Page last updated: 2024-09-04

atrasentan and Heart Failure

atrasentan has been researched along with Heart Failure in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.67)18.2507
2000's7 (46.67)29.6817
2010's1 (6.67)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Bakris, GL; Correa-Rotter, R; de Zeeuw, D; Gansevoort, RT; Heerspink, HJL; Hou, FF; Kitzman, DW; Kohan, DE; Makino, H; McMurray, JJV; Parving, HH; Perkovic, V; Tobe, S; Waijer, SW1
Bakris, GL; Correa-Rotter, R; de Zeeuw, D; Heerspink, HJL; Hou, FF; Januzzi, JL; Kitzman, DW; Kohan, DE; Kolansky, DM; Koomen, J; Makino, H; McMurray, JJV; Parving, HH; Perkovic, V; Smeijer, JD; Tobe, S1
Červenka, L; Gawrys, O; Jíchová, Š; Kala, P; Kompanowska-Jezierska, E; Maxová, H; Miklovič, M; Sadowski, J; Škaroupková, P; Táborský, M; Vaněčková, I; Vaňourková, Z; Veselka, J; Walkowska, A1
de Zeeuw, D; Heerspink, HJL; Kohan, DE; Smeijer, JD1
Chi, J; Dong, B; Huang, Y; Lv, W; Wang, YG; Zhou, Y1
Bakris, G; Correa-Rotter, R; de Zeeuw, D; Heerspink, HJL; Hou, FF; Kitzman, DW; Kohan, DE; Koomen, JV; Makino, H; McMurray, JJV; Parving, HH; Perkovic, V; Stevens, J; Tobe, SW1
Andress, D; Brennan, JJ; Coll, B; Correa-Rotter, R; de Zeeuw, D; Hoekman, J; Hou, FF; Kitzman, DW; Kohan, D; Lambers Heerspink, HJ; Makino, H; Parving, HH; Perkovic, V; Remuzzi, G; Schievink, B; Smink, PA; Tobe, S; Toto, R1
Bkaily, G; Carrier, E; D'Orleans-Juste, P; Fecteau, MH; Honoré, JC; Tirapelli, CR1
Abassi, Z; Francis, B; Hoffman, A; Ovcharenko, E; Wessale, J; Winaver, J1
Austin, PC; Lapointe, N; Lee, DS; Nguyen, QT; Ohlsson, A; Rouleau, JL; Stewart, DJ; Tu, JV1
Abassi, Z; Francis, B; Hoffman, A; Karram, T; Winaver, J1
Borgeson, DD; Burnett, JC; Grantham, JA; Luchner, A; Opgenorth, TJ; Redfield, MM; Williamson, EE1
Boujedaini, H; Derumeaux, G; Henry, JP; Mulder, P; Opgenorth, T; Renet, S; Richard, V; Thuillez, C; Wessale, J1
Chen, YF; Oparil, S1
Enseleit, F; Hürlimann, D; Lüscher, TF; Noll, G; Ruschitzka, F1

Reviews

4 review(s) available for atrasentan and Heart Failure

ArticleYear
Efficacy and safety of endothelin receptor antagonists in type 2 diabetic kidney disease: A systematic review and meta-analysis of randomized controlled trials.
    Diabetic medicine : a journal of the British Diabetic Association, 2021, Volume: 38, Issue:1

    Topics: Albuminuria; Atrasentan; Bosentan; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelin Receptor Antagonists; Heart Failure; Humans; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic

2021
Meta-analysis of the effects of endothelin receptor blockade on survival in experimental heart failure.
    Journal of cardiac failure, 2003, Volume: 9, Issue:5

    Topics: Animals; Atrasentan; Cardiotonic Agents; Endothelin Receptor Antagonists; Heart Failure; Peptides, Cyclic; Phenylpropionates; Pyrimidines; Pyrrolidines; Rats; Risk; Survival Rate

2003
Endothelial dysfunction in the pulmonary vascular bed.
    The American journal of the medical sciences, 2000, Volume: 320, Issue:4

    Topics: Animals; Antihypertensive Agents; Atrasentan; Bosentan; Controlled Clinical Trials as Topic; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Endothelium, Vascular; Epoprostenol; Heart Failure; Humans; Hypertension, Pulmonary; Hypoxia; Lung Diseases, Obstructive; Nitric Oxide; Oligopeptides; Peptides, Cyclic; Piperidines; Pulmonary Circulation; Pyrrolidines; Receptors, Endothelin; RNA, Messenger; Sulfonamides; Time Factors; Vasoconstriction; Vasodilation

2000
Endothelin antagonists and heart failure.
    Current hypertension reports, 2002, Volume: 4, Issue:1

    Topics: Atrasentan; Bosentan; Endothelin Receptor Antagonists; Endothelins; Heart Failure; Hemodynamics; Humans; Hypertension; Pyrrolidines; Receptors, Endothelin; Sulfonamides

2002

Trials

4 trial(s) available for atrasentan and Heart Failure

ArticleYear
The Effect of Atrasentan on Kidney and Heart Failure Outcomes by Baseline Albuminuria and Kidney Function: A
    Clinical journal of the American Society of Nephrology : CJASN, 2021, Volume: 16, Issue:12

    Topics: Albuminuria; Atrasentan; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Glomerular Filtration Rate; Heart Failure; Humans; Kidney; Renal Insufficiency; Renal Insufficiency, Chronic

2021
Increase in BNP in Response to Endothelin-Receptor Antagonist Atrasentan Is Associated With Incident Heart Failure.
    JACC. Heart failure, 2022, Volume: 10, Issue:7

    Topics: Atrasentan; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Endothelin Receptor Antagonists; Endothelins; Heart Failure; Humans; Natriuretic Peptide, Brain; Renal Insufficiency, Chronic; Weight Gain

2022
Individual Atrasentan Exposure is Associated With Long-term Kidney and Heart Failure Outcomes in Patients With Type 2 Diabetes and Chronic Kidney Disease.
    Clinical pharmacology and therapeutics, 2021, Volume: 109, Issue:6

    Topics: Aged; Area Under Curve; Atrasentan; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Endothelin Receptor Antagonists; Female; Glomerular Filtration Rate; Heart Failure; Humans; Kidney Failure, Chronic; Male; Middle Aged; Treatment Outcome

2021
Prediction of the effect of atrasentan on renal and heart failure outcomes based on short-term changes in multiple risk markers.
    European journal of preventive cardiology, 2016, Volume: 23, Issue:7

    Topics: Aged; Atrasentan; Biomarkers; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Female; Follow-Up Studies; Glomerular Filtration Rate; Heart Failure; Humans; Kidney; Male; Middle Aged; Pyrrolidines; Renal Insufficiency, Chronic; Time Factors; Treatment Outcome

2016

Other Studies

7 other study(ies) available for atrasentan and Heart Failure

ArticleYear
Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension.
    Journal of hypertension, 2023, 01-01, Volume: 41, Issue:1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Endothelin-1; Endothelins; Fistula; Heart Failure; Hypertension; Rats; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptor, Endothelin A

2023
Diuretic medication and change in fluid retention biomarkers during treatment with the endothelin receptor antagonist atrasentan.
    Diabetes, obesity & metabolism, 2023, Volume: 25, Issue:8

    Topics: Atrasentan; Biomarkers; Diabetic Nephropathies; Diuretics; Endothelin A Receptor Antagonists; Endothelin Receptor Antagonists; Heart Failure; Humans; Pyrrolidines

2023
Nonselective ETA/ETB-receptor blockade increases systemic blood pressure of Bio 14.6 cardiomyopathic hamsters.
    Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:6

    Topics: Animals; Atrasentan; Blood Pressure; Cardiomyopathies; Cricetinae; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Heart Failure; Hemodynamics; Mesocricetus; Nitrates; Nitrites; Pyrrolidines; Receptor, Endothelin A; Receptor, Endothelin B; Ventricular Function, Left

2008
Effects of endothelin receptors ET(A) and ET(B) blockade on renal haemodynamics in normal rats and in rats with experimental congestive heart failure.
    Clinical science (London, England : 1979), 2002, Volume: 103 Suppl 48

    Topics: Animals; Atrasentan; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Glomerular Filtration Rate; Heart Failure; Kidney; Male; Pyrrolidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Renal Circulation; Vascular Resistance

2002
Renal and systemic effects of chronic blockade of ET(A) or ET(B) receptors in normal rats and animals with experimental heart failure.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Animals; Atrasentan; Blood Pressure; Cardiomegaly; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Heart Failure; Hemodynamics; Infusion Pumps, Implantable; Kidney; Male; Natriuresis; Pyrrolidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Time Factors; Vasoconstriction; Vasodilation

2004
Chronic oral endothelin type A receptor antagonism in experimental heart failure.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:3

    Topics: Administration, Oral; Animals; Atrasentan; Atrial Natriuretic Factor; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Heart; Heart Failure; Hemodynamics; Kidney; Male; Pyrrolidines; Receptor, Endothelin A; Sodium; Vasoconstriction

1998
Selective endothelin-A versus combined endothelin-A/endothelin-B receptor blockade in rat chronic heart failure.
    Circulation, 2000, Aug-01, Volume: 102, Issue:5

    Topics: Animals; Atrasentan; Blood Pressure; Collagen; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Hemodynamics; Myocardial Infarction; Myocardium; Pyrrolidines; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Ventricular Function, Left

2000