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aurintricarboxylic acid and Disease Models, Animal

aurintricarboxylic acid has been researched along with Disease Models, Animal in 11 studies

Aurintricarboxylic Acid: A dye which inhibits protein biosynthesis at the initial stages. The ammonium salt (aluminon) is a reagent for the colorimetric estimation of aluminum in water, foods, and tissues.
aurintricarboxylic acid : A member of the class of quinomethanes that is 3-methylidene-6-oxocyclohexa-1,4-diene-1-carboxylic acid in which the methylidene hydrogens are replaced by 4-carboxy-3-hydroxyphenyl groups. The trisodium salt is the biological stain 'chrome violet CG' while the triammonium salt is 'aluminon'.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Aurintricarboxylic Acid (ATA) is a small molecule inhibitor of MAC."5.39Aurintricarboxylic acid inhibits complement activation, membrane attack complex, and choroidal neovascularization in a model of macular degeneration. ( Cashman, SM; Kumar-Singh, R; Lipo, E, 2013)
" Furthermore, we show that treatment with the PMCA4 inhibitor aurintricarboxylic acid (ATA) inhibits and reverses cardiac hypertrophy induced by pressure overload in mice."3.83The plasma membrane calcium ATPase 4 signalling in cardiac fibroblasts mediates cardiomyocyte hypertrophy. ( Abou-Leisa, R; Baudoin-Stanley, F; Cartwright, EJ; Maqsood, A; Mohamed, TMA; Neyses, L; Oceandy, D; Prehar, S; Stafford, N; Wang, X; Zi, M, 2016)
"Aurintricarboxylic Acid (ATA) is a small molecule inhibitor of MAC."1.39Aurintricarboxylic acid inhibits complement activation, membrane attack complex, and choroidal neovascularization in a model of macular degeneration. ( Cashman, SM; Kumar-Singh, R; Lipo, E, 2013)
"Multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE), are autoimmune diseases characterized by the immune-mediated demyelination and neurodegeneration of the CNS."1.39Aurintricarboxylic acid ameliorates experimental autoimmune encephalomyelitis by blocking chemokine-mediated pathogenic cell migration and infiltration. ( Chai, H; Wei, W; Xie, X; Zhang, F, 2013)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Lipo, E1
Cashman, SM1
Kumar-Singh, R1
Zhao, T1
Gao, J1
Van, J1
To, E1
Wang, A1
Cao, S1
Cui, JZ1
Guo, JP1
Lee, M1
McGeer, PL1
Matsubara, JA1
Mohamed, TMA1
Abou-Leisa, R1
Stafford, N1
Maqsood, A1
Zi, M1
Prehar, S1
Baudoin-Stanley, F1
Wang, X1
Neyses, L1
Cartwright, EJ1
Oceandy, D1
Zhang, F1
Wei, W1
Chai, H1
Xie, X1
Clemetson, KJ1
Clemetson, JM1
Bernat, A1
Lale, A1
Herbert, JM1
Golino, P2
Ragni, M2
Cirillo, P2
Pascucci, I1
Ezekowitz, MD1
Pawashe, A1
Scognamiglio, A1
Pace, L1
Guarino, A1
Chiariello, M2
Ambrosio, G1
Esposito, N1
Willerson, JT1
Rothlein, R1
Petrucci, L1
Condorelli, M1
Buja, LM1
Elsliger, MA1
Thériault, GR1
Gauthier, D1

Reviews

1 review available for aurintricarboxylic acid and Disease Models, Animal

ArticleYear
Platelet GPIb complex as a target for anti-thrombotic drug development.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:3

    Topics: Animals; Aurintricarboxylic Acid; Blood Platelets; Disease Models, Animal; Drug Design; Fibrinolytic

2008

Other Studies

10 other studies available for aurintricarboxylic acid and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Aurintricarboxylic acid inhibits complement activation, membrane attack complex, and choroidal neovascularization in a model of macular degeneration.
    Investigative ophthalmology & visual science, 2013, Oct-29, Volume: 54, Issue:10

    Topics: Adult; Animals; Apoptosis; Aurintricarboxylic Acid; Cells, Cultured; Choroidal Neovascularization; C

2013
Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye.
    Journal of neuroinflammation, 2015, Jun-24, Volume: 12

    Topics: Aging; Amyloid beta-Peptides; Animals; Aurintricarboxylic Acid; Carrier Proteins; Choroid; Complemen

2015
The plasma membrane calcium ATPase 4 signalling in cardiac fibroblasts mediates cardiomyocyte hypertrophy.
    Nature communications, 2016, Mar-29, Volume: 7

    Topics: Animals; Animals, Newborn; Aorta; Aurintricarboxylic Acid; Calcium-Transporting ATPases; Cardiomegal

2016
Aurintricarboxylic acid ameliorates experimental autoimmune encephalomyelitis by blocking chemokine-mediated pathogenic cell migration and infiltration.
    Journal of immunology (Baltimore, Md. : 1950), 2013, Feb-01, Volume: 190, Issue:3

    Topics: Adoptive Transfer; Amino Acid Sequence; Animals; Apoptosis; Aurintricarboxylic Acid; CD4-Positive T-

2013
Aurin tricarboxylic acid inhibits experimental venous thrombosis.
    Thrombosis research, 1994, Jun-15, Volume: 74, Issue:6

    Topics: Agglutination; Animals; Arteriovenous Shunt, Surgical; Aurintricarboxylic Acid; Bleeding Time; Blood

1994
Aurintricarboxylic acid reduces platelet deposition in stenosed and endothelially injured rabbit carotid arteries more effectively than other antiplatelet interventions.
    Thrombosis and haemostasis, 1995, Volume: 74, Issue:3

    Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Aurintricarboxylic Acid; Blood Flow Velocity;

1995
Inhibition of leucocyte and platelet adhesion reduces neointimal hyperplasia after arterial injury.
    Thrombosis and haemostasis, 1997, Volume: 77, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Aurintricarboxylic Acid; Carotid Stenosis; CD11 Antigens; CD18 Anti

1997
In vitro localization of the protein synthesis defect associated with experimental phenylketonuria.
    Neurochemical research, 1989, Volume: 14, Issue:1

    Topics: Animals; Aurintricarboxylic Acid; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; E

1989