aureothin and HIV-Infections

aureothin has been researched along with HIV-Infections* in 1 studies

Other Studies

1 other study(ies) available for aureothin and HIV-Infections

Article	Year
Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin. Scientific reports, 2020, Jan-28, Volume: 10, Issue:1 Overcoming the global health threat of HIV infection requires continuous pipelines of novel drug candidates. We identified the γ-pyrone polyketides Aureothin/Neoaureothin as potent hits by anti-HIV screening of an extensive natural compound collection. Total synthesis of a structurally diverse group of Aureothin-derivatives successfully identified a lead compound (#7) superior to Aureothin that combines strong anti-HIV activity (IC Topics: Antiviral Agents; Chromones; Drug Design; Drug Synergism; HIV; HIV Infections; Humans; Microbial Sensitivity Tests; Molecular Structure; Polyketides; Primary Cell Culture; Virus Replication	2020

Article

Year

Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin.

Scientific reports, 2020, Jan-28, Volume: 10, Issue:1

Overcoming the global health threat of HIV infection requires continuous pipelines of novel drug candidates. We identified the γ-pyrone polyketides Aureothin/Neoaureothin as potent hits by anti-HIV screening of an extensive natural compound collection. Total synthesis of a structurally diverse group of Aureothin-derivatives successfully identified a lead compound (#7) superior to Aureothin that combines strong anti-HIV activity (IC

Topics: Antiviral Agents; Chromones; Drug Design; Drug Synergism; HIV; HIV Infections; Humans; Microbial Sensitivity Tests; Molecular Structure; Polyketides; Primary Cell Culture; Virus Replication

2020