atrial-natriuretic-factor and Out-of-Hospital-Cardiac-Arrest

atrial-natriuretic-factor has been researched along with Out-of-Hospital-Cardiac-Arrest* in 2 studies

Trials

1 trial(s) available for atrial-natriuretic-factor and Out-of-Hospital-Cardiac-Arrest

Article	Year
MR-proANP and NT-proBNP During Targeted Temperature Management Following Out-of-Hospital Cardiac Arrest: A Therapeutic hypothermia and temperature management, 2022, Volume: 12, Issue:2 We aimed to evaluate the effect of prolonged targeted temperature management (TTM) in patients with out-of-hospital cardiac arrest (OHCA) on the levels of midregional pro-atrial natriuretic peptide (MR-proANP) and N-terminal pro b-type natriuretic peptide (NT-proBNP) and assess their potential as prognostic biomarkers. A preplanned Topics: Atrial Natriuretic Factor; Biomarkers; Humans; Hypothermia, Induced; Natriuretic Peptide, Brain; Out-of-Hospital Cardiac Arrest; Peptide Fragments	2022

Article

Year

MR-proANP and NT-proBNP During Targeted Temperature Management Following Out-of-Hospital Cardiac Arrest: A

Therapeutic hypothermia and temperature management, 2022, Volume: 12, Issue:2

We aimed to evaluate the effect of prolonged targeted temperature management (TTM) in patients with out-of-hospital cardiac arrest (OHCA) on the levels of midregional pro-atrial natriuretic peptide (MR-proANP) and N-terminal pro b-type natriuretic peptide (NT-proBNP) and assess their potential as prognostic biomarkers. A preplanned

Topics: Atrial Natriuretic Factor; Biomarkers; Humans; Hypothermia, Induced; Natriuretic Peptide, Brain; Out-of-Hospital Cardiac Arrest; Peptide Fragments

2022

Other Studies

1 other study(ies) available for atrial-natriuretic-factor and Out-of-Hospital-Cardiac-Arrest

Article	Year
The Combination of Biomarkers for Prognostication of Long-Term Outcome in Patients Treated with Mild Hypothermia After Out-of-Hospital Cardiac Arrest-A Pilot Study. Therapeutic hypothermia and temperature management, 2016, Volume: 6, Issue:2 To explore if the brain biomarker neuron-specific enolase (NSE) in combination with a biomarker for stress; CT-proAVP (copeptin), oxidation; peroxiredoxin 4 (Prx4), inflammation; procalcitonin (PCT), or with biomarkers from the heart; midregional proatrial natriuretic peptide (MR-proANP), or troponin T (TnT) can improve the prognostic accuracy of long-term outcome after out-of-hospital cardiac arrest (OHCA). Serum samples from cardiac arrest patients, treated at 33°C for 24 hours, were collected serially at 12, 24, and 48 hours after cardiac arrest. The concentration of the investigated biomarkers was measured using stored samples, and long-term outcome was evaluated by the cerebral performance category (CPC) at 6 months. Poor outcome was defined as CPC 3-5. Sixty-two patients with OHCA of presumed cardiac cause were included. NSE had best prognostic accuracy for poor outcome at 48 hours with a receiver operating characteristic area under curve (AUC) of 0.94 (95% confidence interval [CI] 0.87-1). The combination of NSE with TnT, both at 48 hours, increased the AUC to 0.98 (95% CI 0.95-1, likelihood ratio [LR] test p-value 0.07, net reclassification index [NRI] <0.001); NSE and MR-proANP, both at 12 hours, yielded an AUC of 0.91 (95% CI 0.80-1, LR test p-value 0.0014, NRI p-value 0.003); NSE at 48 hours with MR-proANP at 12 hours yielded an AUC of 0.97 (95% CI 0.92-1, LR test p-value 0.055, NRI p-value 0.04). This pilot study suggests that a combination of biomarkers with NSE could be beneficial for improving early prognostication of long-term outcome following OHCA. Topics: Adult; Aged; Atrial Natriuretic Factor; Biomarkers; Female; Glycopeptides; Humans; Hypothermia, Induced; Long Term Adverse Effects; Male; Middle Aged; Out-of-Hospital Cardiac Arrest; Peroxiredoxins; Phosphopyruvate Hydratase; Predictive Value of Tests; Prognosis; Reproducibility of Results; Troponin T	2016

Article

Year

The Combination of Biomarkers for Prognostication of Long-Term Outcome in Patients Treated with Mild Hypothermia After Out-of-Hospital Cardiac Arrest-A Pilot Study.

Therapeutic hypothermia and temperature management, 2016, Volume: 6, Issue:2

To explore if the brain biomarker neuron-specific enolase (NSE) in combination with a biomarker for stress; CT-proAVP (copeptin), oxidation; peroxiredoxin 4 (Prx4), inflammation; procalcitonin (PCT), or with biomarkers from the heart; midregional proatrial natriuretic peptide (MR-proANP), or troponin T (TnT) can improve the prognostic accuracy of long-term outcome after out-of-hospital cardiac arrest (OHCA). Serum samples from cardiac arrest patients, treated at 33°C for 24 hours, were collected serially at 12, 24, and 48 hours after cardiac arrest. The concentration of the investigated biomarkers was measured using stored samples, and long-term outcome was evaluated by the cerebral performance category (CPC) at 6 months. Poor outcome was defined as CPC 3-5. Sixty-two patients with OHCA of presumed cardiac cause were included. NSE had best prognostic accuracy for poor outcome at 48 hours with a receiver operating characteristic area under curve (AUC) of 0.94 (95% confidence interval [CI] 0.87-1). The combination of NSE with TnT, both at 48 hours, increased the AUC to 0.98 (95% CI 0.95-1, likelihood ratio [LR] test p-value 0.07, net reclassification index [NRI] <0.001); NSE and MR-proANP, both at 12 hours, yielded an AUC of 0.91 (95% CI 0.80-1, LR test p-value 0.0014, NRI p-value 0.003); NSE at 48 hours with MR-proANP at 12 hours yielded an AUC of 0.97 (95% CI 0.92-1, LR test p-value 0.055, NRI p-value 0.04). This pilot study suggests that a combination of biomarkers with NSE could be beneficial for improving early prognostication of long-term outcome following OHCA.

Topics: Adult; Aged; Atrial Natriuretic Factor; Biomarkers; Female; Glycopeptides; Humans; Hypothermia, Induced; Long Term Adverse Effects; Male; Middle Aged; Out-of-Hospital Cardiac Arrest; Peroxiredoxins; Phosphopyruvate Hydratase; Predictive Value of Tests; Prognosis; Reproducibility of Results; Troponin T

2016