Biomarkers; Biphenyl Compounds; Diabetes

2011
Long-term effects of Irbesartan treatment and smoking on nucleic acid oxidation in patients with type 2 diabetes and microalbuminuria: an Irbesartan in patients with type 2 diabetes and Microalbuminuria (IRMA 2) substudy.
    Diabetes care, 2011, Volume: 34, Issue:5

    Topics: Aged; Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Diabetes Mellitus, Type 2; Double-Bl

2011
initial angiotensin receptor blockade-induced decrease in albuminuria is associated with long-term renal outcome in type 2 diabetic patients with microalbuminuria: a post hoc analysis of the IRMA-2 trial.
    Diabetes care, 2011, Volume: 34, Issue:9

    Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Diab

2011
Irbesartan reduces the albumin excretion rate in microalbuminuric type 2 diabetic patients independently of hypertension: a randomized double-blind placebo-controlled crossover study.
    Diabetes care, 2002, Volume: 25, Issue:11

    Topics: Adult; Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Cross-Over Studies; Diabetes Mellit

2002
Comparative effects of Irbesartan on ambulatory and office blood pressure: a substudy of ambulatory blood pressure from the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria study.
    Diabetes care, 2003, Volume: 26, Issue:3

    Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood Pressur

2003
Dual blockade of the renin-angiotensin system versus maximal recommended dose of ACE inhibition in diabetic nephropathy.
    Kidney international, 2003, Volume: 63, Issue:5

    Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Comp

2003
Better renoprotective effect of angiotensin II antagonist compared to dihydropyridine calcium channel blocker in childhood.
    Kidney international, 2003, Volume: 64, Issue:4

    Topics: Adolescent; Albuminuria; Amlodipine; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Bl

2003
Kidney function during and after withdrawal of long-term irbesartan treatment in patients with type 2 diabetes and microalbuminuria.
    Diabetes care, 2003, Volume: 26, Issue:12

    Topics: Albuminuria; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes M

2003
[IRMA-pRAcs: irbesartan in the treatment of microalbuminuria and proteinuria in patients with type 2 diabetes and hypertension-prospective observational study involving 38,016 patients in the general practice setting].
    MMW Fortschritte der Medizin, 2003, Oct-09, Volume: 145 Suppl 3

    Topics: Adolescent; Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agen

2003
How different urinary albumin excretion rates can predict progression to nephropathy and the effect of treatment in hypertensive diabetics.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2004, Volume: 5, Issue:3

    Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Diabetic Angiopathies; Diabet

2004
Microalbuminuria in hypertensive patients: evaluation of one-year treatment with irbesartan.
    Kidney international. Supplement, 2005, Issue:93

    Topics: Albuminuria; Algorithms; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Female; Follow

2005
Effects of irbesartan on intracellular antioxidant enzyme expression and activity in adolescents and young adults with early diabetic angiopathy.
    Diabetes care, 2005, Volume: 28, Issue:7

    Topics: Adolescent; Adult; Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Case-Co

2005
Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria.
    Kidney international, 2005, Volume: 68, Issue:3

    Topics: Aged; Albuminuria; Aldosterone; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood P

2005
[Observational study of blood pressure control and microalbuminuria in type 2 diabetics on irbesartan or irbesartan/HCTZ].
    MMW Fortschritte der Medizin, 2005, Oct-06, Volume: 147 Suppl 3

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compou

2005
[Arterial hypertension in obese patients. Rationale for a prospective medical care study in the family doctor's practice].
    MMW Fortschritte der Medizin, 2004, Aug-05, Volume: 146 Suppl 2

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; C

2004
Irbesartan treatment reduces biomarkers of inflammatory activity in patients with type 2 diabetes and microalbuminuria: an IRMA 2 substudy.
    Diabetes, 2006, Volume: 55, Issue:12

    Topics: Aged; Albuminuria; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Diabetes Mellitus, Type

2006
Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: results of the IMPROVE trial.
    Kidney international, 2007, Volume: 72, Issue:7

    Topics: Aged; Aged, 80 and over; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convertin

2007
Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: results of the IMPROVE trial.
    Kidney international, 2007, Volume: 72, Issue:7

    Topics: Aged; Aged, 80 and over; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convertin

2007
Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: results of the IMPROVE trial.
    Kidney international, 2007, Volume: 72, Issue:7

    Topics: Aged; Aged, 80 and over; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convertin

2007
Treatment of microalbuminuria in hypertensive subjects with elevated cardiovascular risk: results of the IMPROVE trial.
    Kidney international, 2007, Volume: 72, Issue:7

    Topics: Aged; Aged, 80 and over; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Convertin

2007
The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes.
    The New England journal of medicine, 2001, Sep-20, Volume: 345, Issue:12

    Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compou

2001
[Effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes].
    Ugeskrift for laeger, 2001, Oct-01, Volume: 163, Issue:40

    Topics: Adult; Aged; Albuminuria; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Cardiovascula

2001
Dual blockade of the renin-angiotensin system in type 1 patients with diabetic nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2002, Volume: 17, Issue:6

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds;

2002

Other Studies

34 other studies available for avapro and Albuminuria

ArticleYear
The short-term effects of angiotensin II receptor blockers on albuminuria and renal function in Korean patients.
    Basic & clinical pharmacology & toxicology, 2020, Volume: 126, Issue:5

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazo

2020
Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria.
    Kidney international, 2015, Volume: 88, Issue:4

    Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphe

2015
Individual long-term albuminuria exposure during angiotensin receptor blocker therapy is the optimal predictor for renal outcome.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2016, Volume: 31, Issue:9

    Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Biphenyl Compounds; Diabetes Mellitus, T

2016
Huangkui capsule, an extract from Abelmoschus manihot (L.) medic, improves diabetic nephropathy via activating peroxisome proliferator-activated receptor (PPAR)-α/γ and attenuating endoplasmic reticulum stress in rats.
    Journal of ethnopharmacology, 2016, Aug-02, Volume: 189

    Topics: Abelmoschus; Administration, Oral; Albuminuria; Animals; Biphenyl Compounds; Capsules; Diabetes Mell

2016
Serum metabolites predict response to angiotensin II receptor blockers in patients with diabetes mellitus.
    Journal of translational medicine, 2016, 07-05, Volume: 14, Issue:1

    Topics: Adult; Albuminuria; Angiotensin Receptor Antagonists; Biphenyl Compounds; Diabetes Mellitus, Type 2;

2016
Cost-effectiveness of aliskiren in type 2 diabetes, hypertension, and albuminuria.
    Journal of the American Society of Nephrology : JASN, 2009, Volume: 20, Issue:10

    Topics: Albuminuria; Amides; Biphenyl Compounds; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Diabetic

2009
Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 rat.
    American journal of physiology. Renal physiology, 2010, Volume: 298, Issue:3

    Topics: Albuminuria; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Comp

2010
Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats.
    Diabetologia, 2010, Volume: 53, Issue:9

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blotting, Western

2010
Urinary proteome analysis enables assessment of renoprotective treatment in type 2 diabetic patients with microalbuminuria.
    BMC nephrology, 2010, Nov-01, Volume: 11

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Diabetes Mellitus, Type 2;

2010
Follow-up of cardiovascular risk markers in hypertensive patients treated with irbesartan: results of the i-SEARCH Plus Registry.
    Journal of clinical hypertension (Greenwich, Conn.), 2010, Volume: 12, Issue:12

    Topics: Aged; Albuminuria; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; C-Reactive Protein; Card

2010
Effects of angiotensin receptor blocker on phenotypic alterations of podocytes in early diabetic nephropathy.
    The American journal of the medical sciences, 2011, Volume: 341, Issue:3

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers;

2011
Novel mechanism of salt-induced glomerular injury: critical role of eNOS and angiotensin II.
    Journal of hypertension, 2011, Volume: 29, Issue:8

    Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Bipheny

2011
[Dangerous deficits in management of hypertensive diabetic patients. A kidney check is far from standard procedure].
    MMW Fortschritte der Medizin, 2003, Apr-24, Volume: 145, Issue:17

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Diabetes

2003
Role of systolic blood pressureon the progression of kidney damage in an experimental model of type 2 diabetes mellitus, obesity, and hypertension (Zucker rats).
    American journal of hypertension, 2003, Volume: 16, Issue:11 Pt 1

    Topics: Albuminuria; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus

2003
[Prospective treatment study of irbesartan. Diabetic kidneys regain function].
    MMW Fortschritte der Medizin, 2003, Oct-09, Volume: 145, Issue:41

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; C

2003
[Diabetic patients have to be tested regularly for microalbuminuria. Almost every second one has already kidney damage].
    MMW Fortschritte der Medizin, 2004, Jan-29, Volume: 146, Issue:5

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; C

2004
Kidney function during and after withdrawal of long-term irbesartan treatment in patients with type 2 diabetes and microalbuminuria: response to Andersen, Brochner-Mortensen, and Parving.
    Diabetes care, 2004, Volume: 27, Issue:6

    Topics: Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephro

2004
[A threat to cardiovascular risk patients. "Activated renin-angiotensin system promotes end organ damage" (interview by Waldtraud Paukstadt)].
    MMW Fortschritte der Medizin, 2004, Jun-03, Volume: 146, Issue:23

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Cardiovascular Diseases;

2004
[Test for microalbuminuria. Life saving for hypertensive and diabetic patients].
    MMW Fortschritte der Medizin, 2004, Aug-05, Volume: 146, Issue:31-32

    Topics: Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Coronary Artery Disease; Diabetic Nephropa

2004
Irbesartan is projected to be cost and life saving in a Spanish setting for treatment of patients with type 2 diabetes, hypertension, and microalbuminuria.
    Kidney international. Supplement, 2005, Issue:93

    Topics: Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cost Savings; Diabetes Mel

2005
[Observational study of blood pressure control and microalbuminuria in type 2 diabetics on Irbesartan or Irbesartan/HCTZ].
    MMW Fortschritte der Medizin, 2005, Aug-04, Volume: 147, Issue:31-32

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; C

2005
Health economic implications of irbesartan plus conventional antihypertensive medications versus conventional blood pressure control alone in patients with type 2 diabetes, hypertension, and renal disease in Switzerland.
    Swiss medical weekly, 2006, 05-27, Volume: 136, Issue:21-22

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; C

2006
[Microalbuminuria in patients with hypertension and cardiovascular comorbidity, REAL observational study of treatment with Irbesartan/HCTZ].
    MMW Fortschritte der Medizin, 2006, Jun-22, Volume: 148, Issue:25

    Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compo

2006
A French cost-consequence analysis of the renoprotective benefits of irbesartan in patients with type 2 diabetes and hypertension.
    Current medical research and opinion, 2006, Volume: 22, Issue:11

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cost-Benefit Analysis; Dia

2006
Health economic implications of irbesartan treatment versus standard blood pressure control in patients with type 2 diabetes, hypertension and renal disease: a Hungarian analysis.
    The European journal of health economics : HEPAC : health economics in prevention and care, 2007, Volume: 8, Issue:2

    Topics: Albuminuria; Antihypertensive Agents; Biphenyl Compounds; Cohort Studies; Comorbidity; Costs and Cos

2007
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury.
    The American journal of pathology, 2007, Volume: 171, Issue:2

    Topics: Actins; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Anima

2007
Albuminuria reduction: the holy grail for kidney protection.
    Kidney international, 2007, Volume: 72, Issue:7

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biom

2007
[Long-term follow-up of cardiovascular risk markers in patients with hypertension. Rationale, design, and baseline characteristics of the i-Search Plus Registry].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Oct-15, Volume: 102, Issue:10

    Topics: Adult; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl

2007
[Albuminuria: an indicator of cardiovascular risk].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Oct-15, Volume: 102, Issue:10

    Topics: Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Anticholesteremic Agents; Antihypertensi

2007
Irbesartan lowers blood pressure and ameliorates renal injury in experimental non-insulin-dependent diabetes mellitus.
    Kidney international. Supplement, 1997, Volume: 63

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Co

1997
Additive hypotensive and anti-albuminuric effects of angiotensin-converting enzyme inhibition and angiotensin receptor antagonism in diabetic spontaneously hypertensive rats.
    Clinical science (London, England : 1979), 2001, Volume: 100, Issue:6

    Topics: Albuminuria; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

2001
Irbesartan normalises the deficiency in glomerular nephrin expression in a model of diabetes and hypertension.
    Diabetologia, 2001, Volume: 44, Issue:7

    Topics: Albuminuria; Analysis of Variance; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Di

2001
Angiotensin II receptor blockers and nephropathy trials.
    Diabetes care, 2001, Volume: 24, Issue:10

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds;

2001
[Diabetic patient with hypertension takes A-I I blocker. Less likely dialysis].
    MMW Fortschritte der Medizin, 2002, Feb-21, Volume: 144, Issue:8

    Topics: Albuminuria; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents;

2002