Compounds > atorvastatin
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atorvastatin and Reperfusion Injury

atorvastatin has been researched along with Reperfusion Injury in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (12.77)29.6817
2010's38 (80.85)24.3611
2020's3 (6.38)2.80

Authors

AuthorsStudies
Adeyemi, DH; Afolabi, OA; Akhigbe, RE; Anyogu, DC; Hamed, MA; Odetayo, AF1
Guo, DW; Shih, HC; Wang, CY1
Bi, G; Cao, B; Wang, Y1
Arani, HZ; Jangholi, E; Karimi, A; Movassaghi, S; Parsa, Y; Sharifi, ZN; Yadollah-Damavandi, S1
Abdel-Razek, HAD; Abdou, AG; Hassan, MHA; Hazzaa, SM; Ibraheim, EO; Salem, EA1
Dekker, AM; Heger, M; van Golen, RF; van Gulik, TM; Verheij, J; Wiggers, JK1
Cunha Miranda, JV; de Azevedo Neto, E; de Oliveira Chaves, I; Dias, LDES; Dorsa Pontes, HB; Dourado, DM; Durães Gomes Oliva, JV; Kato da Silva, BA; Marques Dos Santos, CH; Martins de Almeida, MH; Sampaio, TL; Serra da Cruz Vendas, G1
Kerbel, T; Litschauer, B; Weisshaar, S; Wolzt, M1
Erdi, I; Kaya, B; Yasar, M1
Aras, Y; Bagci-Onder, T; Erdag, E; Genc, C; Izgi, N; Tahta, A1
Abdelfattah, S; Ahmad, Z; Hassan, SS; Motawie, A; Rizk, A; Thomann, C1
Hu, JR; Lv, GH; Yin, BL1
Lei, W; Li, H; Tian, J; Wu, K1
Laracuente, ML; Ronaldson, PT; Sanchez-Covarrubias, L; Slosky, LM; Thompson, BJ; Zhang, Y1
Aka Bolat, F; Bulgan Kilicdag, E; Parlakgumus, A; Parlakgumus, HA; Simsek, E1
Alarcón-Galván, G; Cámara-Lemarroy, CR; Cordero-Pérez, P; Fernández-Garza, NE; Guzmán-de la Garza, FJ; Muñoz-Espinosa, L; Torres-González, L1
Cai, J; Ding, X; Fang, Y; Liu, S; Liu, T; Yu, X; Zhang, B; Zhang, H1
Deng, J; He, J; Hu, Z; Lei, Q; Liu, J; Lu, W; Song, T; Tao, X; Zhang, J; Zheng, L1
Deng, JG; Liu, J; Song, T; Tao, X1
Alpay, MF; Cakir, O; Colak, N; Nazli, Y; Uysal, S; Uzunlar, AK1
Ajamieh, H; Chu, E; Farrell, GC; Lam, W; McCuskey, RS; Teoh, NC; Wong, HJ; Yu, J1
Ahmad, A; Khan, MU; Khanam, R; Rohilla, A1
Dong, X; Fang, X; Ji, X; Shen, J; Tao, D; Wang, Y1
Bian, B; Nie, J; Teng, T; Wang, Q; Yu, X1
Caristo, ME; Ciavarella, LP; Citterio, F; Copponi, G; Crea, F; Cusumano, G; Giubilato, S; Liuzzo, G; Manchi, M; Romagnoli, J; Severino, A; Stigliano, E; Zannoni, GF1
Chen, G; Ge, X; Guo, L; Li, K; Luo, L; Shao, S; Xu, M; Zhang, F; Zhou, J; Zhu, Z1
Aykol, S; Civi, S; Kardes, O; Omeroglu, S; Oyar, EO; Tufan, K1
Hua, BJ; Li, HY; Liu, ZQ; Su, YY; Zhang, YF1
Li, HY; Li, YQ; Su, YY; Wang, JL; Wang, Q; Yang, S; Zhang, YF1
Alexandropoulos, D; Arkadopoulos, N; Bazigos, GV; Doulamis, IP; Kondi-Pafiti, A; Konstantopoulos, P; Kotsis, T; Perrea, DN; Smyrniotis, V; Tragotsalou, N; Tzani, A1
Cadirci, E; Coskun, K; Halici, Z; Kilic, C; Nuri Keles, O; Odabasoglu, F; Oral, A; Suleyman, H; Unal, B1
Gaur, V; Kumar, A1
Caballero, F; Elena, M; Fernández, A; Fernández-Checa, JC; García-Ruiz, C; Llacuna, L; Martínez, L; Matías, N; Montfort, CV; Morales, A; Rimola, A1
Harris, KP; Haylor, JL; Huang, Q; Nicholson, ML; Waller, HL; Yang, B1
Barthwal, MK; Dikshit, M; Jain, M; Jyoti, A; Keshari, RS; Khanna, V; Prakash, P; Singh, V1
Bronckers, I; Hopman, MT; Rongen, GA; Smits, P; Thijssen, DH; Wever, KE; Wouters, CW1
Boerman, OC; Frederix, GW; Janssen, CI; Meijer, P; Oyen, WJ; Rongen, GA; Smits, P; Wouters, CW1
Ajamieh, H; Chen, J; Chu, E; Farrell, G; Teoh, N; Wong, HJ; Yu, J1
Gracia-Sancho, J1
Drevenšek, G; Janić, M; Lunder, M; Šabovič, M; Žiberna, L1
Bi, XY; He, X; Yu, XJ; Zang, WJ; Zhao, M1
Mensah, K; Mocanu, MM; Yellon, DM1
Atar, S; Birnbaum, Y; Huang, MH; Lin, Y; Perez-Polo, JR; Uretsky, BF; Ye, Y1
Cetin, A; Igdem, AA; Ozacmak, ID; Ozacmak, VH; Sayan, H1
Birnbaum, Y; Huang, MH; Hughes, MG; Lin, Y; Lui, CY; Manickavasagam, S; McAdoo, DJ; Perez-Polo, RJ; Uretsky, BF; Ye, Y1
Braun, C; Brinkkoetter, PT; Coutinho, ZM; Gottmann, U; Gutermann, K; Hoeger, S; Hui, S; Liu, Z; Ruf, T; Schnuelle, P; van der Woude, FJ; Yard, BA1
Böhm, M; Dirnagl, U; Endres, M; Gertz, K; Huang, P; Laufs, U; Nickenig, G1

Trials

3 trial(s) available for atorvastatin and Reperfusion Injury

ArticleYear
Atorvastatin combined with ticagrelor prevent ischemia-reperfusion induced vascular endothelial dysfunction in healthy young males - A randomized, placebo-controlled, double-blinded study.
    International journal of cardiology, 2018, 03-15, Volume: 255

    Topics: Acetylcholine; Adenosine; Adolescent; Adult; Atorvastatin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Endothelium, Vascular; Forearm; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Purinergic P2Y Receptor Antagonists; Regional Blood Flow; Reperfusion Injury; Ticagrelor; Vasodilation; Young Adult

2018
Short-term statin treatment does not prevent ischemia and reperfusion-induced endothelial dysfunction in humans.
    Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:1

    Topics: 5'-Nucleotidase; Adolescent; Adult; Atorvastatin; Blood Pressure; Brachial Artery; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Female; Fluorobenzenes; Heart Rate; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Middle Aged; Pyrimidines; Pyrroles; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Rosuvastatin Calcium; Sulfonamides; Time Factors; Vasodilation; Young Adult

2012
Atorvastatin does not affect ischaemia-induced phosphatidylserine exposition in humans in-vivo.
    Journal of atherosclerosis and thrombosis, 2012, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Anticholesteremic Agents; Atorvastatin; Cross-Over Studies; Double-Blind Method; Exercise; Forearm; Heptanoic Acids; Humans; Ischemia; Ischemic Preconditioning; Male; Middle Aged; Phosphatidylserines; Pyrroles; Reperfusion Injury; Young Adult

2012

Other Studies

44 other study(ies) available for atorvastatin and Reperfusion Injury

ArticleYear
Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury.
    Redox report : communications in free radical research, 2022, Volume: 27, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Apoptosis; Atorvastatin; Caspase 3; Down-Regulation; Female; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Ischemia; Malondialdehyde; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha; Uric Acid; Vascular Cell Adhesion Molecule-1; Xanthine Oxidase

2022
N-acetylcysteine and atorvastatin alleviates lung injury due to ischemia-reperfusion injury in rats.
    Journal of the Chinese Medical Association : JCMA, 2019, Volume: 82, Issue:12

    Topics: Acetylcysteine; Animals; Atorvastatin; Cytokines; Lung Injury; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2019
Pharmacology of atorvastatin on myocardial ischemia-reperfusion in rats and drug effect analysis.
    Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:5(Special)

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Female; Male; Myocardial Infarction; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2019
Atorvastatin Prevents the Neuron Loss in the Hippocampal Dentate Gyrus Region through its Anti-Oxidant and Anti-Apoptotic Activities.
    CNS & neurological disorders drug targets, 2021, Volume: 20, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Atorvastatin; Brain Ischemia; Cell Death; Dentate Gyrus; Hippocampus; In Situ Nick-End Labeling; Male; Mitochondria; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Reperfusion Injury

2021
Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord.
    Journal of immunoassay & immunochemistry, 2021, Nov-02, Volume: 42, Issue:6

    Topics: Advanced Oxidation Protein Products; Animals; Atorvastatin; bcl-2-Associated X Protein; Carnitine; Catalase; Malondialdehyde; Nitrates; Nitrites; Rats; Reactive Oxygen Species; Reperfusion Injury; Spinal Cord; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2021
Atorvastatin does not protect against ischemia-reperfusion damage in cholestatic rat livers.
    BMC surgery, 2017, Apr-11, Volume: 17, Issue:1

    Topics: Administration, Oral; Animals; Atorvastatin; Bile Ducts; Cholestasis, Extrahepatic; Drug Administration Schedule; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Ligation; Liver; Male; Necrosis; Postoperative Complications; Protective Agents; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Treatment Outcome

2017
Atorvastatin Protects Kidney from Remote Reperfusion Injury.
    Annals of vascular surgery, 2018, Volume: 46

    Topics: Animals; Aorta, Abdominal; Atorvastatin; Combined Modality Therapy; Cytoprotection; Disease Models, Animal; Ischemic Postconditioning; Kidney; Kidney Diseases; Male; Protective Agents; Rats, Wistar; Regional Blood Flow; Reperfusion Injury; Time Factors

2018
The preventive effects of atorvastatin and N-acetyl cysteine in experimentally induced ischemia-reperfusion injury in rats.
    Bratislavske lekarske listy, 2018, Volume: 119, Issue:3

    Topics: Acetylcysteine; Animals; Atorvastatin; Catalase; Cecal Diseases; Cecum; Disease Models, Animal; Female; Free Radical Scavengers; Glutathione Peroxidase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Volvulus; Male; Malondialdehyde; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase

2018
Assessment of the MRI and Behavioral Test Results in a Focal Cerebral Ischemia-Reperfusion Model in the Rat after Separate and Combined Use of Mouse-Derived Neural Progenitor Cells, Human-Derived Neural Progenitor Cells and Atorvastatin.
    Turkish neurosurgery, 2018, Volume: 28, Issue:4

    Topics: Animals; Atorvastatin; Behavior Rating Scale; Disease Models, Animal; Humans; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Mice; Neural Stem Cells; Rats; Recovery of Function; Reperfusion Injury; Stroke

2018
Preconditioning with atorvastatin against renal ischemia-reperfusion injury in nondiabetic versus diabetic rats.
    Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:1

    Topics: Acute Kidney Injury; Animals; Atorvastatin; Diabetes Mellitus, Experimental; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Preconditioning; Kidney Cortex; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2019
Altered microRNA expression in the ischemic-reperfusion spinal cord with atorvastatin therapy.
    Journal of pharmacological sciences, 2013, Volume: 121, Issue:4

    Topics: Animals; Atorvastatin; Disease Models, Animal; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MicroRNAs; Neuroprotective Agents; Pyrroles; Rats; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Spinal Cord; Spinal Cord Ischemia

2013
Atorvastatin treatment attenuates renal injury in an experimental model of ischemia-reperfusion in rats.
    BMC nephrology, 2014, Jan-15, Volume: 15

    Topics: Acute Kidney Injury; Animals; Anticholesteremic Agents; Atorvastatin; Disease Models, Animal; Glomerular Filtration Rate; Heptanoic Acids; Male; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome

2014
Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood-brain barrier: relevance to CNS drug delivery.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:4

    Topics: Animals; Atorvastatin; Biological Transport; Blood Gas Analysis; Blood-Brain Barrier; Blotting, Western; Carbon Dioxide; Drug Delivery Systems; Electrolytes; Female; Heptanoic Acids; Hypoxia, Brain; Microvessels; Neuroprotective Agents; Organic Anion Transporters; Oxygen; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2014
Atorvastatin for ovarian torsion: effects on follicle counts, AMH, and VEGF expression.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 175

    Topics: Animals; Anti-Mullerian Hormone; Atorvastatin; Drug Evaluation, Preclinical; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Ovarian Diseases; Ovarian Follicle; Pyrroles; Rats, Wistar; Reperfusion Injury; Torsion Abnormality; Vascular Endothelial Growth Factor A

2014
Hepatic ischemia/reperfusion injury is diminished by atorvastatin in Wistar rats.
    Archives of medical research, 2014, Volume: 45, Issue:3

    Topics: Animals; Antithrombin III; Atorvastatin; Endothelin-1; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Liver; Male; Pyrroles; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha

2014
Atorvastatin improves survival of implanted stem cells in a rat model of renal ischemia-reperfusion injury.
    American journal of nephrology, 2014, Volume: 39, Issue:6

    Topics: Acute Kidney Injury; Animals; Atorvastatin; Graft Survival; Heptanoic Acids; HMGB1 Protein; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunity, Innate; Inflammation; Kidney; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Oxidative Stress; Pyrroles; Rats; Reperfusion Injury; Toll-Like Receptor 4

2014
HspB8 expression in brain tissue after cerebral ischemic reperfusion and atorvastatin intervention in Sprague-Dawley rats.
    Neurological research, 2015, Volume: 37, Issue:3

    Topics: Animals; Apoptosis; Atorvastatin; Blotting, Western; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Heat-Shock Proteins; Heptanoic Acids; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Pyrroles; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Tetrazolium Salts

2015
Protection effect of atorvastatin in cerebral ischemia-reperfusion injury rats by blocking the mitochondrial permeability transition pore.
    Genetics and molecular research : GMR, 2014, Dec-18, Volume: 13, Issue:4

    Topics: Animals; Anticholesteremic Agents; Apoptosis; Atorvastatin; Brain Ischemia; Cytochromes c; Disease Models, Animal; Heptanoic Acids; Infarction, Middle Cerebral Artery; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Pyrroles; Rats, Sprague-Dawley; Reperfusion Injury

2014
Neuroprotective effect of atorvastatin in spinal cord ischemia-reperfusion injury.
    Clinics (Sao Paulo, Brazil), 2015, Volume: 70, Issue:1

    Topics: Animals; Atorvastatin; Biopsy; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Paraplegia; Pyrroles; Rabbits; Random Allocation; Reperfusion Injury; Reproducibility of Results; Spinal Cord Ischemia; Superoxide Dismutase; Time Factors

2015
Acute atorvastatin is hepatoprotective against ischaemia-reperfusion injury in mice by modulating eNOS and microparticle formation.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:9

    Topics: Animals; Atorvastatin; Chemokines; Cytokines; HMGB1 Protein; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Mice; Mice, Obese; NF-kappa B; Nitric Oxide Synthase Type III; Non-alcoholic Fatty Liver Disease; Reperfusion Injury; Thromboxane B2; Toll-Like Receptor 4; Vascular Cell Adhesion Molecule-1

2015
A comparative study on the cardioprotective potential of atorvastatin and simvastatin in hyperhomocysteinemic rat hearts.
    European journal of pharmacology, 2015, Oct-05, Volume: 764

    Topics: Animals; Atorvastatin; Cardiotonic Agents; Female; Hyperhomocysteinemia; Male; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin

2015
Neuroprotective effects and dynamic expressions of MMP9 and TIMP1 associated with atorvastatin pretreatment in ischemia-reperfusion rats.
    Neuroscience letters, 2015, Aug-31, Volume: 603

    Topics: Animals; Atorvastatin; Brain; Brain Infarction; Brain Ischemia; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; Rats, Sprague-Dawley; Reperfusion Injury; Tissue Inhibitor of Metalloproteinase-1

2015
Atorvastatin protects myocardium against ischemia-reperfusion arrhythmia by increasing Connexin 43 expression: A rat model.
    European journal of pharmacology, 2015, Dec-05, Volume: 768

    Topics: Animals; Arrhythmias, Cardiac; Atorvastatin; Connexin 43; Creatine Kinase, MB Form; Cytoprotection; Disease Models, Animal; Heart Rate; L-Lactate Dehydrogenase; Male; Myocardium; Phosphatidylinositol 3-Kinases; Phosphoproteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Up-Regulation

2015
N-Acetylcysteine and High-Dose Atorvastatin Reduce Oxidative Stress in an Ischemia-Reperfusion Model in the Rat Kidney.
    Transplantation proceedings, 2015, Volume: 47, Issue:9

    Topics: Acetylcysteine; Animals; Atorvastatin; Catalase; Female; Free Radical Scavengers; Glutathione Peroxidase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Kidney Diseases; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Reperfusion Injury; Superoxide Dismutase

2015
Atorvastatin Attenuates Ischemia/Reperfusion-Induced Hippocampal Neurons Injury Via Akt-nNOS-JNK Signaling Pathway.
    Cellular and molecular neurobiology, 2017, Volume: 37, Issue:4

    Topics: Animals; Apoptosis; Atorvastatin; Brain Ischemia; Hippocampus; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Reperfusion Injury

2017
Effects of Atorvastatin on Experimental Spinal Cord Ischemia-Reperfusion Injury in Rabbits.
    Turkish neurosurgery, 2017, Volume: 27, Issue:4

    Topics: Animals; Atorvastatin; Biomarkers; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Rabbits; Reperfusion Injury; Secondary Prevention; Spinal Cord; Spinal Cord Injuries; Spinal Cord Ischemia

2017
Involvement of peroxisome proliferator activated receptor-γ in the anti-inflammatory effects of atorvastatin in oxygen-glucose deprivation/reperfusion-stimulated RAW264.7 murine macrophages.
    Molecular medicine reports, 2016, Volume: 14, Issue:5

    Topics: Animals; Atorvastatin; Disease Models, Animal; Gene Expression Regulation; Gene Knockdown Techniques; Glucose; Humans; Inflammation; Interferon-gamma; Lectins, C-Type; Mannose Receptor; Mannose-Binding Lectins; Mice; Nitric Oxide Synthase Type II; Oxygen; PPAR gamma; RAW 264.7 Cells; Receptors, Cell Surface; Reperfusion Injury; Tumor Necrosis Factor-alpha

2016
Atorvastatin alleviates renal ischemia-reperfusion injury in rats by promoting M1-M2 transition.
    Molecular medicine reports, 2017, Volume: 15, Issue:2

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Atorvastatin; Creatinine; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Interferon-gamma; Kidney; Macrophages; Male; Microscopy, Fluorescence; Mitosis; PPAR gamma; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha; Up-Regulation

2017
Protective effects of N-acetylcystein and atorvastatin against renal and hepatic injury in a rat model of intestinal ischemia-reperfusion.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 89

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Atorvastatin; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestines; Kidney Function Tests; Liver Diseases; Liver Function Tests; Male; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury

2017
Atorvastatin reduces tissue damage in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2010, Volume: 381, Issue:5

    Topics: Animals; Antioxidants; Atorvastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutathione; Heptanoic Acids; Ischemia; Lipid Peroxidation; Ovary; Peroxidase; Pyrroles; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase

2010
Neuroprotective potentials of candesartan, atorvastatin and their combination against stroke induced motor dysfunction.
    Inflammopharmacology, 2011, Volume: 19, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atorvastatin; Behavior, Animal; Benzimidazoles; Biphenyl Compounds; Brain; Brain Ischemia; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mitochondria; Motor Activity; Movement Disorders; Neurons; Organ Specificity; Oxidative Stress; Pyrroles; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Stroke; Tetrazoles

2011
Targeting cholesterol at different levels in the mevalonate pathway protects fatty liver against ischemia-reperfusion injury.
    Journal of hepatology, 2011, Volume: 54, Issue:5

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cholesterol, Dietary; Choline; Choline Deficiency; Disease Models, Animal; Disease Susceptibility; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Fatty Liver; Glutathione; Heptanoic Acids; Lipotropic Agents; Liver; Male; Mevalonic Acid; Mice; Mice, Inbred C57BL; Mitochondria; Obesity; Pyrroles; Quinuclidines; Reperfusion Injury

2011
Atorvastatin improving renal ischemia reperfusion injury via direct inhibition of active caspase-3 in rats.
    Experimental biology and medicine (Maywood, N.J.), 2011, Jun-01, Volume: 236, Issue:6

    Topics: Animals; Apoptosis; Atorvastatin; Caspase Inhibitors; Creatinine; Enzyme Inhibitors; Heptanoic Acids; Kidney Tubules; Metabolic Clearance Rate; Protective Agents; Pyrroles; Rats; Reperfusion Injury

2011
Atorvastatin protects against ischemia-reperfusion injury in fructose-induced insulin resistant rats.
    Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:4

    Topics: Animals; Atorvastatin; Endothelium, Vascular; Fructose; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin Resistance; Male; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Wistar; Reperfusion Injury

2011
Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:8

    Topics: Administration, Oral; Animals; Atorvastatin; Cell Adhesion Molecules; Cytokines; Cytoprotection; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Enzyme Activation; Fatty Liver; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Liver; Male; Mice; Mice, Obese; NF-kappa B; Nitric Oxide Synthase Type III; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Reperfusion Injury; RNA, Messenger; Thromboxane B2; Time Factors; Toll-Like Receptor 4

2012
Enhancing organ pool by statins: is this the future?
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:8

    Topics: Animals; Atorvastatin; Fatty Liver; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Nitric Oxide Synthase Type III; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Reperfusion Injury; Toll-Like Receptor 4

2012
A low-dose atorvastatin and losartan combination directly improves aortic ring relaxation and diminishes ischaemic-reperfusion injury in isolated rat hearts.
    Medical science monitor : international medical journal of experimental and clinical research, 2012, Volume: 18, Issue:9

    Topics: Analysis of Variance; Animals; Aorta; Atorvastatin; Coronary Vessels; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heptanoic Acids; Losartan; Male; Muscle Relaxation; Pyrroles; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion Injury; Treatment Outcome

2012
Role of endothelial nitric oxide synthase and vagal activity in the endothelial protection of atorvastatin in ischemia/reperfusion injury.
    Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:5

    Topics: Acetylcholine; Animals; Apoptosis; Atorvastatin; Endothelium, Vascular; Enzyme Inhibitors; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vagus Nerve; Vasoconstrictor Agents

2013
Failure to protect the myocardium against ischemia/reperfusion injury after chronic atorvastatin treatment is recaptured by acute atorvastatin treatment: a potential role for phosphatase and tensin homolog deleted on chromosome ten?
    Journal of the American College of Cardiology, 2005, Apr-19, Volume: 45, Issue:8

    Topics: Animals; Atorvastatin; Blotting, Western; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Suppressor Proteins

2005
Myocardial protection by pioglitazone, atorvastatin, and their combination: mechanisms and possible interactions.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:3

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation; Heptanoic Acids; Hypoglycemic Agents; Inositol Polyphosphate 5-Phosphatases; Male; Myocardial Infarction; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Phospholipases A; Phospholipases A2; Phosphoric Monoester Hydrolases; Phosphorylation; Pioglitazone; PTEN Phosphohydrolase; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiazolidinediones

2006
Attenuation of contractile dysfunction by atorvastatin after intestinal ischemia reperfusion injury in rats.
    European journal of pharmacology, 2007, May-07, Volume: 562, Issue:1-2

    Topics: Administration, Oral; Animals; Atorvastatin; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Glutathione; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileum; In Vitro Techniques; Intestines; Male; Malondialdehyde; Muscle Contraction; Neurotransmitter Agents; Peroxidase; Potassium Chloride; Pyrroles; Rats; Rats, Wistar; Reperfusion Injury; Substance P

2007
The cardioprotective effect of a statin and cilostazol combination: relationship to Akt and endothelial nitric oxide synthase activation.
    Cardiovascular drugs and therapy, 2007, Volume: 21, Issue:5

    Topics: Adenosine; Administration, Oral; Animals; Atorvastatin; Body Weight; Cilostazol; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Heptanoic Acids; Immunoblotting; Male; Myocardium; Nitric Oxide Synthase Type III; Organ Culture Techniques; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Risk Factors; Tetrazoles; Treatment Outcome

2007
Atorvastatin donor pretreatment prevents ischemia/reperfusion injury in renal transplantation in rats: possible role for aldose-reductase inhibition.
    Transplantation, 2007, Sep-27, Volume: 84, Issue:6

    Topics: Aldehyde Reductase; Animals; Atorvastatin; Gene Expression Profiling; Graft Survival; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Kidney Transplantation; Male; Pyrroles; Rats; Rats, Inbred Strains; Reperfusion Injury

2007
Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice.
    Stroke, 2000, Volume: 31, Issue:10

    Topics: Animals; Aorta; Atorvastatin; beta-Thromboglobulin; Blood Coagulation; Blood Platelets; Brain Ischemia; Cholesterol; Dose-Response Relationship, Drug; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Mice; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Activation; Platelet Factor 4; Pyrroles; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; RNA, Messenger; Up-Regulation

2000