atractylodin has been researched along with Arthritis--Rheumatoid* in 1 studies
1 other study(ies) available for atractylodin and Arthritis--Rheumatoid
Article | Year |
---|---|
Atractylodin Suppresses Dendritic Cell Maturation and Ameliorates Collagen-Induced Arthritis in a Mouse Model.
The aim of this study was to evaluate the immunomodulatory effects of atractylodin, a polyethylene alkyne, on the maturation of bone marrow-derived dendritic cells (BM-DC) as well as its antirheumatic effect on collagen-induced arthritis (CIA) in DBA/1 mice. Our results indicate that atractylodin effectively suppressed the secretion of pro-inflammatory cytokines, expression of costimulatory molecules, and p38 MAPK, ERK, and NF-κBp65 signaling pathways in LPS-incubated dendritic cells (DCs). Additionally, the proliferation and cytokine secretion (IFN-γ and IL-17A) of CD8 Topics: Animals; Arthritis, Rheumatoid; Atractylodes; Cell Differentiation; Cell Proliferation; Collagen Type II; Dendritic Cells; Disease Models, Animal; Furans; Humans; Interferon-gamma; Interleukin-17; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Th17 Cells; Transcription Factor RelA | 2019 |