Page last updated: 2024-09-04

atrasentan and Pulmonary Hypertension

atrasentan has been researched along with Pulmonary Hypertension in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's7 (77.78)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aubert, JD; Juillerat-Jeanneret, L1
Eshiro, K; Matsumura, Y; Nishida, M; Okada, Y; Takaoka, M1
Akiyoshi, K; Eshiro, K; Gariepy, CE; Matsumura, Y; Nishida, M; Okada, Y; Takoaka, M; Yanagisawa, M1
Ayach, B; Battistini, B; Blouin, A; Cernacek, P; Jeng, AY; Opgenorth, T; Tsang, J; Verreault, M; Wessale, J1
Shi, GY1
Demirakca, S; Dieckmann, R; Gebhard, MM; Gorenflo, M; Hagl, S; Herpel, E; Klimpel, H; Neumayer, S; Ullmann, MV1
Chen, SJ; Chen, YF; DiCarlo, VS; Durand, J; Meng, QC; Oparil, S; Opgenorth, TJ; Wessale, JL1
Chen, YF; Oparil, S1
Battistini, B; Cloutier, R; Crochetière, J; Fournier, L; Jean, S; Kavanagh, M; Major, D; Opgenorth, TJ; Wessale, J1

Reviews

2 review(s) available for atrasentan and Pulmonary Hypertension

ArticleYear
Endothelin-Receptor Antagonists beyond Pulmonary Arterial Hypertension: Cancer and Fibrosis.
    Journal of medicinal chemistry, 2016, 09-22, Volume: 59, Issue:18

    Topics: Animals; Cardiovascular Diseases; Clinical Trials as Topic; Endothelin Receptor Antagonists; Fibrosis; Humans; Hypertension, Pulmonary; Neoplasms; Receptors, Endothelin

2016
Endothelial dysfunction in the pulmonary vascular bed.
    The American journal of the medical sciences, 2000, Volume: 320, Issue:4

    Topics: Animals; Antihypertensive Agents; Atrasentan; Bosentan; Controlled Clinical Trials as Topic; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Endothelium, Vascular; Epoprostenol; Heart Failure; Humans; Hypertension, Pulmonary; Hypoxia; Lung Diseases, Obstructive; Nitric Oxide; Oligopeptides; Peptides, Cyclic; Piperidines; Pulmonary Circulation; Pyrrolidines; Receptors, Endothelin; RNA, Messenger; Sulfonamides; Time Factors; Vasoconstriction; Vasodilation

2000

Other Studies

7 other study(ies) available for atrasentan and Pulmonary Hypertension

ArticleYear
Roles of endothelin ETA and ETB receptors in the pathogenesis of monocrotaline-induced pulmonary hypertension.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:2

    Topics: Administration, Oral; Animals; Atrasentan; Blood Pressure; Body Mass Index; Body Weight; Cardiomegaly; Drug Administration Schedule; Drug Therapy, Combination; Heart; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Injections, Subcutaneous; Intubation, Gastrointestinal; Lung; Male; Monocrotaline; Organ Size; Pulmonary Artery; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Time Factors; Tunica Media; Ventricular Pressure

2004
Role of endothelin ETB receptor in the pathogenesis of monocrotaline-induced pulmonary hypertension in rats.
    European journal of pharmacology, 2004, Aug-02, Volume: 496, Issue:1-3

    Topics: Animals; Animals, Genetically Modified; Atrasentan; Endothelin B Receptor Antagonists; Hypertension, Pulmonary; Monocrotaline; Pulmonary Artery; Pyrrolidines; Rats; Rats, Mutant Strains; Receptor, Endothelin B; Ventricular Function, Right

2004
Role of the endothelin system in secondary pulmonary hypertension related to air embolism: lessons learned from testing four classes of endothelin blockers in a rat model.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Acute Disease; Animals; Aspartic Acid Endopeptidases; Atrasentan; Benzofurans; Cardiovascular Agents; Disease Models, Animal; Embolism, Air; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-Converting Enzymes; Endothelins; Hemodynamics; Hypertension, Pulmonary; Male; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Sulfonamides; Time Factors; Ventricular Dysfunction, Right

2004
[New choice of therapy of pulmonary hypertension: endothelin receptor antagonist].
    Zhonghua yi xue za zhi, 2005, Jan-26, Volume: 85, Issue:4

    Topics: Adult; Atrasentan; Bosentan; Endothelin Receptor Antagonists; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Phenylpropionates; Pyrimidines; Pyrrolidines; Sulfonamides

2005
Atrasentan treatment of pulmonary vascular disease in piglets with increased pulmonary blood flow.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:3

    Topics: Animals; Atrasentan; Blood Pressure; Cardiac Output; Chronic Disease; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin-1; Gene Expression Regulation; Hypertension, Pulmonary; Hypertrophy; Immunohistochemistry; Lung; Pulmonary Artery; Pulmonary Circulation; Pyrrolidines; Random Allocation; Receptor, Endothelin B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Vascular Endothelial Growth Factor A

2007
The orally active nonpeptide endothelin A-receptor antagonist A-127722 prevents and reverses hypoxia-induced pulmonary hypertension and pulmonary vascular remodeling in Sprague-Dawley rats.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:6

    Topics: Animals; Atrasentan; Blood Pressure; Cardiomegaly; Endothelin Receptor Antagonists; Endothelin-1; Heart Rate; Hypertension, Pulmonary; Hypoxia; Male; Pulmonary Artery; Pyrrolidines; Rats; Receptor, Endothelin A

1997
Effect of ABT-627 (A-147627), a potent selective ET(A) receptor antagonist, on the cardiopulmonary profile of newborn lambs with surgically-induced diaphragmatic hernia.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: Animals; Animals, Newborn; Atrasentan; Blood Pressure; Endothelin Receptor Antagonists; Female; Hemodynamics; Hernia, Diaphragmatic; Hypertension, Pulmonary; Infusions, Intravenous; Lung; Matched-Pair Analysis; Oxygen; Pregnancy; Pulmonary Gas Exchange; Pyrrolidines; Receptor, Endothelin A; Respiration; Sheep; Time Factors

2001