atrial-natriuretic-factor and Poultry-Diseases

Experiments were conducted to determine if hypotensive responses to chicken cardiac hypotensive extract (CHE) or synthetic rat atrial natriuretic peptide (ANP) are affected by dietary sodium. The CHE was significantly more hypotensive in chickens fed high-sodium diets than in chickens fed low-sodium diets. Atrial natriuretic peptide was equally hypotensive in both groups. Experiments were also conducted to determine whether CHE inhibits the hypertensive response to arginine vasotocin (AVT), the avian antidiuretic hormone. The acute hypertensive response to AVT was inhibited by CHE; and CHE reversed the AVT-induced increase in the baseline mean arterial blood pressure.

Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Chickens; Female; Hypotension; Kidney; Myocardium; Poultry Diseases; Random Allocation; Sodium; Sodium, Dietary; Tissue Extracts; Vasotocin