atrial-natriuretic-factor and Adrenal-Cortex-Diseases

atrial-natriuretic-factor has been researched along with Adrenal-Cortex-Diseases* in 2 studies

Other Studies

2 other study(ies) available for atrial-natriuretic-factor and Adrenal-Cortex-Diseases

Article	Year
Effect of glucocorticoid substitution on the secretion of atrial natriuretic peptide (ANP) in patients with adrenocortical insufficiency. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1991, Volume: 23, Issue:6 Topics: Adrenal Cortex Diseases; Adult; Aged; Atrial Natriuretic Factor; Dexamethasone; Female; Glucocorticoids; Hematocrit; Humans; Male; Middle Aged	1991
Plasma concentration of atrial natriuretic hormone during endogenous glucocorticoid hypercorticism. Hormone research, 1990, Volume: 34, Issue:5-6 In vitro studies have shown that glucocorticoids may increase atrial natriuretic-hormone (ANH) synthesis and/or release. This action of glucocorticoids has also been suggested in vivo in patients with Cushing's syndrome. However, in this circumstance, plasma AH elevation might be due to humoral disturbances associated with cortisol overproduction. We studied 16 patients with endogenous hypercorticism and 11 of them after successful treatment. Plasma levels of ANH, plasma renin activity (PRA), aldosterone, desoxycorticosterone (DOC), angiotensin II (AII), cortisol, osmolarity, sodium and potassium, urinary free cortisol (UFC), and blood pressure were measured. Before treatment the mean plasma ANH concentration in patients with Cushing's syndrome was significantly higher than in controls (11.3 +/- 2.6 vs. 4.9 +/- 2.3 pmol/l; p less than 0.001). ANH was correlated with cortisol and UFC (r = 0.715, r = 0.700; p less than 0.05). There was no significant correlation between plasma ANH, PRA, aldosterone, DOC, AII, osmolarity, sodium or blood pressure. After recovery, ANH concentration decreased in all patients and was not different from that of normal subjects (4.9 +/- 2.3 vs. 4.3 +/- 2.6 pmol/l). These results suggest that in Cushing's syndrome, ANH secretion is mainly dependent on the severity of hypercortisolism and independent of the other associated disturbances that we studied. Topics: ACTH Syndrome, Ectopic; Adenoma; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adult; Angiotensin II; Atrial Natriuretic Factor; Cushing Syndrome; Desoxycorticosterone; Humans	1990

Article

Year

Effect of glucocorticoid substitution on the secretion of atrial natriuretic peptide (ANP) in patients with adrenocortical insufficiency.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1991, Volume: 23, Issue:6

Topics: Adrenal Cortex Diseases; Adult; Aged; Atrial Natriuretic Factor; Dexamethasone; Female; Glucocorticoids; Hematocrit; Humans; Male; Middle Aged

1991

Plasma concentration of atrial natriuretic hormone during endogenous glucocorticoid hypercorticism.

Hormone research, 1990, Volume: 34, Issue:5-6

In vitro studies have shown that glucocorticoids may increase atrial natriuretic-hormone (ANH) synthesis and/or release. This action of glucocorticoids has also been suggested in vivo in patients with Cushing's syndrome. However, in this circumstance, plasma AH elevation might be due to humoral disturbances associated with cortisol overproduction. We studied 16 patients with endogenous hypercorticism and 11 of them after successful treatment. Plasma levels of ANH, plasma renin activity (PRA), aldosterone, desoxycorticosterone (DOC), angiotensin II (AII), cortisol, osmolarity, sodium and potassium, urinary free cortisol (UFC), and blood pressure were measured. Before treatment the mean plasma ANH concentration in patients with Cushing's syndrome was significantly higher than in controls (11.3 +/- 2.6 vs. 4.9 +/- 2.3 pmol/l; p less than 0.001). ANH was correlated with cortisol and UFC (r = 0.715, r = 0.700; p less than 0.05). There was no significant correlation between plasma ANH, PRA, aldosterone, DOC, AII, osmolarity, sodium or blood pressure. After recovery, ANH concentration decreased in all patients and was not different from that of normal subjects (4.9 +/- 2.3 vs. 4.3 +/- 2.6 pmol/l). These results suggest that in Cushing's syndrome, ANH secretion is mainly dependent on the severity of hypercortisolism and independent of the other associated disturbances that we studied.

Topics: ACTH Syndrome, Ectopic; Adenoma; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Adrenocortical Hyperfunction; Adult; Angiotensin II; Atrial Natriuretic Factor; Cushing Syndrome; Desoxycorticosterone; Humans

1990