Page last updated: 2024-08-24

atorvastatin and Infarction, Middle Cerebral Artery

atorvastatin has been researched along with Infarction, Middle Cerebral Artery in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (27.27)29.6817
2010's14 (63.64)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Betterton, RD; Davis, TP; Lochhead, JJ; Moreno-Rodriguez, VM; Ronaldson, PT; Stanton, JA; Williams, EI1
Salayandia, VM; Thompson, JF; Torbey, M; Yang, LY; Yang, Y1
Cheng, ZJ; Dai, TM; He, JL; Li, J; Shen, YY; Tu, JL1
Aras, Y; Bagci-Onder, T; Erdag, E; Genc, C; Izgi, N; Tahta, A1
Chao, HC; Chiang, CS; Kuo, CH; Lee, TH; Tang, SC; Yang, SY1
Deng, J; He, J; Hu, Z; Lei, Q; Liu, J; Lu, W; Song, T; Tao, X; Zhang, J; Zheng, L1
Deng, JG; Liu, J; Song, T; Tao, X1
Cheon, SY; Cho, KJ; Kim, GW1
Ahmad, MA; Akhtar, M; Mujeeb, M; Najmi, AK1
Khodagholi, F; Mehrpour, M; Naderi, N; Nasoohi, S; Simani, L1
Cardona-Gómez, GP; Guarin, CJ; Gutierrez-Vargas, J; Hernández, PA; Rodríguez-Perea, AL; Rojas, M1
Chen, TY; Kuo, YL; Lin, WC; Tan, TY1
Cui, L; Du, W; Li, M; Liu, L; Wang, L; Yang, R; Zhang, X1
Cardona-Gómez, GP; Céspedes-Rubio, A; Jurado, FW1
Abe, K; Deguchi, K; Deguchi, S; Ikeda, Y; Liu, N; Liu, W; Matsuura, T; Ohta, Y; Shang, J; Tian, F; Yamashita, T; Zhang, X1
Binning, MJ; Darkhabani, Z; Levy, EI; Mokin, M; Siddiqui, AH1
Du, Y; Ji, H; Li, L; Li, S; Liu, H; Zhang, X1
Abe, K; Deguchi, K; Hayashi, T; Nagano, I; Nagotani, S; Sato, K; Shoji, M; Zhang, W1
Appel, K; Fiebich, BL; Hüll, M; Kauppinen, RA; Kettunen, M; Koistinaho, J; Yrjänheikki, J1
Chen, J; Chopp, M; Ding, J; Kapke, A; Li, A; Lu, M; Roberts, C; Zacharek, A; Zhang, C1
Chopp, M; Hozeska-Solgot, A; Liu, XS; Zhang, L; Zhang, ZG1
Böhm, M; Dirnagl, U; Endres, M; Gertz, K; Huang, P; Laufs, U; Nickenig, G1

Other Studies

22 other study(ies) available for atorvastatin and Infarction, Middle Cerebral Artery

ArticleYear
Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke.
    Stroke, 2023, Volume: 54, Issue:11

    Topics: Animals; Atorvastatin; Brain Edema; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Neuroprotection; Neuroprotective Agents; Organic Anion Transporters; Rats; Rats, Sprague-Dawley; Stroke

2023
Treatment with Atorvastatin During Vascular Remodeling Promotes Pericyte-Mediated Blood-Brain Barrier Maturation Following Ischemic Stroke.
    Translational stroke research, 2021, Volume: 12, Issue:5

    Topics: Animals; Atorvastatin; Blood-Brain Barrier; Brain Ischemia; Humans; Infarction, Middle Cerebral Artery; Ischemic Stroke; Pericytes; Rats; Stroke; Vascular Remodeling

2021
Atorvastatin Pretreatment Attenuates Ischemic Brain Edema by Suppressing Aquaporin 4.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:11

    Topics: Animals; Aquaporin 4; Atorvastatin; Behavior, Animal; Body Water; Brain; Brain Edema; Disease Models, Animal; Down-Regulation; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats, Sprague-Dawley; Signal Transduction

2018
Assessment of the MRI and Behavioral Test Results in a Focal Cerebral Ischemia-Reperfusion Model in the Rat after Separate and Combined Use of Mouse-Derived Neural Progenitor Cells, Human-Derived Neural Progenitor Cells and Atorvastatin.
    Turkish neurosurgery, 2018, Volume: 28, Issue:4

    Topics: Animals; Atorvastatin; Behavior Rating Scale; Disease Models, Animal; Humans; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Mice; Neural Stem Cells; Rats; Recovery of Function; Reperfusion Injury; Stroke

2018
Sphingolipidomics Investigation of the Temporal Dynamics after Ischemic Brain Injury.
    Journal of proteome research, 2019, 09-06, Volume: 18, Issue:9

    Topics: Animals; Atorvastatin; Brain; Brain Injuries; Brain Ischemia; Ceramides; Chromatography, High Pressure Liquid; Disease Models, Animal; Humans; Infarction, Middle Cerebral Artery; Lipidomics; Lysophospholipids; Mice; Sphingolipids; Sphingosine; Stroke; Tandem Mass Spectrometry

2019
HspB8 expression in brain tissue after cerebral ischemic reperfusion and atorvastatin intervention in Sprague-Dawley rats.
    Neurological research, 2015, Volume: 37, Issue:3

    Topics: Animals; Apoptosis; Atorvastatin; Blotting, Western; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Heat-Shock Proteins; Heptanoic Acids; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Pyrroles; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Tetrazolium Salts

2015
Protection effect of atorvastatin in cerebral ischemia-reperfusion injury rats by blocking the mitochondrial permeability transition pore.
    Genetics and molecular research : GMR, 2014, Dec-18, Volume: 13, Issue:4

    Topics: Animals; Anticholesteremic Agents; Apoptosis; Atorvastatin; Brain Ischemia; Cytochromes c; Disease Models, Animal; Heptanoic Acids; Infarction, Middle Cerebral Artery; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Pyrroles; Rats, Sprague-Dawley; Reperfusion Injury

2014
Statins Promote Long-Term Recovery after Ischemic Stroke by Reconnecting Noradrenergic Neuronal Circuitry.
    Neural plasticity, 2015, Volume: 2015

    Topics: Animals; Atorvastatin; Behavior, Animal; Brain Ischemia; Cell Proliferation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Locus Coeruleus; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neurogenesis; Recovery of Function; Stroke; Sympathetic Nervous System

2015
Protective Effect of Guggulipid in High Fat Diet and Middle Cerebral Artery Occlusion (MCAO) Induced Ischemic Cerebral Injury in Rats.
    Drug research, 2016, Volume: 66, Issue:8

    Topics: Animals; Aspirin; Atorvastatin; Brain; Brain Ischemia; Catalase; Commiphora; Diet, High-Fat; Drug Therapy, Combination; Female; Glutathione; Hand Strength; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Locomotion; Male; Neuroprotective Agents; Phytotherapy; Plant Extracts; Plant Gums; Rats; Superoxide Dismutase

2016
Association of Long-Term Atorvastatin with Escalated Stroke-Induced Neuroinflammation in Rats.
    Journal of molecular neuroscience : MN, 2017, Volume: 61, Issue:1

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; bcl-2-Associated X Protein; Caspase 9; Infarction, Middle Cerebral Artery; Inflammation; Interleukin-6; Male; Neurons; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2017
Atorvastatin Modulates Regulatory T Cells and Attenuates Cerebral Damage in a Model of Transient Middle Cerebral Artery Occlusion in Rats.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2017, Volume: 12, Issue:1

    Topics: Animals; Atorvastatin; Brain; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Wistar; T-Lymphocytes, Regulatory

2017
Effect of lipid-lowering therapy on the progression of intracranial arterial stenosis.
    Journal of neurology, 2009, Volume: 256, Issue:2

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cerebral Arteries; Constriction, Pathologic; Disease Progression; Female; Heptanoic Acids; Humans; Hyperlipidemias; Infarction, Middle Cerebral Artery; Intracranial Arteriosclerosis; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Secondary Prevention; Sex Distribution; Stroke; Treatment Outcome; Vertebrobasilar Insufficiency

2009
Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15-LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability.
    Brain research, 2010, Apr-14, Volume: 1325

    Topics: Acute Disease; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Atorvastatin; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Capillary Permeability; Down-Regulation; Heptanoic Acids; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Phospholipases A2, Cytosolic; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Stroke; Time Factors

2010
p120 catenin/αN-catenin are molecular targets in the neuroprotection and neuronal plasticity mediated by atorvastatin after focal cerebral ischemia.
    Journal of neuroscience research, 2010, Volume: 88, Issue:16

    Topics: alpha Catenin; Analysis of Variance; Animals; Atorvastatin; Brain Ischemia; Catenins; Cell Adhesion Molecules; Cell Death; Cerebral Cortex; Delta Catenin; Gene Expression Regulation; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Longitudinal Studies; Male; Nerve Tissue Proteins; Neuronal Plasticity; Neuroprotective Agents; Protein Isoforms; Pyrroles; Rats; Rats, Wistar; Statistics, Nonparametric; Synapses

2010
Amlodipine and atorvastatin exert protective and additive effects via antiapoptotic and antiautophagic mechanisms after transient middle cerebral artery occlusion in Zucker metabolic syndrome rats.
    Journal of neuroscience research, 2011, Volume: 89, Issue:8

    Topics: Amlodipine; Animals; Antihypertensive Agents; Apoptosis; Atorvastatin; Autophagy; Brain; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Pyrroles; Rats; Rats, Zucker

2011
Small unruptured partially thrombosed aneurysms and stroke: report of three cases and review of the literature.
    Journal of neurointerventional surgery, 2012, Volume: 4, Issue:3

    Topics: Aspirin; Atorvastatin; Craniotomy; Echocardiography, Transesophageal; Fibrinolytic Agents; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Intracranial Aneurysm; Intracranial Embolism; Male; Middle Aged; Neurosurgical Procedures; Paresis; Pyrroles; Stroke; Tomography, X-Ray Computed; Ultrasonography, Doppler, Color

2012
Probucol and atorvastatin in combination protect rat brains in MCAO model: upregulating Peroxiredoxin2, Foxo3a and Nrf2 expression.
    Neuroscience letters, 2012, Feb-16, Volume: 509, Issue:2

    Topics: Animals; Atorvastatin; Body Fluids; Brain; Disease Models, Animal; Drug Therapy, Combination; Forkhead Box Protein O3; Forkhead Transcription Factors; Heptanoic Acids; Infarction, Middle Cerebral Artery; Male; NF-E2-Related Factor 2; Peroxiredoxins; Probucol; Pyrroles; Rats; Up-Regulation; Water

2012
Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress.
    Stroke, 2005, Volume: 36, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Atorvastatin; Blood Pressure; Body Weight; Deoxyguanosine; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Infarction, Middle Cerebral Artery; Lipids; Lysine; Oxidative Stress; Pyrroles; Quinolines; Rats; Rats, Inbred SHR; Simvastatin; Survival Analysis

2005
Long-term protective effect of atorvastatin in permanent focal cerebral ischemia.
    Brain research, 2005, Aug-09, Volume: 1052, Issue:2

    Topics: Animals; Atorvastatin; Behavior, Animal; Blood Circulation; Brain Infarction; Brain Ischemia; Dizocilpine Maleate; Heptanoic Acids; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Motor Activity; Neuroprotective Agents; Psychomotor Performance; Pyrroles; Rats; Rats, Long-Evans; Recovery of Function; Staining and Labeling; Time; Time Factors

2005
Vascular endothelial growth factor mediates atorvastatin-induced mammalian achaete-scute homologue-1 gene expression and neuronal differentiation after stroke in retired breeder rats.
    Neuroscience, 2006, Aug-25, Volume: 141, Issue:2

    Topics: Analysis of Variance; Animals; Antibodies; Atorvastatin; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Motor Activity; Neurons; Pyrroles; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tubulin; Vascular Endothelial Growth Factor A

2006
The PI3K/Akt pathway mediates the neuroprotective effect of atorvastatin in extending thrombolytic therapy after embolic stroke in the rat.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:11

    Topics: Animals; Atorvastatin; Biosynthetic Pathways; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Early Growth Response Protein 1; Fibrinolytic Agents; Heptanoic Acids; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Wistar; Tissue Plasminogen Activator; Vascular Endothelial Growth Factor A

2007
Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice.
    Stroke, 2000, Volume: 31, Issue:10

    Topics: Animals; Aorta; Atorvastatin; beta-Thromboglobulin; Blood Coagulation; Blood Platelets; Brain Ischemia; Cholesterol; Dose-Response Relationship, Drug; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infarction, Middle Cerebral Artery; Mice; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Activation; Platelet Factor 4; Pyrroles; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; RNA, Messenger; Up-Regulation

2000