Page last updated: 2024-08-24

atorvastatin and Hypertension, Pulmonary

atorvastatin has been researched along with Hypertension, Pulmonary in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (35.00)29.6817
2010's11 (55.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Cao, GQ; Liu, H; Liu, JY; Tang, MM; Zhang, XQ; Zhu, YT1
Gao, G; Lian, G; Lin, T; Luo, L; Wang, H; Wu, J; Xie, L1
Cai, X; Huang, X; Jiang, Z; Lin, Z; Wang, H; Xie, L1
Chen, P; Dai, L; Wu, S; Zhang, Y; Zhao, S1
Chen, ZC; Cheng, KL; Cheng, SY; Guo, YZ; Ou, MD; Wang, Q; Xue, JJ; Zeng, WJ; Zhang, YT1
Bardou, M; Dumas, M; Goirand, F; Guerard, P; Lirussi, F; Rakotoniaina, Z; Rochette, L2
Satoh, A; Satoh, M1
Maciocia, PM1
Ozturk, EI; Uma, S1
Fan, ZX; Gao, YF; Jing, ZC; Li, J; Li, L; Ma, D; Shi, DM; Wang, YW; Wu, BX; Zhu, XD1
Lin, P; Xie, H; Xie, L; Xu, C1
Dai, L; Wu, S1
DeFilippis, A; Eberlein, M; Girgis, RE; Iacono, A; Jones, S; Lechtzin, N; Reed, RM1
Cheng, XS; Gu, Q; He, JG; Liu, ZH; Ni, XH; Shan, GL; Wilkins, MR; Xiong, CM; Xue, F; Zeng, WJ; Zhao, L; Zhao, ZH1
Chen, D; Chen, F; Dong, L; Ge, J; Guan, L; Qian, J; Zhou, D1
Alves-Filho, JC; Cunha, FQ; Figueiredo-Lopes, L; Gerlach, RF; Semprini, MC; Souza-Costa, DC; Tanus-Santos, JE1
Almog, Y; Avnon, LS1
Christians, U; Kaisers, U; Laudi, S; McMurtry, IF; Mutlak, H; Schmitz, V; Steudel, W; Trump, S; Weimann, J; West, J1
Archer, SL; Bonnet, S; Haromy, A; McMurtry, MS; Michelakis, ED1

Reviews

1 review(s) available for atorvastatin and Hypertension, Pulmonary

ArticleYear
The pressure is rising.
    Critical care medicine, 2007, Volume: 35, Issue:1

    Topics: Animals; Atorvastatin; Critical Care; Disease Models, Animal; Drug Evaluation, Preclinical; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Pulmonary Embolism; Pyrroles; Rats

2007

Trials

1 trial(s) available for atorvastatin and Hypertension, Pulmonary

ArticleYear
Atorvastatin in pulmonary arterial hypertension (APATH) study.
    The European respiratory journal, 2012, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Double-Blind Method; Exercise Tolerance; Familial Primary Pulmonary Hypertension; Female; Hemodynamics; Heptanoic Acids; Humans; Hypertension, Pulmonary; Lung; Male; Middle Aged; Pyrroles; Treatment Outcome; Walking; Young Adult

2012

Other Studies

18 other study(ies) available for atorvastatin and Hypertension, Pulmonary

ArticleYear
Effect of atorvastatin on pulmonary hypertension rats through regulating notch signaling pathway.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:9

    Topics: Administration, Oral; Animals; Apoptosis; Atorvastatin; Disease Models, Animal; Hypertension, Pulmonary; Male; Rats; Rats, Sprague-Dawley; Receptor, Notch1; Signal Transduction

2020
Influence of atorvastatin on metabolic pattern of rats with pulmonary hypertension.
    Aging, 2021, 04-22, Volume: 13, Issue:8

    Topics: Animals; Arterial Pressure; Atorvastatin; Disease Models, Animal; Fatty Acids; Glycolysis; Humans; Hypertension, Pulmonary; Lung; Male; Metabolomics; Monocrotaline; Oxidation-Reduction; Pulmonary Artery; Rats; Vascular Remodeling

2021
Preventive treatment with atorvastatin ameliorates endothelial dysfunction of small pulmonary arteries in monocrotaline-induced pulmonary hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:6

    Topics: Animals; Atorvastatin; Endothelium; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Artery; Pulmonary Wedge Pressure; Random Allocation; Rats; Rats, Sprague-Dawley; Vasodilation

2017
Atorvastatin attenuates involvement of RhoA/Rho-kinase pathway and NF-κB activation in hypoxic pulmonary hypertensive rats.
    Chinese medical journal, 2014, Volume: 127, Issue:5

    Topics: Animals; Atorvastatin; Blotting, Western; Heptanoic Acids; Hypertension, Pulmonary; Hypoxia; Male; NF-kappa B; Pyrroles; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

2014
The Effects and Mechanism of Atorvastatin on Pulmonary Hypertension Due to Left Heart Disease.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Animals; Aorta; Apoptosis; Arterioles; Atorvastatin; Cell Proliferation; Heart Diseases; Heart Failure; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Inflammation; Lung; Macrophages; Male; Myocardial Ischemia; Neutrophils; Rats; Rats, Sprague-Dawley

2016
Celecoxib but not the combination of celecoxib+atorvastatin prevents the development of monocrotaline-induced pulmonary hypertension in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:3

    Topics: Acetylcholine; Animals; Atorvastatin; Blotting, Western; Body Weight; Caspase 3; Celecoxib; Cyclooxygenase Inhibitors; Disease Progression; Drug Combinations; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Nitric Oxide Synthase Type III; Pulmonary Artery; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfonamides; Survival Analysis; Vasodilator Agents

2008
3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2009, Feb-04, Volume: 11, Issue:2

    Topics: Animals; Atorvastatin; Disease Models, Animal; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Male; Monocrotaline; Phosphodiesterase Inhibitors; Pravastatin; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Simvastatin

2009
Inflammatory signaling in pulmonary arterial hypertension: the controversial role of CRP, and the search for new therapies.
    Cardiovascular therapeutics, 2010,Spring, Volume: 28, Issue:1

    Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Atorvastatin; C-Reactive Protein; Chemokine CCL2; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Inflammation Mediators; Interleukin-6; Muscle, Smooth, Vascular; NF-kappa B; Pulmonary Artery; Pyrroles

2010
Effects of atorvastatin and L-arginine treatments on electrical field stimulation-mediated relaxations in pulmonary arterial rings of monocrotaline-induced pulmonary hypertensive rats.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:5

    Topics: Animals; Arginine; Atorvastatin; Electric Stimulation; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; In Vitro Techniques; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Vasodilation

2010
The effects of atorvastatin on pulmonary arterial hypertension and expression of p38, p27, and Jab1 in rats.
    International journal of molecular medicine, 2010, Volume: 26, Issue:4

    Topics: Animals; Atorvastatin; COP9 Signalosome Complex; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Intracellular Signaling Peptides and Proteins; Male; Monocrotaline; p38 Mitogen-Activated Protein Kinases; Pneumonectomy; Proliferating Cell Nuclear Antigen; Proteins; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar

2010
Effects of atorvastatin and losartan on monocrotaline-induced pulmonary artery remodeling in rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2010, Volume: 32, Issue:8

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Atorvastatin; Base Sequence; Calcium Channels, L-Type; Disease Models, Animal; DNA Primers; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Inositol 1,4,5-Trisphosphate Receptors; Losartan; Male; Monocrotaline; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases

2010
[Atorvastatin attenuates hypoxic pulmonary hypertension in rats by inhibiting RhoA/Rho kinase pathway].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011, Volume: 36, Issue:1

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Hemodynamics; Heptanoic Acids; Hypertension, Pulmonary; Hypoxia; Male; Pulmonary Artery; Pyrroles; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Ventricular Remodeling

2011
Statin therapy is associated with decreased pulmonary vascular pressures in severe COPD.
    COPD, 2011, Volume: 8, Issue:2

    Topics: Aged; Atorvastatin; Cross-Sectional Studies; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Pulmonary Wedge Pressure; Pyrroles; Regression Analysis; Simvastatin

2011
Atorvastatin prevents dehydromonocrotaline-induced pulmonary hypertension in beagles.
    Experimental lung research, 2012, Volume: 38, Issue:7

    Topics: Alkylating Agents; Animals; Atorvastatin; Cell Proliferation; Cytokines; Dogs; Endothelium, Vascular; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Pyrroles

2012
The protective effect of HMG-CoA reductase inhibitors against monocrotaline-induced pulmonary hypertension in the rat might not be a class effect: comparison of pravastatin and atorvastatin.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 374, Issue:3

    Topics: Acetylcholine; Animals; Apoptosis; Atorvastatin; Caspase 3; Endothelial Cells; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Nitroprusside; Pravastatin; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Ventricular Pressure

2006
Protective effects of atorvastatin in rat models of acute pulmonary embolism: involvement of matrix metalloproteinase-9.
    Critical care medicine, 2007, Volume: 35, Issue:1

    Topics: Acute Disease; Analysis of Variance; Animals; Atorvastatin; Disease Models, Animal; Drug Evaluation, Preclinical; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Injections, Intravenous; Luminescence; Lung; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microspheres; Nitrates; Nitrites; Proportional Hazards Models; Pulmonary Embolism; Pulmonary Wedge Pressure; Pyrroles; Random Allocation; Rats; Rats, Wistar; Survival Rate

2007
Serotonin transporter protein in pulmonary hypertensive rats treated with atorvastatin.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:3

    Topics: Actins; Animals; Anticholesteremic Agents; Atorvastatin; Blood Pressure; Blotting, Western; Dose-Response Relationship, Drug; Echocardiography; Gene Expression Regulation; Heart Ventricles; Heptanoic Acids; Hypertension, Pulmonary; Immunohistochemistry; Male; Muscle, Smooth; Organ Size; Polymerase Chain Reaction; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin Plasma Membrane Transport Proteins; Systole

2007
Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Atorvastatin; Blood Pressure; Disease Progression; Dose-Response Relationship, Drug; Drug Synergism; Echocardiography; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Male; Monocrotaline; Phosphorylation; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Simvastatin; Sirolimus

2007