Page last updated: 2024-08-24

atorvastatin and Osteogenic Sarcoma

atorvastatin has been researched along with Osteogenic Sarcoma in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fromigué, O; Girault, I; Habel, N; Hamidouche, Z; Lecanda, F; Marie, PJ; Patiño-García, A1
Huang, Y; Li, X; Zhang, C; Zhao, S1
Fromigué, O; Hamidouche, Z; Marie, PJ2
Barbry, P; Fromigue, O; Hamidouche, Z; Lecanda, F; Mari, B; Marie, PJ; Patino, A; Vaudin, P1
Auberger, P; Bouvet, S; Fromigué, O; Haÿ, E; Jacquel, A; Marie, PJ; Modrowski, D1
Balcells, S; Blanch, J; Carreras, R; Díez-Perez, A; Enjuanes, A; Grinberg, D; Mellibovsky, L; Monllau, JC; Nogues, X; Pedro-Botet, J; Ruiz-Gaspa, S1

Other Studies

7 other study(ies) available for atorvastatin and Osteogenic Sarcoma

ArticleYear
Zinc chelation: a metallothionein 2A's mechanism of action involved in osteosarcoma cell death and chemotherapy resistance.
    Cell death & disease, 2013, Oct-24, Volume: 4

    Topics: Adolescent; Atorvastatin; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Survival; Chelating Agents; Child; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Silencing; Heptanoic Acids; Humans; Metallothionein; Osteoblasts; Osteosarcoma; Prognosis; Protein Conformation; Pyrroles; RNA, Messenger; Tumor Suppressor Protein p53; Zinc

2013
Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells.
    Molecular medicine reports, 2016, Volume: 13, Issue:2

    Topics: Apoptosis; Atorvastatin; Cell Line, Tumor; Cell Movement; Cell Survival; Connective Tissue Growth Factor; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Neoplasm Invasiveness; Osteosarcoma

2016
Blockade of the RhoA-JNK-c-Jun-MMP2 cascade by atorvastatin reduces osteosarcoma cell invasion.
    The Journal of biological chemistry, 2008, Nov-07, Volume: 283, Issue:45

    Topics: Animals; Apoptosis; Atorvastatin; Cell Line, Tumor; Cell Movement; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MAP Kinase Kinase 4; MAP Kinase Signaling System; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Osteosarcoma; Phosphorylation; Proto-Oncogene Proteins c-jun; Pyrroles; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Tissue Inhibitor of Metalloproteinase-2

2008
CYR61 downregulation reduces osteosarcoma cell invasion, migration, and metastasis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, Volume: 26, Issue:7

    Topics: Animals; Apoptosis; Atorvastatin; Bone and Bones; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Cysteine-Rich Protein 61; Down-Regulation; Gene Expression Regulation, Neoplastic; Heptanoic Acids; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Osteosarcoma; Prenylation; Pyrroles

2011
RhoA GTPase inactivation by statins induces osteosarcoma cell apoptosis by inhibiting p42/p44-MAPKs-Bcl-2 signaling independently of BMP-2 and cell differentiation.
    Cell death and differentiation, 2006, Volume: 13, Issue:11

    Topics: Anticholesteremic Agents; Apoptosis; Atorvastatin; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Caspases; Cell Differentiation; Cell Survival; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Heptanoic Acids; Humans; Osteosarcoma; Phenotype; Phosphorylation; Polyisoprenyl Phosphates; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Pyridines; Pyrroles; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction; Simvastatin; Transforming Growth Factor beta

2006
Simvastatin and atorvastatin enhance gene expression of collagen type 1 and osteocalcin in primary human osteoblasts and MG-63 cultures.
    Journal of cellular biochemistry, 2007, Aug-15, Volume: 101, Issue:6

    Topics: Aged; Atorvastatin; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Collagen Type I; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Osteoblasts; Osteocalcin; Osteosarcoma; Pyrroles; Simvastatin; Transforming Growth Factor beta

2007
Statin-induced inhibition of 3-hydroxy-3-methyl glutaryl coenzyme a reductase sensitizes human osteosarcoma cells to anticancer drugs.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Atorvastatin; Cell Line, Tumor; Cell Movement; Cell Survival; Cisplatin; Doxorubicin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Matrix Metalloproteinase 2; Osteosarcoma; Pyrroles

2008