Page last updated: 2024-08-25

atovaquone and Central Nervous System Toxoplasmosis

atovaquone has been researched along with Central Nervous System Toxoplasmosis in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	15 (60.00)	18.2507
2000's	3 (12.00)	29.6817
2010's	5 (20.00)	24.3611
2020's	2 (8.00)	2.80

Authors

Authors	Studies
Bajohr, LL; Bohne, W; Gross, U; Liesenfeld, O; Ma, L; Platte, C; Tietze, LF	1
Dalimi, A; Ghaffarifar, F; Pirestani, M; Zouei, N	1
Chorlton, SD	1
Hikosaka, K; Miyata, N; Norose, K; Tachikawa, N; Yoshimura, Y	1
Bejjanki, H; Koratala, A; Olaoye, OA; Santos, AH	1
Alfaro, RM; Calderón, MM; Kovacs, JA; Kumar, P; McManus, M; Pau, AK; Penzak, SR	1
Borner, K; Bushrab, FN; Dathe, M; Dunay, IR; Fitzner, R; Lachenmaier, S; Liesenfeld, O; Mauludin, R; Müller, RH; Shubar, HM	1
Borner, K; Fitzner, R; Heimesaat, MM; Lachenmaier, S; Liesenfeld, O; Lohman, U; Mauludin, R; Mueller, RH; Shubar, HM	1
Arasteh, K; Borner, K; Bushrab, FN; Dunay, IR; Fitzner, R; Heimesaat, MM; Kurowski, M; Liesenfeld, O; Müller, RH; Stocker, H	1
Fisher, S; Levy, I; Megged, O; Shalit, I; Stein, J; Yaniv, I	1
Bagneres, D; Cretel, E; Durand, JM; Guillemot, E; Kaplanski, G; Soubeyrand, J	1
Winstanley, P	1
Bouboulis, DA; Frieri, M; Madden, J; Rubinstein, A; Shliozberg, J	1
Cardenal, C; Gatell, JM; Guelar, A; Mallolas, J; Miró, JM; Soriano, E; Zamora, L	1
Araujo, FG; Ferguson, DJ; Huskinson-Mark, J; Remington, JS	1
Araujo, FG; Remington, JS; Slifer, T	1
Chouette, I; Lafeuillade, A; Navarreté, MS; Pellegrino, P; Poggi, C; Profizi, N; Quilichini, R	1
Flaherty, JF; Haile, LG	1
Fish, DN; Goodwin, SD	1
Araujo, FG; Remington, JS; Suzuki, Y	1
Gourdon, D; Katlama, C; Lapierre, D; Mouthon, B; Rousseau, F	1
Brettle, RP; Burns, SM; Flegg, PJ; Laing, RB; Leen, CL	1
Kovacs, J; Leoung, G; Rogers, M; Scott, J; Stansell, J; Torres, RA; Weinberg, W	1
Gormley, PD; Lightman, S; Minnasian, D; Pavesio, CE	1
Kovacs, JA	1

Reviews

1 review(s) available for atovaquone and Central Nervous System Toxoplasmosis

Article	Year
Atovaquone: a review. The Annals of pharmacotherapy, 1993, Volume: 27, Issue:12 Topics: AIDS-Related Opportunistic Infections; Animals; Antifungal Agents; Antiprotozoal Agents; Atovaquone; Clinical Trials as Topic; Humans; Male; Naphthoquinones; Pneumonia, Pneumocystis; Toxoplasmosis, Cerebral	1993

Trials

4 trial(s) available for atovaquone and Central Nervous System Toxoplasmosis

Article	Year
Efavirenz but Not Atazanavir/Ritonavir Significantly Reduces Atovaquone Concentrations in HIV-Infected Subjects. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016, Apr-15, Volume: 62, Issue:8 Topics: Administration, Oral; Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Anti-Infective Agents; Atazanavir Sulfate; Atovaquone; Benzoxazines; Cyclopropanes; Drug Interactions; Drug Therapy, Combination; Encephalitis; Female; HIV Infections; HIV Protease Inhibitors; Humans; Male; Middle Aged; Pneumonia, Pneumocystis; Reverse Transcriptase Inhibitors; Ritonavir; Toxoplasmosis, Cerebral; Young Adult	2016
Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group. AIDS (London, England), 1996, Volume: 10, Issue:10 Topics: Acquired Immunodeficiency Syndrome; Adult; Antiprotozoal Agents; Atovaquone; Clindamycin; Encephalitis; Female; Humans; Male; Naphthoquinones; Pyrimethamine; Recurrence; Risk Factors; Sulfadiazine; Survival Analysis; Time Factors; Toxoplasmosis, Cerebral	1996
Atovaquone for salvage treatment and suppression of toxoplasmic encephalitis in patients with AIDS. Atovaquone/Toxoplasmic Encephalitis Study Group. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:3 Topics: Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Atovaquone; Brain; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Naphthoquinones; Salvage Therapy; Tomography, X-Ray Computed; Toxoplasmosis, Cerebral	1997
Efficacy of atovaquone in treatment of toxoplasmosis in patients with AIDS. The NIAID-Clinical Center Intramural AIDS Program. Lancet (London, England), 1992, Sep-12, Volume: 340, Issue:8820 Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Anti-Infective Agents; Atovaquone; Biopsy; Enzyme-Linked Immunosorbent Assay; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Naphthoquinones; Recurrence; Toxoplasmosis, Cerebral	1992

Other Studies

20 other study(ies) available for atovaquone and Central Nervous System Toxoplasmosis

Article	Year
In vitro and in vivo activities of 1-hydroxy-2-alkyl-4(1H)quinolone derivatives against Toxoplasma gondii. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Animals; Antiparasitic Agents; Cells, Cultured; DNA, Protozoan; Female; Fibroblasts; Flow Cytometry; Humans; Liver; Lung; Mice; Peritoneal Cavity; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Toxoplasma; Toxoplasmosis, Animal; Toxoplasmosis, Cerebral	2010
Assessment of tissue levels of miR-146a and proinflammatory cytokines in experimental cerebral toxoplasmosis following atovaquone and clindamycin treatment: An in vivo study. Microbial pathogenesis, 2023, Volume: 184 Topics: Animals; Anti-Bacterial Agents; Atovaquone; Clindamycin; Cysts; Cytokines; Interleukin-10; Interleukin-6; Mice; MicroRNAs; Toxoplasma; Toxoplasmosis, Cerebral	2023
Adjunctive bradyzoite-directed therapy for reducing complications of congenital toxoplasmosis. Medical hypotheses, 2019, Volume: 133 Topics: Animals; Antiprotozoal Agents; Atovaquone; Brain; Chorioretinitis; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Therapy, Combination; Eye; Humans; Infant; Infant, Newborn; Mice; Models, Biological; Recurrence; Spiramycin; Toxoplasma; Toxoplasmosis, Animal; Toxoplasmosis, Cerebral; Toxoplasmosis, Congenital; Toxoplasmosis, Ocular	2019
Desensitization to trimethoprim-sulfamethoxazole in a toxoplasmic encephalitis patient who was intolerant to conventional treatments. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2020, Volume: 26, Issue:3 Topics: Adult; AIDS-Related Opportunistic Infections; Atovaquone; Brain; Clindamycin; Coccidiostats; Desensitization, Immunologic; Humans; Male; Toxoplasmosis, Cerebral; Trimethoprim, Sulfamethoxazole Drug Combination	2020
Liver transplant, toxoplasmosis and kidney stones: connecting the dots. BMJ case reports, 2019, Feb-15, Volume: 12, Issue:2 Topics: Aftercare; Antimalarials; Antiprotozoal Agents; Atovaquone; Brain; Brain Edema; Female; Humans; Kidney Calculi; Liver Transplantation; Magnetic Resonance Imaging; Middle Aged; Pentamidine; Pneumonia, Pneumocystis; Sulfadiazine; Toxoplasmosis, Cerebral; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Ultrasonography	2019
The role of apolipoprotein E in uptake of atovaquone into the brain in murine acute and reactivated toxoplasmosis. Journal of drug targeting, 2009, Volume: 17, Issue:4 Topics: Animals; Antiprotozoal Agents; Apolipoproteins E; Atovaquone; Biological Transport; Blood-Brain Barrier; Brain; Coculture Techniques; Mice; Poloxamer; Polysorbates; Rats; Rats, Wistar; Surface-Active Agents; Tissue Distribution; Toxoplasmosis, Animal; Toxoplasmosis, Cerebral	2009
SDS-coated atovaquone nanosuspensions show improved therapeutic efficacy against experimental acquired and reactivated toxoplasmosis by improving passage of gastrointestinal and blood-brain barriers. Journal of drug targeting, 2011, Volume: 19, Issue:2 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Atovaquone; Biological Availability; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Excipients; Mice; Nanoparticles; Poloxamer; Sodium Dodecyl Sulfate; Suspensions; Tissue Distribution; Toxoplasma; Toxoplasmosis, Animal; Toxoplasmosis, Cerebral	2011
Atovaquone maintenance therapy prevents reactivation of toxoplasmic encephalitis in a murine model of reactivated toxoplasmosis. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:12 Topics: Animals; Antiprotozoal Agents; Atovaquone; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Female; Injections, Intravenous; Liver; Lung; Mass Spectrometry; Meninges; Mice; Mice, Inbred C57BL; Naphthoquinones; Pyrimethamine; Sulfadiazine; Survival Analysis; Toxoplasmosis, Cerebral	2004
Breakthrough cerebral toxoplasmosis in a patient receiving atovaquone prophylaxis after a hematopoietic stem cell transplantation. Pediatric transplantation, 2008, Volume: 12, Issue:8 Topics: Anti-Infective Agents; Atovaquone; Child; Encephalitis; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Time Factors; Toxoplasmosis, Cerebral; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination	2008
Failure of atovaquone in the treatment of cerebral toxoplasmosis. AIDS (London, England), 1995, Volume: 9, Issue:7 Topics: Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Atovaquone; Female; Humans; Naphthoquinones; Toxoplasmosis, Cerebral; Treatment Failure	1995
Drug treatment of toxoplasmic encephalitis in acquired immunodeficiency syndrome. Postgraduate medical journal, 1995, Volume: 71, Issue:837 Topics: AIDS-Related Opportunistic Infections; Atovaquone; Clindamycin; Coccidiostats; Humans; Naphthoquinones; Pyrimethamine; Sulfadiazine; Toxoplasmosis, Cerebral	1995
Cerebral toxoplasmosis in childhood and adult HIV infection treated with 1-4 hydroxynaphthoquinone and rapid desensitization with pyrimethamine. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1995, Volume: 74, Issue:6 Topics: Adult; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Atovaquone; Child; Desensitization, Immunologic; Female; HIV Infections; Humans; Naphthoquinones; Pyrimethamine; Toxoplasmosis, Cerebral	1995
[Therapeutic alternatives for cases of cerebral toxoplasmosis in patients with AIDS: clarithromycin and atovaquone]. Enfermedades infecciosas y microbiologia clinica, 1994, Volume: 12, Issue:3 Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Atovaquone; Clarithromycin; Clindamycin; Drug Therapy, Combination; Folic Acid; Humans; Male; Naphthoquinones; Pyrimethamine; Sulfadiazine; Toxoplasma; Toxoplasmosis, Cerebral	1994
An ultrastructural study of the effect of treatment with atovaquone in brains of mice chronically infected with the ME49 strain of Toxoplasma gondii. International journal of experimental pathology, 1994, Volume: 75, Issue:2 Topics: Animals; Antiprotozoal Agents; Atovaquone; Brain; Chronic Disease; Female; Mice; Mice, Inbred CBA; Microscopy, Electron; Naphthoquinones; Toxoplasmosis, Animal; Toxoplasmosis, Cerebral	1994
Rifabutin is active in murine models of toxoplasmosis. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3 Topics: Animals; Antiprotozoal Agents; Atovaquone; Brain; Clindamycin; Drug Therapy, Combination; Female; Mice; Mice, Inbred CBA; Naphthoquinones; Pyrimethamine; Rifabutin; Sulfadiazine; Toxoplasmosis, Animal; Toxoplasmosis, Cerebral	1994
[Efficacy of atovaquone in resistant toxoplasmosis in AIDS]. Presse medicale (Paris, France : 1983), 1993, Oct-30, Volume: 22, Issue:33 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Antiprotozoal Agents; Atovaquone; Drug Resistance, Microbial; Humans; Naphthoquinones; Toxoplasmosis, Cerebral	1993
Criteria for use of atovaquone oral suspension in adult inpatients and outpatients. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, Nov-01, Volume: 52, Issue:21 Topics: Administration, Oral; Adult; Antifungal Agents; Antiprotozoal Agents; Atovaquone; Clinical Protocols; Drug Monitoring; Humans; Naphthoquinones; Pneumonia, Pneumocystis; Toxoplasmosis, Cerebral	1995
Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:5 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal Agents; Atovaquone; Brain; Clindamycin; Disease Models, Animal; Drug Therapy, Combination; Encephalitis; Female; Mice; Mice, Inbred CBA; Naphthoquinones; Pyrimethamine; Rifabutin; Sulfadiazine; Toxoplasmosis, Cerebral; Treatment Outcome	1996
Clinical features, outcome and survival from cerebral toxoplasmosis in Edinburgh AIDS patients. International journal of STD & AIDS, 1996, Volume: 7, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Atovaquone; Autopsy; Azithromycin; Brain; CD4 Lymphocyte Count; Clindamycin; Drug Therapy, Combination; Female; Humans; Incidence; Lymphoma, AIDS-Related; Male; Middle Aged; Naphthoquinones; Pyrimethamine; Retrospective Studies; Sulfadiazine; Toxoplasmosis, Cerebral; United Kingdom	1996
Effects of drug therapy on Toxoplasma cysts in an animal model of acute and chronic disease. Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:7 Topics: Acute Disease; Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Atovaquone; Brain; Chorioretinitis; Chronic Disease; Cricetinae; Disease Models, Animal; Drug Therapy, Combination; Female; Mesocricetus; Naphthoquinones; Retina; Toxoplasma; Toxoplasmosis, Cerebral; Toxoplasmosis, Ocular	1998