Page last updated: 2024-10-23

atrazine and Pregnancy

atrazine has been researched along with Pregnancy in 67 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Using data from the National Birth Defects Prevention Study, a population-based case-control study, we considered the role of maternal exposure to atrazine, a widely used herbicide and potential endocrine disruptor, via drinking water in the etiology of 2nd and 3rd degree hypospadias."7.83Hypospadias and maternal exposure to atrazine via drinking water in the National Birth Defects Prevention study. ( Band, LE; Emch, M; Langlois, P; Luben, TJ; Meyer, RE; Mosley, B; Olshan, AF; Weyer, P; Winston, JJ, 2016)
"To establish an easily reproducible animal model of hypospadias and to test whether Atrazine can induce hypospadias in animal experiment."7.74[The establishment of hypospadias rat model and embryoteratogenic test of Atrazine]. ( Gao, H; Li, SK; Li, YQ; Shou, KR; Wang, YS; Wu, YG; Xin, ZC, 2007)
"Atrazine (ATR) is a commonly used agricultural herbicide that has been the subject of epidemiologic studies assessing its relation to reproductive health problems."6.50Atrazine and pregnancy outcomes: a systematic review of epidemiologic evidence. ( DeSesso, JM; Goodman, M; Mandel, JS; Scialli, AR, 2014)
"Atrazine has been demonstrated with a variety of endocrine disrupting activities and reproductive toxicities."5.62Prenatal exposure to atrazine induces cryptorchidism and hypospadias in F1 male mouse offspring. ( Chen, D; Lawless, J; Sinn, A; Tan, H; Wang, S; Wu, G; Zheng, Z, 2021)
"Atrazine (ATR) is an herbicide that has been shown to have adverse reproductive effects including alterations in levels of pituitary hormones such as prolactin (prl) and luteinizing hormone (LH) in female LE rats when administered at doses of 200 mg/kg/day for 1 and 3 days."5.31Effect of atrazine on implantation and early pregnancy in 4 strains of rats. ( Cooper, RL; Cummings, AM; Rhodes, BE, 2000)
"Using data from the National Birth Defects Prevention Study, a population-based case-control study, we considered the role of maternal exposure to atrazine, a widely used herbicide and potential endocrine disruptor, via drinking water in the etiology of 2nd and 3rd degree hypospadias."3.83Hypospadias and maternal exposure to atrazine via drinking water in the National Birth Defects Prevention study. ( Band, LE; Emch, M; Langlois, P; Luben, TJ; Meyer, RE; Mosley, B; Olshan, AF; Weyer, P; Winston, JJ, 2016)
"Even if we took neighborhood deprivation into account, we could not show a significant relationship between exposure to atrazine metabolites, or mixtures, in drinking-water during the second trimester of pregnancy and PTB."3.83Association between Exposure to Endocrine Disruptors in Drinking Water and Preterm Birth, Taking Neighborhood Deprivation into Account: A Historic Cohort Study. ( Albouy-Llaty, M; Carles, C; Dupuis, A; Limousi, F; Migeot, V; Rabouan, S, 2016)
" The main objective of our research was to investigate whether area deprivation may modify the association between drinking water exposure to a mixture of atrazine metabolites and nitrates during the second trimester of pregnancy and prevalence of small for gestational age (SGA) neonates."3.80Does area deprivation modify the association between exposure to a nitrate and low-dose atrazine metabolite mixture in drinking water and small for gestational age? A historic cohort study. ( Albouy-Llaty, M; Carles, C; Dupuis, A; Limousi, F; Migeot, V; Rabouan, S, 2014)
"To assess the relationship between estimated residential maternal exposure to atrazine during pregnancy and the risk for choanal atresia or stenosis in offspring."3.79Maternal residential atrazine exposure and risk for choanal atresia and stenosis in offspring. ( Agopian, AJ; Cai, Y; Canfield, MA; Langlois, PH; Lupo, PJ, 2013)
" Exposure to drinking-water atrazine metabolites/nitrate mixture was divided into 6 classes according to the presence or absence of atrazine metabolites and to terciles of nitrate concentrations in each trimester of pregnancy."3.79Drinking-water exposure to a mixture of nitrate and low-dose atrazine metabolites and small-for-gestational age (SGA) babies: a historic cohort study. ( Albouy-Llaty, M; Carles, C; Dupuis, A; Limousi, F; Migeot, V; Rabouan, S; Strezlec, S, 2013)
" Gastroschisis occurred more frequently among those who resided <25 km from a site of high atrazine concentration (odds ratio, 1."3.76Agricultural-related chemical exposures, season of conception, and risk of gastroschisis in Washington State. ( Hitti, JE; Paul, K; Peterson, SE; Waller, SA, 2010)
"Our retrospective cohort study evaluated whether atrazine in drinking water is associated with increased prevalence of SGA and preterm birth."3.75Drinking-water herbicide exposure in Indiana and prevalence of small-for-gestational-age and preterm delivery. ( Carbajo, C; Frankenberger, J; Hahn, L; Ochoa-Acuña, H, 2009)
"To establish an easily reproducible animal model of hypospadias and to test whether Atrazine can induce hypospadias in animal experiment."3.74[The establishment of hypospadias rat model and embryoteratogenic test of Atrazine]. ( Gao, H; Li, SK; Li, YQ; Shou, KR; Wang, YS; Wu, YG; Xin, ZC, 2007)
"2 mg/kg/2x/day to induce hypoprolactinemia or to propylthiouracil (PTU) at 2 mg/kg/day to induce hypothyroidism."3.72Developmental atrazine exposure suppresses immune function in male, but not female Sprague-Dawley rats. ( Luebke, RW; Matulka, RA; Rooney, AA, 2003)
" injections of atrazine and deethylatrazine to rat mothers during pregnancy only or during pregnancy and lactation influenced the pituitary-gonadal axis of male and female offsprings."3.67Indirect influence of s-triazines on rat gonadotropic mechanism at early postnatal period. ( Gojmerac, T; Kniewald, J; Kniewald, Z; Milković, K; Peruzović, M, 1987)
"Atrazine (ATR) is a commonly used agricultural herbicide that has been the subject of epidemiologic studies assessing its relation to reproductive health problems."2.50Atrazine and pregnancy outcomes: a systematic review of epidemiologic evidence. ( DeSesso, JM; Goodman, M; Mandel, JS; Scialli, AR, 2014)
"There is a substantial literature reporting that the developing immune system is more sensitive to toxic insult and that the measurable phenotype resulting from prenatal/neonatal exposure often differs from that seen in adult exposure models (reviewed in Holladay and Steven, and Smialowicz et al."2.44Developmental immunotoxicity of atrazine in rodents. ( Barnett, JB; Brundage, KM; Rowe, AM, 2008)
"Atrazine has been demonstrated with a variety of endocrine disrupting activities and reproductive toxicities."1.62Prenatal exposure to atrazine induces cryptorchidism and hypospadias in F1 male mouse offspring. ( Chen, D; Lawless, J; Sinn, A; Tan, H; Wang, S; Wu, G; Zheng, Z, 2021)
"Dietary administration of ATR did not affect rat reproduction up to a parentally toxic dose of 38."1.40Multigeneration reproduction and male developmental toxicity studies on atrazine in rats. ( Breckenridge, CB; DeSesso, JM; Scialli, AR; White, TE, 2014)
"Atrazine-exposed males were less likely to perform the mating behaviors, and performed them less frequently, than control males."1.40Prenatal exposure to low doses of atrazine affects mating behaviors in male guppies. ( Shenoy, K, 2014)
"Atrazine (ATR) is a widely used chlorotriazine herbicide, a ubiquitous environmental contaminant, and a potential developmental toxicant."1.39Estimation of placental and lactational transfer and tissue distribution of atrazine and its main metabolites in rodent dams, fetuses, and neonates with physiologically based pharmacokinetic modeling. ( Filipov, NM; Fisher, JW; Lin, Z; Ross, MK; Wang, R, 2013)
"Atrazine was administered to pregnant female Long Evans rats from gestation days 13-19 at doses of 0, 6."1.37Quantitative assessment of mammary gland development in female Long Evans rats following in utero exposure to atrazine. ( Breckenridge, CB; Coder, PS; Hovey, RC; Sielken, RL; Tisdel, MO; Wolf, JC, 2011)
"Total birth defects, and eleven of 22 birth defect subcategories, were more likely to occur in live births with LMPs between April and July."1.35Agrichemicals in surface water and birth defects in the United States. ( Huskins, J; Winchester, PD; Ying, J, 2009)
" Timed-pregnant Long-Evans (LE) rats were dosed by gavage on gestational days (GD) 15-19 with 100 mg ATR/kg body weight (BW) or 1% methylcellulose (controls, C)."1.34Atrazine-induced reproductive tract alterations after transplacental and/or lactational exposure in male Long-Evans rats. ( Enoch, RR; Fenton, SE; Rayner, JL; Wolf, DC, 2007)
"We observed no significant effect of acute AMM exposure on body weight gain in dams during the dosing period, weight loss in pups on postnatal day (PND)4, or pubertal timing, as is seen with ATR alone."1.34Mammary gland development as a sensitive end point after acute prenatal exposure to an atrazine metabolite mixture in female Long-Evans rats. ( Enoch, RR; Fenton, SE; Greiner, SN; Rayner, JL; Stanko, JP; Youngblood, GL, 2007)
"Atrazine is a herbicide used extensively worldwide."1.33Atrazine in municipal drinking water and risk of low birth weight, preterm delivery, and small-for-gestational-age status. ( Chevrier, C; Cordier, S; Coutté, MB; Durand, G; Villanueva, CM, 2005)
" These data suggest that the consequences of brief ATR exposure during a critical period of fetal MG development (GD 17-19), are both delayed MG development of the offspring and inadequate nutritional support of F2 offspring, resulting in adverse effects on pup weight gain."1.33Adverse effects of prenatal exposure to atrazine during a critical period of mammary gland growth. ( Enoch, RR; Fenton, SE; Rayner, JL, 2005)
"Atrazine is a widely used herbicide applied to corn, sugar and other crops as a broad leaf weed inhibitor."1.33Immunomodulatory effects of maternal atrazine exposure on male Balb/c mice. ( Barnett, JB; Brundage, KM; Rowe, AM; Schafer, R, 2006)
" While no significant delays in pubertal development were observed in two separate dose-response studies with doses ranging up to 183 mg/kg (OH-ATR), a minor but statistically significant delay in the onset of puberty in a pilot study using OH-ATR raises the possibility that an effect might occur following exposure to higher doses."1.32Pubertal development in female Wistar rats following exposure to propazine and atrazine biotransformation by-products, diamino-S-chlorotriazine and hydroxyatrazine. ( Cooper, RL; Ferrell, JM; Laws, SC; Stoker, TE, 2003)
"Atrazine (ATR) is an herbicide that has been shown to have adverse reproductive effects including alterations in levels of pituitary hormones such as prolactin (prl) and luteinizing hormone (LH) in female LE rats when administered at doses of 200 mg/kg/day for 1 and 3 days."1.31Effect of atrazine on implantation and early pregnancy in 4 strains of rats. ( Cooper, RL; Cummings, AM; Rhodes, BE, 2000)

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.99)18.7374
1990's5 (7.46)18.2507
2000's20 (29.85)29.6817
2010's32 (47.76)24.3611
2020's8 (11.94)2.80

Authors

AuthorsStudies
Pandey, N1
Maske, P1
Mote, C1
Dighe, V1
Kirtana, A1
Seetharaman, B1
Wei, H1
Zhang, X1
Yang, X1
Yu, Q1
Deng, S1
Guan, Q1
Chen, D2
Zhang, M1
Gao, B1
Xu, S1
Xia, Y1
Govers, LC1
Harper, AP2
Finger, BJ2
Mattiske, DM1
Pask, AJ1
Green, MP2
Brandhonneur, N2
Hutin, V1
Chevrier, C4
Cordier, S4
Le Corre, P2
Tan, H1
Wu, G1
Wang, S1
Lawless, J1
Sinn, A1
Zheng, Z1
Carles, C4
Albouy-Llaty, M4
Dupuis, A4
Rabouan, S4
Migeot, V4
Griffiths, MJ1
Winship, AL1
Stringer, JM1
Swindells, EO1
Hutt, KJ1
Sun, Y3
Li, YS2
Li, B4
Ma, K1
Li, BX2
Almberg, KS1
Turyk, ME1
Jones, RM1
Rankin, K1
Freels, S1
Stayner, LT2
Holásková, I1
Elliott, M1
Brundage, K1
Lukomska, E1
Schafer, R2
Barnett, JB3
Wang, D1
Wu, Y2
Agopian, AJ2
Lupo, PJ2
Canfield, MA2
Langlois, PH2
Limousi, F3
Lin, Z2
Fisher, JW1
Wang, R1
Ross, MK1
Filipov, NM2
Serrano, T1
Lecerf, R1
Limon, G2
Petit, C2
Monfort, C2
Hubert-Moy, L1
Durand, G3
Yang, JW1
Yu, J2
Wu, YP1
Scialli, AR3
DeSesso, JM3
Breckenridge, CB3
Goodman, M1
Mandel, JS1
White, TE1
Li, Y1
Yang, J1
Dodd, CA1
Xiao, S1
Krishna, S1
Ye, X1
Shenoy, K1
Sobolewski, M1
Conrad, K1
Allen, JL1
Weston, H1
Martin, K1
Lawrence, BP1
Cory-Slechta, DA1
De Sousa Mendes, M1
Lepvrier, E1
Flejou Esseiva, E1
Chevanne, F1
Walters, JL1
Lansdell, TA1
Lookingland, KJ1
Baker, LE1
Wirbisky, SE1
Weber, GJ1
Sepúlveda, MS1
Lin, TL1
Jannasch, AS1
Freeman, JL1
Brender, JD1
Weyer, PJ1
Winston, JJ1
Emch, M1
Meyer, RE1
Langlois, P1
Weyer, P1
Mosley, B1
Olshan, AF1
Band, LE1
Luben, TJ1
Hao, C1
Gely-Pernot, A1
Kervarrec, C1
Boudjema, M1
Becker, E1
Khil, P1
Tevosian, S1
Jégou, B1
Smagulova, F1
Almberg, K1
Jones, R1
Graber, J1
Pedersen, M1
Turyk, M1
Cimino-Reale, G1
Ferrario, D1
Casati, B1
Brustio, R1
Diodovich, C1
Collotta, A1
Vahter, M1
Gribaldo, L1
Winchester, PD1
Huskins, J1
Ying, J1
Shibayama, H1
Kotera, T1
Shinoda, Y1
Hanada, T1
Kajihara, T1
Ueda, M1
Tamura, H1
Ishibashi, S1
Yamashita, Y1
Ochi, S1
Ochoa-Acuña, H1
Frankenberger, J1
Hahn, L1
Carbajo, C1
Waller, SA1
Paul, K1
Peterson, SE1
Hitti, JE1
Belloni, V2
Dessì-Fulgheri, F1
Zaccaroni, M1
Di Consiglio, E1
De Angelis, G1
Testai, E1
Santochirico, M1
Alleva, E2
Santucci, D2
Stanko, JP2
Enoch, RR4
Rayner, JL5
Davis, CC1
Wolf, DC2
Malarkey, DE1
Fenton, SE7
Hovey, RC1
Coder, PS1
Wolf, JC1
Sielken, RL1
Tisdel, MO1
Rouget, F1
Garlantézec, R1
Lubinsky, M1
Cai, Y1
Strezlec, S1
Birnbaum, LS1
Laws, SC2
Ferrell, JM1
Stoker, TE3
Cooper, RL4
Rooney, AA1
Matulka, RA1
Luebke, RW1
Wood, C1
Villanueva, CM1
Coutté, MB1
Giusi, G1
Facciolo, RM1
Canonaco, M1
Dessi'-Fulgheri, F1
Rowe, AM2
Brundage, KM2
Moon, HJ1
Han, SY1
Shin, JH1
Kang, IH1
Kim, TS1
Hong, JH1
Kim, SH1
Beldomenico, PM1
Rey, F1
Prado, WS1
Villarreal, JC1
Muñoz-de-Toro, M1
Luque, EH1
Das, PC1
Narotsky, MG1
Goldman, JM1
Lee Tyrey, E1
Greiner, SN1
Youngblood, GL1
Wu, YG1
Li, SK1
Xin, ZC1
Wang, YS1
Shou, KR1
Gao, H1
Li, YQ1
Peruzović, M2
Kniewald, J2
Capkun, V1
Milković, K2
Munger, R1
Isacson, P1
Hu, S1
Burns, T1
Hanson, J1
Lynch, CF1
Cherryholmes, K1
Van Dorpe, P1
Hausler, WJ1
Robinette, CL1
Cummings, AM1
Rhodes, BE1
Ugazio, G1
Bosio, A1
Nebbia, C1
Soffietti, MG1
Gojmerac, T1
Kniewald, Z1
Peters, JW1
Cook, RM1

Reviews

8 reviews available for atrazine and Pregnancy

ArticleYear
Comprehending the Role of Endocrine Disruptors in Inducing Epigenetic Toxicity.
    Endocrine, metabolic & immune disorders drug targets, 2022, Volume: 22, Issue:11

    Topics: Androgens; Arsenic; Atrazine; Detergents; Dioxins; Endocrine Disruptors; Epigenesis, Genetic; Female

2022
Atrazine and pregnancy outcomes: a systematic review of epidemiologic evidence.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2014, Volume: 101, Issue:3

    Topics: Abortion, Spontaneous; Animals; Atrazine; Birth Weight; Disease Models, Animal; Female; Fetal Develo

2014
Agricultural Compounds in Water and Birth Defects.
    Current environmental health reports, 2016, Volume: 3, Issue:2

    Topics: Abnormalities, Drug-Induced; Agriculture; Animals; Atrazine; Congenital Abnormalities; Drinking Wate

2016
Hypothesis: Estrogen related thrombosis explains the pathogenesis and epidemiology of gastroschisis.
    American journal of medical genetics. Part A, 2012, Volume: 158A, Issue:4

    Topics: Abdominal Wall; Alcohol Drinking; Animals; Atrazine; Body Mass Index; Estrogens; Female; Gastroschis

2012
Cancer and developmental exposure to endocrine disruptors.
    Environmental health perspectives, 2003, Volume: 111, Issue:4

    Topics: Adult; Animals; Atrazine; Breast Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Child; Chi

2003
Atrazine and reproductive function: mode and mechanism of action studies.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2007, Volume: 80, Issue:2

    Topics: Aging; Animals; Animals, Suckling; Atrazine; Chlorine Compounds; Estrogens; Female; Herbicides; Hypo

2007
Developmental immunotoxicity of atrazine in rodents.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 102, Issue:2

    Topics: Animals; Atrazine; Female; Herbicides; Humans; Immune System; Immunologic Factors; Lactation; Pregna

2008
Atrazine.
    IARC monographs on the evaluation of carcinogenic risks to humans, 1991, Volume: 53

    Topics: Air Pollutants, Occupational; Animals; Atrazine; Carcinogenicity Tests; Case-Control Studies; Cross-

1991

Other Studies

59 other studies available for atrazine and Pregnancy

ArticleYear
Exposure to Atrazine through gestation and lactation period led to impaired sexual maturation and subfertility in F1 male rats with congenital deformities in F2 progeny.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2021, Volume: 157

    Topics: Abnormalities, Drug-Induced; Animals; Atrazine; Dose-Response Relationship, Drug; Female; Infertilit

2021
Prenatal exposure to pesticides and domain-specific neurodevelopment at age 12 and 18 months in Nanjing, China.
    Environment international, 2023, Volume: 173

    Topics: Atrazine; Bayes Theorem; China; Chlorpyrifos; Female; Humans; Infant; Infant, Newborn; Maternal Expo

2023
Atrazine induces penis abnormalities including hypospadias in mice.
    Journal of developmental origins of health and disease, 2020, Volume: 11, Issue:3

    Topics: Animals; Atrazine; Disease Models, Animal; Female; Herbicides; Humans; Hypospadias; Male; Mice; Peni

2020
Maternal and Fetal Blood Pharmacokinetics and Organ Distribution of Atrazine, Propazine, Simazine, and Their Metabolites in Pregnant Rats After Chronic Oral Administration.
    Toxicological sciences : an official journal of the Society of Toxicology, 2020, 02-01, Volume: 173, Issue:2

    Topics: Administration, Oral; Animals; Atrazine; Female; Fetal Blood; Fetus; Herbicides; Organ Size; Pregnan

2020
Prenatal exposure to atrazine induces cryptorchidism and hypospadias in F1 male mouse offspring.
    Birth defects research, 2021, 04-01, Volume: 113, Issue:6

    Topics: Animals; Atrazine; Cryptorchidism; Female; Humans; Hypospadias; Male; Mice; Mice, Inbred ICR; Pregna

2021
Comparison of the Effect on Fetal Growth of a Mixture of Atrazine and Nitrates in Drinking Water and of Active Tobacco Exposure during Pregnancy.
    International journal of environmental research and public health, 2021, 02-23, Volume: 18, Issue:4

    Topics: Atrazine; Birth Weight; Cohort Studies; Drinking Water; Female; Fetal Development; Humans; Infant, N

2021
Prolonged atrazine exposure beginning
    Journal of developmental origins of health and disease, 2022, Volume: 13, Issue:1

    Topics: Animals; Atrazine; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL; Pregnancy; Prenatal Exp

2022
A study of the age-related effects of lactational atrazine exposure.
    Reproductive toxicology (Elmsford, N.Y.), 2017, Volume: 69

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Atrazine; Corpus Striatum; Dopamine; Dopamine

2017
Atrazine Contamination of Drinking Water and Adverse Birth Outcomes in Community Water Systems with Elevated Atrazine in Ohio, 2006⁻2008.
    International journal of environmental research and public health, 2018, 08-31, Volume: 15, Issue:9

    Topics: Adult; Atrazine; Birth Weight; Drinking Water; Female; Gestational Age; Herbicides; Humans; Infant,

2018
Long-term Immunotoxic Effects of Oral Prenatal and Neonatal Atrazine Exposure.
    Toxicological sciences : an official journal of the Society of Toxicology, 2019, 04-01, Volume: 168, Issue:2

    Topics: Animals; Animals, Newborn; Antibodies, Bacterial; Atrazine; Cells, Cultured; Cytokines; Female; Herb

2019
The Effects of Maternal Atrazine Exposure and Swimming Training on Spatial Learning Memory and Hippocampal Morphology in Offspring Male Rats via PSD95/NR2B Signaling Pathway.
    Cellular and molecular neurobiology, 2019, Volume: 39, Issue:7

    Topics: Animals; Atrazine; Body Weight; Disks Large Homolog 4 Protein; Female; Gene Expression Regulation; H

2019
Case-control study of maternal residential atrazine exposure and male genital malformations.
    American journal of medical genetics. Part A, 2013, Volume: 161A, Issue:5

    Topics: Atrazine; Case-Control Studies; Disorders of Sex Development; Endocrine Disruptors; Female; Herbicid

2013
Does area deprivation modify the association between exposure to a nitrate and low-dose atrazine metabolite mixture in drinking water and small for gestational age? A historic cohort study.
    Environmental science and pollution research international, 2014, Volume: 21, Issue:7

    Topics: Adult; Atrazine; Cohort Studies; Drinking Water; Female; France; Gestational Age; Humans; Infant, Sm

2014
Estimation of placental and lactational transfer and tissue distribution of atrazine and its main metabolites in rodent dams, fetuses, and neonates with physiologically based pharmacokinetic modeling.
    Toxicology and applied pharmacology, 2013, Nov-15, Volume: 273, Issue:1

    Topics: Animals; Animals, Newborn; Atrazine; Female; Fetus; Lactation; Male; Maternal Exposure; Maternal-Fet

2013
Environmental determinants of the urinary concentrations of herbicides during pregnancy: the PELAGIE mother-child cohort (France).
    Environment international, 2014, Volume: 63

    Topics: Acetamides; Adult; Animals; Atrazine; Child; Crops, Agricultural; Drinking Water; Environmental Moni

2014
Exposure to atrazine during gestation and lactation periods: toxicity effects on dopaminergic neurons in offspring by downregulation of Nurr1 and VMAT2.
    International journal of molecular sciences, 2014, Feb-18, Volume: 15, Issue:2

    Topics: Animals; Atrazine; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Plasma

2014
Developmental toxicity studies with atrazine and its major metabolites in rats and rabbits.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2014, Volume: 101, Issue:3

    Topics: Animals; Atrazine; Dose-Response Relationship, Drug; Female; Fetal Weight; Fetus; Herbicides; Matern

2014
Multigeneration reproduction and male developmental toxicity studies on atrazine in rats.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2014, Volume: 101, Issue:3

    Topics: Administration, Oral; Animals; Atrazine; Body Weight; Dose-Response Relationship, Drug; Endpoint Det

2014
Age-dependent dopaminergic dysfunction following fetal exposure to atrazine in SD rats.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Atrazine; Corpus Striatum; Dopamine; Dopamine Plasma

2014
Gestational and lactational exposure to atrazine via the drinking water causes specific behavioral deficits and selectively alters monoaminergic systems in C57BL/6 mouse dams, juvenile and adult offspring.
    Toxicological sciences : an official journal of the Society of Toxicology, 2014, Volume: 141, Issue:1

    Topics: Aging; Animals; Atrazine; Behavior, Animal; Corpus Striatum; Dopamine; Drinking Water; Female; Gesta

2014
Prenatal exposure to low doses of atrazine affects mating behaviors in male guppies.
    Hormones and behavior, 2014, Volume: 66, Issue:2

    Topics: Aggression; Animals; Atrazine; Competitive Behavior; Copulation; Environmental Pollutants; Female; H

2014
Sex-specific enhanced behavioral toxicity induced by maternal exposure to a mixture of low dose endocrine-disrupting chemicals.
    Neurotoxicology, 2014, Volume: 45

    Topics: Animals; Atrazine; Behavior, Animal; Benzhydryl Compounds; Caprylates; Dioxins; Drug Combinations; E

2014
A micro-QuEChERS method coupled to GC-MS for the quantification of pesticides in specific maternal and fetal tissues.
    Journal of pharmaceutical and biomedical analysis, 2015, Volume: 104

    Topics: Animals; Atrazine; Brain Chemistry; Female; Fetus; Gas Chromatography-Mass Spectrometry; Limit of De

2015
The effects of gestational and chronic atrazine exposure on motor behaviors and striatal dopamine in male Sprague-Dawley rats.
    Toxicology and applied pharmacology, 2015, Dec-01, Volume: 289, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Atrazine; Behavior, Animal; Cognition; Corpus

2015
An embryonic atrazine exposure results in reproductive dysfunction in adult zebrafish and morphological alterations in their offspring.
    Scientific reports, 2016, Feb-19, Volume: 6

    Topics: Animals; Atrazine; Embryonic Development; Endocrine Disruptors; Estradiol; Female; Gene Expression R

2016
Hypospadias and maternal exposure to atrazine via drinking water in the National Birth Defects Prevention study.
    Environmental health : a global access science source, 2016, 07-15, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Atrazine; Drinking Water; Female; Herbicides; Humans; Hypospadias; Infant, Newbor

2016
Association between Exposure to Endocrine Disruptors in Drinking Water and Preterm Birth, Taking Neighborhood Deprivation into Account: A Historic Cohort Study.
    International journal of environmental research and public health, 2016, 08-09, Volume: 13, Issue:8

    Topics: Adult; Atrazine; Cohort Studies; Drinking Water; Endocrine Disruptors; Female; France; Humans; Infan

2016
Exposure to the widely used herbicide atrazine results in deregulation of global tissue-specific RNA transcription in the third generation and is associated with a global decrease of histone trimethylation in mice.
    Nucleic acids research, 2016, Nov-16, Volume: 44, Issue:20

    Topics: Animals; Atrazine; Binding Sites; Chromatin Immunoprecipitation; Cluster Analysis; Environmental Exp

2016
Atrazine and nitrate in drinking water and the risk of preterm delivery and low birth weight in four Midwestern states.
    Environmental research, 2017, Volume: 152

    Topics: Atrazine; Drinking Water; Female; Herbicides; Humans; Infant, Low Birth Weight; Infant, Newborn; Mal

2017
Combined in utero and juvenile exposure of mice to arsenate and atrazine in drinking water modulates gene expression and clonogenicity of myeloid progenitors.
    Toxicology letters, 2008, Jul-30, Volume: 180, Issue:1

    Topics: Administration, Oral; Animals; Arsenates; Atrazine; Bone Marrow Cells; Clone Cells; Drinking; Drug C

2008
Agrichemicals in surface water and birth defects in the United States.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Agrochemicals; Atrazine; Congenital Abnormalities; Environmental

2009
Collaborative work on evaluation of ovarian toxicity. 14) Two- or four-week repeated-dose studies and fertility study of atrazine in female rats.
    The Journal of toxicological sciences, 2009, Volume: 34 Suppl 1

    Topics: Animals; Atrazine; Body Weight; Copulation; Corpus Luteum; Drug Administration Schedule; Estrous Cyc

2009
Drinking-water herbicide exposure in Indiana and prevalence of small-for-gestational-age and preterm delivery.
    Environmental health perspectives, 2009, Volume: 117, Issue:10

    Topics: Atrazine; Female; Herbicides; Humans; Indiana; Infant, Newborn; Infant, Small for Gestational Age; M

2009
Agricultural-related chemical exposures, season of conception, and risk of gastroschisis in Washington State.
    American journal of obstetrics and gynecology, 2010, Volume: 202, Issue:3

    Topics: Adolescent; Adult; Atrazine; Case-Control Studies; Female; Fertilization; Gastroschisis; Herbicides;

2010
Early exposure to low doses of atrazine affects behavior in juvenile and adult CD1 mice.
    Toxicology, 2011, Jan-11, Volume: 279, Issue:1-3

    Topics: Age Factors; Animals; Atrazine; Behavior, Animal; Cognition; Dose-Response Relationship, Drug; Endoc

2011
Effects of prenatal exposure to a low dose atrazine metabolite mixture on pubertal timing and prostate development of male Long-Evans rats.
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 30, Issue:4

    Topics: Adipose Tissue, White; Adiposity; Animals; Atrazine; Dose-Response Relationship, Drug; Epididymis; F

2010
Quantitative assessment of mammary gland development in female Long Evans rats following in utero exposure to atrazine.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 119, Issue:2

    Topics: Animals; Atrazine; Dose-Response Relationship, Drug; Female; Mammary Glands, Animal; Pregnancy; Pren

2011
Urinary biomarkers of prenatal atrazine exposure and adverse birth outcomes in the PELAGIE birth cohort.
    Environmental health perspectives, 2011, Volume: 119, Issue:7

    Topics: Acetanilides; Acetylcysteine; Adult; Atrazine; Biomarkers; Birth Weight; Cephalometry; Cohort Studie

2011
Maternal residential atrazine exposure and risk for choanal atresia and stenosis in offspring.
    The Journal of pediatrics, 2013, Volume: 162, Issue:3

    Topics: Adult; Atrazine; Choanal Atresia; Constriction, Pathologic; Female; Herbicides; Humans; Infant; Logi

2013
Drinking-water exposure to a mixture of nitrate and low-dose atrazine metabolites and small-for-gestational age (SGA) babies: a historic cohort study.
    Environmental research, 2013, Volume: 122

    Topics: Adult; Atrazine; Cohort Studies; Drinking Water; Environmental Exposure; Female; Fetal Growth Retard

2013
Pubertal development in female Wistar rats following exposure to propazine and atrazine biotransformation by-products, diamino-S-chlorotriazine and hydroxyatrazine.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 76, Issue:1

    Topics: Administration, Oral; Animals; Atrazine; Biotransformation; Body Weight; Female; Herbicides; No-Obse

2003
Developmental atrazine exposure suppresses immune function in male, but not female Sprague-Dawley rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 76, Issue:2

    Topics: Abnormalities, Drug-Induced; Adjuvants, Immunologic; Administration, Oral; Animals; Animals, Sucklin

2003
Exposure parameters necessary for delayed puberty and mammary gland development in Long-Evans rats exposed in utero to atrazine.
    Toxicology and applied pharmacology, 2004, Feb-15, Volume: 195, Issue:1

    Topics: Administration, Oral; Animals; Aromatase; Atrazine; Body Weight; ErbB Receptors; Estrous Cycle; Fema

2004
Atrazine in municipal drinking water and risk of low birth weight, preterm delivery, and small-for-gestational-age status.
    Occupational and environmental medicine, 2005, Volume: 62, Issue:6

    Topics: Adult; Atrazine; Environmental Exposure; Female; Herbicides; Humans; Infant, Low Birth Weight; Infan

2005
Adverse effects of prenatal exposure to atrazine during a critical period of mammary gland growth.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 87, Issue:1

    Topics: Animals; Atrazine; Female; Fetal Weight; Fetus; Gestational Age; Herbicides; Hormones; Mammary Gland

2005
The endocrine disruptor atrazine accounts for a dimorphic somatostatinergic neuronal expression pattern in mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 89, Issue:1

    Topics: Animals; Animals, Newborn; Animals, Outbred Strains; Atrazine; Brain; Dose-Response Relationship, Dr

2006
Immunomodulatory effects of maternal atrazine exposure on male Balb/c mice.
    Toxicology and applied pharmacology, 2006, Jul-01, Volume: 214, Issue:1

    Topics: Animals; Animals, Newborn; Atrazine; B-Lymphocytes; Cells, Cultured; Embryo Loss; Female; Herbicides

2006
Gestational exposure to nonylphenol causes precocious mammary gland development in female rat offspring.
    The Journal of reproduction and development, 2007, Volume: 53, Issue:2

    Topics: Animals; Atrazine; Body Weight; Female; Mammary Glands, Animal; Organ Size; Phenols; Pregnancy; Pren

2007
Atrazine-induced reproductive tract alterations after transplacental and/or lactational exposure in male Long-Evans rats.
    Toxicology and applied pharmacology, 2007, Feb-01, Volume: 218, Issue:3

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Animals, Newborn; Animals, Suckling; Atr

2007
In ovum exposure to pesticides increases the egg weight loss and decreases hatchlings weight of Caiman latirostris (Crocodylia: Alligatoridae).
    Ecotoxicology and environmental safety, 2007, Volume: 68, Issue:2

    Topics: Alligators and Crocodiles; Animals; Animals, Newborn; Atrazine; Body Weight; Embryo, Nonmammalian; E

2007
Mammary gland development as a sensitive end point after acute prenatal exposure to an atrazine metabolite mixture in female Long-Evans rats.
    Environmental health perspectives, 2007, Volume: 115, Issue:4

    Topics: Animals; Atrazine; Endpoint Determination; Environmental Exposure; Female; Herbicides; Humans; Mamma

2007
[The establishment of hypospadias rat model and embryoteratogenic test of Atrazine].
    Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2007, Volume: 23, Issue:4

    Topics: Animals; Atrazine; Disease Models, Animal; Female; Finasteride; Hypospadias; Male; Pregnancy; Rats;

2007
Effect of atrazine ingested prior to mating on rat females and their offspring.
    Acta physiologica Hungarica, 1995, Volume: 83, Issue:1

    Topics: Animals; Animals, Newborn; Atrazine; Behavior, Animal; Body Weight; Conditioning, Operant; Estrus; F

1995
Intrauterine growth retardation in Iowa communities with herbicide-contaminated drinking water supplies.
    Environmental health perspectives, 1997, Volume: 105, Issue:3

    Topics: Atrazine; Female; Fetal Growth Retardation; Herbicides; Humans; Infant, Low Birth Weight; Infant, Ne

1997
Maternal exposure to atrazine during lactation suppresses suckling-induced prolactin release and results in prostatitis in the adult offspring.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 52, Issue:1

    Topics: Animals; Animals, Suckling; Atrazine; Depression, Chemical; DNA; Female; Herbicides; Lactation; Male

1999
Effect of atrazine on implantation and early pregnancy in 4 strains of rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:1

    Topics: Administration, Oral; Animals; Atrazine; Circadian Rhythm; Embryo Implantation; Embryo Loss; Embryon

2000
Age- and sex-related effects on hepatic drug metabolism in rats chronically exposed to dietary atrazine.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 73, Issue:2

    Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Atrazine; Body Weight; Enzyme Induction; Femal

1991
Indirect influence of s-triazines on rat gonadotropic mechanism at early postnatal period.
    Journal of steroid biochemistry, 1987, Volume: 27, Issue:4-6

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Animals; Atrazine; Female; Gonads; Lactation; Male

1987
Effects of atrazine on reproduction in rats.
    Bulletin of environmental contamination and toxicology, 1973, Volume: 9, Issue:5

    Topics: Animals; Atrazine; Diet; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Embryo, Mammalian; Fe

1973