Page last updated: 2024-09-04

atrasentan and Proteinuria

atrasentan has been researched along with Proteinuria in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (28.57)18.2507
2000's3 (21.43)29.6817
2010's5 (35.71)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Alpers, CE; Hudkins, KL; Steegh, F; Wietecha, TA1
Andreucci, M; De Nicola, L; Garofalo, C; Minutolo, R; Provenzano, M; Serra, R1
Egido, J; Gomez-Guerrero, C; Gonzalez Parra, E; Mas, S; Rojas-Rivera, J; Ruiz-Ortega, M; Sanz, AB1
Lin, L; Liu, Y; Tan, RJ; Zhou, D; Zhou, L1
Chang, NC; Chung, TH; Lee, TM; Lin, SZ1
Jeon, Y; Jin, C; Kleven, DT; Pollock, DM; Pollock, JS; White, JJ1
Ritz, E; Wenzel, RR1
Horio, T; Johnson, RJ; Kangawa, K; Kawano, Y; Suga, S; Yasui, N; Yoshihara, F1
Bäcker, A; Cervenka, L; Kramer, HJ; Opocensky, M; Vanêcková, I; Vernerová, Z1
Bäcker, A; Cervenka, L; Dvorák, P; Eis, V; Kramer, HJ; Opocenský, M; Schejbalová, S; Vanecková, I; Vernerová, Z1
Polakowski, JS; Pollock, DM1
Opgenorth, TJ; Polakowski, JS; Pollock, DM; Wegner, CD1
Clower, B; Granger, JP; Kassab, S; Miller, MT; Novak, J; Reckelhoff, J1
Blezer, EL; Goldschmeding, R; Jansen, GH; Joles, JA; Koomans, HA; Nicolay, K; Rabelink, TJ1

Reviews

2 review(s) available for atrasentan and Proteinuria

ArticleYear
Selective endothelin A receptor antagonism in patients with proteinuric chronic kidney disease.
    Expert opinion on investigational drugs, 2021, Volume: 30, Issue:3

    Topics: Animals; Atrasentan; Diabetic Nephropathies; Disease Progression; Endothelin A Receptor Antagonists; Humans; Proteinuria; Randomized Controlled Trials as Topic; Receptor, Endothelin A; Renal Insufficiency, Chronic

2021
Atrasentan for the treatment of diabetic nephropathy.
    Expert opinion on investigational drugs, 2017, Volume: 26, Issue:6

    Topics: Animals; Atrasentan; Diabetic Nephropathies; Endothelin Receptor Antagonists; Endothelin-1; Humans; Proteinuria; Pyrrolidines; Renal Insufficiency, Chronic

2017

Other Studies

12 other study(ies) available for atrasentan and Proteinuria

ArticleYear
Beneficial effect on podocyte number in experimental diabetic nephropathy resulting from combined atrasentan and RAAS inhibition therapy.
    American journal of physiology. Renal physiology, 2020, 05-01, Volume: 318, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrasentan; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Drug Therapy, Combination; Endothelin A Receptor Antagonists; Female; Losartan; Mice; Phosphorylation; Podocytes; Proteinuria; Renin-Angiotensin System; Ribosomal Protein S6 Kinases; TOR Serine-Threonine Kinases

2020
Endothelin receptor a blockade is an ineffective treatment for adriamycin nephropathy.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Atrasentan; Disease Models, Animal; Doxorubicin; Endothelin A Receptor Antagonists; Fibrosis; Gene Expression; Kidney Diseases; Kidney Glomerulus; Male; Mice; Podocytes; Proteinuria; Pyrrolidines; Receptor, Endothelin A

2013
Endothelin receptor blockade ameliorates renal injury by inhibition of RhoA/Rho-kinase signalling in deoxycorticosterone acetate-salt hypertensive rats.
    Journal of hypertension, 2014, Volume: 32, Issue:4

    Topics: Animals; Atrasentan; Blood Pressure; Desoxycorticosterone Acetate; Endothelin Receptor Antagonists; Endothelin-1; Fibrosis; Gene Expression Regulation; Hypertension; Kidney; Male; Proteinuria; Pyrrolidines; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Sodium Chloride, Dietary

2014
Combined endothelin a blockade and chlorthalidone treatment in a rat model of metabolic syndrome.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 351, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antihypertensive Agents; Arterial Pressure; Atrasentan; Cell Adhesion Molecules; Chlorthalidone; Deoxyguanosine; Disease Models, Animal; Diuretics; Drug Combinations; Endothelin A Receptor Antagonists; Endothelins; Hypertension; Inflammation; Kidney Diseases; Male; Membrane Proteins; Metabolic Syndrome; Oxidative Stress; Proteinuria; Pyrrolidines; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Receptor, Endothelin A; Sodium Chloride, Dietary

2014
Endothelin antagonist as add-on treatment for proteinuria in diabetic nephropathy: is there light at the end of the tunnel?
    Journal of the American Society of Nephrology : JASN, 2011, Volume: 22, Issue:4

    Topics: Albuminuria; Atrasentan; Diabetic Nephropathies; Endothelins; Glomerular Filtration Rate; Humans; Proteinuria; Pyridines; Pyrimidines; Pyrrolidines; Renin-Angiotensin System; Treatment Outcome

2011
Endothelin a receptor blockade and endothelin B receptor blockade improve hypokalemic nephropathy by different mechanisms.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:2

    Topics: Albuminuria; Animals; Atrasentan; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Hypertrophy; Hypokalemia; Kidney; Kidney Diseases; Kidney Tubules; Male; Potassium; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B

2003
Early endothelin-A receptor blockade decreases blood pressure and ameliorates end-organ damage in homozygous Ren-2 rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4

    Topics: Animals; Animals, Genetically Modified; Atrasentan; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Endothelin A Receptor Antagonists; Endothelin-1; Glomerulosclerosis, Focal Segmental; Heart Ventricles; Hypertension; Kidney; Male; Myocardium; Organ Size; Osmolar Concentration; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Renin; Sodium Chloride, Dietary; Sulfonamides; Survival Analysis

2005
Early-onset endothelin receptor blockade in hypertensive heterozygous Ren-2 rats.
    Vascular pharmacology, 2006, Volume: 45, Issue:3

    Topics: Animals; Animals, Genetically Modified; Antihypertensive Agents; Atrasentan; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin Receptor Antagonists; Endothelin-1; Glomerulosclerosis, Focal Segmental; Heterozygote; Hypertension; Male; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Renin; Sodium Chloride, Dietary; Sulfonamides; Time Factors

2006
ETA receptor blockade prevents hypertension associated with exogenous endothelin-1 but not renal mass reduction in the rat.
    Journal of the American Society of Nephrology : JASN, 1997, Volume: 8, Issue:7

    Topics: Administration, Oral; Animals; Atrasentan; Blood Pressure; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hypertension, Renal; Kidney; Kidney Failure, Chronic; Male; Nephrectomy; Protein Precursors; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A

1997
Beneficial effect of ETA receptor blockade in a rat model of radiocontrast-induced nephropathy.
    Renal failure, 1997, Volume: 19, Issue:6

    Topics: Acute Kidney Injury; Animals; Atrasentan; Contrast Media; Creatinine; Diatrizoate; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Antagonists; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Stereoisomerism

1997
Endothelin-A receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Animals; Atrasentan; Blood Pressure; Diet, Sodium-Restricted; Endothelin Receptor Antagonists; Glomerular Filtration Rate; Hemodynamics; Hypertension; Kidney; Male; Natriuresis; Potassium; Proteinuria; Pyrrolidines; Rats; Rats, Inbred Strains; Receptor, Endothelin A; Regional Blood Flow; Sodium; Sodium, Dietary; Systole

1998
Early-onset but not late-onset endothelin-A-receptor blockade can modulate hypertension, cerebral edema, and proteinuria in stroke-prone hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1

    Topics: Animals; Atrasentan; Blood Pressure; Brain Edema; Data Interpretation, Statistical; Endothelin Receptor Antagonists; Hypertension; Hypertension, Malignant; Kidney; Magnetic Resonance Imaging; Male; Proteinuria; Pyrrolidines; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Stereoisomerism; Time Factors

1999