Page last updated: 2024-09-04

atrasentan and Albuminuria

atrasentan has been researched along with Albuminuria in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.56)29.6817
2010's12 (66.67)24.3611
2020's5 (27.78)2.80

Authors

AuthorsStudies
Bakris, G; Correa-Rotter, R; de Zeeuw, D; Heerspink, HJL; Hou, FF; Kitzman, DW; Kohan, D; Makino, H; McMurray, JJV; Parving, HH; Perkovic, V; Rossing, P; Xie, D1
Bakris, GL; Correa-Rotter, R; de Zeeuw, D; Gansevoort, RT; Heerspink, HJL; Hou, FF; Kitzman, DW; Kohan, DE; Makino, H; McMurray, JJV; Parving, HH; Perkovic, V; Tobe, S; Waijer, SW1
Fernandez-Fernandez, B; Ortiz, A1
Chi, J; Dong, B; Huang, Y; Lv, W; Wang, YG; Zhou, Y1
Bakris, G; Correa-Rotter, R; de Zeeuw, D; Heerspink, HJL; Hou, FF; Kitzman, DW; Kohan, D; Koomen, JV; Makino, H; McMurray, JJV; Parving, HH; Perkovic, V; Stevens, J; Tobe, SW1
Awni, WM; J Brennan, J; Klein, CE; L Andress, D; Lin, CW; Mostafa, NM1
de Zeeuw, D; Heerspink, HJL; Koomen, JV; Mostafa, NM; Parving, HH; Stevens, J1
Andress, D; Brennan, JJ; Coll, B; Correa-Rotter, R; de Zeeuw, D; Houser, M; Kohan, D; Lambers Heerspink, HJ; Makino, H; Parving, HH; Perkovic, V; Pritchett, Y; Remuzzi, G; Tang, H; Tobe, SW; Toto, R; Viberti, G1
Andress, DL; Bijlsma, MJ; de Zeeuw, D; Heerspink, HJ; Kröpelin, TF; Parving, HH; Persson, F1
Andress, D; Brennan, JJ; Coll, B; Correa-Rotter, R; de Zeeuw, D; Hou, FF; Kitzman, DW; Kohan, DE; Lambers Heerspink, HJ; Makino, H; Parving, HH; Perkovic, V; Remuzzi, G; Tobe, SW; Toto, R1
Kang, WL; Xu, GS1
Allison, SJ1
Avramut, MC; Boels, MG; Dane, MJ; Gröne, HJ; Koster, AJ; Koudijs, A; Lee, DH; Rabelink, TJ; van den Berg, BM; van der Vlag, J; van Faassen, E; van Zonneveld, AJ1
Andress, D; Brennan, JJ; Coll, B; Correa-Rotter, R; Davis, JW; de Zeeuw, D; Heerspink, HJ; Idler, K; Kohan, DE; Liu, M; Makino, H; Parving, HH; Perkovic, V; Remuzzi, G; Tobe, SW; Toto, R1
Andress, DL; Audhya, P; Garimella, T; Kohan, DE; Molitch, M; Pritchett, Y; Wen, S1
Ritz, E; Wenzel, RR1
Andress, DL; Brennan, J; Coll, B; Kohan, DE; Molitch, M; Pritchett, Y1
Horio, T; Johnson, RJ; Kangawa, K; Kawano, Y; Suga, S; Yasui, N; Yoshihara, F1

Reviews

1 review(s) available for atrasentan and Albuminuria

ArticleYear
Efficacy and safety of endothelin receptor antagonists in type 2 diabetic kidney disease: A systematic review and meta-analysis of randomized controlled trials.
    Diabetic medicine : a journal of the British Diabetic Association, 2021, Volume: 38, Issue:1

    Topics: Albuminuria; Atrasentan; Bosentan; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelin Receptor Antagonists; Heart Failure; Humans; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic

2021

Trials

9 trial(s) available for atrasentan and Albuminuria

ArticleYear
Early Response in Albuminuria and Long-Term Kidney Protection during Treatment with an Endothelin Receptor Antagonist: A Prespecified Analysis from the SONAR Trial.
    Journal of the American Society of Nephrology : JASN, 2021, Volume: 32, Issue:11

    Topics: Aged; Albuminuria; Atrasentan; Causality; Creatinine; Diabetic Nephropathies; Double-Blind Method; Drug Therapy, Combination; Endothelin Receptor Antagonists; Female; Humans; Male; Middle Aged; Renal Insufficiency, Chronic; Risk Reduction Behavior; Sodium Potassium Chloride Symporter Inhibitors; Treatment Outcome

2021
The Effect of Atrasentan on Kidney and Heart Failure Outcomes by Baseline Albuminuria and Kidney Function: A
    Clinical journal of the American Society of Nephrology : CJASN, 2021, Volume: 16, Issue:12

    Topics: Albuminuria; Atrasentan; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Glomerular Filtration Rate; Heart Failure; Humans; Kidney; Renal Insufficiency; Renal Insufficiency, Chronic

2021
Inter-individual variability in atrasentan exposure partly explains variability in kidney protection and fluid retention responses: A post hoc analysis of the SONAR trial.
    Diabetes, obesity & metabolism, 2021, Volume: 23, Issue:2

    Topics: Albuminuria; Atrasentan; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Glomerular Filtration Rate; Humans; Kidney

2021
Determining the optimal dose of atrasentan by evaluating the exposure-response relationships of albuminuria and bodyweight.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:8

    Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atrasentan; Biological Variation, Population; Biomarkers; Body Weight; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Endothelin A Receptor Antagonists; Humans; Metabolic Clearance Rate; Renal Elimination; Renal Insufficiency; Severity of Illness Index; Sodium

2018
The endothelin antagonist atrasentan lowers residual albuminuria in patients with type 2 diabetic nephropathy.
    Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:5

    Topics: Aged; Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atrasentan; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Drug Therapy, Combination; Endothelin-1; Female; Humans; Kidney Function Tests; Lipids; Male; Middle Aged; Pyrrolidines

2014
Predictors of Atrasentan-Associated Fluid Retention and Change in Albuminuria in Patients with Diabetic Nephropathy.
    Clinical journal of the American Society of Nephrology : CJASN, 2015, Sep-04, Volume: 10, Issue:9

    Topics: Aged; Albuminuria; Atrasentan; Body Fluids; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Endothelin Receptor Antagonists; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Pyrrolidines; Weight Gain

2015
Comparison of exposure response relationship of atrasentan between North American and Asian populations.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:4

    Topics: Aged; Albuminuria; Asia; Asian People; Atrasentan; Bilirubin; Body Fluids; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelin Receptor Antagonists; Female; Humans; Male; Middle Aged; North America; Pyrrolidines; Treatment Outcome; Weight Gain; White People

2017
Addition of atrasentan to renin-angiotensin system blockade reduces albuminuria in diabetic nephropathy.
    Journal of the American Society of Nephrology : JASN, 2011, Volume: 22, Issue:4

    Topics: Aged; Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atrasentan; Diabetic Nephropathies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Endothelin A Receptor Antagonists; Female; Glomerular Filtration Rate; Humans; Incidence; Male; Middle Aged; Pyrrolidines; Renin-Angiotensin System; Treatment Outcome

2011
Clinical efficacy of the selective endothelin A receptor antagonist, atrasentan, in patients with diabetes and chronic kidney disease (CKD).
    Life sciences, 2012, Oct-15, Volume: 91, Issue:13-14

    Topics: Aged; Albuminuria; Atrasentan; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Edema; Endothelin A Receptor Antagonists; Female; Glomerular Filtration Rate; Hispanic or Latino; Humans; Male; Middle Aged; Pyrrolidines; Renal Insufficiency, Chronic; Renin-Angiotensin System

2012

Other Studies

8 other study(ies) available for atrasentan and Albuminuria

ArticleYear
Atrasentan: The Difficult Task of Integrating Endothelin A Receptor Antagonists into Current Treatment Paradigm for Diabetic Kidney Disease.
    Clinical journal of the American Society of Nephrology : CJASN, 2021, Volume: 16, Issue:12

    Topics: Albuminuria; Atrasentan; Diabetes Mellitus; Diabetic Nephropathies; Endothelin A Receptor Antagonists; Endothelin Receptor Antagonists; Endothelin-1; Humans; Pyrrolidines

2021
Relationship Between Atrasentan Concentrations and Urinary Albumin to Creatinine Ratio in Western and Japanese Patients With Diabetic Nephropathy.
    Clinical therapeutics, 2018, Volume: 40, Issue:2

    Topics: Aged; Albuminuria; Atrasentan; Body Weight; Clinical Trials, Phase II as Topic; Creatinine; Diabetic Nephropathies; Double-Blind Method; Edema; Female; Humans; Kidney Function Tests; Male; Middle Aged; Randomized Controlled Trials as Topic

2018
Number and frequency of albuminuria measurements in clinical trials in diabetic nephropathy.
    Clinical journal of the American Society of Nephrology : CJASN, 2015, Mar-06, Volume: 10, Issue:3

    Topics: Aged; Albuminuria; Amides; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atrasentan; Bone Density Conservation Agents; Diabetic Nephropathies; Endothelin Receptor Antagonists; Ergocalciferols; Female; Fumarates; Humans; Losartan; Male; Middle Aged; Office Visits; Pyrrolidines; Randomized Controlled Trials as Topic; Research Design; Statistics as Topic; Urine Specimen Collection

2015
Atrasentan increased the expression of klotho by mediating miR-199b-5p and prevented renal tubular injury in diabetic nephropathy.
    Scientific reports, 2016, Jan-27, Volume: 6

    Topics: 3' Untranslated Regions; Albuminuria; Animals; Antioxidants; Atrasentan; Biomarkers; Cell Line; Diabetic Nephropathies; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation; Glucuronidase; Humans; Kidney Function Tests; Kidney Tubules; Klotho Proteins; Male; Mice; MicroRNAs; Middle Aged; Mitochondria; Promoter Regions, Genetic; Pyrrolidines; RNA Interference

2016
Diabetic nephropathy: Atrasentan stabilizes the endothelial glycocalyx.
    Nature reviews. Nephrology, 2016, Volume: 12, Issue:6

    Topics: Albuminuria; Atrasentan; Diabetic Nephropathies; Endothelial Cells; Endothelium, Vascular; Glycocalyx; Humans; Pyrrolidines

2016
Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy.
    Diabetes, 2016, Volume: 65, Issue:8

    Topics: Albuminuria; Animals; Atrasentan; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endothelin Receptor Antagonists; Glomerular Filtration Rate; Kidney Glomerulus; Male; Mice; Mice, Knockout; Pyrrolidines

2016
Endothelin antagonist as add-on treatment for proteinuria in diabetic nephropathy: is there light at the end of the tunnel?
    Journal of the American Society of Nephrology : JASN, 2011, Volume: 22, Issue:4

    Topics: Albuminuria; Atrasentan; Diabetic Nephropathies; Endothelins; Glomerular Filtration Rate; Humans; Proteinuria; Pyridines; Pyrimidines; Pyrrolidines; Renin-Angiotensin System; Treatment Outcome

2011
Endothelin a receptor blockade and endothelin B receptor blockade improve hypokalemic nephropathy by different mechanisms.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:2

    Topics: Albuminuria; Animals; Atrasentan; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Hypertrophy; Hypokalemia; Kidney; Kidney Diseases; Kidney Tubules; Male; Potassium; Proteinuria; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B

2003