Page last updated: 2024-09-05

atropine and Alzheimer Disease

atropine has been researched along with Alzheimer Disease in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's5 (25.00)18.2507
2000's7 (35.00)29.6817
2010's4 (20.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Gureviciene, I; Jin, N; Tanila, H; Ziyatdinova, S1
Alcantara-Gonzalez, D; Chartampila, E; Criscuolo, C; Scharfman, HE1
Fraser, P; Lambe, EK; McLaurin, J; Proulx, É1
Agbedahunsi, JM; Ahmed, T; Choudhary, MI; Ghayur, MN; Gilani, AH; Houghton, PJ; Khalid, A; Nawaz, SA1
Felberbaum, M; Hoffman, RS; Manini, AF; Mercurio-Zappala, M; Russell-Haders, AL1
Hachisu, M; Hori, K; Hosoyamada, M; Kataoka, A; Kimura, M; Konishi, K; Shibasaki, T; Tominaga, I; Uchida, H; Watanabe, K1
Bateman, GA; Ebrahimi, H; Jones, AL; Murray, SR; Schofield, PW1
Hicks, DA; Makova, NZ; Nalivaeva, NN; Turner, AJ1
Albuquerque, EX; Lopes, C; Njar, V; Pereira, EF; Purushottamachar, P; Schwarcz, R; Wu, HQ1
Burn, DJ; Lees, AJ; Perry, EK; Piggott, MA; Warren, NM1
Nordberg, A; Svensson, AL; Zhang, X1
Albrecht, C; Bloss, HG; Feuerstein, TJ; Jackisch, R1
Chang, KC; Chen, CL; Chiu, TH; Yang, YR1
Koch, HJ; Raschka, C; Szecsey, A1
Ferree, AW; Isacson, O; Seo, H1
Growdon, JH; Nitsch, RM; Slack, BE; Wurtman, RJ1
Caraceni, T; Cocchi, D; Lamperti, E; Müller, EE; Parati, EA1
Inzelberg, R; Korczyn, AD; Shapira, T1
Drukarch, B; Kits, KS; Lodder, JC; Stoof, JC; Van der Meer, EG1
Crawley, JN; Mastropaolo, J; Nadi, NS; Ostrowski, NL1

Other Studies

20 other study(ies) available for atropine and Alzheimer Disease

ArticleYear
Response of spike-wave discharges in aged APP/PS1 Alzheimer model mice to antiepileptic, metabolic and cholinergic drugs.
    Scientific reports, 2020, 07-16, Volume: 10, Issue:1

    Topics: 3-Hydroxybutyric Acid; Action Potentials; Alzheimer Disease; Animals; Anticonvulsants; Atropine; Disease Models, Animal; Donepezil; Drug Administration Schedule; Electroencephalography; Epilepsy; Ethosuximide; GABA Antagonists; Humans; Injections, Intraperitoneal; Lactic Acid; Levetiracetam; Male; Mice; Mice, Transgenic; Nootropic Agents; Organophosphorus Compounds; Parasympatholytics; Plaque, Amyloid; Pyruvic Acid; Video Recording

2020
Early changes in synaptic and intrinsic properties of dentate gyrus granule cells in a mouse model of Alzheimer's disease neuropathology and atypical effects of the cholinergic antagonist atropine.
    Neurobiology of disease, 2021, Volume: 152

    Topics: Alzheimer Disease; Animals; Atropine; Dentate Gyrus; Disease Models, Animal; Excitatory Postsynaptic Potentials; Humans; Mice; Mice, Transgenic; Muscarinic Antagonists; Neurons; Synaptic Transmission

2021
Impaired Cholinergic Excitation of Prefrontal Attention Circuitry in the TgCRND8 Model of Alzheimer's Disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Sep-16, Volume: 35, Issue:37

    Topics: Acetylcholine; Action Potentials; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Apamin; Atropine; Attention; Calcium Signaling; Cholinergic Neurons; Disease Models, Animal; Female; Genotype; Ion Channel Gating; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Small-Conductance Calcium-Activated Potassium Channels; Synaptic Transmission

2015
Muscarinic, Ca(++) antagonist and specific butyrylcholinesterase inhibitory activity of dried ginger extract might explain its use in dementia.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:10

    Topics: Acetylcholine; Alzheimer Disease; Animals; Atropine; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Fatty Alcohols; Gastric Fundus; In Vitro Techniques; Molecular Structure; Muscarinic Agonists; Parasympatholytics; Physostigmine; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome; Verapamil; Zingiber officinale

2008
Use of pralidoxime without atropine in rivastigmine (carbamate) toxicity.
    Human & experimental toxicology, 2009, Volume: 28, Issue:9

    Topics: Administration, Cutaneous; Aged, 80 and over; Alzheimer Disease; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Overdose; Female; Humans; Phenylcarbamates; Pralidoxime Compounds; Rivastigmine; Treatment Outcome

2009
Adverse effects of anticholinergic activity on cognitive functions in Alzheimer's disease.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2010, Volume: 10, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atropine; Cholinergic Antagonists; Cognition Disorders; Female; Humans; Male; Mental Status Schedule; Psychotropic Drugs; Receptors, Cholinergic

2010
An olfactory 'stress test' may detect preclinical Alzheimer's disease.
    BMC neurology, 2012, May-02, Volume: 12

    Topics: Administration, Intranasal; Aged; Aged, 80 and over; Alzheimer Disease; Atropine; Early Diagnosis; Female; Humans; Male; Olfactory Bulb; Reproducibility of Results; Sensitivity and Specificity; Smell

2012
Characterisation of acetylcholinesterase release from neuronal cells.
    Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Atropine; Butyrylcholinesterase; Carbachol; Cell Line; Cell Membrane; GPI-Linked Proteins; Humans; Metalloproteases; Mice; Muscarine; Muscarinic Agonists; Nerve Tissue Proteins; Neurons

2013
Competitive antagonism between the nicotinic allosteric potentiating ligand galantamine and kynurenic acid at alpha7* nicotinic receptors.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:1

    Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Atropine; Cells, Cultured; Choline; Corpus Striatum; Dopamine; Galantamine; Kynurenic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic

2007
Intact coupling of M1 receptors and preserved M2 and M4 receptors in the cortex in progressive supranuclear palsy: contrast with other dementias.
    Journal of chemical neuroanatomy, 2008, Volume: 35, Issue:3

    Topics: Alzheimer Disease; Atropine; Autoradiography; Carbachol; Cerebral Cortex; Dementia; Humans; Lewy Body Disease; Muscarinic Agonists; Muscarinic Antagonists; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Retrospective Studies; Supranuclear Palsy, Progressive; Tissue Banks

2008
Biphasic effect of tacrine on acetylcholine release in rat brain via M1 and M2 receptors.
    Brain research, 1996, Jul-08, Volume: 726, Issue:1-2

    Topics: Acetylcholine; Alzheimer Disease; Analysis of Variance; Animals; Atropine; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Synaptosomes; Tacrine

1996
Evaluation of autoreceptor-mediated control of [(3)H]acetylcholine release in rat and human neocortex.
    Experimental brain research, 1999, Volume: 128, Issue:3

    Topics: Acetylcholine; Aged; Alzheimer Disease; Animals; Atropine; Carrier Proteins; Electric Stimulation; Female; Humans; Male; Membrane Transport Proteins; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Neocortex; Oxotremorine; Rats; Synaptic Transmission; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins

1999
Arecoline excites rat locus coeruleus neurons by activating the M2-muscarinic receptor.
    The Chinese journal of physiology, 2000, Mar-31, Volume: 43, Issue:1

    Topics: Alzheimer Disease; Animals; Arecoline; Atropine; Cholinergic Agonists; Diamines; Hexamethonium; Locus Coeruleus; Male; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic

2000
Severe bradyarrhythmia in a patient with Alzheimer's disease and a patient with cerebral ischaemia, both induced by acute distension of the bladder.
    International journal of clinical practice, 2001, Volume: 55, Issue:5

    Topics: Acute Disease; Aged; Aged, 80 and over; Alzheimer Disease; Atropine; Bradycardia; Brain Ischemia; Electrocardiography; Female; Humans; Tomography, X-Ray Computed; Urinary Bladder Diseases; Urinary Catheterization; Urinary Retention

2001
Cortico-hippocampal APP and NGF levels are dynamically altered by cholinergic muscarinic antagonist or M1 agonist treatment in normal mice.
    The European journal of neuroscience, 2002, Volume: 15, Issue:3

    Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Atropine; Cerebral Cortex; Cholinergic Fibers; Down-Regulation; Drug Interactions; Female; Hippocampus; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Nerve Growth Factor; Parasympathomimetics; Receptor, Muscarinic M1; Receptors, Muscarinic; Succinimides; Synaptic Transmission

2002
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors.
    Science (New York, N.Y.), 1992, Oct-09, Volume: 258, Issue:5080

    Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Protein Precursor; Atropine; Blotting, Western; Brain Chemistry; Carbachol; Cell Line; Embryo, Mammalian; Humans; Kidney; Kinetics; Protein Kinase C; Receptors, Muscarinic; Staurosporine; Transfection

1992
Growth hormone responses to cholinergically active drugs in patients with dementia of the Alzheimer type.
    Alzheimer disease and associated disorders, 1992,Spring, Volume: 6, Issue:1

    Topics: Aged; Alzheimer Disease; Atropine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Male; Middle Aged; Pyridostigmine Bromide; Radioimmunoassay; Time Factors

1992
Effects of atropine on learning and memory functions in dementia.
    Clinical neuropharmacology, 1990, Volume: 13, Issue:3

    Topics: Alzheimer Disease; Atropine; Dementia; Dementia, Multi-Infarct; Humans; Learning; Memory; Parkinson Disease

1990
9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K+ current.
    European journal of pharmacology, 1987, Sep-02, Volume: 141, Issue:1

    Topics: Alzheimer Disease; Aminoacridines; Animals; Atropine; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Electrophysiology; In Vitro Techniques; Ion Channels; Lymnaea; Male; Oxotremorine; Physostigmine; Rats; Rats, Inbred Strains; Tacrine

1987
Galanin antagonizes acetylcholine on a memory task in basal forebrain-lesioned rats.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:24

    Topics: Acetylcholine; Alzheimer Disease; Animals; Atropine; Brain; Galanin; Injections, Intraventricular; Male; Mecamylamine; Memory; Peptides; Rats; Rats, Inbred Strains

1988