aurapten and Colitis--Ulcerative

aurapten has been researched along with Colitis--Ulcerative* in 1 studies

Other Studies

1 other study(ies) available for aurapten and Colitis--Ulcerative

Article	Year
Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice. Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:12 Previously we reported that auraptene was a potent suppressant for matrix metalloproteinase (MMP)-7 expression in HT-29 human colon cancer cells. In the present study, we examined the effects of auraptene on MMP-2, -7, and -9 expression in colonic mucosa from dextran sulfate sodium (DSS)-induced ulcerative colitis mice. Auraptene remarkably suppressed the DSS-induced gelatinolytic activity of MMP-7 as well as the expression of MMP-2 and -9, suggesting that it might be useful in anti-metastatic therapies via the targeting of MMPs. Topics: Animals; Colitis, Ulcerative; Coumarins; Dextran Sulfate; Female; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred ICR	2006

Article

Year

Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice.

Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:12

Previously we reported that auraptene was a potent suppressant for matrix metalloproteinase (MMP)-7 expression in HT-29 human colon cancer cells. In the present study, we examined the effects of auraptene on MMP-2, -7, and -9 expression in colonic mucosa from dextran sulfate sodium (DSS)-induced ulcerative colitis mice. Auraptene remarkably suppressed the DSS-induced gelatinolytic activity of MMP-7 as well as the expression of MMP-2 and -9, suggesting that it might be useful in anti-metastatic therapies via the targeting of MMPs.

Topics: Animals; Colitis, Ulcerative; Coumarins; Dextran Sulfate; Female; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred ICR

2006