avapro has been researched along with Aging in 3 studies
Irbesartan: A spiro compound, biphenyl and tetrazole derivative that acts as an angiotensin II type 1 receptor antagonist. It is used in the management of HYPERTENSION, and in the treatment of kidney disease.
irbesartan : A biphenylyltetrazole that is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No statistically significant gender effects were observed in peak plasma concentration (Cmax), area under the curve (AUC), and terminal elimination half-life (t1/2) of irbesartan." | 2.69 | The effects of age and gender on the pharmacokinetics of irbesartan. ( Greene, DS; Shyu, WC; Smith, RA; Vachharajani, NN, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yabumoto, C | 1 |
| Akazawa, H | 1 |
| Yamamoto, R | 1 |
| Yano, M | 1 |
| Kudo-Sakamoto, Y | 1 |
| Sumida, T | 1 |
| Kamo, T | 1 |
| Yagi, H | 1 |
| Shimizu, Y | 1 |
| Saga-Kamo, A | 1 |
| Naito, AT | 1 |
| Oka, T | 1 |
| Lee, JK | 1 |
| Suzuki, J | 1 |
| Sakata, Y | 1 |
| Uejima, E | 1 |
| Komuro, I | 1 |
| Oudit, GY | 1 |
| Kassiri, Z | 1 |
| Patel, MP | 1 |
| Chappell, M | 1 |
| Butany, J | 1 |
| Backx, PH | 1 |
| Tsushima, RG | 1 |
| Scholey, JW | 1 |
| Khokha, R | 1 |
| Penninger, JM | 1 |
| Vachharajani, NN | 1 |
| Shyu, WC | 1 |
| Smith, RA | 1 |
| Greene, DS | 1 |
1 trial available for avapro and Aging
| Article | Year |
|---|---|
The effects of age and gender on the pharmacokinetics of irbesartan.
Topics: Adolescent; Adult; Aged; Aging; Angiotensin Receptor Antagonists; Antihypertensive Agents; Area Unde | 1998 |
2 other studies available for avapro and Aging
| Article | Year |
|---|---|
Angiotensin II receptor blockade promotes repair of skeletal muscle through down-regulation of aging-promoting C1q expression.
Topics: Administration, Topical; Aging; Angiotensin II Type 1 Receptor Blockers; Animals; Axin Protein; Biph | 2015 |
Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.
Topics: Adaptor Proteins, Signal Transducing; Aging; Angiotensin II; Angiotensin-Converting Enzyme 2; Animal | 2007 |