Page last updated: 2024-09-04

atrasentan and Bone Cancer

atrasentan has been researched along with Bone Cancer in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (64.71)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agarwal, N; Carducci, MA; Garzotto, MG; Goldkorn, A; Higano, CS; Hussain, M; Lara, PN; Mack, PC; Moinpour, CM; Monk, JP; Quinn, DI; Tangen, CM; Thompson, IM; Twardowski, PW; Van Veldhuizen, PJ; Vogelzang, NJ1
Taneja, SS1
Ely, B; Gertz, E; Goldkorn, A; Hussain, M; Lara, PN; Mack, PC; Quinn, DI; Tangen, C; Thompson, IM; Twardowski, PW; Van Loan, MD; Vogelzang, NJ1
Carducci, MA; Dutcher, JP; Liu, G; Manola, J; Nair, SG; Rousey, S; Wilding, G1
Danke, JR; Drake, JM; Henry, MD1
Abdulkadir, SA; Roh, M1
Garber, K1
Carducci, MA; Lassiter, LK1
Ghilardi, JR; Lindsay, TH; Luger, NM; Mantyh, PW; Peters, CM; Pomonis, JD; Sevcik, MA1
Carducci, M; Jimeno, A1
Clines, GA; Guise, TA1
Kantoff, P; Kaufman, DS; Michaelson, MD; Oh, WK; Smith, MR1
Carducci, MA; Jimeno, A1
Banerjee, S; Bonfil, D; Che, M; Cher, M; Hussain, M; Saliganan, A; Sarkar, FH; Wang, Z1
Abrahamsson, PA; Carducci, MA; Dearnaley, DP; Isaacson, JD; Nelson, JB; North, SA; Saad, F; Schulman, CC; Sleep, DJ1
Nelson, JB1

Reviews

4 review(s) available for atrasentan and Bone Cancer

ArticleYear
Endothelin receptor antagonists in the treatment of prostate cancer.
    Seminars in oncology, 2003, Volume: 30, Issue:5

    Topics: Androgen Antagonists; Apoptosis; Atrasentan; Bone Neoplasms; Bosentan; Clinical Trials as Topic; Disease Progression; Drug Resistance, Neoplasm; Endothelin Receptor Antagonists; Endothelins; Forecasting; Humans; Male; Neovascularization, Pathologic; Prostatic Neoplasms; Pyrimidines; Pyrrolidines; Receptors, Endothelin; Sulfonamides; Treatment Outcome

2003
Atrasentan: a novel and rationally designed therapeutic alternative in the management of cancer.
    Expert review of anticancer therapy, 2005, Volume: 5, Issue:3

    Topics: Apoptosis; Atrasentan; Bone Neoplasms; Clinical Trials as Topic; Disease Progression; Endothelins; Humans; Male; Neovascularization, Pathologic; Prostatic Neoplasms; Pyrrolidines

2005
Mechanisms and treatment for bone metastases.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:5

    Topics: Animals; Atrasentan; Bone Neoplasms; Cell Adhesion Molecules; Cytokines; Diphosphonates; Endothelin-1; Female; Gene Expression Regulation, Neoplastic; Humans; Hypercalcemia; Immunotherapy; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Nude; Neoplasm Proteins; Osteoblasts; Osteolysis; Pain; Pain Management; Pyrrolidines; Xenograft Model Antitumor Assays

2004
Targeting bone metastasis in prostate cancer with endothelin receptor antagonists.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Oct-15, Volume: 12, Issue:20 Pt 2

    Topics: Antineoplastic Agents; Atrasentan; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Endothelin Receptor Antagonists; Female; Humans; Male; Prostatic Neoplasms; Pyrrolidines

2006

Trials

5 trial(s) available for atrasentan and Bone Cancer

ArticleYear
Docetaxel and atrasentan versus docetaxel and placebo for men with advanced castration-resistant prostate cancer (SWOG S0421): a randomised phase 3 trial.
    The Lancet. Oncology, 2013, Volume: 14, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Atrasentan; Bone Neoplasms; Castration; Docetaxel; Double-Blind Method; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasms, Hormone-Dependent; Prognosis; Prostatic Neoplasms; Pyrrolidines; Survival Rate; Taxoids

2013
Serum biomarkers of bone metabolism in castration-resistant prostate cancer patients with skeletal metastases: results from SWOG 0421.
    Journal of the National Cancer Institute, 2014, Volume: 106, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Amino Acids; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Atrasentan; Biomarkers, Tumor; Bone Neoplasms; Bone Remodeling; Collagen Type I; Disease-Free Survival; Docetaxel; Double-Blind Method; Endothelin A Receptor Antagonists; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Molecular Targeted Therapy; Peptide Fragments; Peptides; Predictive Value of Tests; Procollagen; Prognosis; Proportional Hazards Models; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Pyrrolidines; ROC Curve; Taxoids; Treatment Failure

2014
Atrasentan in Patients With Advanced Renal Cell Carcinoma: A Phase 2 Trial of the ECOG-ACRIN Cancer Research Group (E6800).
    Clinical genitourinary cancer, 2015, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Atrasentan; Bone Neoplasms; Carcinoma, Renal Cell; Disease-Free Survival; Endothelin Receptor Antagonists; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Pyrrolidines; Treatment Outcome

2015
Randomized phase II study of atrasentan alone or in combination with zoledronic acid in men with metastatic prostate cancer.
    Cancer, 2006, Aug-01, Volume: 107, Issue:3

    Topics: Aged; Aged, 80 and over; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Atrasentan; Biomarkers, Tumor; Bone and Bones; Bone Density Conservation Agents; Bone Neoplasms; Diphosphonates; Disease Progression; Dyspnea; Edema; Humans; Imidazoles; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Pyrrolidines; Treatment Outcome; Zoledronic Acid

2006
A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer.
    Cancer, 2007, Nov-01, Volume: 110, Issue:9

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Alkaline Phosphatase; Antineoplastic Agents; Atrasentan; Bone Neoplasms; Disease Progression; Double-Blind Method; Drug Resistance, Neoplasm; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Pyrrolidines

2007

Other Studies

8 other study(ies) available for atrasentan and Bone Cancer

ArticleYear
Re: docetaxel and atrasentan versus docetaxel and placebo for men with advanced castration-resistant prostate cancer (SWOG S0421): a randomised phase 3 trial.
    The Journal of urology, 2014, Volume: 191, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Atrasentan; Bone Neoplasms; Castration; Clinical Trials, Phase III as Topic; Docetaxel; Double-Blind Method; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasms, Hormone-Dependent; Prognosis; Prostatic Neoplasms; Pyrrolidines; Randomized Controlled Trials as Topic; Survival Rate; Taxoids

2014
Bone-specific growth inhibition of prostate cancer metastasis by atrasentan.
    Cancer biology & therapy, 2010, Apr-15, Volume: 9, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Atrasentan; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; Humans; Male; Mice; Prostatic Neoplasms; Pyrrolidines; Random Allocation; Xenograft Model Antitumor Assays

2010
Targeting the endothelin receptor in prostate cancer bone metastasis: Back to the mouse?
    Cancer biology & therapy, 2010, Apr-15, Volume: 9, Issue:8

    Topics: Animals; Atrasentan; Bone Neoplasms; Disease Models, Animal; Endothelin Receptor Antagonists; Humans; Male; Mice; Molecular Targeted Therapy; Prostatic Neoplasms; Pyrrolidines

2010
Why it hurts: researchers seek mechanisms of cancer pain.
    Journal of the National Cancer Institute, 2003, Jun-04, Volume: 95, Issue:11

    Topics: Acidosis; Analgesics; Animals; Antineoplastic Agents; Atrasentan; Bone Neoplasms; Diphosphonates; Disease Models, Animal; Glycoproteins; Humans; Ion Channels; Neoplasms; Osteoprotegerin; Pain; Pyrrolidines; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor

2003
Endothelin and the tumorigenic component of bone cancer pain.
    Neuroscience, 2004, Volume: 126, Issue:4

    Topics: Analysis of Variance; Animals; Atrasentan; Behavior, Animal; Bone Neoplasms; Calcitonin Gene-Related Peptide; Disease Models, Animal; Dynorphins; Endothelin Receptor Antagonists; Endothelin-1; Ganglia, Spinal; Gene Expression Regulation, Neoplastic; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Pain; Pain Measurement; Pyrrolidines; Receptors, Endothelin; Sarcoma; Sciatic Nerve; Time Factors

2004
In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer.
    Cancer research, 2007, Apr-15, Volume: 67, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Atrasentan; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; DNA, Neoplasm; Docetaxel; Drug Synergism; Endothelin A Receptor Antagonists; Humans; Male; Mice; Mice, SCID; NF-kappa B; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Taxoids; Xenograft Model Antitumor Assays

2007
Atrasentan prolongs time to progression in prostate cancer patients.
    Oncology (Williston Park, N.Y.), 2001, Volume: 15, Issue:7

    Topics: Antineoplastic Agents; Atrasentan; Biomarkers, Tumor; Bone Neoplasms; Disease Progression; Drug Administration Schedule; Humans; Male; Multicenter Studies as Topic; Prostatic Neoplasms; Pyrrolidines; Randomized Controlled Trials as Topic

2001
Endothelin receptor antagonists in the treatment of prostate cancer.
    The Prostate, 2001, Oct-01, Volume: 49, Issue:2

    Topics: Antineoplastic Agents; Atrasentan; Bone Neoplasms; Bone Resorption; Disease Progression; Endothelin Receptor Antagonists; Humans; Male; Prostatic Neoplasms; Pyrrolidines; Randomized Controlled Trials as Topic

2001