Page last updated: 2024-08-24

atorvastatin and Necrosis

atorvastatin has been researched along with Necrosis in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (33.33)29.6817
2010's13 (61.90)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Sparks, DA; Stiles, ZE1
Dekker, AM; Heger, M; van Golen, RF; van Gulik, TM; Verheij, J; Wiggers, JK1
Hofer, M; Hussenbux, A; Steuer, A1
Essers, D; Kullak-Ublick, GA; Schäublin, M; Weiler, S1
Chang, F; Fu, H; Li, F; Liu, J; Wang, J; Zhao, J; Zhao, WB1
Abushahin, A; Hasan, S; Kilani, A; Prayson, R1
Biondi-Zoccai, G; Calcagno, S; Canali, E; Conti, G; Fedele, F; Lucisano, L; Mancone, M; Pennacchi, M; Sardella, G; Stio, RE1
He, GX; Liu, XL; Xu, HP; Zhao, XJ1
Krossnes, BK; Ljøstad, U; Mygland, Å1
Aussy, A; Boyer, O; Frigerio, S; Hench, J; Kipfer, S1
Gandhi, HP; Patel, SS; Rathod, SP; Trivedi, JI; Variya, BC1
Lóopez-Marure, R; Massó, FA; Montaño, LF; Páez, A; Rodríguez, E; Sánchez, CA; Varela, E; Zapata, E1
Clementi, F; Di Luozzo, M; Luciani, G; Mango, R; Martuscelli, E; Mehta, JL; Pizzuto, F; Romeo, F; Trivisonno, A1
Alegret, M; Ađalsteisson, GS; Laguna, JC; Merlos, M; Rebollo, A; Roglans, N; Vilà, L1
Ghilencea, L; Mario, CD; Moreno-Ambroj, C; Tyczyński, P; Witkowska, AB1
Chu, B; Dong, L; Hatsukami, T; Lane, T; Lee, C; Monick, D; Moore, A; Neradilek, MB; Phan, BA; Polissar, N; Underhill, H; Yuan, C; Zhao, XQ1
Barbosa, E; Pannu, R; Singh, AK; Singh, I1
Iwano, C; Matsuyama, K; Matzno, S; Nishikata, M; Yasuda, N1
Di Sciascio, G; Nusca, A; Pasceri, V; Patti, G1
Balaraman, R; Bothara, SB; Majithiya, JB; Trivedi, CJ1
Braunwald, E1

Reviews

1 review(s) available for atorvastatin and Necrosis

ArticleYear
[Prevention of periprocedural myocardial damage in patients undergoing percutaneous coronary intervention].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2005, Volume: 6, Issue:9

    Topics: Actuarial Analysis; Adenosine; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Atorvastatin; Biomarkers; Clopidogrel; Creatine Kinase, MB Form; Electrocardiography; Embolism; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Placebos; Platelet Aggregation Inhibitors; Prospective Studies; Pyrroles; Randomized Controlled Trials as Topic; Risk Factors; Stents; Ticlopidine; Time Factors; Vasodilator Agents

2005

Trials

2 trial(s) available for atorvastatin and Necrosis

ArticleYear
Comparison of high reloading ROsuvastatin and Atorvastatin pretreatment in patients undergoing elective PCI to reduce the incidence of MyocArdial periprocedural necrosis. The ROMA II trial.
    International journal of cardiology, 2013, Oct-09, Volume: 168, Issue:4

    Topics: Aged; Angina, Stable; Atorvastatin; Elective Surgical Procedures; Female; Fluorobenzenes; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Middle Aged; Myocardial Infarction; Necrosis; Percutaneous Coronary Intervention; Postoperative Complications; Preoperative Care; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Treatment Outcome

2013
MR imaging of carotid plaque composition during lipid-lowering therapy a prospective assessment of effect and time course.
    JACC. Cardiovascular imaging, 2011, Volume: 4, Issue:9

    Topics: Apolipoproteins B; Atorvastatin; Biomarkers; Calcium; Carotid Arteries; Carotid Artery Diseases; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Fibrosis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Idaho; Lipid Metabolism; Magnetic Resonance Angiography; Male; Middle Aged; Necrosis; Predictive Value of Tests; Prospective Studies; Pyrroles; Time Factors; Treatment Outcome; Washington

2011

Other Studies

18 other study(ies) available for atorvastatin and Necrosis

ArticleYear
Acute Extremity Compartment Syndrome Secondary to Statin-Induced Myopathy.
    The American surgeon, 2017, Mar-01, Volume: 83, Issue:3

    Topics: Anticholesteremic Agents; Atorvastatin; Compartment Syndromes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leg; Male; Middle Aged; Muscular Diseases; Necrosis

2017
Atorvastatin does not protect against ischemia-reperfusion damage in cholestatic rat livers.
    BMC surgery, 2017, Apr-11, Volume: 17, Issue:1

    Topics: Administration, Oral; Animals; Atorvastatin; Bile Ducts; Cholestasis, Extrahepatic; Drug Administration Schedule; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Ligation; Liver; Male; Necrosis; Postoperative Complications; Protective Agents; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Treatment Outcome

2017
Statin-induced necrotizing autoimmune myopathy: importance of early recognition.
    British journal of hospital medicine (London, England : 2005), 2017, Jun-02, Volume: 78, Issue:6

    Topics: Aged; Atorvastatin; Autoimmune Diseases; Creatine Kinase; Early Diagnosis; Female; Glucocorticoids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle, Skeletal; Muscular Diseases; Necrosis; Prednisolone

2017
Statin-associated immune-mediated necrotizing myopathy: a retrospective analysis of individual case safety reports from VigiBase.
    European journal of clinical pharmacology, 2019, Volume: 75, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Atorvastatin; Autoantibodies; Autoimmune Diseases; Creatine Kinase; Databases, Factual; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Muscular Diseases; Necrosis

2019
Effects of various doses of atorvastatin on vascular endothelial cell apoptosis and autophagy in vitro.
    Molecular medicine reports, 2019, Volume: 19, Issue:3

    Topics: Apoptosis; Atorvastatin; Autophagy; Biomarkers; Cell Shape; Cell Survival; Cell Transdifferentiation; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; Necrosis; Neurons

2019
When Statins Cause an Autoimmune Response: A Report of a Severe Case of Rhabdomyolysis.
    The American journal of medicine, 2020, Volume: 133, Issue:1

    Topics: Aged; Atorvastatin; Autoantibodies; Autoimmune Diseases; Azathioprine; Creatine Kinase; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulins, Intravenous; Immunologic Factors; Male; Muscle, Skeletal; Muscular Diseases; Myoglobin; Necrosis; Prednisone; Rhabdomyolysis; Severity of Illness Index

2020
Effects of single-dose atorvastatin on interleukin-6, interferon gamma, and myocardial no-reflow in a rabbit model of acute myocardial infarction and reperfusion.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2014, Volume: 47, Issue:3

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Coronary Occlusion; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Immunohistochemistry; Inflammation; Interferon-gamma; Interleukin-6; Ligation; Male; Multivariate Analysis; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Necrosis; No-Reflow Phenomenon; Pyrroles; Rabbits; Random Allocation

2014
Persisting weakness after withdrawal of a statin.
    BMJ case reports, 2014, Apr-08, Volume: 2014

    Topics: Aged, 80 and over; Atorvastatin; Autoimmune Diseases; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Weakness; Myositis; Necrosis; Pyrroles

2014
Immune-mediated necrotising myopathy linked to statin use.
    Lancet (London, England), 2015, Oct-31, Volume: 386, Issue:10005

    Topics: Atorvastatin; Autoimmune Diseases; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging; Male; Middle Aged; Muscle, Skeletal; Muscular Diseases; Necrosis

2015
Comparative evaluation of HMG CoA reductase inhibitors in experimentally-induced myocardial necrosis: Biochemical, morphological and histological studies.
    European journal of pharmacology, 2015, Oct-05, Volume: 764

    Topics: Adenosine Triphosphatases; Animals; Atorvastatin; Blood Glucose; Cardiotonic Agents; Catalase; Cholesterol; Fatty Acids, Monounsaturated; Fluvastatin; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Isoproterenol; Male; Myocardial Infarction; Myocardium; Necrosis; Pravastatin; Rats, Wistar; Rosuvastatin Calcium; Simvastatin; Superoxide Dismutase; Triglycerides

2015
Statin-induced inhibition of MCF-7 breast cancer cell proliferation is related to cell cycle arrest and apoptotic and necrotic cell death mediated by an enhanced oxidative stress.
    Cancer investigation, 2008, Volume: 26, Issue:7

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Atorvastatin; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Proliferation; DNA Replication; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Membrane Potential, Mitochondrial; Necrosis; Oxidative Stress; Pyrroles; Reactive Oxygen Species; Simvastatin

2008
Regression and shift in composition of coronary atherosclerotic plaques by pioglitazone: insight from an intravascular ultrasound analysis.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2009, Volume: 10, Issue:3

    Topics: Aged; Atorvastatin; Calcinosis; Coronary Artery Disease; Diabetes Mellitus; Drug Therapy, Combination; Female; Fibrosis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Middle Aged; Necrosis; Pilot Projects; Pioglitazone; Prospective Studies; Pyrroles; Registries; Thiazolidinediones; Time Factors; Treatment Outcome; Ultrasonography, Interventional; User-Computer Interface

2009
Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment.
    Toxicology and applied pharmacology, 2011, Feb-15, Volume: 251, Issue:1

    Topics: Animals; Atorvastatin; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cyclic AMP-Dependent Protein Kinases; Dietary Carbohydrates; Disease Models, Animal; Down-Regulation; Fatty Acids; Fatty Liver; Fructokinases; Fructose; Gene Expression Regulation; Hepatitis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; I-kappa B Proteins; Inflammation Mediators; Lipid Metabolism; Liver; Male; Metallothionein; Necrosis; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Triglycerides

2011
Long term observation of thin-cap fibroatheroma by optical coherence tomography.
    Cardiology journal, 2010, Volume: 17, Issue:6

    Topics: Atorvastatin; Coronary Artery Disease; Coronary Vessels; Fibrosis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Necrosis; Pyrroles; Time Factors; Tomography, Optical Coherence; Treatment Outcome

2010
Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats.
    Journal of neuroscience research, 2005, Feb-01, Volume: 79, Issue:3

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Disease Models, Animal; Female; Gliosis; Heptanoic Acids; Interleukin-1; Motor Activity; Myelitis; Necrosis; Nerve Degeneration; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligodendroglia; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Treatment Outcome; Tumor Necrosis Factor-alpha

2005
Evaluation of apoptosis and necrosis induced by statins using fluorescence-enhanced flow cytometry.
    Journal of pharmaceutical and biomedical analysis, 2005, Sep-15, Volume: 39, Issue:3-4

    Topics: Apoptosis; Atorvastatin; Avidin; Biotin; Cell Line; Cell Separation; Cells, Cultured; Drug Industry; Drug Screening Assays, Antitumor; Fatty Acids, Monounsaturated; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Leukemia; Microscopy, Fluorescence; Necrosis; Pharmaceutical Preparations; Pravastatin; Propidium; Pyridines; Pyrroles; Simvastatin; Time Factors

2005
Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats.
    Pharmacology, 2006, Volume: 77, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Atorvastatin; Body Weight; Catalase; Glutathione; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction; Myocardium; Necrosis; Organ Size; Pyrroles; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2006
Reducing myocardial injury by minimizing imbalance between oxygen supply and demand.
    Anesthesiology, 2007, Volume: 107, Issue:1

    Topics: Anesthesiology; Animals; Atorvastatin; Blood Pressure; Cardiovascular Agents; Coronary Disease; Dogs; Heart Diseases; Heart Rate; Heptanoic Acids; History, 20th Century; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Myocardial Revascularization; Necrosis; Oxygen; Pyrroles

2007