aucubin has been researched along with Disease Models, Animal in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (66.67) | 24.3611 |
| 2020's | 6 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Hu, M; Li, Y; Liu, X; Song, M; Wang, D; Yang, A; Zhang, Y | 1 |
| Jung, WK; Kim, J; Kim, YH; Park, SB; Yu, HY | 1 |
| Bai, X; Liu, P; Rao, X; Song, S; Wang, Y; Yang, P | 1 |
| Ai, Q; Dong, Y; Jiang, W; Ma, H; Shi, X; Shi, Y; Wang, Z; Yang, X; Zhang, Y | 1 |
| Chen, PS; Jiang, Y; Wang, BW; Wang, SN; Yao, ZL; Yu, B | 1 |
| Jung, E; Jung, WK; Kim, HR; Kim, J; Park, SB | 1 |
| Deng, CL; Gao, YY; Hang, CH; Li, W; Liu, GJ; Lu, Y; Tao, T; Wang, H; Wang, J; Wu, LY; Xu, WD; Zhang, XS; Zhou, XM; Zhou, Y; Zhuang, Z | 1 |
| Hu, K; Huang, WH; Li, J; Li, XH; Li, Y; Ouyang, DS; Wang, J; Xiao, B; Xiao, J; Zeng, XC; Zhou, J | 1 |
| Chen, L; Coffie, JW; Fang, Z; Gao, X; Geng, X; Li, C; Qiu, L; Song, M; Wang, H; Yang, Y; You, X; Zhang, L | 1 |
| Duan, JX; Guan, CX; Guan, XX; Li, P; Liu, T; Liu, YP; Mei, WX; Ouyang, DS; Sun, GY; Wan, L; Zhong, WJ; Zhou, Y | 1 |
| Chen, Z; He, J; Li, Y; Lv, L; Sun, W; Wang, Z; Wen, X; Yang, Y; Yin, B; Zhang, Y; Zhao, Y | 1 |
| Bai, F; Cheng, XN; Fang, LY; Hu, HZ; Qiu, YL; Sun, DQ | 1 |
| Chen, X; Cui, C; Jia, XB; Shen, YQ; Sun, MF; Xu, YD; Xu, ZH; Yang, XS; Zhang, PH; Zhou, ZL; Zhu, YL | 1 |
| Duan, MX; Liao, HH; Liu, C; Meng, YY; Tang, QZ; Wu, QQ; Xiao, Y; Yang, Z; Yuan, Y | 1 |
| Jung, E; Kang, WS; Kim, J | 1 |
| Chen, L; Chen, S; Hu, K; Huang, Q; Huang, X; Li, C; Ouyang, DS; Wang, X; Zeng, G; Zeng, X; Zhou, L; Zong, W | 1 |
| Chen, YS; Chuang, ST; Hsu, CH; Lin, FH; Liu, HC; Sun, YJ; Young, IC | 1 |
18 other study(ies) available for aucubin and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Aucubin slows the development of osteoporosis by inhibiting osteoclast differentiation via the nuclear factor erythroid 2-related factor 2-mediated antioxidation pathway.
Topics: Animals; Antioxidants; Cell Differentiation; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Iridoid Glucosides; Male; Mice; Mice, Inbred C57BL; NF-E2 Transcription Factor, p45 Subunit; Osteoclasts; Osteoporosis; RAW 264.7 Cells | 2021 |
Effect of Aucubin-Containing Eye Drops on Tear Hyposecretion and Lacrimal Gland Damage Induced by Urban Particulate Matter in Rats.
Topics: Animals; Disease Models, Animal; Dry Eye Syndromes; Iridoid Glucosides; Lacrimal Apparatus; Male; Ophthalmic Solutions; Particulate Matter; Rats; Rats, Sprague-Dawley | 2022 |
Aucubin improves chronic unpredictable mild stress-induced depressive behavior in mice via the GR/NF-κB/NLRP3 axis.
Topics: Animals; Depression; Depressive Disorder; Disease Models, Animal; Hippocampus; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Receptors, Glucocorticoid; Stress, Psychological | 2023 |
Aucubin inhibits hepatic stellate cell activation through stimulating Nrf2/Smad7 axis.
Topics: Animals; Collagen Type I; Disease Models, Animal; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Mice; NF-E2-Related Factor 2; Transforming Growth Factor beta | 2023 |
Aucubin Protects Chondrocytes Against IL-1β-Induced Apoptosis In Vitro And Inhibits Osteoarthritis In Mice Model.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Chondrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Interleukin-1beta; Iridoid Glucosides; Male; Mice; Mice, Inbred C57BL; Osteoarthritis; Protective Agents; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2019 |
Aucubin, An Active Ingredient in
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA Damage; Iridoid Glucosides; Magnoliopsida; Male; Methylnitrosourea; Mice, Inbred C57BL; Oxidative Stress; Photoreceptor Cells, Vertebrate; Plant Extracts; Retina; Retinal Degeneration | 2019 |
Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury.
Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Inflammation; Iridoid Glucosides; Mice; Mice, Inbred C57BL; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction | 2020 |
The Protective Effect of Aucubin from Eucommia ulmoides Against Status Epilepticus by Inducing Autophagy and Inhibiting Necroptosis.
Topics: Animals; Autophagy; Disease Models, Animal; Eucommiaceae; Hippocampus; Humans; Iridoid Glucosides; Male; Necrosis; Neuroprotective Agents; Phytotherapy; Rats, Sprague-Dawley; Status Epilepticus | 2017 |
Aucubin promotes angiogenesis via estrogen receptor beta in a mouse model of hindlimb ischemia.
Topics: Angiogenesis Inducing Agents; Animals; Disease Models, Animal; Estrogen Receptor beta; Female; Femoral Artery; Gene Expression Regulation; Hindlimb; Iridoid Glucosides; Ischemia; Ligation; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Ovariectomy; Phytoestrogens; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-akt; Recovery of Function; Signal Transduction; Vascular Endothelial Growth Factor A | 2017 |
Aucubin Alleviates Bleomycin-Induced Pulmonary Fibrosis in a Mouse Model.
Topics: Animals; Bleomycin; Cell Differentiation; Disease Models, Animal; Fibroblasts; Inflammation; Iridoid Glucosides; Mice; Pulmonary Fibrosis | 2017 |
Gastroprotective effect of aucubin against ethanol-induced gastric mucosal injury in mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Eucommiaceae; Gastric Mucosa; Glutathione; HSP70 Heat-Shock Proteins; Interleukin-6; Iridoid Glucosides; Male; Malondialdehyde; Mice; Oxidative Stress; Peroxidase; Seeds; Stomach Ulcer; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Aucubin protects against lipopolysaccharide-induced acute pulmonary injury through regulating Nrf2 and AMPK pathways.
Topics: Acute Lung Injury; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Cytoprotection; Disease Models, Animal; Humans; Inflammation Mediators; Iridoid Glucosides; Lipopolysaccharides; Lung; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; RAW 264.7 Cells; Signal Transduction; THP-1 Cells; Time Factors | 2018 |
Aucubin alleviates glial cell activation and preserves dopaminergic neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian mice.
Topics: Animals; Astrocytes; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Iridoid Glucosides; Male; Mice, Inbred C57BL; Microglia; Motor Activity; Neuroprotective Agents; Parkinson Disease; Parkinsonian Disorders; Substantia Nigra; Tyrosine 3-Monooxygenase | 2018 |
Aucubin Protects against Myocardial Infarction-Induced Cardiac Remodeling via nNOS/NO-Regulated Oxidative Stress.
Topics: Animals; Cell Line; Disease Models, Animal; Echocardiography; Hemodynamics; Immunohistochemistry; In Situ Nick-End Labeling; Iridoid Glucosides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Nitrogen Oxides; Oxidative Stress; Rats; Reactive Oxygen Species; Thioredoxins; Ventricular Remodeling | 2018 |
Topics: Animals; Apoptosis; Cell Survival; Chromatography, High Pressure Liquid; Cytokines; Desiccation; Disease Models, Animal; Epithelial Cells; Epithelium, Corneal; Gene Expression; Inflammation Mediators; Iridoid Glucosides; Magnoliopsida; Mice; Molecular Structure; Plant Extracts; Protective Agents; Rats; Tears; Xerophthalmia | 2018 |
Aucubin Alleviates Seizures Activity in Li-Pilocarpine-Induced Epileptic Mice: Involvement of Inhibition of Neuroinflammation and Regulation of Neurotransmission.
Topics: Animals; Astrocytes; Disease Models, Animal; Epilepsy; Hippocampus; Iridoid Glucosides; Lithium; Male; Mice; Microglia; Pilocarpine; Seizures; Synaptic Transmission | 2019 |
Protective effects of aucubin on osteoarthritic chondrocyte model induced by hydrogen peroxide and mechanical stimulus.
Topics: Aggrecans; Animals; Apoptosis; Caspase 3; Cell Proliferation; Chondrocytes; Collagen Type II; Disease Models, Animal; Gene Expression; Hydrogen Peroxide; In Vitro Techniques; Interleukin-6; Iridoid Glucosides; Matrix Metalloproteinase 13; Osteoarthritis; Physical Stimulation; Reactive Oxygen Species; Swine | 2017 |