Page last updated: 2024-08-25

atovaquone and Malaria, Falciparum

atovaquone has been researched along with Malaria, Falciparum in 225 studies

Research

Studies (225)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	26 (11.56)	18.2507
2000's	95 (42.22)	29.6817
2010's	76 (33.78)	24.3611
2020's	28 (12.44)	2.80

Authors

Authors	Studies
Baniecki, ML; Clardy, J; Wirth, DF	1
Bertaux, L; Bogreau, H; Bouchiba, H; Garnotel, E; Kraemer, P; Parzy, D; Pradines, B; Rogier, C; Savini, H; Simon, F	1
Ane, M; Baziard-Mouysset, G; El Hage, S; Marjorie, M; Payard, M; Stigliani, JL; Vial, H	1
Brun, R; Carballeira, NM; Herman, R; Kappe, SH; Lauinger, IL; Perozzo, R; Sanabria, D; Tarun, A; Tasdemir, D; Zloh, M	1
Clark, JA; Connelly, MC; El Mazouni, F; Furimsky, A; Gow, J; Guiguemde, WA; Guy, RK; Iyer, L; Kyle, DE; Min, J; Mirsalis, J; Parman, T; Phillips, MA; Pradhan, A; Zhang, Y; Zhu, F	1
Clardy, J; Derbyshire, ER; Mota, MM; Prudêncio, M	1
da Rocha, DR; Ferreira, VF; Garcia, CR; Gaur, P; Santos, IO; Sharma, A	1
Fidock, DA; Flannery, EL; Winzeler, EA	1
Angulo-Barturen, I; Avery, VM; Awasthy, D; Balasubramanian, V; Bandodkar, B; Barde, SP; Bharath, S; Chinnapattu, M; Duffy, S; Ferrer, S; Gamo, FJ; Hameed P, S; Hosagrahara, V; Iyer, PS; Jatheendranath, S; Jiménez-Díaz, MB; Kavanagh, S; Koushik, K; Lukens, AK; Magistrado, PA; Manjrekar, P; Martínez, MS; Morayya, S; Mukherjee, K; Narayan, C; Narayanan, S; Panduga, V; Patil, V; Prabhakar, KR; Raichurkar, A; Ramachandran, S; Rautela, N; Reddy, J; Rudrapatna, SS; Sambandamurthy, VK; Sanz, LM; Saralaya, R; Shanbag, G; Sinha, A; Srivastava, A; Viswanath, P; Waterson, D; Wirth, DF	1
Iyer, PS; Kannan, M; Khan, FR; Raichurkar, AV	1
Bu, W; Campo, B; Ding, J; Easom, EE; Freund, YR; Gamo, FJ; Ge, M; Guo, D; Jacobs, RT; Li, L; Plattner, JJ; Rosenthal, PJ; Sanders, V; Sanz, LM; Yang, Y; Zhang, YK	1
Angulo-Barturen, Í; Bahamontes-Rosa, N; Ballell-Pages, L; Berry, NG; Biagini, GA; Blackman, MJ; Calderón, F; Castañeda, P; Crespo, B; de Cózar, C; de Mercado, J; Fernández, J; Frigerio, M; Guijarro, L; Jiménez-Díaz, MB; Martínez-Martínez, MS; McConville, M; Nixon, GL; O'Neill, PM; Santos-Villarejo, Á; Sanz, LM; Ward, SA; Washbourn, G	1
Berry, P; Campo, B; Cao, J; Ciaravino, V; Easom, EE; Erve, JCL; Freund, YR; Gamo, FJ; Guo, D; Jacobs, RT; Plattner, JJ; Rosenthal, PJ; Sanz, LM; Zhang, YK	1
Andrews, KT; Antonova-Koch, Y; Avery, VM; Diedrich, D; Duffy, S; Fisher, G; Gebru, T; Hansen, FK; Held, J; Hesping, E; Kurz, T; Meister, S; Schöler, A; Stenzel, K; Winzeler, EA	1
Boonhok, R; Chakrabarti, D; Huang, G; Melendez, J; Miao, J; Min, H; Solano, CM; Yu-Alfonzo, S; Yuan, Y	1
Beteck, RM; Legoabe, LJ; Patel, OPS	1
Augereau, JM; Benoit-Vical, F; Deraeve, C; Jimenez, T; Mustière, R; Nguyen, M; Ouji, M	1
Akao, Y; Avery, VM; Charman, SA; Chen, G; Chen, X; Chiu, FCK; Cho, N; Crespo, B; Dechering, KJ; Duffy, S; Kamaura, M; Katneni, K; Laleu, B; Lucantoni, L; Ochida, A; Sanz, LM; Shackleford, DM; Sturm, A; Wang, B; White, KL; Wittlin, S	1
Ashton, M; Bergqvist, Y; Björkman, A; Gil, JP; Thapar, MM; Ursing, J	1
Adams, KL; Bopp, S; Catteruccia, F; Dabiré, RK; Diabaté, A; Hien, DFS; Lefèvre, T; Ma, E; Paré, PSL; Paton, DG; Probst, AS; Shaw, WR; Singh, N; Volkman, SK; Wirth, DF; Yerbanga, RS	1
Ahiya, AI; Lamb, IM; Lindner, SE; Mather, MW; Mell, JC; Morrisey, J; Rios, KT; Shukla, A; Vaidya, AB	1
Dass, S; Ke, H; Ling, L; Mather, MW; Morrisey, JM; Vaidya, AB	1
Ji, J; Sundquist, J; Sundquist, K; Zhang, N	1
Alruwaili, M; Elahi, R; Prigge, S; Shapiro, T; Sullivan, D; Sutherland, C; van Schalkwyk, D	1
Aonsri, C; Boonyalai, N; Bunsermyos, W; Chaorattanakawee, S; Dondorp, AM; Imaram, W; Imwong, M; Kosaisavee, V; Kunasol, C; Mungthin, M; Saunders, D; Suwannasin, K; Thamnurak, C	1
Blanchard, A; Hine, P	1
Castañeda-Mogollón, D; Kamaliddin, C; Kuhn, S; Lang, R; Pillai, DR; Toppings, NB	1
Arun Kumar, K; Bhattacharyya, MK; Bhattacharyya, S; Dey, S; Fangaria, N; Padhi, S; Roy, A; Singh, P; Tabassum, W	1
B Henry, N; Bolscher, JM; Bousema, T; Collins, KA; Dechering, KJ; Diarra, A; Guelbéogo, WM; Nébié, I; Ouédraogo, N; Pietro, A; S Coulibaly, A; S Sermé, S; Sirima, SB; Sombié, S; Soulama, I; T G Huijs, T; Tiono, AB; Zongo, S	1
Bakshi, RP; Balta, VA; Canonizado, MA; Dziedzic, AG; Elahi, R; Jedlicka, AE; Mann, A; Mlambo, G; Nenortas, E; Owen, A; Prigge, ST; Romero-Rodriguez, K; Sayeed, A; Shapiro, TA; Sinnis, P; Stiffler, D; Sullivan, DJ; Tripathi, AK	1
Chibale, K; Fidock, DA; Goldberg, DE; Istvan, ES; Lee, MCS; Llinás, M; Murithi, JM; Ottilie, S; Owen, ES; Vanaerschot, M; Winzeler, EA	1
Borgans, F; Eisermann, P; Giesbrecht, K; Goetsch, U; Just-Nübling, G; Kessel, J; Lieberknecht, S; Muntau, B; Schork, J; Tappe, D; Wieters, I; Wolf, T	1
Amalvict, R; Benoit, N; Chevalier, A; Delaunay, P; Fonta, I; Jeandel, PY; Madamet, M; Marty, P; Massamba, L; Mondain, V; Mosnier, J; Pomares, C; Pradines, B	1
Abubaker, M; Bryce, RA; Burusco, KK; Fernández-Álvaro, E; Gutnov, A; Matthews, H; Nirmalan, N; Panwar, P; Wilkinson, J	1
Arsuaga, M; Barreiro, P; de la Calle, F; de Miguel, R; Diaz, M; Loli-Ausejo, D; Tarin, EJ; Trigo, E	1
Kelley, J; L'Episcopia, M; Lucchi, N; Menegon, M; Nour, BY; Nurahmed, AM; Patel, D; Perrotti, E; Ravishankar, S; Schmedes, S; Severini, C; Talha, AA; Talundzic, E	1
Anvikar, AR; Ashley, EA; Chandramohan, D; Cohee, LM; D'Alessandro, U; Genton, B; Gilder, ME; Guérin, PJ; Juma, E; Kalilani-Phiri, L; Kennon, K; Kuepfer, I; Laufer, MK; Lwin, KM; Mansoor, R; McGready, R; Meshnick, SR; Mosha, D; Mwapasa, V; Mwebaza, N; Nambozi, M; Ndiaye, JA; Nosten, F; Nyunt, M; Ogutu, B; Parikh, S; Paw, MK; Phyo, AP; Pimanpanarak, M; Piola, P; Rijken, MJ; Saito, M; Sriprawat, K; Stepniewska, K; Tagbor, HK; Tarning, J; Tinto, H; Valéa, I; Valecha, N; White, NJ; Wiladphaingern, J	1
Carnino, L; Chappuis, F; Hulo, C; Konan, DB; Puppa, G	1
Aydemir, O; Bailey, JA; Brazeau, NF; Gosi, P; Lin, JT; Lon, C; Marsh, PW; Moser, KA; Muller, MS; Na, YB; Park, Z; Saunders, DL; Sok, S; Spring, M; Waltmann, A; Wojnarski, M	1
Blanshard, A; Hine, P	1
Husen, P; Jacobsen, L; Solov'yov, IA	1
Chenet, SM; Fernandez, J; Jercic, MI; Lucchi, NW; Oyarce, A; Tapia-Limonchi, R; Tejedo, JR; Udhayakumar, V; Weitzel, T	1
Abla, N; Chalon, S; Chughlay, MF; Haouala, A; Hutter, B; Lorch, U; Macintyre, F; Marie Tchouatieu, A	1
Blake, LD; Iyamu, ID; Johnson, ME; Kyle, DE; Manetsch, R; McQueen, A; Shaikh, AK; Shultis, MW; Siegel, SV	1
Arguin, PM; Mace, KE; Minta, AA; Tan, KR	1
Maayan, N; Pace, C; Saunders, R; Sinclair, D; Tickell-Painter, M	1
Burrow, R; Chis Ster, I; Kremsner, PG; Krishna, S; Staines, HM; Teo, BH	1
Charunwatthana, P; Chotivanich, K; Dondorp, AM; Färnert, A; Herder, C; Holmer, E; Kiwuwa, MS; Kristensen, J; Lee, SJ; Leitgeb, AM; Lindgren, M; Moll, K; Rueangveerayut, R; Sila, P; Silamut, K; Tarning, J; Uthaisin, C; Wahlgren, M	1
Amalia, E; Balogun, EO; Harada, S; Hartuti, ED; Inaoka, DK; Kita, K; Komatsuya, K; Kuroda, M; Matsuo, Y; Miller, RJ; Miyazaki, Y; Mori, M; Nozaki, T; Nugroho, NB; Prabandari, EE; Pramisandi, A; Sadikin, M; Saimoto, H; Shiba, T; Shiomi, K; Waluyo, D; Watanabe, YI; Xinying, W	1
Betz, W; Bial, J; Billman, Z; Camargo, N; Campo, B; Charman, SA; Chuenchob, V; Fishbaugher, M; Flannery, EL; Foquet, L; Kappe, SH; Lee, J; Mikolajczak, SA; Murphy, SC; Navarro, MJ; Nguyen, T; Olsen, TM; Phillips, MA; Sack, BK; Saunders, J; Schafer, C; Wilson, EM	1
Javelle, E; Loarer, G; Michel, R; Perisse, A; Simon, F; Velut, G	1
Agarwal, P; Anvikar, AR; Pillai, CR; Srivastava, K	1
Argy, N; Houzé, S; Joste, V; Kamaliddin, C	1
Akkaya, B; Aydın Teke, T; Bayhan, Gİ; Gayretli Aydın, ZG; Kaman, A; Tanır, G	1
Horii, T; Tougan, T; Toya, Y; Uchihashi, K	1
Buckee, CO; Catteruccia, F; Childs, LM; Holmdahl, IE; Itoe, MA; Paton, DG	1
Buffet, P; Chambrion, C; Chartrel, N; Mouri, O; Ndour, PA; Roussel, C; Smith, B; Smith, P; Thellier, M; Wojnarski, M	1
Bopp, SE; Bright, AT; Denchi, EL; Dharia, NV; Fidock, DA; Johnston, GL; Luna, FL; Manary, MJ; McCormack, S; McNamara, CW; Plouffe, D; Walker, JR; Winzeler, EA	1
Angulo-Barturen, I; Avery, VM; Bathurst, I; Burrows, JN; Charman, SA; Cross, RM; Delves, MJ; Duffy, S; Ferrer, S; Forquer, IP; Gamo, FJ; Guy, RK; Herreros, E; Jiménez-Díaz, MB; Kelly, JX; Kocken, CHM; Kyle, DE; LaCrue, AN; Li, Y; Manetsch, R; Marfurt, J; Mather, MW; Morrisey, JM; Mutka, T; Nilsen, A; Noviyanti, R; Price, RN; Riscoe, MK; Ryan, E; Saenz, FE; Sanz, LM; Sebayang, BF; Shackleford, DM; Siegl, P; Sinden, RE; Steuten, J; Vaidya, AB; White, KL; Winter, RW; Wirjanata, G; Zeeman, AM	1
Shanks, GD	1
Beerahee, M	1
Chulay, JD; Kremsner, PG; Looareesuwan, S	1
Chulay, JD; Kremsner, PG; Scott, TR; Shanks, GD; Shapiro, TA; Sukwa, TY; van der Berg, JD	1
Bellettre, X; Bouchaud, O; Michel, JF; Pull, L; Siriez, JY	1
Berrevoets, MA; Dofferhoff, AS; Meis, JF; Sprong, T	1
De Castro, N; Gallien, S; Hamane, S; Molina, JM; Taieb, F	1
Bloch, M; Bouchaud, O; Bourée, P; Cailhol, J; Campa, P; Consigny, PH; Cordel, H; Fain, O; Godineau, N; Gros, H; Matheron, S; Ralaimazava, P	1
Bastiaens, GJ; Boulaksil, M; de Mast, Q; Gunasekera, A; Hoffman, SL; Pop, G; Sauerwein, RW; van der Ven, AJ; van Meer, MP	1
David, K; Møller, CH	1
Clain, J; Cottrell, G; Hubert, V; Le Bras, J; Musset, L	1
Almelli, T; Basco, LK; Debue, C; Djaman Allico, J; Foumane Ngane, V; Tahar, R; Whegang Youdom, S	1
Amore, A; Calitri, C; Camilla, R; Garazzino, S; Peruzzi, L; Tovo, PA	1
Hickman, MR; Li, Q; Melendez, V; Miller, SR; Ogutu, B; Otieno, W; Polhemus, M; Remich, S; Smith, B; Teja-Isavadharm, P; Weina, PJ	1
Dondorp, AM; Maude, RJ; Nguon, C; White, LJ; White, NJ	1
Akhoon, BA; Gupta, SK; Shukla, Y; Singh, KP; Varshney, M	1
Grynberg, S; Kopel, E; Lachish, T; Meltzer, E; Schwartz, E	1
Chai, JY; Choi, JS; Je, JH; Jung, BK; Kim, MJ; Lee, HJ; Na, YJ; Park, SH; Seo, JH; Song, JY	1
Akala, HM; Bulimo, WD; Eyase, FL; Imbuga, MO; Ingasia, LA; Johnson, JD; Kamau, E; Opot, BH	1
Alves Dos Santos, R; de Oliveira Silva, E; Dos Santos Gonçalves, N; Jacometti Cardoso Furtado, NA	1
Callens, S; Donck, J; Ommeslag, D; Rogge, S; Van Acker, J; Vantomme, B	1
Dinter, D; Domijan, AM; Gajski, G; Garaj-Vrhovac, V	1
Croft, AM; Jacquerioz, FA	2
Harris, DM; Matcha, GV; Steele, HP	1
Chann, S; Chaorattanakawee, S; Chuor, CM; Gosi, P; Gregory, C; Ittiverakul, M; Kuntawunginn, W; Lanteri, C; Lon, C; Prom, S; Saunders, DL; Somethy, S; Spring, MD	1
Lachish, T; Schwartz, E	1
Akala, HM; Auschwitz, JM; Cheruiyot, AC; Gaona, HW; Hickman, MR; Johnson, JD; Kamau, E; Lee, PJ; Leed, SE; Murthy, T; Okello, CO; Talwar, M; Yeda, RA	1
Barata, L; Boutbibe, K; Clain, J; Franetich, JF; Houzé, P; Mazier, D; Zanghi, G	1
Arguin, PM; Barnwell, JW; Biliya, S; Halsey, ES; Plucinski, MM; Silva-Flannery, LM; Talundzic, E; Udhayakumar, V; Vannberg, F	1
Bergman, LW; Daly, TM; Jenkins, BJ; Mather, MW; Morrisey, JM; Vaidya, AB	1
Bouchaud, O; Bruneel, F; Camus, C; Caumes, E; Choquet, C; Corne, P; Durand, R; Gibot, S; Girard, PM; Houze, S; Huisse, MG; Kalloumeh, A; Le Bras, J; Matheron, S; Megarbane, B; Mira, JP; Peytel, E; Roy, C; Simon, F; Tubach, F; Villers, D; Wolff, M	1
Forquer, IP; Kelly, JX; Li, Y; Morrisey, JM; Nilsen, A; Pou, S; Riscoe, MK; Smilkstein, MJ; Stickles, AM; Vaidya, AB; Winter, RW	1
Aprahamian, A; Argy, N; Aurégan, C; Cheron, G; Clain, J; Hubert, V	1
Deakin, J; Idris-Usman, M; Matthews, H; Nirmalan, NJ; Rajab, M	1
Banura, P; Guler, JL; Houpt, E; Huang, F; Jacob, ST; Laufer, MK; Liu, J; Moore, CC; Pholwat, S; Stroup, S	1
Ogutu, B; Otieno, W; Polhemus, ME; Remich, SA; Walsh, DS	1
Berens-Riha, N; Eshetu, T; Girma, T; Gürkov, R; Hempel, JM; Krause, E; Löscher, T; Mamo, Y; Miranda, IB; Schmidt, M	1
Benoit-Vical, F; Berry, A; Garcia-Alvarez, MC; Nicolau, ML; Olagnier, D; Soh, PN; Witkowski, B	1
Burke, M; Chiodini, PL; Fivelman, QL; Klein, JL; Laundy, M; Pasvol, G; Price, N; Sutherland, CJ	1
bin Reza, F; Chiodini, PL; Doherty, JF; Fifer, H; Gothard, P; Haustein, T; Nicholas, M; Njimgye-Tekumafor, NE; Pearce, RJ; Polley, SD; Sutherland, CJ	1
Boggild, AK; Kain, KC; Katz, K; Krudsood, S; Liles, WC; Looareesuwan, S; Patel, SN; Serghides, L; Tangpukdee, N; Wilairatana, P	1
Eaton, L	1
Batty, AJ; Jones, ME; Zuckerman, JN	1
Gan, LS; Loh, JP	1
Schofield, S; Tepper, M	1
Berens-Riha, N; Eshetu, T; Fekadu, S; Gürkov, R; Hölscher, M; Löscher, T; Miranda, IB; Tadesse, Z	1
Forestier, E; Labe, A; Lecomte, C; Raffenot, D; Rogeaux, O	1
Ganesan, SM; Ke, H; Laroiya, K; Mather, MW; Morrisey, JM; Painter, HJ; Phillips, MA; Rathod, PK; Vaidya, AB	1
Terlouw, DJ; van Eijk, AM	1
Bautista, JM; Diez, A; García-Granados, A; Marín-García, P; Moneriz, C; Puyet, A	1
Baron, S; Contentin, L; Desoubeaux, G; Grammatico-Guillon, L; Thanh, HD	1
Clemens, EG; Deye, GA; Dumler, JS; Fracisco, S; Macareo, L; Magill, AJ; Miller, L; Miller, RS; Murphy, J; Salas, CJ; Smith, BL; Sousa, JC; Tosh, D	1
Lewthwaite, P; Uriel, A	1
Barón, C; Carrasquilla, G; Cousin, M; Fisher, LM; Lefèvre, G; Monsell, EM; Sander, O; Walter, V	1
Kikuchi, T; Kimura, M; Koga, M; Maruyama, H; Miura, T	1
Benoit, N; Bouchiba, H; Briolant, S; Desbordes, M; Marin-Jauffre, A; Martelloni, M; Pascual, A; Pommier de Santi, V; Pradines, B; Richa, G; Taudon, N; Wurtz, N	1
Becher, G; Wylie, G	1
Ariey, F; Bjorge, S; Chea, N; Christophel, EM; Duong, S; Habib, N; Hoyer, S; Kheng, S; Khim, N; Kim, S; Mellor, S; Menard, D; Newman, RD; Nguon, S; Ros, S; Sophal, U; Sum, S; Thompson, MM; Thomson, A; Top, S; Witkowski, B; Yeang, C; Yeung, S; Yok, S	1
Borrmann, S; Erkens, MA; Graumans, W; Heinrichs, MJ; Hermsen, CC; Hoffman, SL; Luty, AJ; Nganou-Makamdop, K; Roestenberg, M; Rozier, YP; Sauerwein, RW; Scholzen, A; Siebelink-Stoter, R; Sim, BK; Teelen, K; Teirlinck, AC; van de Vegte-Bolmer, M; van Gemert, GJ; van Lieshout, L; Visser, LG; Vos, MW	1
Abong'o, D; Bayoh, MN; Desai, M; Gimnig, JE; Hamel, MJ; Kariuki, S; Kosgei, J; Lobo, NF; Marwanga, D; Olang, G; Ombok, M; Otieno, P; Vulule, J; Walker, ED; Williamson, J	1
Kaiser, A; Maier, W	1
Sehdev, PS	1
Baird, JK; Bangs, MJ; Barcus, MJ; Chulay, JD; Fryauff, DJ; Gramzinski, R; Hoffman, SL; Jones, TR; Kumusumangsih, M; Lacy, M; Ling, J; Maguire, JD; Miller, GB; Sismadi, P	1
Schau, A; Winkler, C; Ziegler, T	1
Fourcade, L; Heno, P; Hovette, P; Paule, P; Pradines, B; Touze, JE	1
Camus, D; Delhaes, L; Dutoit, E; Inglebert, P; Masson, V	1
Djossou, F; Etienne, G; Le Bras, M; Longy-Boursier, M; Malvy, D; Pistone, T; Vatan, R	1
Delmont, J	2
Baird, JK; Bangs, MJ; Barcus, MJ; Basri, H; Chulay, JD; Fryauff, DJ; Gramzinski, R; Hoffman, SL; Lacy, MD; Ling, J; Maguire, JD; Miller, GB; Sismadi, P	1
Brockman, A; Leonardi, E; Looareesuwan, S; McGready, R; Nosten, F; Phaipun, L; Slight, T; Thway, KL; van Vugt, M; Villegas, L; White, NJ	1
Butcher, GA; Sinden, RE	1
Berezcky, S; Berqvist, Y; Björkman, A; Färnert, A; Gil, P; Lindberg, J; Lindegårdh, N; Swedberg, G; Thapar, MM	1
McKeage, K; Scott, L	1
Alifrangis, M; Jelinek, T; Salanti, A; Schwöbel, B	1
Bricaire, F; Danis, M	1
Dupouy-Camet, J; Tourte-Schaeffer, C; Yera, H	1
Kain, KC	1
Crabb, C	1
Bujanover, S; Kain, KC; Schwartz, E	1
Ensom, MH; Marra, F; Salzman, JR	1
Cho, T; Edstein, MD; Gilveray, G; Looareesuwan, S; McGready, R; Nosten, F; Stepniewska, K; White, NJ	1
Basco, LK	1
Binh, TQ; De Vries, PJ; Giao, PT; Hung, LQ; Kager, PA; Nam, NV	1
Fischer, PR; Stauffer, W	1
Bagaphou, T; Binder, RK; Borrmann, S; Faucher, JF; Kremsner, PG; Lell, B; Matsiegui, PB; Miller, G; Missinou, MA; Pabisch, S; Rezbach, P	1
Alifrangis, M; Bygbjerg, IB; David, KP; Rønn, A; Salanti, A; Vestergaard, LS	1
Bienzle, U; Ehrhardt, S; Jelinek, T; Mockenhaupt, FP; Muehlen, M; Otchwemah, R; Schreiber, J	1
Binh, TQ; de Vries, PJ; Giao, PT; Hung, le Q; Kager, PA; Nam, NV	1
Gruss, H; Jelinek, T; Mockenhaupt, FP; Muehlen, M; Suttorp, N; Wichmann, O	1
Arizono, N; Kajita, Y; Murakami, S; Okamoto, A; Sato, K; Tegoshi, T; Uchiyama, H; Yamada, T; Yoneda, S	1
Alifrangis, M; Beran, J; Bisoffi, Z; Cuadros, J; da Cunha, S; Ehrhardt, S; Fry, G; Gascon, J; Gjorup, I; Grobusch, MP; Hatz, C; Jelinek, T; Kern, P; Kollaritsch, H; Laferl, H; Matteelli, A; McWhinney, P; Muehlberger, N; Muhlen, M; Peyerl-Hoffmann, G; Richter, J; Schulze, M; Wichmann, O	1
Björkman, A; Gil, JP; Thapar, MM	1
Ayuo, PO; Esamai, F; Jakait, B; Obala, A; Ong'or, WO; Tenge, CN	1
Gill, MJ; Kain, KC; Kuhn, S	1
Kioy, D; Konsil, J; Manyando, C; Miller, GB; Mulenga, M; Na-Bangchang, K; Ruengweerayut, R	1
Ashley, EA; Barends, M; Cho, T; Hutagalung, R; Looareesuwan, S; McGready, R; Moo, E; Nosten, F; White, NJ	1
Gupta, RK; Looareesuwan, S; Nosten, F; Paiphun, L; Slight, T; Van Vugt, M; White, NJ	1
Anderson, KL; Edstein, MD; Good, MF; Kotecka, BM; Kyle, DE; Pombo, DJ; Rieckmann, KH	1
Petersen, JE	1
Orton, L; Osei-Akoto, A; Owusu-Ofori, SP	1
Kain, KC; Patel, SN	1
Bigot, P; Durand, R; Le Bras, J; Musset, L; Parzy, D; Pradines, B	1
Cho, T; Gilveray, G; Looareesuwan, S; McGready, R; Nosten, F; Stepniewska, K; Ward, SA; White, NJ	1
Benchimol, C; Bernardino, L; Bom, J; do Rosário, V; Nogueira, F; Pimentel, S; Quinhentos, V; Varandas, L	1
Bourée, P	1
Benoit-Vical, F; Berry, A; Fabre, R; Lelièvre, J; Magnaval, JF; Marchou, B; Senescau, A	1
Berzins, K; Grandien, A; Hagstedt, M; Nyakeriga, AM; Perlmann, H; Perlmann, P; Troye-Blomberg, M; Zhivotovsky, B	1
Bennett, S; Fielding, K; Greenwood, B; Malunga, P; Mulenga, M; Shulman, C; Thuma, P	1
Bouchaud, O; Le Bras, J; Massias, L; Matheron, S; Musset, L	1
Folarin, OA; Gbotosho, GO; Happi, CT; Kyle, DE; Milhous, WK; Milner, D; Oduola, AM; Sarr, O; Sowunmi, A; Wirth, DF	1
Alloueche, A; Bennett, S; Fielding, K; Greenwood, BM; Malunga, F; Mulenga, M; Shulman, C; Thuma, PE	1
Hitani, A; Kimura, M; Nakamura, T; Nawa, Y; Ohtomo, H	1
Boggild, AK; Kain, KC; Lewis, LS; Parise, ME	1
Iwagami, M; Kano, S; Kawazu, S; Looareesuwan, S; Naoshima-Ishibashi, Y	1
Boggild, AK; Kain, KC; Krudsood, S; Leowattana, W; Looareesuwan, S; Patel, SN; Pornpininworakij, K; Tangpukdee, N; Thanachartwet, W	1
Bouchier, C; Carme, B; Demar, M; Ekala, MT; Esterre, P; Fandeur, T; Legrand, E; Puijalon, OM; Quinternet, M; Rogier, C; Volney, B	1
Clain, J; Le Bras, J; Musset, L	1
Burgner, D; Cherian, S	1
Kessl, JJ; Meshnick, SR; Trumpower, BL	1
Ansari, MJ; Garapati, S; Iroegbu, N; Okoli, O; Spear, JB; Wongba, W	1
Exner, B; Kollaritsch, H; Rojanawatsirivet, C; Sirichaisinthop, J; Wernsdorfer, G; Wernsdorfer, WH	1
Kollaritsch, H; Noedl, H; Parizek, M; Sirichaisinthop, J; Wernsdorfer, G; Wernsdorfer, WH	1
Khositnithikul, R; Mungthin, M; Tan-Ariya, P	1
Bouchaud, O; Cailhol, J; Durand, R; Hubert, V; Le Bras, J; Massias, L; Prendki, V; Ralaimazava, P	1
Ballou, WR; Heppner, DG; Lievens, M; Ogutu, B; Polhemus, ME; Remich, S; Waitumbi, J	1
Angoulvant, F; Bigirimana, Z; Blondé, R; Bourdon, O; Bourrillon, A; D'Ortenzio, E; Faye, A; Fenneteau, O; Holvoet, L; Le Bras, J; Lorrot, M; Matheron, S; Naudin, J; Vitoux, C	1
Kain, KC; Le Saux, N; McCarthy, AE; Rose, GW; Suh, KN	1
Ager, AL; Canfield, CJ; Jacobus, DP; Lewis, NJ; Milhous, WK; Rossan, RN; Sweeney, TR	1
Canfield, CJ; Hutchinson, DB; Kyle, DE; Looareesuwan, S; Viravan, C; Webster, HK	1
Hutchinson, D; Kremsner, PG; Nkeyi, M; Philipps, J; Radloff, PD	1
Birley, H; Chiodini, PL; Conlon, CP; Farquhar, JA; Hall, AP; Hutchinson, DB; Peto, TE; Warrell, DA	1
Canfield, CJ; Eaves, CJ; Hussein, Z; Hutchinson, DB	1
Canfield, CJ; Eaves, J; Hussein, Z; Hutchinson, DB	1
Yeo, AE	1
Edstein, MD; Rieckmann, KH; Yeo, AE	1
Edstein, MD; Kyle, DE; Looareesuwan, S; Viravan, C	1
Basco, LK; Ringwald, P	1
Fourcade, L; Touze, JE	1
Aleman, GM; Gordon, DM; Klotz, FW; Oloo, AJ; Sadie, D; Scott, TR; Shanks, GD	1
Whitty, CJ	1
Bustos, DG; Canete-Miguel, E; Canfield, CJ; Hutchinson, DB	1
Barditch-Crovo, P; Kumar, N; Ranasinha, CD; Shapiro, TA	1
Chisdaka, N; Mulenga, M; Roskell, NS; Scott, TR; Sukwa, TY	1
Canfield, CJ; Chalermarut, K; Hutchinson, DB; Looareesuwan, S; Rattanapong, Y; Wilairatana, P	1
Canfield, CJ; Chulay, JD; Hutchinson, DB; Looareesuwan, S	1
Anabwani, G; Canfield, CJ; Hutchinson, DB	1
Duvenage, CS; Roskell, NS; Scott, TR; van der Berg, JD	1
White, N	1
Watt, G	1
Dragsted, UB; Lundgren, JD	1
Nosten, F	1
Camus, D; Chulay, JD; Clarke, PD; Günther, M; Høgh, B; Joubert, I; Kain, KC; Nothdurft, HD; Overbosch, D; Roskell, NS; Shaw, D	1
Brugha, R; Shretta, R; Snow, R; Walt, G	1
Kain, KC; Keystone, JS; Shanks, GD	1
Beck, B; Blum, J; Funk, M; Furrer, H; Genton, B; Hatz, FR; Holzer, B; Loutan, L; Markwalder, K; Raeber, PA; Schlagenhauf, P; Siegl, G; Steffen, R; Stürchler, D; Wyss, R	1
Campos, P; Canfield, CJ; Clendenes, M; Hutchinson, DB; Llanos-Cuentas, A	1
Baird, JK; Bangs, MJ; Barcus, MJ; Basri, H; Fryauff, DJ; Gramzinski, R; Hoffman, SL; Jones, TR; Kusumaningsih, M; Lacy, MD; Ling, J; Maguire, JD; Sismadi, P; Wiady, I	1
World, MJ	1
Gatton, ML; Hogarth, W; Saul, A	1
Adagu, IS; Butcher, GA; Fivelman, QL; Pasvol, G; Warhurst, DC	1
Dickins, M; Ginger, CD; Gutteridge, WE; Holdich, T; Hudson, AT; Hutchinson, DB; Latter, VS; Pudney, M; Randall, AW	1

Reviews

32 review(s) available for atovaquone and Malaria, Falciparum

Article	Year
Using genetic methods to define the targets of compounds with antimalarial activity. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum	2013
Antimalarial application of quinones: A recent update. European journal of medicinal chemistry, 2021, Jan-15, Volume: 210 Topics: Antimalarials; Dose-Response Relationship, Drug; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinones; Structure-Activity Relationship	2021
Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis. The Lancet. Infectious diseases, 2020, Volume: 20, Issue:8 Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clindamycin; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine	2020
Atovaquone-proguanil for treating uncomplicated Plasmodium falciparum malaria. The Cochrane database of systematic reviews, 2021, 01-15, Volume: 1 Topics: Adult; Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Atovaquone; Cameroon; Child; Colombia; Drug Combinations; Ethiopia; Humans; Malaria, Falciparum; Mefloquine; Proguanil; Randomized Controlled Trials as Topic; Thailand; Treatment Failure	2021
Mefloquine for preventing malaria during travel to endemic areas. The Cochrane database of systematic reviews, 2017, 10-30, Volume: 10 Topics: Adult; Antimalarials; Atovaquone; Child; Chloroquine; Doxycycline; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Primaquine; Proguanil; Randomized Controlled Trials as Topic; Travel-Related Illness	2017
Clinical implications of Plasmodium resistance to atovaquone/proguanil: a systematic review and meta-analysis. The Journal of antimicrobial chemotherapy, 2018, 03-01, Volume: 73, Issue:3 Topics: Atovaquone; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Electron Transport Complex III; Humans; Malaria, Falciparum; Malaria, Vivax; Mutation; Plasmodium falciparum; Proguanil; Travel; Treatment Failure	2018
Clinical pharmacology of atovaquone and proguanil hydrochloride. Journal of travel medicine, 1999, Volume: 6 Suppl 1 Topics: Animals; Antimalarials; Atovaquone; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Activation; Humans; Intestinal Absorption; Intestinal Mucosa; Lymphocytes; Malaria; Malaria, Falciparum; Malaria, Vivax; Proguanil	1999
Atovaquone and proguanil hydrochloride for treatment of malaria. Journal of travel medicine, 1999, Volume: 6 Suppl 1 Topics: Antimalarials; Atovaquone; Chemoprevention; Drug Combinations; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Travel	1999
Atovaquone and proguanil hydrochloride for prophylaxis of malaria. Journal of travel medicine, 1999, Volume: 6 Suppl 1 Topics: Animals; Antimalarials; Atovaquone; Chemoprevention; Drug Combinations; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Randomized Controlled Trials as Topic; Travel; Treatment Outcome	1999
WITHDRAWN: Drugs for preventing malaria in travellers. The Cochrane database of systematic reviews, 2015, Oct-05, Issue:10 Topics: Adult; Antimalarials; Atovaquone; Child; Chloroquine; Doxycycline; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Primaquine; Proguanil; Randomized Controlled Trials as Topic; Travel	2015
Drugs for preventing malaria in travellers. The Cochrane database of systematic reviews, 2009, Oct-07, Issue:4 Topics: Adult; Antimalarials; Atovaquone; Child; Chloroquine; Doxycycline; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Primaquine; Proguanil; Randomized Controlled Trials as Topic; Travel	2009
Azithromycin for treating uncomplicated malaria. The Cochrane database of systematic reviews, 2011, Feb-16, Issue:2 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Atovaquone; Azithromycin; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Proguanil; Pyrimethamine; Randomized Controlled Trials as Topic; Sulfadoxine; Treatment Failure	2011
[New strategies in therapy to roll back malaria]. Deutsche medizinische Wochenschrift (1946), 2002, Jul-26, Volume: 127, Issue:30 Topics: Antimalarials; Atovaquone; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Malaria, Falciparum; Metabolic Clearance Rate; Naphthoquinones; Proguanil; Risk Factors; Travel	2002
Atovaquone/proguanil for plasmodium falciparum malaria. The Pediatric infectious disease journal, 2002, Volume: 21, Issue:8 Topics: Animals; Antimalarials; Atovaquone; Controlled Clinical Trials as Topic; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Proguanil	2002
[Value of malarone in therapy of malaria tropica]. Medizinische Klinik (Munich, Germany : 1983), 2002, Aug-15, Volume: 97, Issue:8 Topics: Animals; Antimalarials; Atovaquone; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Proguanil; Randomized Controlled Trials as Topic	2002
[Mechanism of action of antimalarials. Value of combined atovaquone/proguanil]. Medecine tropicale : revue du Corps de sante colonial, 2002, Volume: 62, Issue:3 Topics: Animals; Antimalarials; Atovaquone; DNA Replication; DNA, Protozoan; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mitochondria; Naphthoquinones; Organelles; Plasmodium falciparum; Proguanil	2002
[Clinical studies using the combination atovaquone-proguanil as malaria prophylaxis in non-immune adult and child travelers]. Medecine tropicale : revue du Corps de sante colonial, 2002, Volume: 62, Issue:3 Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Child; Humans; Malaria, Falciparum; Middle Aged; Naphthoquinones; Patient Compliance; Proguanil; Travel	2002
[What is the value of the combination atovaquone-proguanil for the clinician?]. Medecine tropicale : revue du Corps de sante colonial, 2002, Volume: 62, Issue:3 Topics: Animals; Antimalarials; Atovaquone; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Proguanil; Travel	2002
Atovaquone/proguanil: a review of its use for the prophylaxis of Plasmodium falciparum malaria. Drugs, 2003, Volume: 63, Issue:6 Topics: Animals; Antimalarials; Atovaquone; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil; Travel	2003
The new drug combinations: their place in the treatment of uncomplicated Plasmodium falciparum malaria. Fundamental & clinical pharmacology, 2003, Volume: 17, Issue:2 Topics: Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Drug Resistance, Multiple; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Naphthoquinones; Proguanil; Sesquiterpenes	2003
Current status and replies to frequently posed questions on atovaquone plus proguanil (Malarone) for the prevention of malaria. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2003, Volume: 17 Suppl 1 Topics: Antimalarials; Atovaquone; Drug Administration Schedule; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil; Randomized Controlled Trials as Topic; Travel	2003
Atovaquone-proguanil for prophylaxis and treatment of malaria. The Annals of pharmacotherapy, 2003, Volume: 37, Issue:9 Topics: Antimalarials; Atovaquone; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil	2003
[Malaria chemoprophylaxis]. Ugeskrift for laeger, 2005, Oct-17, Volume: 167, Issue:42 Topics: Antimalarials; Atovaquone; Chloroquine; Contraindications; Doxycycline; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Mefloquine; Naphthoquinones; Practice Guidelines as Topic; Pregnancy; Proguanil; Risk Assessment; Travel	2005
Atovaquone-proguanil for treating uncomplicated malaria. The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4 Topics: Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil; Randomized Controlled Trials as Topic	2005
Atovaquone/proguanil for the prophylaxis and treatment of malaria. Expert review of anti-infective therapy, 2005, Volume: 3, Issue:6 Topics: Animals; Atovaquone; Drug Therapy, Combination; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil	2005
Modeling the molecular basis of atovaquone resistance in parasites and pathogenic fungi. Trends in parasitology, 2007, Volume: 23, Issue:10 Topics: Amino Acid Sequence; Animals; Anti-Infective Agents; Atovaquone; Electron Transport Complex III; Enzyme Inhibitors; Humans; Malaria, Falciparum; Models, Molecular; Molecular Sequence Data; Plasmodium falciparum; Pneumocystis carinii; Pneumonia, Pneumocystis; Sequence Alignment; Toxoplasma; Toxoplasmosis; Yeasts	2007
[Malarone: newcomer in the treatment of malaria]. Medecine tropicale : revue du Corps de sante colonial, 1997, Volume: 57, Issue:3 Topics: Antimalarials; Atovaquone; Chloroquine; Clinical Trials, Phase III as Topic; Drug Combinations; Drug Resistance; Drug Tolerance; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil	1997
Malarone (atovaquone and proguanil hydrochloride): a review of its clinical development for treatment of malaria. Malarone Clinical Trials Study Group. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:4 Topics: Adult; Aged; Antimalarials; Atovaquone; Child; Drug Combinations; Drug Therapy, Combination; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil; Randomized Controlled Trials as Topic	1999
[Atovaquone/proguanil. Prophylaxis and treatment of malaria]. Ugeskrift for laeger, 2000, Jul-31, Volume: 162, Issue:31 Topics: Antimalarials; Atovaquone; Chloroquine; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil	2000
Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jul-15, Volume: 33, Issue:2 Topics: Animals; Antimalarials; Atovaquone; Azithromycin; Chloroquine; Drug Resistance; Health Planning Guidelines; Humans; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Primaquine; Proguanil	2001
[Malaria--chemoprophylaxis 2001]. Therapeutische Umschau. Revue therapeutique, 2001, Volume: 58, Issue:6 Topics: Africa; Antimalarials; Asia; Atovaquone; Chloroquine; Contraindications; Doxycycline; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Mefloquine; Naphthoquinones; Practice Guidelines as Topic; Proguanil; South America; Switzerland; Travel	2001
[symbol: see text] Atovaquone + proguanil for malaria prophylaxis. Drug and therapeutics bulletin, 2001, Volume: 39, Issue:10 Topics: Antimalarials; Atovaquone; Drug Administration Schedule; Drug Combinations; Endemic Diseases; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil; Travel	2001

Trials

38 trial(s) available for atovaquone and Malaria, Falciparum

Article	Year
Unanticipated CNS Safety Signal in a Placebo-Controlled, Randomized Trial of Co-Administered Atovaquone-Proguanil and Amodiaquine. Clinical pharmacology and therapeutics, 2022, Volume: 111, Issue:4 Topics: Amodiaquine; Antimalarials; Atovaquone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria; Malaria, Falciparum; Male; Proguanil; Treatment Outcome	2022
Inhibition of merozoite invasion and transient de-sequestration by sevuparin in humans with Plasmodium falciparum malaria. PloS one, 2017, Volume: 12, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Aged; Antimalarials; Area Under Curve; Atovaquone; Binding, Competitive; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Erythrocytes; Female; Heparin; Heparitin Sulfate; Humans; Infusions, Intravenous; Malaria, Falciparum; Male; Merozoites; Middle Aged; Parasite Load; Parasitemia; Plasmodium falciparum; Proguanil; Severity of Illness Index	2017
Randomized trial of artesunate-amodiaquine, atovaquone-proguanil, and artesunate-atovaquone-proguanil for the treatment of uncomplicated falciparum malaria in children. The Journal of infectious diseases, 2014, Dec-15, Volume: 210, Issue:12 Topics: Amodiaquine; Antimalarials; Artemisinins; Atovaquone; Cameroon; Child, Preschool; Cytochromes b; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Treatment Outcome	2014
Pharmacokinetic evaluation of intravenous artesunate in adults with uncomplicated falciparum malaria in Kenya: a phase II study. Malaria journal, 2014, Jul-22, Volume: 13 Topics: Activation, Metabolic; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Atovaquone; Chromatography, Liquid; Drug Combinations; Drug Compounding; Drug Monitoring; Female; Half-Life; Humans; Infusions, Intravenous; Kenya; Malaria, Falciparum; Male; Mass Spectrometry; Middle Aged; Proguanil; Reticulocytes; Young Adult	2014
Ototoxicity of artemether/lumefantrine in the treatment of falciparum malaria: a randomized trial. Malaria journal, 2008, Sep-16, Volume: 7 Topics: Adolescent; Adult; Artemether; Artemisinins; Atovaquone; Audiometry; Child; Ethanolamines; Ethiopia; Female; Fluorenes; Hearing Loss, Sensorineural; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Proguanil; Quinine	2008
Use of peroxisome proliferator-activated receptor gamma agonists as adjunctive treatment for Plasmodium falciparum malaria: a randomized, double-blind, placebo-controlled trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Sep-15, Volume: 49, Issue:6 Topics: Adjuvants, Immunologic; Adolescent; Adult; Animals; Antimalarials; Atovaquone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Immunity, Innate; Inflammation; Inflammation Mediators; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; PPAR gamma; Proguanil; Rosiglitazone; Thailand; Thiazolidinediones; Time Factors; Treatment Outcome; Young Adult	2009
Prolonged protection provided by a single dose of atovaquone-proguanil for the chemoprophylaxis of Plasmodium falciparum malaria in a human challenge model. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Jan-15, Volume: 54, Issue:2 Topics: Adult; Antimalarials; Area Under Curve; Atovaquone; Chemoprevention; Cohort Studies; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Placebos; Plasmodium falciparum; Proguanil; Sporozoites	2012
Randomized, prospective, three-arm study to confirm the auditory safety and efficacy of artemether-lumefantrine in Colombian patients with uncomplicated Plasmodium falciparum malaria. The American journal of tropical medicine and hygiene, 2012, Volume: 86, Issue:1 Topics: Adolescent; Adult; Aged; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Atovaquone; Audiometry; Child; Colombia; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Evoked Potentials, Auditory, Brain Stem; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Proguanil; Prospective Studies; Treatment Outcome; Young Adult	2012
NF135.C10: a new Plasmodium falciparum clone for controlled human malaria infections. The Journal of infectious diseases, 2013, Feb-15, Volume: 207, Issue:4 Topics: Adolescent; Adult; Animals; Anopheles; Antimalarials; Atovaquone; Genotype; Humans; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Proguanil; Treatment Outcome; Young Adult	2013
Randomized, placebo-controlled trial of atovaquone/proguanil for the prevention of Plasmodium falciparum or Plasmodium vivax malaria among migrants to Papua, Indonesia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Oct-01, Volume: 35, Issue:7 Topics: Adolescent; Adult; Animals; Antimalarials; Atovaquone; Chemoprevention; Child; Double-Blind Method; Female; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Naphthoquinones; Patient Compliance; Plasmodium falciparum; Plasmodium vivax; Proguanil; Transients and Migrants; Treatment Outcome	2002
Atovaquone/proguanil therapy for Plasmodium falciparum and Plasmodium vivax malaria in Indonesians who lack clinical immunity. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Nov-01, Volume: 35, Issue:9 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Atovaquone; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Indonesia; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Naphthoquinones; Plasmodium falciparum; Plasmodium vivax; Proguanil; Treatment Outcome	2002
Treatment of uncomplicated multidrug-resistant falciparum malaria with artesunate-atovaquone-proguanil. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Dec-15, Volume: 35, Issue:12 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Child; Child, Preschool; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Plasmodium falciparum; Proguanil; Sesquiterpenes; Treatment Failure	2002
The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria. European journal of clinical pharmacology, 2003, Volume: 59, Issue:7 Topics: Acute Disease; Antimalarials; Artemisinins; Artesunate; Atovaquone; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Naphthoquinones; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Proguanil; Sesquiterpenes; Thailand	2003
Atovaquone and proguanil versus amodiaquine for the treatment of Plasmodium falciparum malaria in African infants and young children. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Dec-01, Volume: 37, Issue:11 Topics: Amodiaquine; Animals; Antimalarials; Atovaquone; Child; Drug Combinations; Drug Tolerance; Female; Humans; Infant; Malaria, Falciparum; Male; Naphthoquinones; Proguanil; Treatment Outcome	2003
CV8, a new combination of dihydroartemisinin, piperaquine, trimethoprim and primaquine, compared with atovaquone-proguanil against falciparum malaria in Vietnam. Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:2 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Atovaquone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Primaquine; Proguanil; Quinolines; Sesquiterpenes; Treatment Outcome; Trimethoprim; Vietnam	2004
A randomized open label clinical trial to compare the efficacy and safety of intravenous quinine followed by oral malarone vs. intravenous quinine followed by oral quinine in the treatment of severe malaria. Journal of tropical pediatrics, 2005, Volume: 51, Issue:1 Topics: Administration, Oral; Adolescent; Adult; Atovaquone; Child; Child, Preschool; Developing Countries; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Kenya; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Prognosis; Proguanil; Quinine; Risk Assessment; Severity of Illness Index; Single-Blind Method; Survival Analysis; Treatment Outcome	2005
The pharmacokinetics and pharmacodynamics of atovaquone and proguanil for the treatment of uncomplicated falciparum malaria in third-trimester pregnant women. European journal of clinical pharmacology, 2005, Volume: 61, Issue:8 Topics: Adolescent; Adult; Antimalarials; Atovaquone; Drug Combinations; Female; Humans; Malaria, Falciparum; Naphthoquinones; Pregnancy; Proguanil; Thailand; Triazines; Zambia	2005
A randomized comparison of artesunate-atovaquone-proguanil versus quinine in treatment for uncomplicated falciparum malaria during pregnancy. The Journal of infectious diseases, 2005, Sep-01, Volume: 192, Issue:5 Topics: Adolescent; Adult; Anemia; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Female; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Naphthoquinones; Parasitemia; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Proguanil; Quinine; Sesquiterpenes; Thailand	2005
Short report: no evidence of cardiotoxicity of atovaquone-proguanil alone or in combination with artesunate. The American journal of tropical medicine and hygiene, 2005, Volume: 73, Issue:2 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Child; Drug Therapy, Combination; Electrocardiography; Female; Heart Diseases; Humans; Long QT Syndrome; Malaria, Falciparum; Male; Middle Aged; Myanmar; Myocardium; Naphthoquinones; Plasmodium falciparum; Proguanil; Sesquiterpenes; Thailand; Treatment Outcome	2005
Folic acid treatment of Zambian children with moderate to severe malaria anemia. The American journal of tropical medicine and hygiene, 2006, Volume: 74, Issue:6 Topics: Anemia; Animals; Antimalarials; Atovaquone; Child; Child, Preschool; Drug Combinations; Folic Acid; Hematinics; Humans; Infant; Malaria, Falciparum; Naphthoquinones; Parasitemia; Population Density; Proguanil; Pyrimethamine; Sulfadoxine; Treatment Failure; Zambia	2006
A randomised, double-blind, placebo-controlled trial of atovaquone-proguanil vs. sulphadoxine-pyrimethamine in the treatment of malarial anaemia in Zambian children. Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:11 Topics: Anemia; Antimalarials; Atovaquone; Child; Child, Preschool; Double-Blind Method; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Prevalence; Proguanil; Pyrimethamine; Sulfadoxine; Time Factors; Treatment Failure; Zambia	2006
Efficacy of atovaquone-proguanil for treatment of acute multidrug-resistant Plasmodium falciparum malaria in Thailand. The American journal of tropical medicine and hygiene, 2007, Volume: 76, Issue:4 Topics: Adolescent; Adult; Animals; Antimalarials; Atovaquone; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Proguanil; Thailand	2007
Malaria treatment with atovaquone-proguanil in malaria-immune adults: implications for malaria intervention trials and for pre-exposure prophylaxis of malaria. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4 Topics: Adolescent; Adult; Animals; Antimalarials; Atovaquone; Chemoprevention; Humans; Kaplan-Meier Estimate; Kenya; Malaria Vaccines; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Proguanil; Time Factors	2008
Atovaquone and proguanil for Plasmodium falciparum malaria. Lancet (London, England), 1996, Jun-01, Volume: 347, Issue:9014 Topics: Acute Disease; Adult; Amodiaquine; Antimalarials; Atovaquone; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Gabon; Humans; Malaria, Falciparum; Male; Naphthoquinones; Proguanil; Time Factors; Treatment Outcome	1996
Evaluation of atovaquone in the treatment of patients with uncomplicated Plasmodium falciparum malaria. The Journal of antimicrobial chemotherapy, 1995, Volume: 36, Issue:6 Topics: Adult; Antimalarials; Atovaquone; Dose-Response Relationship, Drug; Drug Administration Schedule; Evaluation Studies as Topic; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Treatment Outcome	1995
Population pharmacokinetics of proguanil in patients with acute P. falciparum malaria after combined therapy with atovaquone. British journal of clinical pharmacology, 1996, Volume: 42, Issue:5 Topics: Acute Disease; Adolescent; Adult; Aged; Antimalarials; Atovaquone; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Proguanil	1996
Population pharmacokinetics of atovaquone in patients with acute malaria caused by Plasmodium falciparum. Clinical pharmacology and therapeutics, 1997, Volume: 61, Issue:5 Topics: Adolescent; Adult; Analysis of Variance; Antimalarials; Atovaquone; Child; Child, Preschool; Computer Simulation; Databases, Factual; Dose-Response Relationship, Drug; Female; Gabon; Humans; Kenya; Malaria, Falciparum; Male; Middle Aged; Models, Biological; Naphthoquinones; Philippines; Thailand; Zambia	1997
Pharmacokinetics of proguanil in malaria patients treated with proguanil plus atovaquone. The Southeast Asian journal of tropical medicine and public health, 1996, Volume: 27, Issue:2 Topics: Acute Disease; Adolescent; Adult; Antimalarials; Atovaquone; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Synergism; Drug Therapy, Combination; Humans; Intestinal Absorption; Malaria, Falciparum; Male; Metabolic Clearance Rate; Naphthoquinones; Proguanil	1996
Efficacy and safety of atovaquone/proguanil as suppressive prophylaxis for Plasmodium falciparum malaria. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:3 Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; Female; Humans; Kenya; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitemia; Proguanil; Treatment Outcome	1998
Atovaquone-proguanil compared with chloroquine and chloroquine-sulfadoxine-pyrimethamine for treatment of acute Plasmodium falciparum malaria in the Philippines. The Journal of infectious diseases, 1999, Volume: 179, Issue:6 Topics: Antimalarials; Atovaquone; Chloroquine; Drug Therapy, Combination; Folic Acid Antagonists; Humans; Malaria, Falciparum; Naphthoquinones; Philippines; Proguanil; Pyrimethamine; Sulfadoxine	1999
Prophylactic activity of atovaquone against Plasmodium falciparum in humans. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:5 Topics: Adolescent; Adult; Animals; Anopheles; Antimalarials; Atovaquone; Double-Blind Method; Humans; Insect Bites and Stings; Malaria, Falciparum; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Polymerase Chain Reaction	1999
A randomized, double-blind, placebo-controlled field trial to determine the efficacy and safety of Malarone (atovaquone/proguanil) for the prophylaxis of malaria in Zambia. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:4 Topics: Adolescent; Adult; Animals; Antimalarials; Atovaquone; Double-Blind Method; Drug Combinations; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Proguanil; Zambia	1999
Efficacy and safety of atovaquone/proguanil compared with mefloquine for treatment of acute Plasmodium falciparum malaria in Thailand. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:4 Topics: Acute Disease; Adolescent; Adult; Antimalarials; Atovaquone; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Naphthoquinones; Proguanil; Thailand; Treatment Outcome	1999
Combination atovaquone and proguanil hydrochloride vs. halofantrine for treatment of acute Plasmodium falciparum malaria in children. The Pediatric infectious disease journal, 1999, Volume: 18, Issue:5 Topics: Acute Disease; Animals; Antimalarials; Atovaquone; Child; Child, Preschool; Drug Therapy, Combination; Feces; Female; Humans; Malaria, Falciparum; Male; Naphthoquinones; Phenanthrenes; Plasmodium falciparum; Proguanil; Treatment Outcome	1999
Safety and efficacy of atovaquone and proguanil hydrochloride for the prophylaxis of Plasmodium falciparum malaria in South Africa. Clinical therapeutics, 1999, Volume: 21, Issue:4 Topics: Adult; Antimalarials; Atovaquone; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Proguanil; South Africa	1999
Atovaquone-proguanil versus chloroquine-proguanil for malaria prophylaxis in non-immune travellers: a randomised, double-blind study. Malarone International Study Team. Lancet (London, England), 2000, Dec-02, Volume: 356, Issue:9245 Topics: Adolescent; Adult; Aged; Antimalarials; Anxiety; Atovaquone; Chloroquine; Dizziness; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Gastrointestinal Diseases; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Proguanil; Travel; Treatment Outcome	2000
Atovaquone and proguani hydrochloride compared with chloroquine or pyrimethamine/sulfodaxine for treatment of acute Plasmodium falciparum malaria in Peru. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases, 2001, Volume: 5, Issue:2 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Atovaquone; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Microbial Sensitivity Tests; Middle Aged; Naphthoquinones; Peru; Proguanil; Pyrimethamine; Sulfadoxine; Treatment Outcome	2001
Randomized, parallel placebo-controlled trial of primaquine for malaria prophylaxis in Papua, Indonesia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Dec-15, Volume: 33, Issue:12 Topics: Adolescent; Adult; Animals; Antimalarials; Atovaquone; Chemoprevention; Child; Drug Combinations; Female; Humans; Indonesia; Malaria, Falciparum; Male; Methemoglobinemia; Middle Aged; Naphthoquinones; Patient Compliance; Plasmodium falciparum; Primaquine; Proguanil; Treatment Outcome	2001

Other Studies

155 other study(ies) available for atovaquone and Malaria, Falciparum

Article	Year
High-throughput Plasmodium falciparum growth assay for malaria drug discovery. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2 Topics: Animals; Biological Assay; Child, Preschool; DNA, Protozoan; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Female; Humans; Indoles; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Pregnancy	2007
First case of emergence of atovaquone-proguanil resistance in Plasmodium falciparum during treatment in a traveler in Comoros. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Animals; Antimalarials; Atovaquone; Comoros; Drug Resistance; France; Genotype; Humans; Malaria, Falciparum; Male; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Travel; Treatment Failure	2008
Synthesis and antimalarial activity of new atovaquone derivatives. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Antimalarials; Atovaquone; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2009
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections. Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21 Topics: Alkynes; Antimalarials; Binding Sites; Cell Line, Tumor; Computer Simulation; Erythrocytes; Fatty Acid Synthase, Type II; Fatty Acids, Unsaturated; Humans; Kinetics; Liver; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins	2010
Lead optimization of 3-carboxyl-4(1H)-quinolones to deliver orally bioavailable antimalarials. Journal of medicinal chemistry, 2012, May-10, Volume: 55, Issue:9 Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Female; Hep G2 Cells; Humans; Malaria, Falciparum; Mice; Mice, Inbred ICR; Nuclear Magnetic Resonance, Biomolecular; Parasitemia; Plasmodium falciparum; Quinolines; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship	2012
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds. Proceedings of the National Academy of Sciences of the United States of America, 2012, May-29, Volume: 109, Issue:22 Topics: Animals; Anopheles; Antimalarials; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Inhibitory Concentration 50; Insect Vectors; Life Cycle Stages; Liver; Malaria; Malaria, Falciparum; Male; Mice; Mice, Inbred C57BL; Plasmodium berghei; Plasmodium falciparum; Treatment Outcome	2012
Addition of thiols to o-quinone methide: new 2-hydroxy-3-phenylsulfanylmethyl[1,4]naphthoquinones and their activity against the human malaria parasite Plasmodium falciparum (3D7). European journal of medicinal chemistry, 2013, Volume: 59 Topics: Antimalarials; Cells, Cultured; Flow Cytometry; Humans; Indolequinones; Malaria, Falciparum; Molecular Structure; Naphthoquinones; Plasmodium falciparum; Sulfhydryl Compounds	2013
Aminoazabenzimidazoles, a novel class of orally active antimalarial agents. Journal of medicinal chemistry, 2014, Jul-10, Volume: 57, Issue:13 Topics: Animals; Antimalarials; Benzimidazoles; Biological Availability; Cell Line, Tumor; Cell Survival; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mice; Plasmodium falciparum; Small Molecule Libraries; Structure-Activity Relationship	2014
Synthesis and in vitro evaluation of novel 8-aminoquinoline-pyrazolopyrimidine hybrids as potent antimalarial agents. Bioorganic & medicinal chemistry letters, 2015, Mar-01, Volume: 25, Issue:5 Topics: Aminoquinolines; Antimalarials; Humans; Malaria, Falciparum; Molecular Docking Simulation; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrazoles; Pyrimidines; Structure-Activity Relationship	2015
Benzoxaborole antimalarial agents. Part 4. Discovery of potent 6-(2-(alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles. Journal of medicinal chemistry, 2015, Jul-09, Volume: 58, Issue:13 Topics: Animals; Antimalarials; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Survival; Female; Humans; Jurkat Cells; Malaria, Falciparum; Mice; Microsomes, Liver; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrazines; Structure-Activity Relationship	2015
Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials. Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16 Topics: Animals; Antimalarials; High-Throughput Screening Assays; Humans; In Vitro Techniques; Malaria; Malaria, Falciparum; Mice; Mice, SCID; Microsomes, Liver; Plasmodium berghei; Plasmodium falciparum; Serine Proteinase Inhibitors; Structure-Activity Relationship; Triazoles	2015
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate. Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13 Topics: Amides; Animals; Antimalarials; Boron Compounds; Dogs; Female; Humans; Malaria; Malaria, Falciparum; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	2017
One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites. European journal of medicinal chemistry, 2018, Oct-05, Volume: 158 Topics: Acetylation; Antimalarials; Hep G2 Cells; Histone Deacetylase Inhibitors; Histones; Humans; Malaria, Falciparum; Peptoids; Plasmodium falciparum; Protozoan Proteins	2018
Discovery of fast-acting dual-stage antimalarial agents by profiling pyridylvinylquinoline chemical space via copper catalyzed azide-alkyne cycloadditions. European journal of medicinal chemistry, 2021, Jan-01, Volume: 209 Topics: Antimalarials; Azides; Copper; Cycloaddition Reaction; Hep G2 Cells; Humans; Life Cycle Stages; Malaria, Falciparum; Plasmodium falciparum; Quinolines	2021
Novel molecule combinations and corresponding hybrids targeting artemisinin-resistant Plasmodium falciparum parasites. Bioorganic & medicinal chemistry letters, 2021, 05-01, Volume: 39 Topics: Antimalarials; Artemisinins; Atovaquone; Dose-Response Relationship, Drug; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship; Triclosan	2021
Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials. Journal of medicinal chemistry, 2021, 09-09, Volume: 64, Issue:17 Topics: Administration, Oral; Animals; Antimalarials; Humans; Malaria, Falciparum; Mice; Molecular Structure; Plasmodium falciparum; Quinazolinones; Structure-Activity Relationship	2021
Ketoconazole increases atovaquone exposure following concomitant administration with Malarone® in healthy subjects. Journal of travel medicine, 2022, 07-14, Volume: 29, Issue:4 Topics: Antimalarials; Atovaquone; Drug Combinations; Healthy Volunteers; Humans; Ketoconazole; Malaria, Falciparum; Proguanil	2022
Using an antimalarial in mosquitoes overcomes Anopheles and Plasmodium resistance to malaria control strategies. PLoS pathogens, 2022, Volume: 18, Issue:6 Topics: Animals; Anopheles; Antimalarials; Atovaquone; Female; Malaria; Malaria, Falciparum; Plasmodium; Plasmodium falciparum	2022
Mitochondrially targeted proximity biotinylation and proteomic analysis in Plasmodium falciparum. PloS one, 2022, Volume: 17, Issue:8 Topics: Antimalarials; Atovaquone; Biotinylation; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Proteomics	2022
Transcriptional changes in Plasmodium falciparum upon conditional knock down of mitochondrial ribosomal proteins RSM22 and L23. PloS one, 2022, Volume: 17, Issue:10 Topics: Antimalarials; Atovaquone; DNA, Mitochondrial; Electron Transport Complex III; Humans; Malaria, Falciparum; Mitochondria; Mitochondrial Proteins; Plasmodium; Plasmodium falciparum; Ribosomal Proteins; RNA, Ribosomal; Transcription, Genetic	2022
Proguanil and atovaquone use is associated with lower colorectal cancer risk: a nationwide cohort study. BMC medicine, 2022, 11-10, Volume: 20, Issue:1 Topics: Adult; Antimalarials; Atovaquone; Cohort Studies; Colorectal Neoplasms; Drug Combinations; Humans; Malaria, Falciparum; Proguanil	2022
Creating and Validating Ligase Primers to Detect Single Nucleotide Polymorphisms Associated with Atovaquone Resistance in Plasmodium falciparum. The American journal of tropical medicine and hygiene, 2023, 04-05, Volume: 108, Issue:4 Topics: Antimalarials; Atovaquone; Cytochromes b; DNA Primers; Drug Combinations; Drug Resistance; Humans; Ligases; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Single Nucleotide; Proguanil	2023
In vitro activity of rhinacanthin analogues against drug resistant Plasmodium falciparum isolates from Northeast Thailand. Malaria journal, 2023, Mar-23, Volume: 22, Issue:1 Topics: Antimalarials; Atovaquone; Cytochromes b; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Thailand	2023
Atovaquone-proguanil for treating uncomplicated Plasmodium falciparum malaria. Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias, 2023, Volume: 35, Issue:2 Topics: Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria, Falciparum; Proguanil	2023
Amplicon Deep Sequencing Reveals Multiple Genetic Events Lead to Treatment Failure with Atovaquone-Proguanil in Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2023, 06-15, Volume: 67, Issue:6 Topics: Antimalarials; Atovaquone; Canada; Drug Combinations; High-Throughput Nucleotide Sequencing; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Recurrence; Sepharose; Tetrahydrofolate Dehydrogenase; Treatment Failure	2023
Microbiology spectrum, 2023, 06-15, Volume: 11, Issue:3 Topics: Animals; Atovaquone; DNA, Mitochondrial; Endodeoxyribonucleases; Humans; Malaria; Malaria, Falciparum; Parasites; Plasmodium falciparum; Protozoan Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2023
Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa. PloS one, 2023, Volume: 18, Issue:7 Topics: Africa, Western; Animals; Antimalarials; Atovaquone; Folic Acid Antagonists; Humans; Malaria, Falciparum; Plasmodium falciparum	2023
Clinically relevant atovaquone-resistant human malaria parasites fail to transmit by mosquito. Nature communications, 2023, 10-12, Volume: 14, Issue:1 Topics: Animals; Anopheles; Antimalarials; Antiparasitic Agents; Atovaquone; Humans; Malaria; Malaria, Falciparum; Mice; Parasites; Plasmodium falciparum; Vaccines	2023
Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery. Cell chemical biology, 2020, 02-20, Volume: 27, Issue:2 Topics: Antimalarials; Atovaquone; Drug Design; Electron Transport Chain Complex Proteins; Humans; Life Cycle Stages; Malaria, Falciparum; Metabolome; Metabolomics; Mitochondria; Plasmodium falciparum; Quinolines	2020
Two cases of airport-associated falciparum malaria in Frankfurt am Main, Germany, October 2019. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2019, Volume: 24, Issue:49 Topics: Adult; Airports; Antimalarials; Artesunate; Atovaquone; Fever; Genotype; Germany; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Polymerase Chain Reaction; Proguanil; Travel; Treatment Outcome	2019
Late clinical failure associated with cytochrome b codon 268 mutation during treatment of falciparum malaria with atovaquone-proguanil in traveller returning from Congo. Malaria journal, 2020, Jan-21, Volume: 19, Issue:1 Topics: Antimalarials; Artemisinins; Atovaquone; Codon; Congo; Cytochromes b; Drug Combinations; Drug Resistance; Female; France; Humans; Malaria, Falciparum; Middle Aged; Mutation; Phenanthrenes; Plasmodium falciparum; Proguanil; Quinolines; Tetrahydrofolate Dehydrogenase; Travel	2020
Lead Optimization of Dehydroemetine for Repositioned Use in Malaria. Antimicrobial agents and chemotherapy, 2020, 03-24, Volume: 64, Issue:4 Topics: Antimalarials; Atovaquone; Cell Line, Tumor; Drug Repositioning; Drug Resistance, Multiple; Drug Synergism; Emetine; Female; Hep G2 Cells; Humans; Malaria, Falciparum; Male; Membrane Potential, Mitochondrial; Plasmodium falciparum; Proguanil; Stereoisomerism	2020
A case of acute generalized exanthematous pustulosis caused by exposure to Atovaquone/proguanil. Journal of travel medicine, 2020, Sep-26, Volume: 27, Issue:6 Topics: Acute Generalized Exanthematous Pustulosis; Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Proguanil	2020
Targeted deep amplicon sequencing of kelch 13 and cytochrome b in Plasmodium falciparum isolates from an endemic African country using the Malaria Resistance Surveillance (MaRS) protocol. Parasites & vectors, 2020, Mar-14, Volume: 13, Issue:1 Topics: Africa; Anti-Infective Agents; Antimalarials; Artemisinins; Atovaquone; Cytochromes b; DNA, Protozoan; Drosophila Proteins; Drug Combinations; Drug Resistance; Genotype; High-Throughput Nucleotide Sequencing; Humans; Italy; Malaria, Falciparum; Microfilament Proteins; Plasmodium falciparum; Polymorphism, Single Nucleotide; Prevalence; Proguanil; Protozoan Proteins; Travel	2020
A Case report of atovaquone/proguanil induced esophageal ulcers. Journal of travel medicine, 2020, Nov-09, Volume: 27, Issue:7 Topics: Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria, Falciparum; Proguanil; Ulcer	2020
Selection of Cytochrome Antimicrobial agents and chemotherapy, 2021, 02-17, Volume: 65, Issue:3 Topics: Antimalarials; Atovaquone; Cambodia; Cytochromes b; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Proguanil	2021
Inhibition Mechanism of Antimalarial Drugs Targeting the Cytochrome bc Journal of chemical information and modeling, 2021, 03-22, Volume: 61, Issue:3 Topics: Antimalarials; Atovaquone; Cytochromes; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum	2021
Atovaquone/Proguanil Resistance in an Imported Malaria Case in Chile. The American journal of tropical medicine and hygiene, 2021, 03-29, Volume: 104, Issue:5 Topics: Adult; Antimalarials; Artesunate; Atovaquone; Chile; Cytochromes b; Drug Combinations; Drug Resistance; Female; Gene Expression; Humans; Malaria, Falciparum; Male; Mefloquine; Mutation; Nigeria; Parasitemia; Plasmodium falciparum; Proguanil; Protozoan Proteins; Recurrence; Tetrahydrofolate Dehydrogenase; Travel	2021
Menoctone Resistance in Malaria Parasites Is Conferred by M133I Mutations in Cytochrome Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:8 Topics: Animals; Anopheles; Antimalarials; Atovaquone; Cytochromes b; DNA, Protozoan; Drug Resistance; Female; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Mutation; Naphthoquinones; Plasmodium berghei; Plasmodium falciparum	2017
Acute malaria infection after atovaquone-proguanil prophylaxis. Journal of travel medicine, 2017, 03-01, Volume: 24, Issue:2 Topics: Antimalarials; Atovaquone; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Proguanil; Travel	2017
Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate:quinone oxidoreductase, a potential drug target. Biochimica et biophysica acta. Bioenergetics, 2018, Volume: 1859, Issue:3 Topics: Antimalarials; Atovaquone; Biocatalysis; Coumarins; Drug Synergism; Enzyme Inhibitors; Humans; Malaria, Falciparum; Malates; Mitochondrial Membranes; Oxaloacetic Acid; Oxidoreductases; Plasmodium falciparum; Protozoan Proteins	2018
Assessing drug efficacy against Plasmodium falciparum liver stages in vivo. JCI insight, 2018, 01-11, Volume: 3, Issue:1 Topics: Animals; Antimalarials; Atovaquone; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Liver; Malaria, Falciparum; Mice; Plasmodium falciparum; Proguanil; Pyrimidines; Triazoles	2018
Treatment for Uncomplicated Plasmodium falciparum Malaria in French Soldiers Deployed in Sub-Saharan Africa: Gaps Between Policy and Field Practice. Military medicine, 2018, 09-01, Volume: 183, Issue:9-10 Topics: Adult; Antimalarials; Artemisinins; Atovaquone; Central African Republic; Drug Combinations; Female; France; Health Knowledge, Attitudes, Practice; Humans; Malaria, Falciparum; Male; Middle Aged; Physicians; Proguanil; Retrospective Studies; Surveys and Questionnaires	2018
The Indian journal of medical research, 2017, Volume: 146, Issue:5 Topics: Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Atovaquone; Azithromycin; Chloroquine; Doxycycline; Ethanolamines; Fluorenes; Humans; India; Lumefantrine; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Quinine; Quinolines	2017
[Fluindione and falciparum malaria treated by atovaquone-proguanil]. Therapie, 2018, Volume: 73, Issue:5 Topics: Anticoagulants; Antimalarials; Atovaquone; Drug Combinations; Drug Interactions; Female; Heart Valve Prosthesis Implantation; Humans; Malaria, Falciparum; Middle Aged; Phenindione; Proguanil; Thrombosis; Travel	2018
A Case of Recrudescence Plasmodium falciparum Malaria Treated with Atovaquone-Proguanil. Turkiye parazitolojii dergisi, 2018, Volume: 42, Issue:3 Topics: Adult; Animals; Antimalarials; Atovaquone; Drug Combinations; Female; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Recurrence; Travel; Uganda	2018
Application of the automated haematology analyzer XN-30 for discovery and development of anti-malarial drugs. Malaria journal, 2019, Jan-14, Volume: 18, Issue:1 Topics: Antimalarials; Atovaquone; Automation, Laboratory; Chloroquine; Drug Discovery; Hematology; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Schizonts; Trophozoites	2019
Exposing Anopheles mosquitoes to antimalarials blocks Plasmodium parasite transmission. Nature, 2019, Volume: 567, Issue:7747 Topics: Africa; Animals; Anopheles; Antimalarials; Atovaquone; Cytochromes b; Female; Insecticide-Treated Bednets; Malaria, Falciparum; Models, Biological; Mosquito Control; Mosquito Vectors; Plasmodium falciparum; Time Factors	2019
Plasmodium falciparum Clearance Is Pitting-Dependent With Artemisinin-Based Drugs but Pitting-Independent With Atovaquone-Proguanil or Mefloquine. The Journal of infectious diseases, 2019, 07-02, Volume: 220, Issue:3 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Atovaquone; Child; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Proguanil; Young Adult	2019
Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families. PLoS genetics, 2013, Volume: 9, Issue:2 Topics: Antigenic Variation; Antigens; Atovaquone; Cytochromes b; Drug Resistance, Multiple; Evolution, Molecular; Genome, Protozoan; High-Throughput Nucleotide Sequencing; Host-Parasite Interactions; Humans; Malaria, Falciparum; Mitosis; Multidrug Resistance-Associated Proteins; Plasmodium falciparum	2013
Quinolone-3-diarylethers: a new class of antimalarial drug. Science translational medicine, 2013, Mar-20, Volume: 5, Issue:177 Topics: Animals; Antimalarials; Atovaquone; Drug Resistance; Drug Synergism; Life Cycle Stages; Malaria; Malaria, Falciparum; Mice; Plasmodium falciparum; Plasmodium vivax; Proguanil; Pyridones; Quinolones	2013
New options for the prevention and treatment of malaria: focus on the role of atovaquone and proguanil hydrochloride. Journal of travel medicine, 1999, Volume: 6 Suppl 1 Topics: Atovaquone; Chemoprevention; Dose-Response Relationship, Drug; Drug Combinations; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Travel	1999
[Treatment of severe and uncomplicated falciparum malaria in children in France]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2013, Volume: 20, Issue:11 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Atovaquone; Child; Drug Combinations; Ethanolamines; Fluorenes; France; Humans; Malaria, Falciparum; Proguanil; Quinolines	2013
Plasmodium falciparum malaria recrudescence occurring 2.5 years after leaving an endemic country. The Netherlands journal of medicine, 2013, Volume: 71, Issue:8 Topics: Antimalarials; Artemisinins; Atovaquone; Burkina Faso; Disease Progression; Drug Combinations; Endemic Diseases; Humans; Lactones; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Proguanil; Time Factors; Travel	2013
Autochthonous falciparum malaria possibly transmitted by luggage-carried vector in Paris, France, February 2013. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2013, Oct-03, Volume: 18, Issue:40 Topics: Animals; Atovaquone; Drug Combinations; Humans; Malaria, Falciparum; Male; Paris; Plasmodium falciparum; Proguanil; Travel; Treatment Outcome	2013
Atovaquone-proguanil in the treatment of imported uncomplicated Plasmodium falciparum malaria: a prospective observational study of 553 cases. Malaria journal, 2013, Nov-07, Volume: 12 Topics: Adolescent; Adult; Africa; Aged; Antimalarials; Asia; Atovaquone; Child; Drug Combinations; Female; France; Humans; Malaria, Falciparum; Male; Middle Aged; Proguanil; Transients and Migrants; Travel; Treatment Outcome; Young Adult	2013
Idiopathic acute myocarditis during treatment for controlled human malaria infection: a case report. Malaria journal, 2014, Jan-30, Volume: 13 Topics: Antimalarials; Atovaquone; Drug Combinations; Humans; Magnetic Resonance Imaging; Malaria, Falciparum; Male; Myocarditis; Plasmodium falciparum; Proguanil; Troponin T; Young Adult	2014
Imported malaria is stable from Africa but declining from Asia. Danish medical journal, 2014, Volume: 61, Issue:5 Topics: Adolescent; Adult; Africa; Aged; Antimalarials; Asia; Atovaquone; Chemoprevention; Child; Child, Preschool; Chloroquine; Delayed Diagnosis; Denmark; Drug Combinations; Female; Humans; Incidence; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Middle Aged; Primaquine; Proguanil; Recurrence; Risk Factors; Severity of Illness Index; Travel; Young Adult	2014
Emergence of resistance to atovaquone-proguanil in malaria parasites: insights from computational modeling and clinical case reports. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Adolescent; Antimalarials; Atovaquone; Child; DNA, Mitochondrial; Drug Combinations; Drug Resistance; Erythrocytes; Female; Genome, Mitochondrial; Humans; Infant; Life Cycle Stages; Malaria, Falciparum; Male; Middle Aged; Mitochondria; Models, Statistical; Mutation; Plasmodium falciparum; Proguanil; Treatment Failure; Young Adult	2014
"Collateral" effect of artemether in an atypical kidney involvement by Plasmodium falciparum malaria: a case report. Journal of vector borne diseases, 2014, Volume: 51, Issue:2 Topics: Administration, Intravenous; Administration, Oral; Adolescent; Artemether; Artemisinins; Atovaquone; Body Temperature; Cote d'Ivoire; Creatinine; Cyclophosphamide; Drug Combinations; Female; Glomerular Filtration Rate; Humans; Immunosuppression Therapy; Kidney; Malaria, Falciparum; Methylprednisolone; Proguanil; Proteinuria; Treatment Outcome	2014
The diminishing returns of atovaquone-proguanil for elimination of Plasmodium falciparum malaria: modelling mass drug administration and treatment. Malaria journal, 2014, Sep-24, Volume: 13 Topics: Antimalarials; Atovaquone; Drug Combinations; Drug Resistance; Humans; Insecticide-Treated Bednets; Malaria, Falciparum; Models, Biological; Plasmodium falciparum; Proguanil	2014
Understanding the mechanism of atovaquone drug resistance in Plasmodium falciparum cytochrome b mutation Y268S using computational methods. PloS one, 2014, Volume: 9, Issue:10 Topics: Antimalarials; Atovaquone; Computer Simulation; Cytochromes b; Drug Resistance; Malaria, Falciparum; Mutation; Plasmodium falciparum	2014
Artemether-lumefantrine compared to atovaquone-proguanil as a treatment for uncomplicated Plasmodium falciparum malaria in travelers. The American journal of tropical medicine and hygiene, 2015, Volume: 92, Issue:1 Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Atovaquone; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Male; Middle Aged; Proguanil; Travel	2015
An imported case of severe falciparum malaria with prolonged hemolytic anemia clinically mimicking a coinfection with babesiosis. The Korean journal of parasitology, 2014, Volume: 52, Issue:6 Topics: Anemia, Hemolytic; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Atovaquone; Azithromycin; Babesiosis; Benin; Blood; Coinfection; Drug Combinations; France; Humans; Korea; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Proguanil; Travel; Treatment Outcome	2014
Molecular characterization of the cytochrome b gene and in vitro atovaquone susceptibility of Plasmodium falciparum isolates from Kenya. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:3 Topics: Alleles; Antimalarials; Atovaquone; Codon; Cytochromes b; DNA, Protozoan; Drug Combinations; Kenya; Malaria, Falciparum; Microbial Sensitivity Tests; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Proguanil; Protozoan Proteins	2015
Microbial Metabolism of Atovaquone and Cytotoxicity of the Produced Phase I Metabolite. European journal of drug metabolism and pharmacokinetics, 2016, Volume: 41, Issue:5 Topics: Animals; Antimalarials; Atovaquone; Breast Neoplasms; Caenorhabditis elegans; Cell Line; Cell Line, Tumor; Female; Fibroblasts; Fungi; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Metabolic Detoxication, Phase I; Proguanil	2016
Plasmodium falciparum malaria occurring four years after leaving an endemic area. Acta clinica Belgica, 2016, Volume: 71, Issue:2 Topics: Antimalarials; Atovaquone; Disease Transmission, Infectious; Drug Combinations; Endemic Diseases; Female; Ghana; Humans; Malaria, Falciparum; Middle Aged; Plasmodium falciparum; Proguanil; Recurrence; Travel	2016
Cytogenetic and oxidative status of human lymphocytes after exposure to clinically relevant concentrations of antimalarial drugs atovaquone and proguanil hydrochloride in vitro. Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:6 Topics: Adult; Antimalarials; Atovaquone; Cell Survival; Cytogenetics; DNA Damage; Dose-Response Relationship, Drug; Drug Combinations; Glutathione; Humans; Lymphocytes; Malaria, Falciparum; Male; Malondialdehyde; Oxidative Stress; Plasmodium falciparum; Proguanil; Triazines	2015
39-Year-Old Woman With Headache and Fever. Mayo Clinic proceedings, 2015, Volume: 90, Issue:11 Topics: Adult; Antimalarials; Atovaquone; Carotid Artery Diseases; Carotid Artery, Internal; Chemoprevention; Cote d'Ivoire; Diagnosis, Differential; Drug Combinations; Female; Fever; Headache; Humans; Intracranial Aneurysm; Magnetic Resonance Imaging; Malaria, Falciparum; Neurosurgical Procedures; Plasmodium falciparum; Proguanil; Tomography, X-Ray Computed; Treatment Outcome	2015
Atovaquone-Proguanil Remains a Potential Stopgap Therapy for Multidrug-Resistant Plasmodium falciparum in Areas along the Thai-Cambodian Border. Antimicrobial agents and chemotherapy, 2015, Dec-28, Volume: 60, Issue:3 Topics: Antimalarials; Artemisinins; Atovaquone; Base Sequence; Cambodia; DNA, Protozoan; Drug Combinations; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Quinolines; Sequence Analysis, DNA; Thailand	2015
Artemisinin-based combination therapy (ACT) versus atovaquone-proguanil: do not choose between but, rather, combine them. Evidence-based medicine, 2016, Volume: 21, Issue:2 Topics: Amodiaquine; Antimalarials; Artemisinins; Atovaquone; Female; Humans; Malaria, Falciparum; Male; Proguanil	2016
Assessment of the Worldwide Antimalarial Resistance Network Standardized Procedure for In Vitro Malaria Drug Sensitivity Testing Using SYBR Green Assay for Field Samples with Various Initial Parasitemia Levels. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:4 Topics: Antimalarials; Artemisinins; Atovaquone; Benzothiazoles; Biological Assay; Chloroquine; Diamines; DNA, Protozoan; Drug Resistance; Erythrocytes; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Organic Chemicals; Parasitemia; Plasmodium falciparum; Public Health Surveillance; Quinolines; Reproducibility of Results; Sensitivity and Specificity	2016
In Vitro Analysis of the Interaction between Atovaquone and Proguanil against Liver Stage Malaria Parasites. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7 Topics: Antimalarials; Atovaquone; Drug Combinations; Hepatocytes; Humans; Inhibitory Concentration 50; Liver; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Triazines	2016
Advanced Molecular Detection of Malarone Resistance. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Adult; Antimalarials; Atovaquone; Cytochromes b; Drug Combinations; Drug Resistance; Gene Expression; High-Throughput Nucleotide Sequencing; Humans; Malaria, Falciparum; Male; Mutation; Nigeria; Plasmodium falciparum; Proguanil; Protozoan Proteins; Travel; Treatment Failure; United States	2016
Characterization of a Plasmodium falciparum Orthologue of the Yeast Ubiquinone-Binding Protein, Coq10p. PloS one, 2016, Volume: 11, Issue:3 Topics: Atovaquone; Carrier Proteins; Gene Expression Regulation; Humans; Malaria, Falciparum; Mitochondria; Plasmodium falciparum; Respiration; Saccharomyces cerevisiae; Ubiquinone	2016
Imported falciparum malaria in adults: host- and parasite-related factors associated with severity. The French prospective multicenter PALUREA cohort study. Intensive care medicine, 2016, Volume: 42, Issue:10 Topics: Adult; Analysis of Variance; Animals; Antigens, Protozoan; Antimalarials; Atovaquone; Biomarkers; C-Reactive Protein; Calcitonin; Drug Combinations; Female; France; Host-Parasite Interactions; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Proguanil; Prospective Studies; Protozoan Proteins; Quinine; Severity of Illness Index	2016
Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8 Topics: Animals; Antimalarials; Atovaquone; Drug Combinations; Drug Therapy, Combination; Electron Transport Complex III; Female; Malaria, Falciparum; Mice; Parasitemia; Plasmodium falciparum; Proguanil; Quinolones	2016
[Acquisition of atovaquone-proguanil resistance in imported falciparum malaria in a young child]. Presse medicale (Paris, France : 1983), 2017, Volume: 46, Issue:3 Topics: Antimalarials; Atovaquone; Child, Preschool; Communicable Diseases, Imported; Cote d'Ivoire; Drug Combinations; Drug Resistance, Multiple; Female; France; Humans; Malaria, Falciparum; Mali; Proguanil; Travel-Related Illness	2017
Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations. PloS one, 2017, Volume: 12, Issue:3 Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Computational Biology; Drug Combinations; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Emetine; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil	2017
The Malaria TaqMan Array Card Includes 87 Assays for Plasmodium falciparum Drug Resistance, Identification of Species, and Genotyping in a Single Reaction. Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:5 Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Resistance; Epidemiological Monitoring; Genotyping Techniques; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Pyrimethamine; Reagent Kits, Diagnostic; Sulfadoxine	2017
Bullous erythema multiforme after treatment with Malarone, a combination antimalarial composed of atovaquone and proguanil hydrochloride. Tropical doctor, 2008, Volume: 38, Issue:3 Topics: Antimalarials; Atovaquone; Drug Combinations; Erythema Multiforme; Female; Humans; Kenya; Malaria, Falciparum; Middle Aged; Proguanil	2008
In vitro and in vivo properties of ellagic acid in malaria treatment. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Chloroquine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ellagic Acid; Erythrocytes; Female; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Mice; Mice, Inbred Strains; Molecular Structure; Molecular Weight; Parasitemia; Parasitic Sensitivity Tests; Plasmodium; Plasmodium falciparum; Schizonts; Trophozoites	2009
Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-proguanil. Malaria journal, 2008, Nov-20, Volume: 7 Topics: Adult; Animals; Antimalarials; Atovaquone; Child, Preschool; Cytochromes b; DNA, Protozoan; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Humans; Malaria, Falciparum; Male; Middle Aged; Mutation; Parasitemia; Plasmodium falciparum; Polymerase Chain Reaction; Proguanil; Recurrence; Time Factors; Treatment Failure	2008
Novel pfdhps haplotypes among imported cases of Plasmodium falciparum malaria in the United Kingdom. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8 Topics: Adult; Alleles; Amino Acid Sequence; Animals; Antimalarials; Atovaquone; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Folic Acid Antagonists; Haplotypes; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Proguanil; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase; United Kingdom	2009
Atovaquone + proguanil: new indication. For children weighing as little as 5 kg; an inconvenient form. A flavoured syrup would be better suited to infants and young children. Prescrire international, 2009, Volume: 18, Issue:101 Topics: Administration, Oral; Antimalarials; Atovaquone; Body Weight; Chemistry, Pharmaceutical; Child; Child, Preschool; Dosage Forms; Drug Administration Schedule; Drug Approval; Drug Combinations; France; Humans; Infant; Malaria; Malaria, Falciparum; Proguanil; Tablets	2009
Mefloquine has more adverse effects than other drugs for malaria prophylaxis. BMJ (Clinical research ed.), 2009, Oct-13, Volume: 339 Topics: Antimalarials; Atovaquone; Doxycycline; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Proguanil; Review Literature as Topic; Suicide	2009
Effectiveness of malaria chemoprophylaxis against Plasmodium falciparum infection in UK travellers: retrospective observational data. Travel medicine and infectious disease, 2009, Volume: 7, Issue:6 Topics: Antimalarials; Atovaquone; Chemoprevention; Doxycycline; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Plasmodium falciparum; Proguanil; Retrospective Studies; Risk Factors; Travel; Treatment Outcome; United Kingdom	2009
Rapid identification of chloroquine and atovaquone drug resistance in Plasmodium falciparum using high-resolution melt polymerase chain reaction. Malaria journal, 2010, May-21, Volume: 9 Topics: Antimalarials; Atovaquone; Chloroquine; DNA, Protozoan; Drug Resistance; Haplotypes; Humans; Malaria, Falciparum; Membrane Transport Proteins; Nucleic Acid Denaturation; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Protozoan Proteins; Sensitivity and Specificity	2010
Letter to the editor of travel medicine and infectious disease. Travel medicine and infectious disease, 2010, Volume: 8, Issue:3 Topics: Antimalarials; Atovaquone; Chemoprevention; Doxycycline; Drug Combinations; Humans; Malaria, Falciparum; Mefloquine; Proguanil; Travel Medicine	2010
Different mutation patterns of Plasmodium falciparum among patients in Jimma University Hospital, Ethiopia. Malaria journal, 2010, Aug-07, Volume: 9 Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Atovaquone; Child; Cytochromes b; Drug Combinations; Drug Resistance; Ethanolamines; Ethiopia; Female; Fluorenes; Genotype; Hospitals, University; Humans; Malaria, Falciparum; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Prevalence; Proguanil; Quinine; Recurrence; Sequence Analysis, DNA; Tetrahydrofolate Dehydrogenase; Young Adult	2010
[Post-malaria neurological syndrome complicating a relapse of Plasmodium falciparum malaria after atovaquone-proguanil treatment]. Medecine et maladies infectieuses, 2011, Volume: 41, Issue:1 Topics: Antimalarials; Atovaquone; Cerebrospinal Fluid; Cognition Disorders; Confusion; Diagnosis, Differential; Drug Therapy, Combination; Encephalitis, Herpes Simplex; Hepatitis; Humans; Lymphocyte Count; Malaria, Cerebral; Malaria, Falciparum; Male; Meningitis, Aseptic; Middle Aged; Parasitemia; Proguanil; Recurrence; Syndrome	2011
Yeast dihydroorotate dehydrogenase as a new selectable marker for Plasmodium falciparum transfection. Molecular and biochemical parasitology, 2011, Volume: 177, Issue:1 Topics: Atovaquone; Dihydroorotate Dehydrogenase; Drug Resistance; Gene Silencing; Genetic Vectors; Humans; Malaria, Falciparum; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium falciparum; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transfection	2011
Parasitostatic effect of maslinic acid. I. Growth arrest of Plasmodium falciparum intraerythrocytic stages. Malaria journal, 2011, Apr-10, Volume: 10 Topics: Antimalarials; Atovaquone; Chloroquine; Erythrocytes; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Triterpenes	2011
[Atovaquone-proguanil treatment failure in Plasmodium falciparum]. Presse medicale (Paris, France : 1983), 2011, Volume: 40, Issue:11 Topics: Adult; Antimalarials; Atovaquone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Emigrants and Immigrants; France; Guinea; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Proguanil; Quinine; Recurrence; Travel; Treatment Failure	2011
Malaria therapy in HIV: drug interactions between nevirapine and quinine. International journal of STD & AIDS, 2011, Volume: 22, Issue:12 Topics: Anti-HIV Agents; Antimalarials; Atovaquone; Drug Combinations; Drug Interactions; HIV Infections; Humans; Malaria, Falciparum; Male; Middle Aged; Nevirapine; Nigeria; Proguanil; Quinine; Travel; United Kingdom	2011
Efficacy and safety of atovaquone-proguanil in treating imported malaria in Japan: the second report from the research group. Parasitology international, 2012, Volume: 61, Issue:3 Topics: Adult; Antimalarials; Atovaquone; Child, Preschool; Drug Combinations; Female; Humans; Infant; Japan; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Proguanil; Treatment Outcome	2012
Early treatment failure during treatment of Plasmodium falciparum malaria with atovaquone-proguanil in the Republic of Ivory Coast. Malaria journal, 2012, May-02, Volume: 11 Topics: Antimalarials; Atovaquone; Cote d'Ivoire; Cytochromes b; Drug Combinations; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Proguanil; Treatment Failure	2012
Erythema multiforme and Malarone(®). Travel medicine and infectious disease, 2012, Volume: 10, Issue:5-6 Topics: Aged; Antimalarials; Atovaquone; Diagnosis, Differential; Drug Combinations; Erythema Multiforme; Female; Humans; Malaria, Falciparum; Proguanil	2012
Focused Screening and Treatment (FSAT): a PCR-based strategy to detect malaria parasite carriers and contain drug resistant P. falciparum, Pailin, Cambodia. PloS one, 2012, Volume: 7, Issue:10 Topics: Artemisinins; Atovaquone; Base Sequence; Cambodia; Carrier State; Cross-Sectional Studies; Demography; Drug Combinations; Drug Resistance; Humans; Interviews as Topic; Malaria, Falciparum; Mass Screening; Molecular Sequence Data; Plasmodium falciparum; Polymerase Chain Reaction; Prevalence; Primaquine; Proguanil; Sequence Analysis, DNA; Statistics, Nonparametric	2012
Incidence of malaria among mosquito collectors conducting human landing catches in western Kenya. The American journal of tropical medicine and hygiene, 2013, Volume: 88, Issue:2 Topics: Adolescent; Adult; Atovaquone; Cohort Studies; Drug Combinations; Humans; Incidence; Kenya; Logistic Models; Malaria, Falciparum; Male; Middle Aged; Proguanil; Prospective Studies; Risk Factors; Surveys and Questionnaires; Young Adult	2013
[Experience with the combination atovaquone-proguanil in the treatment of uncomplicated Plasmodium falciparum malaria--report of 112 cases]. Medecine tropicale : revue du Corps de sante colonial, 2002, Volume: 62, Issue:3 Topics: Adolescent; Adult; Aged; Antimalarials; Atovaquone; Drug Therapy, Combination; Female; Gastritis; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Proguanil; Recurrence; Retrospective Studies; Treatment Outcome	2002
Persistence of atovaquone in human sera following treatment: inhibition of Plasmodium falciparum development in vivo and in vitro. The American journal of tropical medicine and hygiene, 2003, Volume: 68, Issue:1 Topics: Animals; Anopheles; Antimalarials; Atovaquone; Female; Humans; Insect Vectors; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Proguanil; Serum Bactericidal Test	2003
Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports. BMJ (Clinical research ed.), 2003, Mar-22, Volume: 326, Issue:7390 Topics: Antimalarials; Antiprotozoal Agents; Atovaquone; Child, Preschool; Chromatography, High Pressure Liquid; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Naphthoquinones; Proguanil; Tablets	2003
Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker. Malaria journal, 2003, Mar-19, Volume: 2 Topics: Animals; Antimalarials; Antiprotozoal Agents; Atovaquone; Codon; Drug Resistance; Electron Transport Complex III; Genetic Markers; Humans; Malaria, Falciparum; Mutation; Naphthoquinones; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proguanil; Triazines	2003
Problems in prescribing malaria chemoprophylaxis for travelers. Fundamental & clinical pharmacology, 2003, Volume: 17, Issue:2 Topics: Animals; Antimalarials; Atovaquone; Child; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple; Endemic Diseases; Female; Humans; Immunocompromised Host; Insect Bites and Stings; Malaria, Falciparum; Mosquito Control; Naphthoquinones; Patient Compliance; Pregnancy; Proguanil; Travel	2003
Plasmodium falciparum outwits Malarone, protector of travellers. Bulletin of the World Health Organization, 2003, Volume: 81, Issue:5 Topics: Animals; Antimalarials; Atovaquone; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Male; Naphthoquinones; Plasmodium falciparum; Proguanil	2003
Genetic confirmation of atovaquone-proguanil-resistant Plasmodium falciparum malaria acquired by a nonimmune traveler to East Africa. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Aug-01, Volume: 37, Issue:3 Topics: Adult; Animals; Antimalarials; Atovaquone; Cytochrome b Group; Drug Resistance; Drug Therapy, Combination; Female; Humans; Kenya; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Proguanil; Travel; Treatment Failure	2003
Molecular epidemiology of malaria in Cameroon. XVII. Baseline monitoring of atovaquone-resistant Plasmodium falciparum by in vitro drug assays and cytochrome b gene sequence analysis. The American journal of tropical medicine and hygiene, 2003, Volume: 69, Issue:2 Topics: Adolescent; Adult; Animals; Antimalarials; Atovaquone; Cameroon; Child; Culture Media; DNA Primers; Drug Resistance; Electron Transport Complex III; Humans; Malaria, Falciparum; Naphthoquinones; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymerase Chain Reaction	2003
Atovaquone-proguanil for recrudescent Plasmodium falciparum in Vietnam. Annals of tropical medicine and parasitology, 2003, Volume: 97, Issue:6 Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Child; Disease Outbreaks; Drug Combinations; Drug Resistance, Multiple; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Naphthoquinones; Parasitemia; Plasmodium falciparum; Proguanil; Recurrence; Sesquiterpenes; Treatment Failure; Vietnam	2003
Diagnosis and treatment of malaria in children. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Nov-15, Volume: 37, Issue:10 Topics: Animals; Antimalarials; Atovaquone; Child; Chloroquine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Proguanil; Pyrimethamine; Sulfadoxine	2003
Atovaquone/proguanil resistance in Africa: a case report. Scandinavian journal of infectious diseases, 2003, Volume: 35, Issue:11-12 Topics: Adult; Africa; Animals; Atovaquone; Bacterial Proteins; Cytochrome b Group; Denmark; Drug Resistance, Multiple; Drug Therapy, Combination; Ferritins; Humans; Malaria, Falciparum; Male; Microbial Sensitivity Tests; Mutation; Naphthoquinones; Pharmacogenetics; Plasmodium falciparum; Polymerase Chain Reaction; Proguanil; Risk Assessment; Travel; Treatment Failure	2003
Short communication: Prevalence of mutations associated with resistance to atovaquone and to the antifolate effect of proguanil in Plasmodium falciparum isolates from northern Ghana. Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:3 Topics: Animals; Antimalarials; Atovaquone; Child, Preschool; Cytochromes b; Drug Combinations; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Folic Acid Antagonists; Ghana; Humans; Infant; Malaria, Falciparum; Male; Mutation; Naphthoquinones; Plasmodium falciparum; Polymorphism, Restriction Fragment Length; Proguanil; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Triazines	2004
Malarone treatment failure not associated with previously described mutations in the cytochrome b gene. Malaria journal, 2004, Jun-08, Volume: 3 Topics: Adult; Animals; Antimalarials; Atovaquone; Biological Availability; Cytochromes b; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Point Mutation; Proguanil; Treatment Failure	2004
Quinine-resistant severe falciparum malaria effectively treated with atovaquone and proguanil hydrochloride combination therapy. Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:7 Topics: Adult; Atovaquone; Blood Chemical Analysis; Bone Marrow Cells; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Naphthoquinones; Proguanil; Severity of Illness Index; Tomography, X-Ray Computed; Treatment Outcome	2004
Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe. The Journal of infectious diseases, 2004, Nov-01, Volume: 190, Issue:9 Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Animals; Antimalarials; Atovaquone; Codon; Cytochromes b; DNA, Protozoan; Drug Combinations; Drug Resistance; Europe; Female; Genes, Protozoan; Humans; Malaria, Falciparum; Male; Middle Aged; Molecular Epidemiology; Mutation, Missense; Naphthoquinones; Plasmodium falciparum; Point Mutation; Polymorphism, Restriction Fragment Length; Proguanil; Protozoan Proteins; Treatment Failure	2004
In vitro recrudescence of Plasmodium falciparum parasites suppressed to dormant state by atovaquone alone and in combination with proguanil. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2005, Volume: 99, Issue:1 Topics: Animals; Antimalarials; Atovaquone; Culture Media; Cytochrome b Group; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Naphthoquinones; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Recurrence; Triazines	2005
Emergence of atovaquone-proguanil resistance during treatment of Plasmodium falciparum malaria acquired by a non-immune north American traveller to west Africa. The American journal of tropical medicine and hygiene, 2005, Volume: 72, Issue:4 Topics: Adult; Animals; Antimalarials; Atovaquone; Canada; Cytochromes b; Drug Resistance; Female; Humans; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Proguanil; Sierra Leone	2005
Lengthy antimalarial activity of atovaquone in human plasma following atovaquone-proguanil administration. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:10 Topics: Animals; Antimalarials; Atovaquone; Biological Assay; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Half-Life; Humans; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Proguanil	2005
Apparent absence of atovaquone/proguanil resistance in 477 Plasmodium falciparum isolates from untreated French travellers. The Journal of antimicrobial chemotherapy, 2006, Volume: 57, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Atovaquone; Child; Child, Preschool; Cytochromes b; Drug Resistance; Drug Synergism; Female; France; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Restriction Fragment Length; Proguanil; Travel	2006
Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria. European journal of clinical pharmacology, 2006, Volume: 62, Issue:5 Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Antimalarials; Artemisinins; Artesunate; Atovaquone; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Half-Life; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Proguanil; Sesquiterpenes; Thailand	2006
Detection of atovaquone-proguanil resistance conferring mutations in Plasmodium falciparum cytochrome b gene in Luanda, Angola. Malaria journal, 2006, Apr-05, Volume: 5 Topics: Angola; Animals; Antimalarials; Atovaquone; Cytochromes b; DNA Mutational Analysis; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Naphthoquinones; Plasmodium falciparum; Polymorphism, Genetic; Proguanil; Travel	2006
[Malaria: a medical and economic problem]. Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:4 Pt 1 Topics: Anti-Infective Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Health Care Costs; Humans; Lumefantrine; Malaria, Falciparum; Naphthoquinones; Proguanil; Sesquiterpenes; Survival Rate; World Health Organization	2006
Prevalence of Plasmodium falciparum cytochrome b gene mutations in isolates imported from Africa, and implications for atovaquone resistance. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006, Volume: 100, Issue:10 Topics: Africa; Amino Acid Sequence; Animals; Antimalarials; Atovaquone; Cytochromes b; Drug Resistance; Emigration and Immigration; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymerase Chain Reaction	2006
Drug-induced death of the asexual blood stages of Plasmodium falciparum occurs without typical signs of apoptosis. Microbes and infection, 2006, Volume: 8, Issue:6 Topics: Animals; Antimalarials; Apoptosis; Atovaquone; Cells, Cultured; Chloroquine; DNA Fragmentation; DNA, Protozoan; Enzyme Inhibitors; Erythrocytes; Etoposide; Flow Cytometry; Humans; In Situ Nick-End Labeling; Malaria, Falciparum; Membrane Potentials; Mitochondrial Membranes; Naphthoquinones; Nitric Oxide Donors; Parasitemia; Penicillamine; Plasmodium falciparum	2006
Clinical atovaquone-proguanil resistance of Plasmodium falciparum associated with cytochrome b codon 268 mutations. Microbes and infection, 2006, Volume: 8, Issue:11 Topics: Adolescent; Adult; Amino Acid Substitution; Animals; Antimalarials; Atovaquone; Codon; Cytochromes b; Drug Resistance; Female; Genotype; Humans; Malaria, Falciparum; Male; Middle Aged; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil	2006
Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa. Malaria journal, 2006, Oct-04, Volume: 5 Topics: Adult; Amino Acid Sequence; Amino Acid Substitution; Animals; Antimalarials; Atovaquone; Child; Codon; Cytochromes b; DNA, Protozoan; Drug Resistance; Humans; Malaria, Falciparum; Malawi; Molecular Sequence Data; Mutation, Missense; Naphthoquinones; Nigeria; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proguanil; Protozoan Proteins; Senegal; Sequence Alignment; Sequence Homology, Amino Acid; Travel	2006
Efficacy and safety of atovaquone-proguanil compared with mefloquine in the treatment of nonimmune patients with uncomplicated P. falciparum malaria in Japan. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2006, Volume: 12, Issue:5 Topics: Adult; Antimalarials; Atovaquone; Child, Preschool; Female; Humans; Immunocompetence; Infant; Japan; Malaria, Falciparum; Male; Mefloquine; Proguanil	2006
Atovaquone-proguanil: report from the CDC expert meeting on malaria chemoprophylaxis (II). The American journal of tropical medicine and hygiene, 2007, Volume: 76, Issue:2 Topics: Adult; Animals; Antimalarials; Atovaquone; Child; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Pregnancy; Proguanil; Randomized Controlled Trials as Topic; Travel	2007
Analyses of cytochrome b mutations in Plasmodium falciparum isolates in Thai-Myanmar border. Travel medicine and infectious disease, 2007, Volume: 5, Issue:2 Topics: Animals; Antimalarials; Atovaquone; Cytochromes b; DNA Primers; DNA, Protozoan; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Proguanil; Thailand; Travel	2007
First case of emergence of atovaquone resistance in Plasmodium falciparum during second-line atovaquone-proguanil treatment in South America. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6 Topics: Animals; Antimalarials; Atovaquone; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; South America	2007
Parallel evolution of adaptive mutations in Plasmodium falciparum mitochondrial DNA during atovaquone-proguanil treatment. Molecular biology and evolution, 2007, Volume: 24, Issue:8 Topics: Animals; Antimalarials; Atovaquone; Base Sequence; Biological Evolution; Cytochromes b; DNA Mutational Analysis; DNA, Mitochondrial; Drug Resistance; Humans; Malaria, Falciparum; Molecular Sequence Data; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Proguanil; Sequence Homology, Nucleic Acid	2007
Selective ambulatory management of Plasmodium falciparum malaria in paediatric refugees. Archives of disease in childhood, 2007, Volume: 92, Issue:11 Topics: Adolescent; Ambulatory Care; Antimalarials; Atovaquone; Australia; Child; Child, Preschool; Female; Follow-Up Studies; Hospitalization; Humans; Malaria, Falciparum; Male; Mefloquine; Parasitemia; Patient Compliance; Proguanil; Quinine; Refugees	2007
A man with tropical travel history, fever, and pulmonary infiltrates. Comprehensive therapy, 2007,Spring, Volume: 33, Issue:1 Topics: Africa, Western; Aged; Animals; Antimalarials; Atovaquone; Doxycycline; Drug Combinations; Fever; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Proguanil; Quinidine; Quinine; Respiratory Distress Syndrome; Travel; Tropical Climate	2007
Synergistic interaction between atovaquone and retinol in Plasmodium falciparum in vitro. Wiener klinische Wochenschrift, 2007, Volume: 119, Issue:19-20 Supp Topics: Animals; Antimalarials; Atovaquone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Lethal Dose 50; Malaria, Falciparum; Plasmodium falciparum; Survival Rate; Treatment Outcome; Vitamin A	2007
Synergistic interaction between monodesbutyl-benflumetol and retinol in Plasmodium falciparum. Wiener klinische Wochenschrift, 2007, Volume: 119, Issue:19-20 Supp Topics: Animals; Antimalarials; Atovaquone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lethal Dose 50; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Survival Rate; Treatment Outcome; Vitamin A	2007
In vitro atovaquone/proguanil susceptibility and characterization of the cytochrome b gene of Plasmodium falciparum from different endemic regions of Thailand. Malaria journal, 2008, Jan-28, Volume: 7 Topics: Animals; Antimalarials; Atovaquone; Codon; Cytochromes b; Drug Resistance, Multiple; Genes, Protozoan; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Point Mutation; Polymorphism, Restriction Fragment Length; Proguanil; Protozoan Proteins; Thailand	2008
Plasmodium falciparum malaria and atovaquone-proguanil treatment failure. Emerging infectious diseases, 2008, Volume: 14, Issue:2 Topics: Adult; Animals; Antimalarials; Atovaquone; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Proguanil; Treatment Failure	2008
[Tolerance and efficacy of atovaquone-proguanil for the treatment of paediatric imported Plasmodium falciparum malaria in France: clinical practice in a university hospital in Paris]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2008, Volume: 15, Issue:3 Topics: Animals; Antimalarials; Atovaquone; C-Reactive Protein; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; Drug Tolerance; Hospitals, University; Humans; Liver Function Tests; Malaria, Falciparum; Paris; Plasmodium falciparum; Proguanil; Retrospective Studies; Travel	2008
Atovaquone-proguanil resistance in imported falciparum malaria in a young child. The Pediatric infectious disease journal, 2008, Volume: 27, Issue:6 Topics: Animals; Antimalarials; Atovaquone; Child; Cytochromes c; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Male; Mozambique; Mutation, Missense; North America; Parasitemia; Plasmodium falciparum; Proguanil; Treatment Failure	2008
PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists. The American journal of tropical medicine and hygiene, 1993, Volume: 49, Issue:1 Topics: Administration, Oral; Animals; Antimalarials; Aotus trivirgatus; Atovaquone; Drug Synergism; Folic Acid Antagonists; Imides; Injections, Subcutaneous; Malaria, Falciparum; Mice; Naphthoquinones; Phenyl Ethers; Plasmodium falciparum; Proguanil; Sulfamethoxazole; Triazines	1993
Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand. The American journal of tropical medicine and hygiene, 1996, Volume: 54, Issue:1 Topics: Acute Disease; Adolescent; Adult; Aged; Antimalarials; Atovaquone; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones	1996
Direct comparison of antimalarial activity among PS-15 combination therapies by bioassay of serum samples from treated Saimiri sciureus. The Journal of parasitology, 1997, Volume: 83, Issue:3 Topics: Animals; Antimalarials; Atovaquone; Biological Assay; Dapsone; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil; Regression Analysis; Saimiri; Sulfamethoxazole	1997
Antimalaria activity of the triple combination of proguanil, atovaquone and dapsone. Acta tropica, 1997, Sep-30, Volume: 67, Issue:3 Topics: Animals; Antimalarials; Atovaquone; Dapsone; Drug Resistance, Multiple; Drug Synergism; Drug Therapy, Combination; Humans; Malaria, Falciparum; Naphthoquinones; Plasmodium falciparum; Proguanil; Thailand	1997
Malarone-donation programme in Africa. Lancet (London, England), 1998, Feb-28, Volume: 351, Issue:9103 Topics: Africa; Altruism; Antimalarials; Atovaquone; Developing Countries; Drug Combinations; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil	1998
Malaria prophylaxis for the 1990s and beyond. British journal of hospital medicine, 1997, Dec-10, Volume: 58, Issue:11 Topics: Antimalarials; Atovaquone; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Mefloquine; Naphthoquinones; Proguanil	1997
Antimalarial drug resistance and combination chemotherapy. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1999, Apr-29, Volume: 354, Issue:1384 Topics: Animals; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Sesquiterpenes	1999
Atovaquone-proguanil for falciparum malaria in the Philippines. The Journal of infectious diseases, 2000, Volume: 181, Issue:1 Topics: Antimalarials; Atovaquone; Chloroquine; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Philippines; Proguanil; Pyrimethamine; Sulfadoxine	2000
Atovaquone/Proguanil (Malarone) for malaria. The Medical letter on drugs and therapeutics, 2000, Nov-27, Volume: 42, Issue:1093 Topics: Abdominal Pain; Administration, Oral; Antimalarials; Atovaquone; Clinical Trials as Topic; Drug Combinations; Drug Interactions; Fees, Pharmaceutical; Humans; Malaria, Falciparum; Naphthoquinones; Nausea; Proguanil	2000
Prophylactic effect of Malarone against malaria: all good news? Lancet (London, England), 2000, Dec-02, Volume: 356, Issue:9245 Topics: Antimalarials; Atovaquone; Chloroquine; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil; Travel; Treatment Outcome	2000
A political analysis of corporate drug donations: the example of Malarone in Kenya. Health policy and planning, 2001, Volume: 16, Issue:2 Topics: Antimalarials; Atovaquone; Communicable Disease Control; Drug Combinations; Drug Industry; Financing, Organized; Humans; Interinstitutional Relations; Kenya; Malaria, Falciparum; Naphthoquinones; Policy Making; Politics; Private Sector; Program Evaluation; Proguanil; Public Sector	2001
Malaria remains a military medical problem. Journal of the Royal Army Medical Corps, 2001, Volume: 147, Issue:3 Topics: Adult; Animals; Antimalarials; Atovaquone; Chloroquine; Drug Combinations; Global Health; Humans; Kenya; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Military Medicine; Military Personnel; Naphthoquinones; Patient Compliance; Plasmodium falciparum; Plasmodium vivax; Proguanil; Sierra Leone; Treatment Failure; Treatment Outcome; United Kingdom	2001
Time of treatment influences the appearance of drug-resistant parasites in Plasmodium falciparum infections. Parasitology, 2001, Volume: 123, Issue:Pt 6 Topics: Animals; Antibodies, Protozoan; Antimalarials; Atovaquone; Computer Simulation; Drug Resistance; Humans; Malaria, Falciparum; Models, Biological; Mutation; Naphthoquinones; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Time Factors	2001
[Malarone: a new antimalarial for malaria chemoprevention]. Medecine tropicale : revue du Corps de sante colonial, 2002, Volume: 62, Issue:1 Topics: Antimalarials; Atovaquone; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Proguanil	2002
Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria. Malaria journal, 2002, Feb-08, Volume: 1 Topics: Amino Acid Substitution; Animals; Antimalarials; Atovaquone; Codon; Cytochromes b; Drug Combinations; Drug Resistance; Humans; London; Malaria, Falciparum; Male; Middle Aged; Mutation, Missense; Naphthoquinones; Nigeria; Parasitemia; Plasmodium falciparum; Proguanil; Protozoan Proteins; Travel	2002
566C80: a potent broad spectrum anti-infective agent with activity against malaria and opportunistic infections in AIDS patients. Drugs under experimental and clinical research, 1991, Volume: 17, Issue:9 Topics: 4-Quinolones; Acquired Immunodeficiency Syndrome; Adult; Animals; Anti-Infective Agents; Antimalarials; Aotus trivirgatus; Atovaquone; Dogs; Humans; Malaria, Falciparum; Male; Microsomes, Liver; Middle Aged; NADP; Naphthoquinones; Opportunistic Infections; Plasmodium; Rats; Toxoplasma	1991