Page last updated: 2024-08-24

atorvastatin and Myocardial Ischemia

atorvastatin has been researched along with Myocardial Ischemia in 83 studies

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (6.02)18.2507
2000's48 (57.83)29.6817
2010's28 (33.73)24.3611
2020's2 (2.41)2.80

Authors

AuthorsStudies
Du, X; Nie, J; Wang, G; Yang, Q; Zhang, L; Zhao, G1
Badimon, L; Ben-Aicha, S; Casani, L; Mendieta, G; Sabate, M; Vilahur, G2
Bi, G; Cao, B; Wang, Y1
Chen, Y; Chen, YY; Cheng, HJ; Chiu, KY; Yuan, YT; Zeng, HQ; Zhang, XB1
Kochubiei, O; Ovrakh, T; Serik, S1
Liu, G; Yang, C; Yang, H; Yang, P; Yang, S; Zhao, D; Zheng, H1
Chrysohoou, C; Dilaveris, P; Kioufis, S; Maniatis, K; Michalea, S; Miliou, A; Oikonomou, E; Papavassiliou, AG; Siasos, G; Stefanadis, C; Tousoulis, D; Zaromitidou, M1
Bianchi, C; Chu, LM; Elmadhun, NY; Sabe, AA; Sadek, AA; Sellke, FW1
Bianchi, C; Chu, LM; Dalal, RS; Elmadhun, NY; Sabe, AA; Sadek, AA; Sellke, FW1
Athanasiou, D; Chrysohoou, C; Hatzis, G; Mazaris, S; Mourouzis, K; Oikonomou, E; Papavassiliou, AG; Siasos, G; Stefanadis, C; Tourikis, P; Tousoulis, D; Zaromitidou, M; Zisimos, K1
Chen, ZC; Cheng, KL; Cheng, SY; Guo, YZ; Ou, MD; Wang, Q; Xue, JJ; Zeng, WJ; Zhang, YT1
El Desoky, ES; Fadil, SA; Hassan, AKM; Salem, SY; Taha, AF1
Alboim, C; Almeida, AP; Barbosa, RR; Berwanger, O; Carmona, MJ; Damiani, L; de Barros E Silva, PG; de Oliveira Filho, JB; Devereaux, PJ; Dracoulakis, MD; Figueiredo, EL; Filho, HV; Gonzales, B; Hajjar, LA; Ikeoka, DT; Kodama, AA; Kruel, CD; Lopes, RD; Maia, LN; Paisani, D; Precoma, DB; Saraiva, JF; Soares, RM1
Gromnaky, NI; Mikhin, VP; Zhilyaeva, YA1
Climent, VE; Lip, GY; López-Cuenca, A; Marín, F; Roldán, V; Valdés, M1
Császár, A1
Braunwald, E; Cannon, CP; Giraldez, RR; Giugliano, RP; McCabe, CH; Mohanavelu, S; Murphy, SA1
Kukhrchuk, VV; Nasonov, EL; Novikova, DS; Popkova, TV; Tutunov, VS1
Karadağ, B; Ongen, Z; Yilmaz, Y1
Ageev, FT; Kulev, BD1
Gerasimidis, T; Kadoglou, NP; Kapelouzou, A; Liapis, CD; Moumtzouoglou, A; Sailer, N1
Chang, SA; Kim, DH; Kim, HK; Kim, YJ; Oh, BH; Park, YB; Sohn, DW1
Colivicchi, F; Genovesi Ebert, A; Melina, G; Mocini, D; Santini, M; Strano, S; Tubaro, M; Uguccioni, M1
Abuladze, GV; Dundua, GI; Dzhindzholiia, NR; Nebieridze, MI1
Beckerman, B; Buch, J; Bultas, J; Deanfield, JE; Sellier, P; Shi, H; Thaulow, E; Yunis, C1
Dereli, Y; Ege, E; Kurban, S; Sarigül, A1
Kukes, IV; Paukov, SV; Ruvinov, IuV; Sivkov, AS1
Kiiakbaev, GK; Kobalava, ZhD; Moiseev, VS; Ozova, EM1
Azizova, OA; Baranova, OA; Blagodatskikh, KA; Koroleva, OS; Nosikov, VV; Pushkov, AA; Reznichenko, NE; Zateĭshchikov, DA1
Bao, W; Benessiano, J; Mallat, Z; Olsson, AG; Ryu, SK; Schwartz, GG; Tedgui, A; Tsimikas, S1
Wang, H; Ye, P; Zhang, JY1
Lazareva, NV; Oshchepkova, EV1
Chu, LM; Elmadhun, NY; Feng, J; Lassaletta, AD; Liu, Y; Sellke, FW1
Supanich, B1
Chaitman, BR; Ezekowitz, M; Ganz, P; Leslie, SJ; Oliver, MF; Olsson, AG; Schwartz, GG; Stern, T; Waters, DD; Zeiher, A1
Bell, RM; Yellon, DM1
Buller, N; Casciano, R; Doyle, J; Gillen, D; Wilson, K1
Correia, LC; D'Oliveira, A; Esteves, JP; Magalhães, LP; Passos, LC; Rocha, MS; Santana, O; Spósito, AC1
Bao, Y; Bernard, SA; Lazar, HL; Zhang, Y1
Betteridge, DJ; Colhoun, HM; Durrington, PN; Fuller, JH; Hitman, GA; Julier, K; Mackness, MI; Neil, HA; Soedamah-Muthu, SS; Thomason, MJ1
Akhmedzhanov, NM; Metel'kaya, VA; Oganov, RG; Raszzivin, VA; Vasiutina, EI1
Belousov, IuB; Leonova, MV1
Arikian, S; Ganz, P; Schwartz, GG; Waters, D1
Arsenault, M; Auclair, L; Bogaty, P; Boyer, L; Dagenais, GR; Jobin, J; Pépin, G; Poirier, P1
Gathof, BS; Gresser, U1
Carlson, W; Clark, ME; Creager, M; Frei, B; Johnstone, M; Kinlay, S; Lloyd-Jones, DM; Maccallum, G; Orav, J; Rubenstein, J; Selwyn, AP; Sopko, G; Stone, PH1
Carlier, M; Claeys, MJ; Cools, F; Cosyns, B; De Meester, A; Dewit, B; Gobin, E; Hoffer, E; Missault, L; Vermeersch, P1
McGowan, MP1
Davidson, MH1
Deedwania, PC1
Ezekowitz, MD; Ganz, P; Oliver, MF; Olsson, AG; Sasiela, WJ; Schwartz, GG; Szarek, M; Waters, D; Zeiher, A1
Andrews, TC; Carlson, W; Cole, H; Creager, MA; Frei, B; Johnstone, M; Kinlay, S; Lloyd-Jones, DM; Orav, J; Rubenstein, J; Selwyn, AP; Sopko, G; Stone, PH1
Ahn, JY; Choi, IS; Chung, WJ; Han, SH; Koh, KK; Quon, MJ; Seo, YH; Shin, EK1
Olsson, AG; Sasiela, WJ; Schwartz, GG; Szarek, M1
Fonarow, GC1
Babkin, AA; Iliukhin, OV; Kalganova, EL; Lopatin, IuM1
Blazing, M; Braunwald, E; Califf, R; Cannon, CP; de Lemos, JA; McCabe, CH; Murphy, SA; Wiviott, SD1
Brown, BG1
Bianchi, C; Boodhwani, M; Feng, J; Laham, R; Li, J; Mieno, S; Nakai, Y; Ramlawi, B; Sellke, FW; Voisine, P1
Daida, H; Hiro, T; Kimura, T; Matsuzaki, M; Miyauchi, K; Morimoto, T; Nakagawa, Y; Ozaki, Y; Yamagishi, M1
Birnbaum, Y; Huang, MH; Lin, Y; Lui, CY; Martinez, JD; Perez-Polo, JR; Uretsky, BF; Ye, Y1
Bairey Merz, CN; Cosin-Aguilar, J; Deedwania, P; Koylan, N; Luo, D; Ouyang, P; Piotrowicz, R; Schenck-Gustafsson, K; Sellier, P; Stein, JH; Stone, PH; Thompson, PL; Tzivoni, D1
Gotto, AM1
Jamieson, MJ; Luo, D; Olsson, AG; Schwartz, GG; Szarek, M1
Prigent, B1
Ezhov, MV; Kukharchuk, VV; Naumov, VG; Samoĭlenko, EIu; Sergienko, IV; Tvorogova, MG1
Balakhonova, TV; Kukharchuk, VV; Kulev, BD; Masenko, VP; Pogorelova, OA; Rogozova, AN; Rozhkova, TA; Susekov, AV; Tripoten', MI; Zubareva, MIu1
Braunwald, E1
Arca, M; Gaspardone, A1
Boodhwani, M; Clements, RT; Feng, J; Mieno, S; Sellke, FW; Sodha, NR; Xu, SH1
Garner, J; Gould, KL; McLain, R; Sdringola, S; Zamarka, LG1
Ameliushkina, VA; Kaminnyĭ, AI; Korotaeva, AA; Kucharchuk, VV; Naumov, VG; Pirkova, AA; Prokazova, NV; Samoĭlova, EV; Titov, VN1
Black, D; Chaitman, BR; Ezekowitz, MD; Ganz, P; Kane, JP; Oliver, MF; Olsson, AG; Pressler, ML; Schwartz, GG; Texter, M; Waters, D1
Brown, WV; Eisenberg, D; McCormick, LS; Pitt, B; Schwartz, L; Shurzinske, L; Title, LM; van Boven, AJ; Waters, D1
Baim, DS; Carrozza, JP; Cohen, DJ1
Hoshi, K; Ichihara, K; Satoh, K; Yamamoto, A1
Blumenthal, RS; Cohn, G; Schulman, SP1
Scheen, AJ1
Puel, J1
de la Iglesia Martínez, F; Diz-Lois Martínez, F; Nicolás Miguel, R; Pellicer Vázquez, C; Pita Fernández, S; Ramos Polledo, V1
Alexander, S; Bilodeau, T; Carlson, W; Clark, M; Johnstone, M; Karam, C; Kinlay, S; Lloyd-Jones, DM; Orav, J; Ridker, PM; Rifai, N; Rubenstein, J; Stone, PH; Timms, T1

Reviews

8 review(s) available for atorvastatin and Myocardial Ischemia

ArticleYear
[Important aim of statin therapy: ischemic cardiovascular event (stroke)].
    Ideggyogyaszati szemle, 2008, Jul-30, Volume: 61, Issue:7-8

    Topics: Acute Disease; Atorvastatin; Brain Ischemia; Cholesterol, LDL; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Meta-Analysis as Topic; Myocardial Ischemia; Pyrroles; Recurrence; Stroke

2008
[Atorvastatin in secondary prevention].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2009, Volume: 37 Suppl 2

    Topics: Acute Coronary Syndrome; Atorvastatin; Coronary Disease; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Pyrroles; Secondary Prevention; Stroke

2009
[Efficacy of atorvastatin in long-term treatment of patients with ischemic heart disease].
    Kardiologiia, 2003, Volume: 43, Issue:4

    Topics: Atorvastatin; Drug Administration Schedule; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Pyrroles; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome

2003
Atorvastatin: gold standard for prophylaxis of myocardial ischemia and stroke - comparison of the clinical benefit of statins on the basis of randomized controlled endpoint studies.
    European journal of medical research, 2004, Jan-26, Volume: 9, Issue:1

    Topics: Anticholesteremic Agents; Atorvastatin; Heptanoic Acids; Humans; Myocardial Ischemia; Pyrroles; Randomized Controlled Trials as Topic; Stroke

2004
In-hospital initiation of statin therapy in acute coronary syndromes: maximizing the early and long-term benefits.
    Chest, 2005, Volume: 128, Issue:5

    Topics: Angina, Unstable; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Myocardial Ischemia; Pravastatin; Pyrroles; Syndrome; Treatment Outcome

2005
Atorvastatin efficacy in the primary and secondary prevention of cardiovascular events.
    Drugs, 2007, Volume: 67 Suppl 1

    Topics: Angioplasty, Balloon; Atorvastatin; Cholesterol, LDL; Coronary Disease; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Myocardial Infarction; Myocardial Ischemia; Pyrroles

2007
Medical therapy versus coronary angioplasty in stable coronary artery disease: a critical review of the literature.
    Journal of the American College of Cardiology, 2000, Volume: 36, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Atorvastatin; Coronary Disease; Heptanoic Acids; Humans; Myocardial Ischemia; Myocardial Revascularization; Pyrroles; Randomized Controlled Trials as Topic

2000
[Statins and unstable angina: MIRACL].
    Annales d'endocrinologie, 2001, Volume: 62, Issue:1 Pt 2

    Topics: Angina, Unstable; Anticholesteremic Agents; Atorvastatin; Cholesterol; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Pyrroles

2001

Trials

36 trial(s) available for atorvastatin and Myocardial Ischemia

ArticleYear
[IMPACT OF ATORVASTATIN AND ROSUVASTATIN ON RESIDUAL ON-CLOPIDOGREL TREATMENT PLATELET REACTIVITY IN PATIENTS WITH ISCHEMIC HEART DISEASE AND TYPE 2 DIABETES MELLITUS AFTER ACUTE CORONARY SYNDROME].
    Georgian medical news, 2017, Issue:265

    Topics: Acute Coronary Syndrome; Aspirin; Atorvastatin; Blood Platelets; Clopidogrel; Diabetes Mellitus, Type 2; Drug Interactions; Drug Substitution; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Rosuvastatin Calcium; Ticlopidine

2017
Dose-dependent effects of short term atorvastatin treatment on arterial wall properties and on indices of left ventricular remodeling in ischemic heart failure.
    Atherosclerosis, 2013, Volume: 227, Issue:2

    Topics: Aged; Arteries; Atorvastatin; Cholesterol, LDL; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Male; Matrix Metalloproteinase 9; Middle Aged; Myocardial Ischemia; Natriuretic Peptide, Brain; Pyrroles; Regression Analysis; Ventricular Remodeling

2013
Atorvastatin treatment improves endothelial function through endothelial progenitor cells mobilization in ischemic heart failure patients.
    Atherosclerosis, 2015, Volume: 238, Issue:2

    Topics: AC133 Antigen; Aged; Aged, 80 and over; Antigens, CD; Antigens, CD34; Atorvastatin; Biomarkers; Brachial Artery; Cell Movement; Cross-Over Studies; Double-Blind Method; Endothelial Progenitor Cells; Endothelium, Vascular; Female; Glycoproteins; Greece; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Male; Middle Aged; Myocardial Ischemia; Peptides; Pyrroles; Recovery of Function; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor Receptor-2; Vasodilation

2015
Atorvastatin for high-risk statin-naïve patients undergoing noncardiac surgery: The Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose (LOAD) randomized trial.
    American heart journal, 2017, Volume: 184

    Topics: Aged; Atorvastatin; Electrocardiography; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Perioperative Care; Postoperative Complications; Proportional Hazards Models; Risk Assessment; Stroke; Surgical Procedures, Operative; Troponin

2017
Effects of atorvastatin 80 mg daily on indices of matrix remodelling in 'high-risk' patients with ischemic heart disease.
    International journal of cardiology, 2010, Feb-18, Volume: 139, Issue:1

    Topics: Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Matrix Metalloproteinase 1; Myocardial Ischemia; Pyrroles; Risk Factors; Tissue Inhibitor of Metalloproteinase-1; Treatment Outcome

2010
Baseline low-density lipoprotein cholesterol is an important predictor of the benefit of intensive lipid-lowering therapy: a PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) analysis.
    Journal of the American College of Cardiology, 2008, Sep-09, Volume: 52, Issue:11

    Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Female; Heptanoic Acids; Humans; Male; Middle Aged; Myocardial Ischemia; Patient Selection; Pravastatin; Pyrroles; Treatment Outcome

2008
[Comparative assessment of antiinflammatory action of atorvastatin in ischemic heart disease and rheumatoid arthritis].
    Kardiologiia, 2008, Volume: 48, Issue:9

    Topics: Arthritis, Rheumatoid; Atorvastatin; C-Reactive Protein; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Prospective Studies; Pyrroles; Treatment Outcome

2008
[Effect of various approaches to therapy with statins in high risk patients from the point of view of vascular endothelium].
    Kardiologiia, 2009, Volume: 49, Issue:5

    Topics: Aged; Atorvastatin; Brachial Artery; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipids; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Risk Factors; Treatment Outcome; Ultrasonography; Vasodilation

2009
Aggressive lipid-lowering is more effective than moderate lipid-lowering treatment in carotid plaque stabilization.
    Journal of vascular surgery, 2010, Volume: 51, Issue:1

    Topics: Aged; Atorvastatin; Biomarkers; C-Reactive Protein; Carotid Stenosis; Cerebrovascular Disorders; Cholesterol, LDL; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Osteopontin; Osteoprotegerin; Prospective Studies; Pyrroles; Severity of Illness Index; Time Factors; Treatment Outcome; Ultrasonography, Doppler

2010
Persistent regional diastolic dysfunction after myocardial ischemia and the effect of statin treatment: assessment with two-dimensional radial strain rate.
    Echocardiography (Mount Kisco, N.Y.), 2010, Volume: 27, Issue:3

    Topics: Angina Pectoris, Variant; Atorvastatin; Diastole; Exercise Test; Female; Fluorobenzenes; Heart; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Pyrimidines; Pyrroles; Reference Standards; Rosuvastatin Calcium; Sulfonamides; Ultrasonography; Ventricular Dysfunction, Left

2010
Full-dose atorvastatin versus conventional medical therapy after non-ST-elevation acute myocardial infarction in patients with advanced non-revascularisable coronary artery disease.
    Current medical research and opinion, 2010, Volume: 26, Issue:6

    Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Italy; Male; Myocardial Infarction; Myocardial Ischemia; Pyrroles; Recurrence; Treatment Outcome

2010
Potent anti-ischaemic effects of statins in chronic stable angina: incremental benefit beyond lipid lowering?
    European heart journal, 2010, Volume: 31, Issue:21

    Topics: Aged, 80 and over; Amlodipine; Angina, Stable; Antihypertensive Agents; Atorvastatin; Chronic Disease; Double-Blind Method; Drug Combinations; Electrocardiography, Ambulatory; Exercise Test; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Young Adult

2010
[Effect of carvedilol and metoprolol R administered with or without atorvastatin on elastic properties of vascular wall and parameters of inflammation in patients with chronic heart failure of ischemic origin].
    Kardiologiia, 2011, Volume: 51, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Anticholesteremic Agents; Arterioles; Atorvastatin; Blood Pressure; C-Reactive Protein; Carbazoles; Carvedilol; Chronic Disease; Drug Therapy, Combination; Elasticity; Female; Heart Failure; Heptanoic Acids; Humans; Interleukin-6; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Propanolamines; Pyrroles; Stroke Volume; Treatment Outcome; Tumor Necrosis Factor-alpha; Vascular Resistance

2011
Effects of atorvastatin on stroke in patients with unstable angina or non-Q-wave myocardial infarction: a Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy.
    Circulation, 2002, Sep-24, Volume: 106, Issue:13

    Topics: Acute Disease; Aged; Angina, Unstable; Anticholesteremic Agents; Atorvastatin; Cholesterol; Electrocardiography; Female; Follow-Up Studies; Heptanoic Acids; Humans; Incidence; Lipids; Male; Myocardial Infarction; Myocardial Ischemia; Proportional Hazards Models; Pyrroles; Risk; Risk Assessment; Secondary Prevention; Stroke; Treatment Outcome

2002
A pharmacoeconomic evaluation of the Myocardial Ischaemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study in the United Kingdom.
    PharmacoEconomics, 2003, Volume: 21 Suppl 1

    Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol; Cohort Studies; Cost-Benefit Analysis; Double-Blind Method; Endpoint Determination; Health Care Costs; Heptanoic Acids; Hospitalization; Humans; Hypercholesterolemia; Myocardial Ischemia; Pyrroles; Treatment Outcome; United Kingdom

2003
Effect of atorvastatin (80 mg) on recurrent ischemia in unstable angina pectoris or non-ST-elevation acute myocardial infarction.
    The American journal of cardiology, 2003, Jun-01, Volume: 91, Issue:11

    Topics: Angina, Unstable; Anticholesteremic Agents; Atorvastatin; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography, Ambulatory; Female; Heptanoic Acids; Humans; Logistic Models; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Pyrroles; Recurrence; Treatment Outcome

2003
The effect of atorvastatin on serum lipids, lipoproteins and NMR spectroscopy defined lipoprotein subclasses in type 2 diabetic patients with ischaemic heart disease.
    Atherosclerosis, 2003, Volume: 167, Issue:2

    Topics: Aged; Atorvastatin; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Magnetic Resonance Spectroscopy; Male; Middle Aged; Myocardial Ischemia; Patient Compliance; Probability; Pyrroles; Reference Values; Risk Assessment; Treatment Outcome

2003
Effect of atorvastatin on exercise-induced myocardial ischemia in patients with stable angina pectoris.
    The American journal of cardiology, 2003, Nov-15, Volume: 92, Issue:10

    Topics: Aged; Angina, Unstable; Atorvastatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Exercise Test; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Male; Middle Aged; Myocardial Ischemia; Pyrroles

2003
Vascular basis for the treatment of myocardial ischemia study: trial design and baseline characteristics.
    American heart journal, 2004, Volume: 147, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Antioxidants; Ascorbic Acid; Atorvastatin; Brachial Artery; Cholesterol, LDL; Double-Blind Method; Female; Heptanoic Acids; Humans; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Regional Blood Flow; Ultrasonography; Vasodilation; Vitamin E

2004
Short-term effect of atorvastatin on ischaemic threshold in hypercholesterolaemic patients with stable ischaemic heart disease.
    Acta cardiologica, 2004, Volume: 59, Issue:3

    Topics: Aged; Angina Pectoris; Atorvastatin; Cholesterol, LDL; Disease Progression; Exercise Test; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Myocardial Ischemia; Pyrroles; Time Factors

2004
There is no evidence for an increase in acute coronary syndromes after short-term abrupt discontinuation of statins in stable cardiac patients.
    Circulation, 2004, Oct-19, Volume: 110, Issue:16

    Topics: Acute Disease; Atorvastatin; Coronary Disease; Disease-Free Survival; Double-Blind Method; Heart Arrest; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Life Tables; Myocardial Infarction; Myocardial Ischemia; Pyrroles; Stroke; Substance Withdrawal Syndrome; Syndrome; Withholding Treatment

2004
High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: results from the MIRACL trial.
    European heart journal, 2005, Volume: 26, Issue:9

    Topics: Aged; Angina, Unstable; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Double-Blind Method; Female; Heptanoic Acids; Humans; Lipoproteins, HDL; Male; Myocardial Infarction; Myocardial Ischemia; Prognosis; Proportional Hazards Models; Pyrroles; Recurrence

2005
Effect of intensive lipid lowering, with or without antioxidant vitamins, compared with moderate lipid lowering on myocardial ischemia in patients with stable coronary artery disease: the Vascular Basis for the Treatment of Myocardial Ischemia Study.
    Circulation, 2005, Apr-12, Volume: 111, Issue:14

    Topics: Angina Pectoris; Antioxidants; Ascorbic Acid; Atorvastatin; Coronary Artery Disease; Diet Therapy; Dose-Response Relationship, Drug; Exercise Test; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lipids; Lipoproteins, LDL; Male; Myocardial Ischemia; Pyrroles; Vasomotor System; Vitamin E

2005
Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia.
    Journal of the American College of Cardiology, 2005, May-17, Volume: 45, Issue:10

    Topics: Arteriosclerosis; Atorvastatin; Brachial Artery; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Fenofibrate; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipids; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Treatment Outcome; Ultrasonography

2005
Relation of characteristics of metabolic syndrome to short-term prognosis and effects of intensive statin therapy after acute coronary syndrome: an analysis of the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) trial.
    Diabetes care, 2005, Volume: 28, Issue:10

    Topics: Acute Disease; Aged; Atorvastatin; Coronary Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Male; Metabolic Syndrome; Middle Aged; Myocardial Ischemia; Predictive Value of Tests; Prognosis; Pyrroles; Recurrence; Risk Factors; Treatment Outcome

2005
[Changes of elastic properties of magistral arteries in patients with ischemic heart disease during treatment with atorvastatin and simvastatin].
    Kardiologiia, 2005, Volume: 45, Issue:12

    Topics: Anticholesteremic Agents; Arteries; Atorvastatin; Carotid Arteries; Cholesterol; Data Interpretation, Statistical; Elasticity; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperemia; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Myocardial Ischemia; Pyrroles; Radial Artery; Simvastatin; Time Factors; Triglycerides

2005
Japan assessment of pitavastatin and atorvastatin in acute coronary syndrome (JAPAN-ACS): rationale and design.
    Circulation journal : official journal of the Japanese Circulation Society, 2006, Volume: 70, Issue:12

    Topics: Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Myocardial Ischemia; Pyrroles; Quinolines; Research Design; Syndrome

2006
Effects of intensive versus moderate lipid-lowering therapy on myocardial ischemia in older patients with coronary heart disease: results of the Study Assessing Goals in the Elderly (SAGE).
    Circulation, 2007, Feb-13, Volume: 115, Issue:6

    Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Pravastatin; Pyrroles; Sex Characteristics

2007
Effects of high-dose atorvastatin in patients > or =65 years of age with acute coronary syndrome (from the myocardial ischemia reduction with aggressive cholesterol lowering [MIRACL] study).
    The American journal of cardiology, 2007, Mar-01, Volume: 99, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Atorvastatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Retrospective Studies; Syndrome; Treatment Outcome

2007
[Effect of therapy with atorvastatin on parameters of postprandial lipemia and factors of inflammation in patients with ischemic heart disease].
    Kardiologiia, 2007, Volume: 47, Issue:2

    Topics: Adult; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Female; Fibrinogen; Heptanoic Acids; Humans; Hyperlipidemias; Inflammation; Lipids; Male; Myocardial Ischemia; Postprandial Period; Pyrroles; Treatment Outcome

2007
[Randomized FARVATER study. Part 2. Effect of atorvastatin on endothelial function, distensibility and stiffness of vascular wall].
    Kardiologiia, 2007, Volume: 47, Issue:2

    Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Blood Vessels; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hyperlipidemias; Lipids; Male; Middle Aged; Myocardial Ischemia; Pyrroles

2007
A 6 month randomized, double blind, placebo controlled, multi-center trial of high dose atorvastatin on myocardial perfusion abnormalities by positron emission tomography in coronary artery disease.
    American heart journal, 2008, Volume: 155, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Atorvastatin; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; Double-Blind Method; Heart; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Myocardial Ischemia; Positron-Emission Tomography; Prospective Studies; Pyrroles

2008
[Effect of atorvastatin therapy on the level of secretory phospholipase A2 group IIA and on the modification of low density lipoproteins in patients with ischemic heart disease].
    Kardiologiia, 2007, Volume: 47, Issue:4

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol; Group II Phospholipases A2; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lecithins; Lipoproteins, LDL; Lysophosphatidylcholines; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Treatment Outcome; Triglycerides

2007
Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease. Atorvastatin versus Revascularization Treatment Investigators.
    The New England journal of medicine, 1999, Jul-08, Volume: 341, Issue:2

    Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Coronary Disease; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Quality of Life; Risk; Treatment Outcome

1999
[Significance of the follow-up of patients with ischemic cardiopathy in the treatment with atorvastatin as secondary prevention. Pilot study].
    Anales de medicina interna (Madrid, Spain : 1984), 2002, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Female; Follow-Up Studies; Heptanoic Acids; Humans; Male; Middle Aged; Myocardial Ischemia; Pilot Projects; Prospective Studies; Pyrroles

2002
Comparison of effect of intensive lipid lowering with atorvastatin to less intensive lowering with lovastatin on C-reactive protein in patients with stable angina pectoris and inducible myocardial ischemia.
    The American journal of cardiology, 2002, May-15, Volume: 89, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angina Pectoris; Atorvastatin; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Follow-Up Studies; Heptanoic Acids; Humans; Hypolipidemic Agents; Lovastatin; Middle Aged; Myocardial Ischemia; Pyrroles; Time Factors; Treatment Outcome; Triglycerides

2002

Other Studies

39 other study(ies) available for atorvastatin and Myocardial Ischemia

ArticleYear
Effects of Atorvastatin on Transient Sodium Currents in Rat Normal, Simulated Ischemia, and Reperfusion Ventricular Myocytes.
    Pharmacology, 2020, Volume: 105, Issue:5-6

    Topics: Animals; Anti-Arrhythmia Agents; Atorvastatin; Female; Heart Ventricles; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Random Allocation; Rats; Rats, Wistar; Sodium; Sodium Channels; Time Factors

2020
Molecular pathways involved in the cardioprotective effects of intravenous statin administration during ischemia.
    Basic research in cardiology, 2019, 11-28, Volume: 115, Issue:1

    Topics: Administration, Intravenous; AMP-Activated Protein Kinases; Animals; Apoptosis; Atorvastatin; Cellular Senescence; Drug Evaluation, Preclinical; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Myocardial Ischemia; Neutrophil Infiltration; Random Allocation; Rats; Regulatory-Associated Protein of mTOR; rhoA GTP-Binding Protein; Simvastatin; Swine; TOR Serine-Threonine Kinases

2019
Pharmacology of atorvastatin on myocardial ischemia-reperfusion in rats and drug effect analysis.
    Pakistan journal of pharmaceutical sciences, 2019, Volume: 32, Issue:5(Special)

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Female; Male; Myocardial Infarction; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2019
Atorvastatin attenuates intermittent hypoxia-induced myocardial oxidative stress in a mouse obstructive sleep apnea model.
    Aging, 2021, 07-21, Volume: 13, Issue:14

    Topics: Animals; Apoptosis; Atorvastatin; Disease Models, Animal; Heart; Hypoxia; Male; Mice; Mice, Inbred C57BL; Myocardial Ischemia; NF-E2-Related Factor 2; Oxidative Stress; Sleep Apnea, Obstructive

2021
Atorvastatin Attenuates Metabolic Remodeling in Ischemic Myocardium through the Downregulation of UCP2 Expression.
    International journal of medical sciences, 2018, Volume: 15, Issue:5

    Topics: Angiotensin II; Animals; Atorvastatin; Coronary Vessels; Disease Models, Animal; Energy Metabolism; Gene Expression Regulation; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Rats; Uncoupling Protein 2

2018
Intravenous Statin Administration During Ischemia Exerts Cardioprotective Effects.
    Journal of the American College of Cardiology, 2019, 07-23, Volume: 74, Issue:3

    Topics: Animals; Atorvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Intravenous; Myocardial Ischemia; Random Allocation; Swine

2019
Differential effects of atorvastatin on autophagy in ischemic and nonischemic myocardium in Ossabaw swine with metabolic syndrome.
    The Journal of thoracic and cardiovascular surgery, 2014, Volume: 148, Issue:6

    Topics: Animals; Atorvastatin; Autophagy; Biomarkers; Cholesterol, Dietary; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metabolic Syndrome; Myocardial Ischemia; Myocardium; Pyrroles; Signal Transduction; Swine

2014
Atorvastatin regulates apoptosis in chronically ischemic myocardium.
    Journal of cardiac surgery, 2015, Volume: 30, Issue:2

    Topics: Animals; Apoptosis; Atorvastatin; bcl-2-Associated X Protein; Caspase 3; Chronic Disease; Disease Models, Animal; Gene Expression Regulation, Developmental; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MAP Kinase Signaling System; Metabolic Syndrome; Myocardial Ischemia; Myocardium; Neovascularization, Pathologic; Pyrroles; Swine; Swine, Miniature

2015
The Effects and Mechanism of Atorvastatin on Pulmonary Hypertension Due to Left Heart Disease.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Animals; Aorta; Apoptosis; Arterioles; Atorvastatin; Cell Proliferation; Heart Diseases; Heart Failure; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Inflammation; Lung; Macrophages; Male; Myocardial Ischemia; Neutrophils; Rats; Rats, Sprague-Dawley

2016
Cardioprotective effect of atorvastatin alone or in combination with remote ischemic preconditioning on the biochemical changes induced by ischemic/reperfusion injury in a mutual prospective study with a clinical and experimental animal arm.
    International journal of cardiology, 2016, Nov-01, Volume: 222

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Atorvastatin; Biomarkers; C-Reactive Protein; Cytokines; Disease Models, Animal; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Preconditioning; Male; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Prospective Studies; Rabbits; Treatment Outcome; Young Adult

2016
[Pleotropic Effects of Atorvastatin in Patients With Chronic Ischemic Heart Disease].
    Kardiologiia, 2016, Volume: 56, Issue:5

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Middle Aged; Myocardial Ischemia; Pyrroles

2016
[The efficasy of atorvastatin in the case of paroxismal atrial fibrillation in patients with ischemic heart disease].
    Georgian medical news, 2010, Issue:180

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atorvastatin; Atrial Fibrillation; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Treatment Outcome

2010
Atorvastatin pretreatment diminishes the levels of myocardial ischemia markers early after CABG operation: an observational study.
    Journal of cardiothoracic surgery, 2010, Aug-13, Volume: 5

    Topics: Aged; Atorvastatin; Biomarkers; Coronary Artery Bypass; Creatine Kinase, MB Form; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Troponin I

2010
[Individual pharmacotherapy safety in the assessment of cytochrome P-450 3A4 (CYP3A4) isoenzyme activity].
    Klinicheskaia meditsina, 2010, Volume: 88, Issue:2

    Topics: Atorvastatin; Clinical Trials as Topic; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Pharmacokinetics; Platelet Aggregation Inhibitors; Precision Medicine; Pyrroles; Ticlopidine

2010
[Association of a polymorphic marker Trp719Arg of KIF6 gene with effects of atorvastatin and simvastatin in patients with early ischemic heart disease].
    Kardiologiia, 2011, Volume: 51, Issue:9

    Topics: Age of Onset; Apolipoprotein A-I; Atorvastatin; C-Reactive Protein; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hypolipidemic Agents; Kinesins; Male; Middle Aged; Myocardial Ischemia; Pharmacogenetics; Polymorphism, Genetic; Pyrroles; Simvastatin; Treatment Outcome

2011
Phospholipase A2 enzymes, high-dose atorvastatin, and prediction of ischemic events after acute coronary syndromes.
    Circulation, 2012, Feb-14, Volume: 125, Issue:6

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acute Coronary Syndrome; Aged; Atherosclerosis; Atorvastatin; Biomarkers; C-Reactive Protein; Double-Blind Method; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Lipoproteins; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Ischemia; Oxidation-Reduction; Phospholipases A2, Secretory; Pyrroles; Randomized Controlled Trials as Topic; Retrospective Studies; Risk; Risk Factors; Survival Analysis

2012
[Protective effect of atrovastatin against myocardial ischemia-reperfusion injury and on liver and kidney functions in aged rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:3

    Topics: Aging; Animals; Atorvastatin; Female; Heptanoic Acids; Kidney; Liver; Male; Multiple Organ Failure; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Wistar

2012
What price atorvastatin?
    Drug and therapeutics bulletin, 2012, Volume: 50, Issue:7

    Topics: Anticholesteremic Agents; Atorvastatin; Drug Costs; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Pyrroles; Risk Factors

2012
[Painless myocardial ischemia in patient with extensive constrictive atherosclerosis of coronary arteries].
    Kardiologiia, 2012, Volume: 52, Issue:2

    Topics: Angioplasty; Anticholesteremic Agents; Asymptomatic Diseases; Atorvastatin; Cardiovascular Agents; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Drug-Eluting Stents; Echocardiography; Electrophysiologic Techniques, Cardiac; Exercise Test; Heptanoic Acids; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Severity of Illness Index; Treatment Outcome

2012
Atorvastatin increases oxidative stress and modulates angiogenesis in Ossabaw swine with the metabolic syndrome.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 144, Issue:6

    Topics: Angiogenesis Inducing Agents; Angiogenic Proteins; Animals; Atorvastatin; Biomarkers; Collateral Circulation; Coronary Circulation; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Male; Metabolic Syndrome; Microvessels; Myocardial Ischemia; Myocardial Perfusion Imaging; Myocardium; Neovascularization, Physiologic; Oxidative Stress; Pyrroles; Signal Transduction; Swine; Swine, Miniature; Vasodilation; Vasodilator Agents

2012
Aggressive lipid-lowering in stable patients with coronary artery disease.
    The Journal of family practice, 1999, Volume: 48, Issue:10

    Topics: Angioplasty; Atorvastatin; Coronary Disease; Heptanoic Acids; Humans; Hyperlipidemias; Male; Multicenter Studies as Topic; Myocardial Ischemia; Pyrroles; Quality of Life; Randomized Controlled Trials as Topic

1999
Atorvastatin, administered at the onset of reperfusion, and independent of lipid lowering, protects the myocardium by up-regulating a pro-survival pathway.
    Journal of the American College of Cardiology, 2003, Feb-05, Volume: 41, Issue:3

    Topics: Animals; Atorvastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardial Ischemia; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Pyrroles; Reperfusion; Signal Transduction; Time Factors; Up-Regulation

2003
Pretreatment with statins enhances myocardial protection during coronary revascularization.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 125, Issue:5

    Topics: Animals; Atorvastatin; Cardiopulmonary Bypass; Disease Models, Animal; Electric Countershock; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Myocardial Ischemia; Myocardial Revascularization; Premedication; Pyrroles; Random Allocation; Swine

2003
[Comparative study of lipid lowering effect and influence on platelet aggregation of atorvastatin and simvastatin in patients ischemic heart disease with type II diabetes and combined hyperlipidemia].
    Kardiologiia, 2003, Volume: 43, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Diabetes Mellitus, Type 2; Heptanoic Acids; Humans; Hyperlipidemias; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation; Pyrroles; Simvastatin

2003
Pharmacoeconomic evaluation of the effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes.
    The American journal of cardiology, 2003, Nov-01, Volume: 92, Issue:9

    Topics: Acute Disease; Angina, Unstable; Atorvastatin; Cost-Benefit Analysis; Economics, Pharmaceutical; Health Care Costs; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Infarction; Myocardial Ischemia; Pyrroles; Secondary Prevention; Syndrome

2003
High-dose statins in acute coronary syndromes.
    JAMA, 2005, Jan-05, Volume: 293, Issue:1

    Topics: Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Myocardial Ischemia; Pyrroles; Risk; Simvastatin

2005
Effect of aggressive versus moderate lipid-lowering therapy on myocardial ischemia: the rationale, design, and baseline characteristics of the Study Assessing Goals in the Elderly (SAGE).
    American heart journal, 2004, Volume: 148, Issue:6

    Topics: Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Coronary Disease; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Ischemia; Pravastatin; Prospective Studies; Pyrroles; Randomized Controlled Trials as Topic; Research Design

2004
A tale of two trials: a comparison of the post-acute coronary syndrome lipid-lowering trials A to Z and PROVE IT-TIMI 22.
    Circulation, 2006, Mar-21, Volume: 113, Issue:11

    Topics: Aged; Angina, Unstable; Atorvastatin; C-Reactive Protein; Cardiovascular Diseases; Case Management; Chemical and Drug Induced Liver Injury; Comorbidity; Confounding Factors, Epidemiologic; Dose-Response Relationship, Drug; Endpoint Determination; Female; Heptanoic Acids; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Tables; Lipids; Male; Middle Aged; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Myocardial Revascularization; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Research Design; Risk; Risk Factors; Simvastatin; Stroke; Tirofiban; Treatment Outcome; Tyrosine

2006
Direct comparison of the A to Z and PROVE IT trials: a second chance to gain a first impression.
    Circulation, 2006, Mar-21, Volume: 113, Issue:11

    Topics: Africa; Angioplasty, Balloon, Coronary; Asia; Atorvastatin; Australia; Canada; Case Management; Cholesterol, LDL; Confounding Factors, Epidemiologic; Dose-Response Relationship, Drug; Endpoint Determination; Europe; Heptanoic Acids; Humans; Multicenter Studies as Topic; Myocardial Ischemia; New Zealand; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Research Design; Risk; Simvastatin; South America; Stents; Tirofiban; Treatment Outcome; Tyrosine; United States

2006
High-dose atorvastatin improves hypercholesterolemic coronary endothelial dysfunction without improving the angiogenic response.
    Circulation, 2006, Jul-04, Volume: 114, Issue:1 Suppl

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Angiostatins; Animals; Apoptosis; Apoptosis Inducing Factor; Arterioles; Atorvastatin; Caspase 3; Caspases; Cholesterol; Coronary Circulation; Coronary Vessels; Drug Evaluation, Preclinical; Endostatins; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Matrix Metalloproteinase 9; Myocardial Ischemia; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Receptor, TIE-2; Swine; Swine, Miniature; Vascular Endothelial Growth Factor A; Vasodilation

2006
Aspirin before reperfusion blunts the infarct size limiting effect of atorvastatin.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Atorvastatin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Membrane Proteins; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats; Rats, Sprague-Dawley

2007
Statin therapy and the elderly: SAGE advice?
    Circulation, 2007, Feb-13, Volume: 115, Issue:6

    Topics: Age Factors; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cholesterol; Coronary Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Ischemia; Pravastatin; Pyrroles

2007
Statin wars following coronary revascularization - evidence-based clinical practice?
    The Canadian journal of cardiology, 2007, Mar-15, Volume: 23, Issue:4

    Topics: Atorvastatin; Canada; Drug Industry; Evidence-Based Medicine; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Myocardial Revascularization; Pyrroles

2007
Reducing myocardial injury by minimizing imbalance between oxygen supply and demand.
    Anesthesiology, 2007, Volume: 107, Issue:1

    Topics: Anesthesiology; Animals; Atorvastatin; Blood Pressure; Cardiovascular Agents; Coronary Disease; Dogs; Heart Diseases; Heart Rate; Heptanoic Acids; History, 20th Century; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Myocardial Revascularization; Necrosis; Oxygen; Pyrroles

2007
Atorvastatin impairs the myocardial angiogenic response to chronic ischemia in normocholesterolemic swine.
    The Journal of thoracic and cardiovascular surgery, 2008, Volume: 135, Issue:1

    Topics: Animals; Atorvastatin; Cholesterol; Collateral Circulation; Coronary Circulation; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Male; Microcirculation; Myocardial Ischemia; Neovascularization, Physiologic; Pyrroles; Swine

2008
Rationale and design of the Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study that evaluates atorvastatin in unstable angina pectoris and in non-Q-wave acute myocardial infarction.
    The American journal of cardiology, 1998, Mar-01, Volume: 81, Issue:5

    Topics: Angina, Unstable; Anticholesteremic Agents; Atorvastatin; Heptanoic Acids; Humans; Multicenter Studies as Topic; Myocardial Infarction; Myocardial Ischemia; Pyrroles; Randomized Controlled Trials as Topic; Recurrence; Research Design; Treatment Outcome

1998
Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease.
    The New England journal of medicine, 1999, Dec-09, Volume: 341, Issue:24

    Topics: Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Atorvastatin; Coronary Disease; Heptanoic Acids; Humans; Hypercholesterolemia; Myocardial Ischemia; Pyrroles; Recurrence

1999
[Are all HMG-CoA reductase inhibitors protective against ischemic heart disease?].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1999, Volume: 114 Suppl 1

    Topics: Adenosine Triphosphate; Animals; Atorvastatin; Dogs; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Myocardial Contraction; Myocardial Ischemia; Myocardial Stunning; Myocardium; Pravastatin; Pyridines; Pyrroles; Simvastatin

1999
[Meeting report. "MIRACL" study of "Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering"].
    Revue medicale de Liege, 2000, Volume: 55, Issue:12

    Topics: Anticholesteremic Agents; Atorvastatin; Heptanoic Acids; Humans; Hypercholesterolemia; Myocardial Ischemia; Patient Selection; Pyrroles; Treatment Outcome

2000