Page last updated: 2024-08-25

atovaquone and Malaria

atovaquone has been researched along with Malaria in 147 studies

*Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. [MeSH]

Research

Studies (147)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (1.36)	18.7374
1990's	11 (7.48)	18.2507
2000's	46 (31.29)	29.6817
2010's	72 (48.98)	24.3611
2020's	16 (10.88)	2.80

Authors

Authors	Studies
Alzeer, J; Chollet, J; Heinze-Krauss, I; Hubschwerlen, C; Matile, H; Ridley, RG	1
Batchelor, JF; Bueno, JM; Capon, EC; Cheesman, NJ; Chicharro, J; Fernández, E; Fiandor, JM; Fry, M; Gargallo-Viola, D; Gómez de las Heras, F; Herreros, E; Hudson, AT; León, ML; Pudney, M; Trimming, H; Woolven, J; Yeates, CL	1
Beck, HP; Brun, R; Cohen, SB; Dartois, V; Dharia, NV; Diagana, TT; Fidock, DA; Goh, A; González-Páez, GE; Jegla, T; Keller, TH; Lakshminarayana, SB; Lee, MC; McNamara, C; Nosten, F; Plouffe, DM; Renia, L; Rottmann, M; Russell, B; Schmitt, EK; Seitz, P; Spencer, KR; Suwanarusk, R; Tan, J; Winzeler, EA; Yeung, BK; Zou, B	1
Bathurst, I; Buckner, FS; Burrows, J; Charman, SA; Charman, WN; Creason, S; Deng, X; El Mazouni, F; Floyd, DM; Gujjar, R; Matthews, D; Phillips, MA; Rathod, PK; Shackleford, DM; White, J; White, KL	1
Lopes, F; Moreira, R; Mota, MM; Prudêncio, M; Rodrigues, T	1
Amewu, R; Berger, O; Berry, NG; Biagini, GA; Charoensutthivarakul, S; Fisher, NE; Gibbons, P; Hill, A; Hong, WD; Leung, SC; Mbekeani, A; Nixon, GL; O'Neill, PM; Pacorel, B; Pidathala, C; Sharma, R; Shone, AE; Srivastava, A; Stocks, PA; Taylor, L; Ward, SA; Warman, AJ	2
Clardy, J; Derbyshire, ER; Mota, MM; Prudêncio, M	1
Bronze, MR; da Cruz, FP; Gamo, FJ; Gonçalves, D; Gut, J; Lafuente-Monasterio, MJ; Lopes, F; Moreira, R; Mota, MM; Prudêncio, M; Ressurreição, AS; Rodrigues, T; Rosenthal, PJ; Schneider, G; Sitoe, AR	1
Albuquerque, IS; Bronze, MR; Gonçalves, LM; Guedes, RC; Gut, J; Lopes, F; Meireles, P; Moreira, R; O'Neill, PM; Oliveira, R; Pires, E; Prudêncio, M; Rosenthal, PJ	1
Achar, V; Angulo-Barturen, I; Avery, VM; Awasthy, D; Bharath, S; Coburn-Flynn, O; Duffy, S; Ferrer, S; Fidock, DA; Gamo, FJ; Hameed P, S; Hosagrahara, V; Iyer, PS; Jiménez-Díaz, MB; Kavanagh, S; Lee, MC; Martínez, MS; Menasinakai, S; Morayya, S; Nanduri, R; Narayanan, S; Panduga, V; Prabhakar, KR; Raichurkar, A; Ramachandran, S; Rautela, N; Reddy, J; Sambandamurthy, VK; Sanz, LM; Saralaya, R; Shanbhag, G; Srivastava, A; Waterson, D	1
Bathurst, I; Burrows, JN; Charman, SA; Cross, RM; Flanigan, DL; Fronczek, FR; Guida, WC; Kyle, DE; LaCrue, AN; Maignan, JR; Manetsch, R; Monastyrskyi, A; Mutka, TS; Sáenz, FE; Shackleford, DM; White, KL; Wojtas, L	1
Azas, N; Basmaciyan, L; Cohen, A; Crozet, MD; Dallemagne, P; Deharo, E; Dumètre, A; Hutter, S; Laget, M; Lancelot, JC; Lesnard, A; Lorthiois, A; Mazier, D; Paloque, L; Rathelot, P; Rault, S; Sibley, CH; Suzanne, P; Valentin, A; Vanelle, P; Verhaeghe, P	1
Angulo-Barturen, Í; Bahamontes-Rosa, N; Ballell-Pages, L; Berry, NG; Biagini, GA; Blackman, MJ; Calderón, F; Castañeda, P; Crespo, B; de Cózar, C; de Mercado, J; Fernández, J; Frigerio, M; Guijarro, L; Jiménez-Díaz, MB; Martínez-Martínez, MS; McConville, M; Nixon, GL; O'Neill, PM; Santos-Villarejo, Á; Sanz, LM; Ward, SA; Washbourn, G	1
Coelho, L; Lukens, AK; Mazitschek, R; Moreira, R; Nogueira, F; Paulo, A; Santos, SA; Wirth, DF	1
Calderón, F; Fernández-Álvaro, E; Hong, WD; Nixon, GL; O'Neill, PM	1
Barnard, L; Birkholtz, LM; Botha, M; Brunschwig, C; Burrows, JN; Chibale, K; Churchyard, A; Coetzer, TL; Denti, P; Egan, TJ; Laing, L; Lauterbach, S; Machado, M; Ndubi, F; Njogu, PM; Njoroge, M; Nondaba, S; Okombo, J; Prudêncio, M; Reader, J; Singh, K; Wiesner, L; Wilkinson, C; Wittlin, S; Yeates, C	1
Berry, P; Campo, B; Cao, J; Ciaravino, V; Easom, EE; Erve, JCL; Freund, YR; Gamo, FJ; Guo, D; Jacobs, RT; Plattner, JJ; Rosenthal, PJ; Sanz, LM; Zhang, YK	1
Avery, VM; Buchholz, M; Delves, MJ; Duffy, S; Fischli, C; Held, J; Knaab, TC; Kuna, K; Kurz, T; Lehmann, U; Leven, M; Lungerich, B; Meister, S; Meitzner, D; Mordmüller, B; Stahlke, P; Winzeler, EA; Wittlin, S	1
Bane, CE; Black, C; Butler, K; Caridha, D; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Huezo, SJ; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Nolan, C; Olmeda, R; Potter, B; Pou, S; Rasmussen, SA; Read, L; Riscoe, MK; Roncal, N; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Stephens, MT; Tan, JC; Vesely, B; Vuong, C; Winter, RW; Xie, L; Zeng, Q; Zhang, J; Zhang, P	1
Cheong, SL; Ng, CH; Tibon, NS	1
Bane, CE; Bayles, BR; Black, C; Butler, K; Caridha, D; Ceja, FG; Cooper, RA; Dodean, RA; Gaona, H; Gaynor-Ohnstad, L; Kancharla, P; Kelly, JX; Kreishman-Deitrick, M; Leed, SE; Li, Q; Li, Y; Lin, H; Luong, TL; Marcsisin, S; Melendez, V; Mu, J; Nolan, C; Olmeda, R; Potter, B; Pou, S; Pybus, B; Rasmussen, SA; Read, L; Reynolds, KA; Riscoe, MK; Roncal, N; Rosenthal, PJ; Sciotti, RJ; Smilkstein, MJ; Sousa, J; Tumwebaze, PK; Vesely, B; Vuong, C; Xie, L; Zeng, Q; Zhang, J; Zhang, P	1
Asakawa, AH; Brockmeyer, F; Casandra, D; Huang, L; Kyle, DE; LaCrue, AN; Maher, SP; Maignan, JR; Manetsch, R; Mashkouri, S; Monastyrskyi, A; Padin-Irizarry, V; Parvatkar, PT; Sakhno, YI; Zhao, Y	1
Abdel-Daim, MM; Alkhoudary, MS; Alsharif, KF; El-Sayed, SAE; Igarashi, I; Rizk, MA	1
Adams, KL; Bopp, S; Catteruccia, F; Dabiré, RK; Diabaté, A; Hien, DFS; Lefèvre, T; Ma, E; Paré, PSL; Paton, DG; Probst, AS; Shaw, WR; Singh, N; Volkman, SK; Wirth, DF; Yerbanga, RS	1
Boelle, PY; Jauréguiberry, S; Kendjo, E; Le Goff, M; Piarroux, R; Thellier, M	1
Ahiya, AI; Lamb, IM; Lindner, SE; Mather, MW; Mell, JC; Morrisey, J; Rios, KT; Shukla, A; Vaidya, AB	1
Baghdadi, HB; El-Sayed, SAE; Eltaysh, R; Igarashi, I; Rizk, MA	1
Addo, M; Heitkamp, C; Jochum, J; Kreuels, B; Krumkamp, R; Landsmann, L; Moehlmann, MW; Radt, C; Ramharter, M; Reinsberg, F; Rothe, C; Vinnemeier, C	1
Arun Kumar, K; Bhattacharyya, MK; Bhattacharyya, S; Dey, S; Fangaria, N; Padhi, S; Roy, A; Singh, P; Tabassum, W	1
Bakshi, RP; Balta, VA; Canonizado, MA; Dziedzic, AG; Elahi, R; Jedlicka, AE; Mann, A; Mlambo, G; Nenortas, E; Owen, A; Prigge, ST; Romero-Rodriguez, K; Sayeed, A; Shapiro, TA; Sinnis, P; Stiffler, D; Sullivan, DJ; Tripathi, AK	1
Arsuaga, M; Barreiro, P; de la Calle, F; de Miguel, R; Diaz, M; Loli-Ausejo, D; Tarin, EJ; Trigo, E	1
Brett-Major, D; Fraser, J; Hickey, PW; Mitra, I; Riddle, MS; Tribble, DR	1
Almeida, FG; Azevedo, MF; Buriticá, NL; Crispim, M; Katzin, AM; Kimura, EA; Melo, HR; Sussmann, RAC; Verdaguer, IB; Zafra, CA	1
Abla, N; Chalon, S; Chughlay, MF; Haouala, A; Hutter, B; Lorch, U; Macintyre, F; Marie Tchouatieu, A	1
Angarano, G; Castelli, F; Dell'Acqua, R; Di Gennaro, F; Fabrizio, C; L'Episcopia, M; Lo Caputo, S; Menegon, M; Monno, L; Saracino, A; Severini, C	1
Akkouche, W; Barzon, L; Biasolo, MA; De Canale, E; Marini, G; Masiero, S; Menegotto, N; Palù, G; Sgarabotto, D	1
Alagusundaramoorthy, SS; Jacob, A; Selvarajan, D; Sundaravel, S	1
Arguin, PM; Mace, KE; Minta, AA; Tan, KR	1
Darade, A; Pathak, S; Patravale, V; Sharma, S	1
Hai, F; Islam, S	1
Bakshi, RP; Ippolito, MM; Mlambo, G; Nenortas, E; Owen, A; Rannard, SP; Savage, AC; Shapiro, TA; Tatham, LM; Tripathi, AK	1
Crum-Cianflone, NF; Edwards, R; Khattar, R	1
Arsuaga, M; Dinkessa, AW; González, LM; Gray, J; Montero, E; Padial, ES; Puente, S; Sevilla, E; Trigo, E	1
Furuya-Kanamori, L; Lau, CL; Mills, DJ; Mills, LC; Ramsey, L	1
Meltzer, E; Schwartz, E	1
Gutman, JR; Mayer, RC; Tan, KR	1
Biber, A; Harel, R; Schwartz, E	1
Gerstenlauer, C	1
Cowell, AN; Winzeler, EA	1
Garrido Jareño, M; Otero Reigada, MDC; Peman García, J; Ramírez Cuentas, JH; Roselló Guijarro, M; Urtasun Erburu, A	1
Baier, M; Eisermann, P; Hagel, S; Reuken, PA; Rödel, J; Stallmach, A	1
Angulo-Barturen, I; Avery, VM; Bathurst, I; Burrows, JN; Charman, SA; Cross, RM; Delves, MJ; Duffy, S; Ferrer, S; Forquer, IP; Gamo, FJ; Guy, RK; Herreros, E; Jiménez-Díaz, MB; Kelly, JX; Kocken, CHM; Kyle, DE; LaCrue, AN; Li, Y; Manetsch, R; Marfurt, J; Mather, MW; Morrisey, JM; Mutka, T; Nilsen, A; Noviyanti, R; Price, RN; Riscoe, MK; Ryan, E; Saenz, FE; Sanz, LM; Sebayang, BF; Shackleford, DM; Siegl, P; Sinden, RE; Steuten, J; Vaidya, AB; White, KL; Winter, RW; Wirjanata, G; Zeeman, AM	1
Kain, KC	2
Dickins, M; Gutteridge, W; Pudney, M; Woolley, JL; Zeman, A	1
Beerahee, M	1
Heisler, MH; Oyediran, AB	1
Blagborough, AM; Churcher, TS; Gething, PW; Ghani, AC; Sinden, RE; Upton, LM	1
Alemayehu, S; Coggeshall, P; Cohen, R; Feghali, K; Hang, J; Kamau, E; Komisar, J; Weina, PJ; Zapor, M	1
Borhade, V; Pathak, S; Patravale, V; Sharma, S	1
Ehrhardt, J; Frank, M; Kremsner, P; Trein, A	1
Burchard, GD	2
Amelot, A; Dupouy-Camet, J; Jeanmougin, M	1
Berman, J; DiTusa, C; Gettayacamin, M; Im-erbsin, R; Kozar, MP; Ohrt, C; Pybus, B; Sousa, J; Tungtaeng, A	1
Arguin, PM; Landman, KZ; Tan, KR	1
Andrews, KT; Beattie, KD; Blundell, S; Campbell, A; Charman, SA; Coster, MJ; Davis, RA; Edstein, MD; Healy, PC; Koltun, M; MacKenzie, D; Pouwer, RH; Quinn, RJ; Schwartz, BD; Skinner-Adams, TS	1
Bhardwaj, J; Goyal, M; Prakash, K; Puri, SK; Siddiqui, AJ; Soni, A; Tiwari, V	1
Hoepelman, AI; Marzuki, S; Nuralitha, S; Roelands, J; Siregar, JE; Syafruddin, D; Verhoef, J	1
Borhade, V; Deshpande, V; Gokarna, V; Kate, L; Pathak, S; Patravale, V; Prabhu, P; Sharma, S	1
Cozijnsen, A; Goodman, CD; Jacobs-Lorena, M; Kita, K; Marzuki, S; Matsuoka, H; Matsuzaki, M; McFadden, GI; Mollard, V; Siregar, JE; Sturm, A; Syafruddin, D; Toyama, T; Vega-Rodríguez, J	1
Howlett-Shipley, R; Quantick, O; Ross, D; Roughton, S	1
Bar-Meir, M; Eisenberg, N; Lachish, T; Schwartz, E	1
Shanks, D	1
Buchanan, HD; Goodman, CD; McFadden, GI	1
Hoepelman, AIM; Marzuki, S; Murdiyarso, LS; Nuralitha, S; Roelands, J; Siregar, JE; Syafruddin, D; Verhoef, J	1
Andersson, H; Askling, HH; Falck, B; Rombo, L	1
Covian, R; Gribble, GW; Hughes, LM; Trumpower, BL	1
Afonso, A; Alves, AC; Castro, H; Lopes, D; Neto, Z; Rosário, VD; Tomás, AM	1
Balu, L; Chevret, L; Habes, D; Orostegui, L; Pussard, E	1
Hyde, JE; Müller, IB	1
Hviid, A; Pasternak, B	1
Bellagamba, R; D'Avolio, A; Gallo, AL; Ivanovic, J; Narciso, P; Nicastri, E; Pucillo, LP; Tempestilli, M; Tommasi, C	1
Ensom, MH; Wilby, KJ	1
Bozzo, P; Einarson, A; Irvine, MH	1
Arguin, PM; Magill, AJ; Steinhardt, LC	1
Buchholz, K; da Cruz, FP; Gamo, FJ; Hannus, M; Lafuente-Monasterio, MJ; Marti, M; Martin, C; Moreira, R; Mota, MM; Prudêncio, M; Rodrigues, T; Sönnichsen, B	1
Fadden, SJ; Keene, DD; Roughton, S; Tong, JL	1
Petersen, E; Schlagenhauf, P	1
Bartoloni, A; Beltrame, A; Bouchaud, O; Calleri, G; Clerinx, J; Gautret, P; Grobusch, MP; Jelinek, T; Kaiser, A; Kern, P; Kremsner, PG; Matteelli, A; Méchaï, F; Mühlberger, N; Parola, P; Peyerl-Hoffmann, G; Probst, M; Schmid, ML; Weinke, T	1
Amano, K; Ide, D; Kato, T; Okuda, J; Takei, Y; Yamaguchi, Y	1
Dzinjalamala, FK; Laufer, MK; Laurens, MB; Masonga, R; Nyirenda, OM; Plowe, CV; Stokes-Riner, A; Taylor, TE; Thesing, PC	1
Basco, LK; Delmont, J; Moyou-Somo, R; Ngane Foumane, V; Sayang, C; Soula, G; Tahar, R	1
Chiodini, P; Evans, M; Morgan, GS	1
Biagini, GA; Fisher, N; Lalloo, DG; Moss, DM; Nixon, GL; O'Neill, PM; Shone, AE; Ward, SA	1
Jong, EC; Nothdurft, HD	1
Ditters, JM; Ligthelm, RJ; Overbosch, D; Stricker, BH; Sturkenboom, MC; van Riemsdijk, MM	1
Binder, R; Faucher, JF; Gruss, H; Kremsner, PG; Lell, B; Matsiegui, PB; Miller, GB; Missinou, MA; Neubauer, R; Que, JU	1
Kager, PA	1
Petersen, E	1
Overbosch, D	1
Tracey, C	1
Fischer, PR; Stauffer, W	1
Jomaa, H; Ortmann, R; Schlitzer, M; Wiesner, J	1
Chambers, JA	1
Jones, ME; Lessells, R; Welsby, PD	1
Camus, D; De Boever, EH; Djossou, F; Dutoit, E; Hedgley, C; Høgh, B; Malvy, D; Miller, GB; Roskell, NS; Schilthuis, HJ	1
Stingl, P	1
Croft, AM	4
Green, AD; Roberts, KI; Tuck, JJ	1
Ha, KH; Hill, P; Kessl, JJ; Lange, BB; Merritt, AK; Meshnick, SR; Meunier, B; Trumpower, BL	1
Beer, MD; Croft, AM; Herxheimer, A	1
Kurtzhals, JA; Vestergaard, LS	1
Kurtzhals, JA	1
Berman, J; Duparc, S; Gutierrez, P; Luzz, M; Soto, J; Toledo, J	1
Callen, EC; Church, CO	1
Chollet, J; Santo-Tomas, J; Scheurer, C; Snyder, C; Wittlin, S	1
Le Bras, J; Loiseau, PM	1
Hyde, JE	1
Hunter, PR; Nakato, H; Vivancos, R	1
Durrheim, DN; Massey, P; Speare, R	1
D'Acremont, V; Genton, B; Landry, P; Senn, N	1
Kita, K; Marzuki, S; Matsuoka, H; Siregar, JE; Syafruddin, D	1
Berry, N; Biagini, GA; Bonar-Law, R; Bray, PG; Fisher, N; Meunier, B; O'Neill, PM; Owen, A; Stocks, PA; Ward, SA; Williams, DP	1
Atlan, A; Gallien, S; Lagrange-Xelot, M; Molina, JM; Sarfati, C; Schlemmer, F; Taieb, F	1
Christopherson, RI; Lyons, SD; Phillips, L; Rieckmann, KH; Seymour, KK	1
Billingsley, PF; Fowler, RE; Pudney, M; Sinden, RE	1
Alves, FP; Boulos, M; Cerutti, C; de Alencar, FE; Durlacher, RR; Milhous, W; Pang, LW	1
Bloland, PB; Doumbo, OK; Kazembe, PN; Nwanyanwu, OC; Ruebush, TK; Watkins, WM	1
Kremsner, PG; Lell, B; Luckner, D; Ndjavé, M; Scott, T	1
Davis, TM	1
Whitty, CJ	1
Butcher, GA; Mendoza, J; Sinden, RE	1
Croft, A; Geary, K; Morgan, L	1
Beck, B; Blum, J; Funk, M; Furrer, H; Genton, B; Hatz, FR; Holzer, B; Loutan, L; Markwalder, K; Raeber, PA; Schlagenhauf, P; Siegl, G; Steffen, R; Stürchler, D; Wyss, R	1
Behrens, RH; Bienzle, U; Chulay, JD; Clarke, PD; Kain, KC; Knobloch, J; Nothdurft, HD; Overbosch, D; Roskell, NS; Schilthuis, H; Shaw, D; Toovey, S	1
Davies, CS; Matthews, PJ; Pudney, M; Sinden, RE	1
Gutteridge, WE	1

Reviews

28 review(s) available for atovaquone and Malaria

Article	Year
Targeting the liver stage of malaria parasites: a yet unmet goal. Journal of medicinal chemistry, 2012, Feb-09, Volume: 55, Issue:3 Topics: Animals; Antimalarials; Humans; Life Cycle Stages; Liver; Malaria; Plasmodium; Structure-Activity Relationship	2012
Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action. Journal of medicinal chemistry, 2016, 06-23, Volume: 59, Issue:12 Topics: Antimalarials; Biological Products; Chemistry, Pharmaceutical; Humans; Malaria; Molecular Structure	2016
Current progress in antimalarial pharmacotherapy and multi-target drug discovery. European journal of medicinal chemistry, 2020, Feb-15, Volume: 188 Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines	2020
Recognition and Management of Malaria. The Nursing clinics of North America, 2019, Volume: 54, Issue:2 Topics: Antimalarials; Atovaquone; Drug Combinations; Ghana; Humans; Malaria; Male; Middle Aged; Practice Guidelines as Topic; Proguanil; Risk Factors; Severity of Illness Index; Travel-Related Illness; Treatment Outcome; United States	2019
The genomic architecture of antimalarial drug resistance. Briefings in functional genomics, 2019, 09-24, Volume: 18, Issue:5 Topics: Aminoquinolines; Anti-Bacterial Agents; Antimalarials; Artemisinins; Atovaquone; Drug Resistance; Drug Resistance, Multiple; Folic Acid Antagonists; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Quinine	2019
Expanded table: drugs for prophylaxis of malaria. The Medical letter on drugs and therapeutics, 2019, Jul-01, Volume: 61, Issue:1575 Topics: Aminoquinolines; Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria; Pre-Exposure Prophylaxis; Statistics as Topic; Travel	2019
Atovaquone and proguanil hydrochloride: a review of nonclinical studies. Journal of travel medicine, 1999, Volume: 6 Suppl 1 Topics: Animals; Antimalarials; Atovaquone; Chemoprevention; Disease Outbreaks; Dogs; Drug Combinations; Humans; Malaria; Mice; Models, Animal; Plasmodium falciparum; Plasmodium malariae; Proguanil; Rats; Travel	1999
Clinical pharmacology of atovaquone and proguanil hydrochloride. Journal of travel medicine, 1999, Volume: 6 Suppl 1 Topics: Animals; Antimalarials; Atovaquone; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Activation; Humans; Intestinal Absorption; Intestinal Mucosa; Lymphocytes; Malaria; Malaria, Falciparum; Malaria, Vivax; Proguanil	1999
Is the Mitochondrion a Good Malaria Drug Target? Trends in parasitology, 2017, Volume: 33, Issue:3 Topics: Antimalarials; Atovaquone; Drug Delivery Systems; Drug Resistance; Humans; Malaria; Mitochondria; Plasmodium falciparum	2017
Antimalarial drugs: modes of action and mechanisms of parasite resistance. Future microbiology, 2010, Volume: 5, Issue:12 Topics: Antimalarials; Artemisinins; Atovaquone; Drug Resistance; Folic Acid Antagonists; Humans; Malaria; Plasmodium falciparum; Quinolines	2010
Pharmacokinetics of antimalarials in pregnancy: a systematic review. Clinical pharmacokinetics, 2011, Nov-01, Volume: 50, Issue:11 Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Sulfadoxine	2011
Review: Malaria chemoprophylaxis for travelers to Latin America. The American journal of tropical medicine and hygiene, 2011, Volume: 85, Issue:6 Topics: Antimalarials; Atovaquone; Drug Combinations; Drug Therapy, Combination; Humans; Latin America; Malaria; Malaria, Vivax; Plasmodium vivax; Primaquine; Proguanil; Travel	2011
Antimalarial pharmacology and therapeutics of atovaquone. The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:5 Topics: Antimalarials; Atovaquone; Chemoprevention; Drug Combinations; Humans; Malaria; Proguanil; United States	2013
Current drugs for antimalarial chemoprophylaxis: a review of efficacy and safety. Journal of travel medicine, 2001, Volume: 8, Issue:Suppl 3 Topics: Antimalarials; Atovaquone; Chloroquine; Doxycycline; Humans; Malaria; Mefloquine; Naphthoquinones; Primaquine; Proguanil	2001
[Three newly registered drugs in the Netherlands for the treatment and chemoprophylaxis of malaria: atovaquone-proguanil, artemether-lumefantrine and artemotil]. Nederlands tijdschrift voor geneeskunde, 2003, Feb-15, Volume: 147, Issue:7 Topics: Antimalarials; Artemether; Artemisinins; Atovaquone; Drug Approval; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria; Naphthoquinones; Netherlands; Proguanil; Sesquiterpenes; Treatment Outcome	2003
Atovaquone/proguanil: the need for family protection. Journal of travel medicine, 2003, Volume: 10 Suppl 1 Topics: Adult; Africa South of the Sahara; Aged; Antimalarials; Atovaquone; Child; Drug Combinations; Drug Resistance; Family; Humans; Malaria; Naphthoquinones; New Guinea; Proguanil; Randomized Controlled Trials as Topic; Travel; United States	2003
New antimalarial drugs. Angewandte Chemie (International ed. in English), 2003, Nov-10, Volume: 42, Issue:43 Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Design; Drug Resistance; Ethanolamines; Flavonoids; Fluorenes; Fosfomycin; Global Health; Humans; Lumefantrine; Malaria; Naphthoquinones; Naphthyridines; Plasmodium falciparum; Proguanil; Sesquiterpenes	2003
Military aviators, special operations forces, and causal malaria prophylaxis. Military medicine, 2003, Volume: 168, Issue:12 Topics: Aminoquinolines; Antimalarials; Atovaquone; Aviation; Chloroquine; Doxycycline; Drug Combinations; Humans; Malaria; Mefloquine; Military Personnel; Naphthoquinones; Primaquine; Proguanil; United States	2003
[Malaria: prophylaxis, treatment, stand-by medication. A single mosquito bite suffices]. MMW Fortschritte der Medizin, 2004, Jun-17, Volume: 146, Issue:25 Topics: Adult; Antimalarials; Artemether; Artemisinins; Atovaquone; Chloroquine; Climate; Doxycycline; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Male; Mefloquine; Naphthoquinones; Pregnancy; Proguanil; Risk Factors; Self Medication; Sesquiterpenes; Time Factors; Travel	2004
Malaria: prevention in travellers. Clinical evidence, 2003, Issue:10 Topics: Adult; Antimalarials; Atovaquone; Child; Chloroquine; Doxycycline; Female; Humans; Insect Repellents; Insecticides; Malaria; Mefloquine; Mosquito Control; Naphthoquinones; Pregnancy; Proguanil; Travel	2003
Malaria: prevention in travellers. Clinical evidence, 2004, Issue:11 Topics: Adult; Antimalarials; Atovaquone; Child; Chloroquine; Clothing; Doxycycline; Female; Humans; Insect Repellents; Insecticides; Malaria; Mefloquine; Mosquito Control; Naphthoquinones; Pregnancy; Proguanil; Travel	2004
Malaria: prevention in travellers. Clinical evidence, 2004, Issue:12 Topics: Adult; Antimalarials; Atovaquone; Child; Chloroquine; Clothing; Doxycycline; Female; Humans; Insect Repellents; Insecticides; Malaria; Mefloquine; Mosquito Control; Naphthoquinones; Pregnancy; Travel	2004
Malaria: prevention in travellers. Clinical evidence, 2005, Issue:14 Topics: Adult; Antimalarials; Atovaquone; Child; Clothing; Doxycycline; Female; Humans; Insect Repellents; Insecticides; Malaria; Mefloquine; Mosquito Control; Naphthoquinones; Pregnancy; Proguanil; Travel	2005
[New drugs against parasitic diseases]. La Revue du praticien, 2007, Jan-31, Volume: 57, Issue:2 Topics: Antimalarials; Atovaquone; Humans; Malaria; Parasitic Diseases	2007
Drug-resistant malaria - an insight. The FEBS journal, 2007, Volume: 274, Issue:18 Topics: Animals; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Resistance; Folic Acid Antagonists; Humans; Malaria	2007
A systematic review and meta-analysis of the effectiveness and safety of atovaquone proguanil (Malarone) for chemoprophylaxis against malaria. The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:5 Topics: Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria; Proguanil	2007
[Malaria--chemoprophylaxis 2001]. Therapeutische Umschau. Revue therapeutique, 2001, Volume: 58, Issue:6 Topics: Africa; Antimalarials; Asia; Atovaquone; Chloroquine; Contraindications; Doxycycline; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Mefloquine; Naphthoquinones; Practice Guidelines as Topic; Proguanil; South America; Switzerland; Travel	2001
Antimalarial drugs currently in development. Journal of the Royal Society of Medicine, 1989, Volume: 82 Suppl 17 Topics: Aminoquinolines; Antimalarials; Artemisinins; Atovaquone; Chemical Phenomena; Chemistry; Drug Design; Drug Evaluation, Preclinical; Drug Resistance; Humans; Malaria; Naphthoquinones; Research; Sesquiterpenes	1989

Trials

10 trial(s) available for atovaquone and Malaria

Article	Year
Unanticipated CNS Safety Signal in a Placebo-Controlled, Randomized Trial of Co-Administered Atovaquone-Proguanil and Amodiaquine. Clinical pharmacology and therapeutics, 2022, Volume: 111, Issue:4 Topics: Amodiaquine; Antimalarials; Atovaquone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Falciparum; Male; Proguanil; Treatment Outcome	2022
Drug-free Holidays: Compliance, Tolerability, and Acceptability of a 3-Day Atovaquone/Proguanil Schedule for Pretravel Malaria Chemoprophylaxis in Australian Travelers. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 06-18, Volume: 69, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antimalarials; Atovaquone; Australia; Chemoprevention; Drug Administration Schedule; Drug Combinations; Drug Tolerance; Female; Holidays; Humans; Malaria; Male; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Proguanil; Surveys and Questionnaires; Travel; Travel Medicine; Young Adult	2019
A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria. PloS one, 2012, Volume: 7, Issue:8 Topics: Antimalarials; Artemisinins; Artesunate; Atovaquone; Azithromycin; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Endpoint Determination; Female; Genotyping Techniques; Humans; Infant; Longitudinal Studies; Malaria; Male; Proguanil	2012
Atovaquone plus chloroguanide versus mefloquine for malaria prophylaxis: a focus on neuropsychiatric adverse events. Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:3 Topics: Adolescent; Adult; Affect; Antimalarials; Atovaquone; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Malaria; Male; Mefloquine; Naphthoquinones; Proguanil; Prospective Studies; Sex Factors	2002
Efficacy of atovaquone/proguanil for malaria prophylaxis in children and its effect on the immunogenicity of live oral typhoid and cholera vaccines. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Nov-15, Volume: 35, Issue:10 Topics: Administration, Oral; Adolescent; Antimalarials; Atovaquone; Chemoprevention; Child; Child, Preschool; Cholera Vaccines; Double-Blind Method; Female; Humans; Immunity; Malaria; Male; Naphthoquinones; Proguanil; Treatment Outcome; Typhoid-Paratyphoid Vaccines	2002
Atovaquone-proguanil versus chloroquine-proguanil for malaria prophylaxis in nonimmune pediatric travelers: results of an international, randomized, open-label study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Jun-15, Volume: 38, Issue:12 Topics: Adolescent; Antimalarials; Atovaquone; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Humans; Infant; Malaria; Naphthoquinones; Patient Compliance; Proguanil; Travel	2004
Randomized, double-blind, placebo-controlled study of Malarone for malaria prophylaxis in non-immune Colombian soldiers. The American journal of tropical medicine and hygiene, 2006, Volume: 75, Issue:3 Topics: Adolescent; Adult; Antimalarials; Atovaquone; Colombia; Double-Blind Method; Drug Combinations; Humans; Malaria; Male; Military Personnel; Naphthoquinones; Placebos; Proguanil	2006
Atovaquone and proguanil for the treatment of malaria in Brazil. The Journal of infectious diseases, 1997, Volume: 175, Issue:6 Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Brazil; Drug Therapy, Combination; Humans; Malaria; Male; Middle Aged; Naphthoquinones; Proguanil; Quinine; Tetracycline	1997
Randomised placebo-controlled study of atovaquone plus proguanil for malaria prophylaxis in children. Lancet (London, England), 1998, Mar-07, Volume: 351, Issue:9104 Topics: Adolescent; Antimalarials; Atovaquone; Child; Child, Preschool; Cohort Studies; Double-Blind Method; Drug Therapy, Combination; Humans; Malaria; Naphthoquinones; Proguanil	1998
Atovaquone-proguanil versus mefloquine for malaria prophylaxis in nonimmune travelers: results from a randomized, double-blind study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Oct-01, Volume: 33, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Atovaquone; Child; Child, Preschool; Double-Blind Method; Drug Combinations; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Naphthoquinones; Proguanil; Travel; Treatment Outcome	2001

Other Studies

109 other study(ies) available for atovaquone and Malaria

Article	Year
Phenyl beta-methoxyacrylates: a new antimalarial pharmacophore. Journal of medicinal chemistry, 2000, Feb-24, Volume: 43, Issue:4 Topics: Acrylates; Administration, Cutaneous; Administration, Oral; Animals; Antimalarials; Benzene Derivatives; Erythrocytes; In Vitro Techniques; Malaria; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship	2000
Synthesis and structure-activity relationships of 4-pyridones as potential antimalarials. Journal of medicinal chemistry, 2008, May-08, Volume: 51, Issue:9 Topics: Animals; Antimalarials; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Plasmodium yoelii; Pyridones; Structure-Activity Relationship	2008
Spiroindolones, a potent compound class for the treatment of malaria. Science (New York, N.Y.), 2010, Sep-03, Volume: 329, Issue:5996 Topics: Adenosine Triphosphatases; Animals; Antimalarials; Cell Line; Drug Discovery; Drug Resistance; Erythrocytes; Female; Genes, Protozoan; Humans; Indoles; Malaria; Male; Mice; Models, Molecular; Mutant Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Plasmodium vivax; Protein Synthesis Inhibitors; Protozoan Proteins; Rats; Rats, Wistar; Spiro Compounds	2010
Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice. Journal of medicinal chemistry, 2011, Jun-09, Volume: 54, Issue:11 Topics: Animals; Antimalarials; Dihydroorotate Dehydrogenase; Disease Models, Animal; Drug Design; Drug Discovery; Enzyme Inhibitors; Humans; Malaria; Mice; Microsomes, Liver; Molecular Structure; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium berghei; Plasmodium falciparum; Protein Binding; Pyrimidines; Solubility; Structure-Activity Relationship; Triazoles	2011
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2). Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5 Topics: Administration, Oral; Animals; Antimalarials; Crystallography, X-Ray; Drug Design; Electron Transport Complex III; Humans; In Vitro Techniques; Malaria; Male; Mice; Microsomes, Liver; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolones; Quinone Reductases; Structure-Activity Relationship	2012
Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2). Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5 Topics: Administration, Oral; Animals; Antimalarials; Atovaquone; Crystallography, X-Ray; Cytochromes b; Drug Design; Drug Resistance; Humans; Malaria; Male; Mice; Microsomes, Liver; Models, Molecular; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyridines; Quinolones; Quinone Reductases; Rats; Structure-Activity Relationship	2012
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. Proceedings of the National Academy of Sciences of the United States of America, 2012, May-29, Volume: 109, Issue:22 Topics: Animals; Anopheles; Antimalarials; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Inhibitory Concentration 50; Insect Vectors; Life Cycle Stages; Liver; Malaria; Malaria, Falciparum; Male; Mice; Mice, Inbred C57BL; Plasmodium berghei; Plasmodium falciparum; Treatment Outcome	2012
Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria. Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11 Topics: Antimalarials; Cell Line, Tumor; Humans; Imines; Liver; Malaria; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Quinolines; Structure-Activity Relationship	2013
Tetraoxane-pyrimidine nitrile hybrids as dual stage antimalarials. Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11 Topics: Animals; Antimalarials; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Malaria; Mice, Inbred C57BL; Molecular Docking Simulation; Nitriles; Oxidative Stress; Peptidomimetics; Plasmodium berghei; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship; Tetraoxanes	2014
N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds. Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15 Topics: Aminopyridines; Animals; Antimalarials; Benzimidazoles; Hepatocytes; Humans; Malaria; Mice, SCID; Microsomes, Liver; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship	2014
Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium. Journal of medicinal chemistry, 2014, Nov-13, Volume: 57, Issue:21 Topics: Animals; Antimalarials; Humans; Inhibitory Concentration 50; Malaria; Mice; Microsomes, Liver; Parasitemia; Plasmodium; Plasmodium berghei; Quinolones; Structure-Activity Relationship	2014
Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium. European journal of medicinal chemistry, 2015, May-05, Volume: 95 Topics: Animals; Antimalarials; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Drug Discovery; Erythrocytes; Hep G2 Cells; Humans; Liver; Malaria; Male; Mice; Parasitemia; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship; Trophozoites	2015
Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials. Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16 Topics: Animals; Antimalarials; High-Throughput Screening Assays; Humans; In Vitro Techniques; Malaria; Malaria, Falciparum; Mice; Mice, SCID; Microsomes, Liver; Plasmodium berghei; Plasmodium falciparum; Serine Proteinase Inhibitors; Structure-Activity Relationship; Triazoles	2015
Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype. European journal of medicinal chemistry, 2015, Sep-18, Volume: 102 Topics: Antimalarials; Cell Survival; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Indoles; Malaria; Molecular Structure; Niacinamide; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2015
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model. Journal of medicinal chemistry, 2017, 02-23, Volume: 60, Issue:4 Topics: Animals; Antimalarials; Benzimidazoles; Life Cycle Stages; Malaria; Male; Mice; Plasmodium berghei; Structure-Activity Relationship	2017
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate. Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13 Topics: Amides; Animals; Antimalarials; Boron Compounds; Dogs; Female; Humans; Malaria; Malaria, Falciparum; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	2017
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14 Topics: Amides; Animals; Antimalarials; Hep G2 Cells; Humans; Hydrazones; Malaria; Mice; Phenanthrenes; Plasmodium berghei; Stereoisomerism; Structure-Activity Relationship	2017
Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials. Journal of medicinal chemistry, 2019, 04-11, Volume: 62, Issue:7 Topics: Acridones; Animals; Antimalarials; Disease Models, Animal; Drug Discovery; Hep G2 Cells; Humans; Malaria; Mice; Plasmodium; Species Specificity; Structure-Activity Relationship	2019
Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials. Journal of medicinal chemistry, 2020, 06-11, Volume: 63, Issue:11 Topics: Acridones; Administration, Oral; Animals; Antimalarials; Cell Survival; Disease Models, Animal; Female; Half-Life; Hep G2 Cells; Humans; Life Cycle Stages; Malaria; Male; Mice; Mice, Inbred C57BL; Plasmodium falciparum; Structure-Activity Relationship	2020
Aminoalkoxycarbonyloxymethyl Ether Prodrugs with a pH-Triggered Release Mechanism: A Case Study Improving the Solubility, Bioavailability, and Efficacy of Antimalarial 4(1 Journal of medicinal chemistry, 2021, 05-27, Volume: 64, Issue:10 Topics: Administration, Oral; Animals; Antimalarials; Cyclization; Disease Models, Animal; Ethers; Female; Half-Life; Hydrogen-Ion Concentration; Malaria; Mice; Mice, Inbred BALB C; Plasmodium falciparum; Prodrugs; Quinolones; Solubility; Structure-Activity Relationship	2021
Compounds from the Medicines for Malaria Venture Box Inhibit In Vitro Growth of Molecules (Basel, Switzerland), 2021, Nov-24, Volume: 26, Issue:23 Topics: Animals; Antiprotozoal Agents; Atovaquone; Babesia; Babesiosis; Blood-Borne Pathogens; Diminazene; Humans; Imidocarb; Malaria; Plants, Medicinal	2021
Using an antimalarial in mosquitoes overcomes Anopheles and Plasmodium resistance to malaria control strategies. PLoS pathogens, 2022, Volume: 18, Issue:6 Topics: Animals; Anopheles; Antimalarials; Atovaquone; Female; Malaria; Malaria, Falciparum; Plasmodium; Plasmodium falciparum	2022
Impact of Chemoprophylaxis on Plasmodium vivax and Plasmodium ovale Infection Among Civilian Travelers: A Nested Case-Control Study With a Counterfactual Approach on 862 Patients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 02-08, Volume: 76, Issue:3 Topics: Antimalarials; Atovaquone; Case-Control Studies; Chemoprevention; Chloroquine; Humans; Malaria; Malaria, Vivax; Plasmodium ovale; Plasmodium vivax; Travel	2023
Mitochondrially targeted proximity biotinylation and proteomic analysis in Plasmodium falciparum. PloS one, 2022, Volume: 17, Issue:8 Topics: Antimalarials; Atovaquone; Biotinylation; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Proteomics	2022
Repurposing of the Malaria Box for Babesia microti in mice identifies novel active scaffolds against piroplasmosis. Parasites & vectors, 2022, Sep-19, Volume: 15, Issue:1 Topics: Animals; Atovaquone; Babesia microti; Babesiosis; Clofazimine; Cysteine Proteases; Drug Repositioning; Imidocarb; Malaria; Mice; Theileria	2022
Symptoms of illness during travel and risk factors for non-adherence to malaria prophylaxis-a cross-sectional study in travellers from Germany. Journal of travel medicine, 2023, 05-18, Volume: 30, Issue:3 Topics: Adult; Antimalarials; Atovaquone; Cross-Sectional Studies; Drug-Related Side Effects and Adverse Reactions; Germany; Humans; Malaria; Prescriptions; Proguanil; Risk Factors; Travel; Travel-Related Illness	2023
Microbiology spectrum, 2023, 06-15, Volume: 11, Issue:3 Topics: Animals; Atovaquone; DNA, Mitochondrial; Endodeoxyribonucleases; Humans; Malaria; Malaria, Falciparum; Parasites; Plasmodium falciparum; Protozoan Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2023
Clinically relevant atovaquone-resistant human malaria parasites fail to transmit by mosquito. Nature communications, 2023, 10-12, Volume: 14, Issue:1 Topics: Animals; Anopheles; Antimalarials; Antiparasitic Agents; Atovaquone; Humans; Malaria; Malaria, Falciparum; Mice; Parasites; Plasmodium falciparum; Vaccines	2023
A case of acute generalized exanthematous pustulosis caused by exposure to Atovaquone/proguanil. Journal of travel medicine, 2020, Sep-26, Volume: 27, Issue:6 Topics: Acute Generalized Exanthematous Pustulosis; Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Proguanil	2020
Deployment and Travel Medicine Knowledge, Attitudes, Practices, and Outcomes Study (KAPOS): Malaria Chemoprophylaxis Prescription Patterns in the Military Health System. The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:1 Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Chemoprevention; Chloroquine; Doxycycline; Drug Combinations; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Military Medicine; Military Personnel; Practice Patterns, Physicians'; Primaquine; Proguanil; United States; Young Adult	2020
Exploring Ubiquinone Biosynthesis Inhibition as a Strategy for Improving Atovaquone Efficacy in Malaria. Antimicrobial agents and chemotherapy, 2021, 03-18, Volume: 65, Issue:4 Topics: Atovaquone; Humans; Malaria; Mitochondria; Oxidation-Reduction; Ubiquinone	2021
An intricate case of multidrug resistant Plasmodium falciparum isolate imported from Cambodia. Malaria journal, 2017, Apr-14, Volume: 16, Issue:1 Topics: Adult; Artemisinins; Atovaquone; Cambodia; Coinfection; Drug Combinations; Drug Resistance, Multiple; Humans; Lactones; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Proguanil; Quinine; Travel; Treatment Outcome	2017
Plasmodium knowlesi malaria in a traveller returning from the Philippines to Italy, 2016. The new microbiologica, 2017, Volume: 40, Issue:4 Topics: Antimalarials; Atovaquone; Diagnosis, Differential; Drug Combinations; Humans; Italy; Malaria; Philippines; Plasmodium knowlesi; Proguanil; Travel	2017
Hemophagocytic lymphohistiocytosis with concurrent malarial infection. BMJ case reports, 2017, Aug-07, Volume: 2017 Topics: Antimalarials; Atovaquone; Dexamethasone; Drug Therapy, Combination; Glucocorticoids; Humans; Lymphohistiocytosis, Hemophagocytic; Malaria; Male; Prednisone; Proguanil; Young Adult	2017
Acute malaria infection after atovaquone-proguanil prophylaxis. Journal of travel medicine, 2017, 03-01, Volume: 24, Issue:2 Topics: Antimalarials; Atovaquone; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Proguanil; Travel	2017
Atovaquone oral bioavailability enhancement using electrospraying technology. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Jan-01, Volume: 111 Topics: Administration, Oral; Animals; Antimalarials; Atovaquone; Biological Availability; Drug Combinations; Malaria; Mice; Plasmodium berghei; Proguanil; Rats	2018
Recrudescing Plasmodium malariae infection despite appropriate treatment in an immigrant toddler. Paediatrics and international child health, 2018, Volume: 38, Issue:4 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Atovaquone; Chloroquine; Communicable Diseases, Imported; Drug Combinations; Emigrants and Immigrants; Humans; Infant; Liberia; Malaria; Male; Plasmodium malariae; Proguanil; Recurrence; Treatment Outcome; United States	2018
Long-acting injectable atovaquone nanomedicines for malaria prophylaxis. Nature communications, 2018, 01-22, Volume: 9, Issue:1 Topics: Animals; Anopheles; Antimalarials; Atovaquone; Chemoprevention; Disease Models, Animal; Drug Carriers; Drug Resistance; Female; Humans; Malaria; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Plasmodium berghei; Theranostic Nanomedicine	2018
Abnormal Ophthalmic Examination Results and Elevated Intracranial Pressure. JAMA ophthalmology, 2018, 09-01, Volume: 136, Issue:9 Topics: Adult; Antimalarials; Atovaquone; Doxycycline; Drug Combinations; Humans; Intracranial Hypertension; Intracranial Pressure; Malaria; Male; Papilledema; Physical Examination; Proguanil; Visual Acuity; Withholding Treatment	2018
Misdiagnosis of Babesiosis as Malaria, Equatorial Guinea, 2014. Emerging infectious diseases, 2018, Volume: 24, Issue:8 Topics: Adult; Antiprotozoal Agents; Artemisinins; Atovaquone; Azithromycin; Babesia microti; Babesiosis; Diagnostic Errors; Drug Combinations; Equatorial Guinea; Female; Humans; Malaria; Primaquine; Proguanil; Spain; Travel	2018
Atovaquone-proguanil chemoprophylaxis in the era of Tafenoquine. Journal of travel medicine, 2019, Jun-01, Volume: 26, Issue:4 Topics: Aminoquinolines; Antimalarials; Atovaquone; Chemoprevention; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Proguanil; Travel	2019
Safety of atovaquone-proguanil during pregnancy. Journal of travel medicine, 2019, Jun-01, Volume: 26, Issue:4 Topics: Abortion, Spontaneous; Adolescent; Adult; Antimalarials; Atovaquone; Drug Combinations; Female; Humans; Infant, Newborn; Malaria; Middle Aged; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Premature Birth; Proguanil; Travel; Young Adult	2019
Further observation of travellers taking twice-weekly atovaquone-proguanil prophylaxis in sub-Saharan Africa. Journal of travel medicine, 2019, Jun-01, Volume: 26, Issue:4 Topics: Adult; Africa South of the Sahara; Aged; Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria; Middle Aged; Proguanil; Travel; Young Adult	2019
[Descriptive study of malaria cases in the paediatric population in a reference hospital in Valencia, Spain, between 1993 and 2015]. Anales de pediatria, 2020, Volume: 92, Issue:1 Topics: Adolescent; Age Distribution; Antimalarials; Artemisinins; Artesunate; Atovaquone; Child; Child, Preschool; Drug Combinations; Equatorial Guinea; Female; Hospitals, Community; Humans; Infant; Malaria; Male; Proguanil; Quinine; Quinolines; Retrospective Studies; Sex Distribution; Spain; Symptom Assessment	2020
Diagnosis of malaria in a traveler 9 months after returning from West Africa by Acta microbiologica et immunologica Hungarica, 2019, Sep-01, Volume: 66, Issue:3 Topics: Africa, Western; Antimalarials; Atovaquone; Drug Combinations; Germany; Humans; Malaria; Male; Middle Aged; Molecular Diagnostic Techniques; Nucleic Acid Amplification Techniques; Plasmodium ovale; Primaquine; Proguanil; Sensitivity and Specificity; Travel-Related Illness	2019
Quinolone-3-diarylethers: a new class of antimalarial drug. Science translational medicine, 2013, Mar-20, Volume: 5, Issue:177 Topics: Animals; Antimalarials; Atovaquone; Drug Resistance; Drug Synergism; Life Cycle Stages; Malaria; Malaria, Falciparum; Mice; Plasmodium falciparum; Plasmodium vivax; Proguanil; Pyridones; Quinolones	2013
Prophylactic drugs for malaria: why do we need another one? Journal of travel medicine, 1999, Volume: 6 Suppl 1 Topics: Adult; Antimalarials; Atovaquone; Chemoprevention; Child; Chloroquine; Developed Countries; Developing Countries; Drug Combinations; Female; Guidelines as Topic; Humans; Malaria; Male; Middle Aged; Patient Compliance; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Risk Factors; Travel; Travel Medicine; Young Adult	1999
Malarone Donation Program. Journal of travel medicine, 1999, Volume: 6 Suppl 1 Topics: Africa, Eastern; Antimalarials; Atovaquone; Developing Countries; Drug Combinations; Drug Industry; Humans; Internationality; Malaria; Medical Indigency; Proguanil; World Health Organization	1999
Transmission-blocking interventions eliminate malaria from laboratory populations. Nature communications, 2013, Volume: 4 Topics: Animals; Animals, Laboratory; Anopheles; Antimalarials; Atovaquone; Feeding Behavior; Female; Geography; Malaria; Mice; Models, Biological; Plasmodium berghei	2013
Use of qPCR and genomic sequencing to diagnose Plasmodium ovale wallikeri malaria in a returned soldier in the setting of a negative rapid diagnostic assay. The American journal of tropical medicine and hygiene, 2013, Volume: 89, Issue:3 Topics: Adult; Atovaquone; Base Sequence; DNA, Protozoan; Genome, Protozoan; Humans; Liberia; Malaria; Male; Military Personnel; Molecular Sequence Data; Plasmodium ovale; Proguanil; Real-Time Polymerase Chain Reaction; Sequence Alignment	2013
Formulation and characterization of atovaquone nanosuspension for improved oral delivery in the treatment of malaria. Nanomedicine (London, England), 2014, Volume: 9, Issue:5 Topics: Administration, Oral; Animals; Antimalarials; Atovaquone; Diffusion; Drug Compounding; Emulsions; Malaria; Male; Metabolic Clearance Rate; Mice; Nanocapsules; Particle Size; Rats; Rats, Sprague-Dawley; Treatment Outcome	2014
Plasmodium knowlesi and HIV co-infection in a German traveller to Thailand. Malaria journal, 2013, Aug-13, Volume: 12 Topics: Antimalarials; Atovaquone; Coinfection; Drug Combinations; Germany; HIV Infections; Humans; Malaria; Male; Middle Aged; Plasmodium knowlesi; Proguanil; Thailand; Travel; Viral Load	2013
[Malaria]. Der Internist, 2014, Volume: 55, Issue:2 Topics: Antimalarials; Artemisinins; Artesunate; Atovaquone; Drug Therapy, Combination; Humans; Malaria; Prevalence; Proguanil	2014
Phototoxic reaction associated with Malarone (atovaquone/proguanil) antimalarial prophylaxis. The Journal of dermatology, 2014, Volume: 41, Issue:4 Topics: Adult; Antimalarials; Atovaquone; Dermatitis, Phototoxic; Drug Combinations; Humans; Malaria; Male; Proguanil; Travel	2014
Causal prophylactic efficacy of primaquine, tafenoquine, and atovaquone-proguanil against Plasmodium cynomolgi in a rhesus monkey model. The Journal of parasitology, 2014, Volume: 100, Issue:5 Topics: Aminoquinolines; Animals; Antimalarials; Atovaquone; Disease Models, Animal; Drug Combinations; Macaca mulatta; Malaria; Parasitemia; Plasmodium cynomolgi; Primaquine; Proguanil	2014
Knowledge, attitudes, and practices regarding antimalarial chemoprophylaxis in U.S. Peace Corps Volunteers--Africa, 2013. MMWR. Morbidity and mortality weekly report, 2014, Jun-13, Volume: 63, Issue:23 Topics: Africa; Antimalarials; Atovaquone; Chemoprevention; Doxycycline; Drug Combinations; Health Knowledge, Attitudes, Practice; Humans; Malaria; Medication Adherence; Mefloquine; Peace Corps; Proguanil; Travel; United States; Volunteers	2014
Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold. Organic & biomolecular chemistry, 2015, Feb-07, Volume: 13, Issue:5 Topics: Amides; Animals; Antimalarials; Atovaquone; Biological Products; Cell Line; Chemistry Techniques, Synthetic; Drug Resistance; Female; Humans; Inhibitory Concentration 50; Malaria; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship; Triazines; Urea	2015
Assessment of real-time method to detect liver parasite burden under different experimental conditions in mice infected with Plasmodium yoelii sporozoites. Microbial pathogenesis, 2015, Volume: 89 Topics: Animals; Antimalarials; Atovaquone; Liver; Malaria; Mice; Parasite Load; Plasmodium yoelii; Primaquine; Real-Time Polymerase Chain Reaction; Sporozoites; Treatment Outcome	2015
Within-Host Selection of Drug Resistance in a Mouse Model of Repeated Incomplete Malaria Treatment: Comparison between Atovaquone and Pyrimethamine. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1 Topics: Amino Acid Substitution; Animals; Antimalarials; Atovaquone; Cell Nucleus; Cytochromes b; Drug Resistance; Gene Expression; Host-Parasite Interactions; Malaria; Mice; Mice, Inbred BALB C; Mitochondria; Mutation Rate; Parasitic Sensitivity Tests; Plasmodium berghei; Protozoan Proteins; Pyrimethamine; Selection, Genetic; Tetrahydrofolate Dehydrogenase; Treatment Failure	2016
Bioavailability enhancement of atovaquone using hot melt extrusion technology. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Apr-30, Volume: 86 Topics: Administration, Oral; Animals; Antimalarials; Atovaquone; Biological Availability; Drug Combinations; Drug Liberation; Hot Temperature; Malaria; Male; Mice; Plasmodium berghei; Proguanil; Rats, Sprague-Dawley; Solubility; Technology, Pharmaceutical	2016
Parasites resistant to the antimalarial atovaquone fail to transmit by mosquitoes. Science (New York, N.Y.), 2016, Apr-15, Volume: 352, Issue:6283 Topics: Animals; Anopheles; Antimalarials; Atovaquone; Cell Line; Cytochromes b; Drug Resistance; Genes, Mitochondrial; Humans; Life Cycle Stages; Malaria; Male; Mice; Mitochondria; Mutation; Plasmodium berghei; Selection, Genetic	2016
Malaria in British military personnel deployed to Sierra Leone: a case series. Journal of the Royal Army Medical Corps, 2017, Volume: 163, Issue:1 Topics: Antimalarials; Atovaquone; Cohort Studies; Doxycycline; Drug Combinations; Humans; Malaria; Mefloquine; Military Personnel; Proguanil; Sierra Leone; Treatment Outcome; United Kingdom	2017
Effectiveness of twice a week prophylaxis with atovaquone-proguanil (Malarone®) in long-term travellers to West Africa. Journal of travel medicine, 2016, Volume: 23, Issue:6 Topics: Africa South of the Sahara; Africa, Western; Antimalarials; Atovaquone; Chemoprevention; Drug Combinations; Drug Therapy, Combination; Endemic Diseases; Humans; Malaria; Proguanil; Travel	2016
The conundrum of malaria chemoprophylaxis. Journal of travel medicine, 2016, Volume: 23, Issue:6 Topics: Antimalarials; Atovaquone; Chemoprevention; Drug Therapy, Combination; Humans; Malaria; Proguanil; Travel	2016
Within-Host Selection of Drug Resistance in a Mouse Model Reveals Dose-Dependent Selection of Atovaquone Resistance Mutations. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:5 Topics: Animals; Antimalarials; Atovaquone; Cytochromes b; Drug Dosage Calculations; Drug Resistance; Malaria; Medication Errors; Mice; Mice, Inbred BALB C; Plasmodium berghei	2017
Artemether + lumefantrine: new drug. An alternative to atovaquone + proguanil. Prescrire international, 2008, Volume: 17, Issue:94 Topics: Adolescent; Adult; Africa; Animals; Antimalarials; Artemisinins; Atovaquone; Child; Clinical Trials as Topic; Drug Approval; Drug Therapy, Combination; Ethanolamines; Europe; Fluorenes; Humans; Malaria; Plasmodium falciparum; Proguanil	2008
Well-tolerated chemoprophylaxis uniformly prevented Swedish soldiers from Plasmodium falciparum malaria in Liberia, 2004-2006. Military medicine, 2008, Volume: 173, Issue:12 Topics: Animals; Antimalarials; Atovaquone; Chemoprevention; Female; Humans; Liberia; Malaria; Male; Mefloquine; Military Medicine; Military Personnel; Plasmodium falciparum; Proguanil; Retrospective Studies; Surveys and Questionnaires; Sweden	2008
Atovaquone + proguanil: new indication. For children weighing as little as 5 kg; an inconvenient form. A flavoured syrup would be better suited to infants and young children. Prescrire international, 2009, Volume: 18, Issue:101 Topics: Administration, Oral; Antimalarials; Atovaquone; Body Weight; Chemistry, Pharmaceutical; Child; Child, Preschool; Dosage Forms; Drug Administration Schedule; Drug Approval; Drug Combinations; France; Humans; Infant; Malaria; Malaria, Falciparum; Proguanil; Tablets	2009
Probing binding determinants in center P of the cytochrome bc(1) complex using novel hydroxy-naphthoquinones. Biochimica et biophysica acta, 2010, Volume: 1797, Issue:1 Topics: Animals; Antimalarials; Atovaquone; Cattle; Cytochromes b; Electron Transport Complex III; Humans; Kinetics; Malaria; Naphthoquinones; Plasmodium falciparum; Pneumocystis	2010
Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene. Malaria journal, 2010, May-21, Volume: 9 Topics: Animals; Antimalarials; Atovaquone; Cytochromes b; DNA, Protozoan; Drug Resistance; Female; Genotype; Malaria; Mice; Parasitic Sensitivity Tests; Plasmodium chabaudi; Point Mutation	2010
Community management of anti-malarials in Africa and iatrogenic risk. Journal of tropical pediatrics, 2011, Volume: 57, Issue:3 Topics: Antimalarials; Atovaquone; Child; Community Health Services; Contraindications; Cote d'Ivoire; Diagnostic Errors; Drug Combinations; Female; Humans; Iatrogenic Disease; Liver Failure, Acute; Malaria; Proguanil; Pyrimethamine; Sulfadoxine	2011
Atovaquone-proguanil use in early pregnancy and the risk of birth defects. Archives of internal medicine, 2011, Feb-14, Volume: 171, Issue:3 Topics: Abnormalities, Drug-Induced; Antimalarials; Atovaquone; Cohort Studies; Cross-Sectional Studies; Denmark; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Age; Humans; Infant, Newborn; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Product Surveillance, Postmarketing; Proguanil; Registries	2011
Marked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxis. Malaria journal, 2011, May-21, Volume: 10 Topics: Adult; Anti-HIV Agents; Antimalarials; Atovaquone; Chemoprevention; Drug Combinations; Drug Interactions; Female; HIV Infections; Humans; Malaria; Nitriles; Plasma; Proguanil; Pyridazines; Pyrimidines; Saquinavir	2011
Prophylactic use of antimalarials during pregnancy. Canadian family physician Medecin de famille canadien, 2011, Volume: 57, Issue:11 Topics: Antimalarials; Atovaquone; Chemoprevention; Chloroquine; Doxycycline; Drug Combinations; Female; Humans; Hydroxychloroquine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Primaquine; Proguanil; Travel	2011
Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug. The Journal of infectious diseases, 2012, Apr-15, Volume: 205, Issue:8 Topics: Animals; Antimalarials; Atovaquone; Cell Line, Tumor; Decoquinate; Drug Evaluation, Preclinical; Hepatocytes; Humans; Malaria; Mitochondria; Models, Molecular; Molecular Structure; Plasmodium; Protein Conformation	2012
Anti-malarial chemoprophylaxis following evacuation from Afghanistan. Journal of the Royal Army Medical Corps, 2012, Volume: 158, Issue:1 Topics: Afghan Campaign 2001-; Antimalarials; Atovaquone; Chemoprevention; Chloroquine; Clinical Audit; Doxycycline; Drug Combinations; Drug Prescriptions; Humans; Malaria; Mefloquine; Military Personnel; Proguanil	2012
Standby emergency treatment of malaria in travelers: experience to date and new developments. Expert review of anti-infective therapy, 2012, Volume: 10, Issue:5 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Atovaquone; Chloroquine; Diagnostic Tests, Routine; Drug Combinations; Emergency Treatment; Ethanolamines; Female; Fluorenes; Geography; Guidelines as Topic; Health Policy; Humans; Malaria; Plasmodium; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Sensitivity and Specificity; Travel; Travel Medicine	2012
Therapy of uncomplicated falciparum malaria in Europe: MALTHER - a prospective observational multicentre study. Malaria journal, 2012, Jun-22, Volume: 11 Topics: Adolescent; Adult; Aged; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Atovaquone; Drug Combinations; Drug Therapy; Ethanolamines; Europe; Female; Fluorenes; Humans; Malaria; Male; Mefloquine; Middle Aged; Proguanil; Prospective Studies; Young Adult	2012
Questionnaire-based analysis of atovaquone-proguanil compared with mefloquine in the chemoprophylaxis of malaria in non-immune Japanese travelers. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2013, Volume: 19, Issue:1 Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Chemoprevention; Child; Drug Combinations; Female; Humans; Japan; Malaria; Male; Mefloquine; Middle Aged; Proguanil; Surveys and Questionnaires; Travel; Young Adult	2013
Field evaluation of rapid diagnostic tests for malaria in Yaounde, Cameroon. Acta tropica, 2013, Volume: 125, Issue:2 Topics: Adult; Antigens, Protozoan; Atovaquone; Cameroon; Child, Preschool; Drug Combinations; Follow-Up Studies; Humans; Infant; L-Lactate Dehydrogenase; Likelihood Functions; Malaria; Parasite Load; Parasitemia; Plasmodium; Predictive Value of Tests; Proguanil; Protozoan Proteins; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity; Time Factors; Treatment Outcome	2013
Relapsing malaria: two cases of malaria presenting 8 months after return from Africa despite adherence to antimalarial chemoprophylaxis. The British journal of general practice : the journal of the Royal College of General Practitioners, 2012, Volume: 62, Issue:603 Topics: Adolescent; Africa; Antimalarials; Atovaquone; Delayed Diagnosis; Drug Combinations; Humans; Malaria; Male; Medication Adherence; Plasmodium ovale; Proguanil; Recurrence; Travel; United Kingdom	2012
[Preventive vaccination for travel. Every dog has it, but only every 10th grandmother]. MMW Fortschritte der Medizin, 2002, Sep-19, Volume: 144, Issue:38 Topics: Adult; Aged; Animals; Antimalarials; Atovaquone; Child; Dogs; Drug Combinations; Germany; Humans; Malaria; Naphthoquinones; Proguanil; Travel; Tropical Medicine; Vaccination	2002
The safety of atovaquone/proguanil in long-term malaria prophylaxis of nonimmune adults. Journal of travel medicine, 2003, Volume: 10 Suppl 1 Topics: Adult; Antimalarials; Atovaquone; Denmark; Drug Administration Schedule; Drug Combinations; Eritrea; Humans; Malaria; Male; Military Personnel; Naphthoquinones; Proguanil; Surveys and Questionnaires; Travel	2003
Post-marketing surveillance: adverse events during long-term use of atovaquone/proguanil for travelers to malaria-endemic countries. Journal of travel medicine, 2003, Volume: 10 Suppl 1 Topics: Antimalarials; Atovaquone; Drug Combinations; Endemic Diseases; Europe; Female; Humans; Longitudinal Studies; Malaria; Male; Naphthoquinones; Product Surveillance, Postmarketing; Proguanil; Prospective Studies; Surveys and Questionnaires; Travel	2003
Malaria and children: the risks, precautions, and the nurse's role. Professional nurse (London, England), 2003, Volume: 19, Issue:1 Topics: Animals; Antimalarials; Atovaquone; Chemoprevention; Child; Culicidae; Doxycycline; Drug Combinations; Humans; Insect Bites and Stings; Malaria; Mefloquine; Naphthoquinones; Proguanil; Travel	2003
Diagnosis and treatment of malaria in children. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Nov-15, Volume: 37, Issue:10 Topics: Animals; Antimalarials; Atovaquone; Child; Chloroquine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Proguanil; Pyrimethamine; Sulfadoxine	2003
A malaria outbreak following a British military deployment to Sierra Leone. The Journal of infection, 2004, Volume: 48, Issue:2 Topics: Antimalarials; Atovaquone; Disease Outbreaks; Doxycycline; Drug Combinations; Humans; Malaria; Male; Mefloquine; Military Personnel; Naphthoquinones; Proguanil; Sierra Leone	2004
A malaria outbreak following a British military deployment to Sierra Leone. The Journal of infection, 2005, Volume: 50, Issue:2 Topics: Antimalarials; Atovaquone; Chemoprevention; Disease Outbreaks; Doxycycline; Drug Combinations; Humans; Malaria; Male; Mefloquine; Military Personnel; Naphthoquinones; Proguanil; Sierra Leone; United Kingdom	2005
Cytochrome b mutations that modify the ubiquinol-binding pocket of the cytochrome bc1 complex and confer anti-malarial drug resistance in Saccharomyces cerevisiae. The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17 Topics: Amino Acid Sequence; Animals; Antimalarials; Atovaquone; Cytochromes b; Dose-Response Relationship, Drug; Electron Transport Complex III; Inhibitory Concentration 50; Kinetics; Malaria; Models, Molecular; Molecular Sequence Data; Mutation; Naphthoquinones; Oxygen Consumption; Plasmodium falciparum; Point Mutation; Protein Binding; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Time Factors; Ubiquinone	2005
Effectiveness of antimalarial drugs. The New England journal of medicine, 2005, Jul-28, Volume: 353, Issue:4 Topics: Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria; Mefloquine; Naphthoquinones; Proguanil	2005
[Malaria prophylaxis for long-term travellers and expatriates]. Ugeskrift for laeger, 2005, Oct-17, Volume: 167, Issue:42 Topics: Antimalarials; Atovaquone; Chloroquine; Counseling; Doxycycline; Drug Combinations; Humans; Insect Bites and Stings; Malaria; Mefloquine; Mosquito Control; Naphthoquinones; Proguanil; Risk Assessment; Risk Factors; Travel	2005
[Ineffective change of antimalaria prophylaxis to Artemisia vulgaris in a group travelling to West Africa]. Ugeskrift for laeger, 2005, Oct-24, Volume: 167, Issue:43 Topics: Africa, Western; Antimalarials; Atovaquone; Doxycycline; Drug Combinations; Female; Humans; Malaria; Male; Mefloquine; Naphthoquinones; Plant Preparations; Proguanil; Surveys and Questionnaires; Travel	2005
Plasmodium falciparum malaria associated with mefloquine failure in Gambia. Pharmacotherapy, 2006, Volume: 26, Issue:10 Topics: Adult; Animals; Antimalarials; Atovaquone; Chemoprevention; Gambia; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Proguanil; Risk Assessment; Risk Factors; Travel; Treatment Failure; United States	2006
In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models. Experimental parasitology, 2007, Volume: 115, Issue:3 Topics: Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Erythrocytes; Female; Heterocyclic Compounds, 1-Ring; Humans; Malaria; Mice; Parasitemia; Parasitic Sensitivity Tests; Peroxides; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinolines; Spiro Compounds	2007
Inadequate chemoprophylaxis and the risk of malaria. Australian family physician, 2007, Volume: 36, Issue:12 Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Australia; Chemoprevention; Doxycycline; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Papua New Guinea; Proguanil; Retrospective Studies; Risk Factors	2007
Malaria chemoprophylaxis: what do the travelers choose, and how does pretravel consultation influence their final decision. The American journal of tropical medicine and hygiene, 2007, Volume: 77, Issue:6 Topics: Adolescent; Adult; Antimalarials; Atovaquone; Consumer Health Information; Decision Making; Doxycycline; Drug Combinations; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Proguanil; Prospective Studies; Switzerland; Time Factors; Travel	2007
Mutation underlying resistance of Plasmodium berghei to atovaquone in the quinone binding domain 2 (Qo(2)) of the cytochrome b gene. Parasitology international, 2008, Volume: 57, Issue:2 Topics: Amino Acid Sequence; Animals; Antimalarials; Atovaquone; Benzoquinones; Cytochrome b Group; Drug Resistance; Malaria; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Parasitemia; Parasitic Sensitivity Tests; Plasmodium berghei	2008
Acridinediones: selective and potent inhibitors of the malaria parasite mitochondrial bc1 complex. Molecular pharmacology, 2008, Volume: 73, Issue:5 Topics: Acridines; Animals; Antimalarials; Atovaquone; Cattle; Drug Synergism; Electron Transport Complex III; Heme; Hemeproteins; Humans; Malaria; Male; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Rats, Wistar; Saccharomyces cerevisiae	2008
Failure of atovaquone/proguanil to prevent Plasmodium ovale malaria in traveler returning from Cameroon. Travel medicine and infectious disease, 2008, Volume: 6, Issue:3 Topics: Aged; Animals; Antimalarials; Atovaquone; Cameroon; Diagnosis, Differential; Fever; France; Headache; Humans; Malaria; Male; Plasmodium ovale; Proguanil; Travel	2008
Cytotoxic effects of inhibitors of de novo pyrimidine biosynthesis upon Plasmodium falciparum. Biochemistry, 1994, May-03, Volume: 33, Issue:17 Topics: Amides; Animals; Antimalarials; Atovaquone; Bicarbonates; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dihydroorotase; Dihydroorotate Dehydrogenase; Erythrocytes; Humans; Kinetics; Malaria; Naphthoquinones; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium falciparum; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose	1994
Inhibitory action of the anti-malarial compound atovaquone (566C80) against Plasmodium berghei ANKA in the mosquito, Anopheles stephensi. Parasitology, 1994, Volume: 108 ( Pt 4) Topics: Animals; Anopheles; Antimalarials; Atovaquone; Enzyme-Linked Immunosorbent Assay; Female; Insect Vectors; Malaria; Mice; Naphthoquinones; Plasmodium berghei; Protozoan Proteins	1994
Malarone-donation programme in Africa. Lancet (London, England), 1997, Nov-29, Volume: 350, Issue:9091 Topics: Africa; Altruism; Antimalarials; Atovaquone; Developing Countries; Drug Combinations; Drug Industry; Humans; Malaria; Naphthoquinones; Proguanil	1997
Adverse effects of antimalarial prophylactic drugs: an important consideration in the risk-benefit equation. The Annals of pharmacotherapy, 1998, Volume: 32, Issue:10 Topics: Animals; Anti-Bacterial Agents; Antimalarials; Atovaquone; Azithromycin; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Naphthoquinones; Plasmodium falciparum; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Risk Assessment	1998
Malaria prophylaxis for the 1990s and beyond. British journal of hospital medicine, 1997, Dec-10, Volume: 58, Issue:11 Topics: Antimalarials; Atovaquone; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Mefloquine; Naphthoquinones; Proguanil	1997
Inhibition of the mosquito transmission of Plasmodium berghei by Malarone (atovaquone-proguanil). Annals of tropical medicine and parasitology, 2000, Volume: 94, Issue:5 Topics: Animals; Antimalarials; Atovaquone; Chromatography, High Pressure Liquid; Culicidae; Disease Vectors; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Mice; Naphthoquinones; Plasmodium berghei; Proguanil; Rats; Rats, Wistar	2000
Atovaquone and proguanil hydrochloride. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2000, Dec-01, Volume: 57, Issue:23 Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Child; Child, Preschool; Drug Combinations; Drug Interactions; Humans; Malaria; Naphthoquinones; Proguanil	2000
Efficacy of atovaquone-proguanil? Lancet (London, England), 2001, Apr-21, Volume: 357, Issue:9264 Topics: Antimalarials; Atovaquone; Doxycycline; Drug Combinations; Humans; Malaria; Naphthoquinones; Proguanil; Travel	2001
[Expanded arsenal for prevention and therapy. What is the value of the new malaria drugs? (interview by Waltraut Paukstadt)]. MMW Fortschritte der Medizin, 2001, Jul-05, Volume: 143, Issue:26-27 Topics: Antimalarials; Atovaquone; Drug Administration Schedule; Drug Combinations; Humans; Malaria; Mefloquine; Naphthoquinones; Proguanil; Treatment Outcome	2001
The causal prophylactic activity of the novel hydroxynaphthoquinone 566C80 against Plasmodium berghei infections in rats. Acta Leidensia, 1989, Volume: 58, Issue:2 Topics: Animals; Antimalarials; Atovaquone; Drug Evaluation, Preclinical; Erythrocytes; Female; Malaria; Naphthoquinones; Plasmodium berghei; Rats; Rats, Inbred BN	1989