Page last updated: 2024-08-24

atorvastatin and Fatty Liver, Nonalcoholic

atorvastatin has been researched along with Fatty Liver, Nonalcoholic in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's32 (74.42)24.3611
2020's11 (25.58)2.80

Authors

AuthorsStudies
Mukhamejanova, Z; Pang, J; Tong, Y; Wen, T; Xiang, Q; Xu, F; Zhu, W1
Baumert, TF; Chung, RT; Corey, KE; Hoshida, Y; Kim, MH; Kim, MY; Lee, Y; Qian, T; Sadreyev, RI; Salloum, S; Shroff, SG; Wong, LP; Xu, M1
Bahreini, E; Barzin Tond, S; Fadaei, R; Fallah, S; Farahmandian, N; Karima, S; Koushki, M; Nourbakhsh, M; Rezaei, A; Yarahmadi, S1
Augusto, CT; de la Paz Scribano Parada, M; Del Carmen Baez, M; Fonseca, I; Rossi, MM; Signorini, F1
Caspers, MPM; Giera, M; Inia, JA; Jukema, JW; Menke, AL; Morrison, MC; Pieterman, EJ; Princen, HMG; Stokman, G; van den Hoek, AM; Verschuren, L1
Chen, WM; Chiang, MF; Lee, MC; Lo, HC; Soong, RS; Wu, MS; Wu, SY1
Cohen, DE; Freilich, B; Fuchs, M; Hellstern, PA; Kohli, A; Lawitz, EJ; MacConell, L; Owens-Grillo, J; Pockros, PJ; Schiff, E; Shapiro, D; Shringarpure, R; Van Biene, C1
Ipsen, DH; Klaebel, JH; Lykkesfeldt, J; Rakipovski, G; Schou-Pedersen, AMV; Skat-Rørdam, J; Skjødt, M; Tveden-Nyborg, P1
Abbasi, A; Farhad, N; Zarei, L1
Chan, AWH; Chu, ES; Coker, OO; Fu, K; Lau, HCH; Sung, JJY; Wang, YX; Wei, H; Yang, X; Yu, J; Zhang, X1
Athyros, VG; Doumas, M; Giouleme, O; Imprialos, K; Karagiannis, A; Koumaras, C; Perdikakis, E; Psallas, M; Sfikas, G1
Augustin, S; Barberá, A; Bravo, M; Estrella, F; Genescà, J; Gil, M; Hide, D; Martell, M; Raurell, I; Salcedo, MT1
Faistova, H; Faradonbeh, FA; Hroch, M; Hyspler, R; Igreja Sa, IC; Lastuvkova, H; Micuda, S; Mokry, J; Nachtigal, P; Nova, Z; Pavek, P; Schreiberova, J; Stefela, A1
Ahmed, S; Jamil, S; Khan, RA1
Athyros, VG; Katsiki, N; Mikhailidis, DP1
Athyros, VG; Giouleme, O; Grammatikos, N; Katsoula, A; Paschos, P; Tsimperidis, A1
Gao, H; Hu, Y; Li, X; Tian, R; Wang, Y; Williams, BR; Xu, P; Yan, F; Ying, L; Zhao, Y1
Cao, K; Feng, X; Gao, X; Nan, Y; Ren, B; Sun, C; Ye, J; Yu, M; Yuan, Y; Zhao, Y1
Chen, Y; Duan, Y; Han, J; Hu, W; Li, L; Li, X; Liu, L; Liu, M; Liu, Y; Miao, QR; Sun, L; Yang, X; Yu, M; Zhang, W; Zhang, X; Zhu, Y1
Farrell, GC; Gan, LT; Haigh, WG; Ioannou, G; Larter, CZ; Teoh, NC; Van Rooyen, DM; Yeh, MM1
Athyros, VG; Karagiannis, A; Katsiki, N; Mikhailidis, DP1
Droog, S; Havekes, LM; Maas, AC; Offerman, EH; Pieterman, EJ; Princen, HM; van den Hoek, AM; van den Hoogen, RM; van der Hoorn, JW; van Nieuwkoop, A1
Aramin, H; Eslami, L; Malekzadeh, R; Merat, S; Nasseri-Moghaddam, S1
Farrell, GC; Haigh, WG; Ioannou, GN; Savard, C; Teoh, NC; Van Rooyen, DM; Yeh, MM1
Dubrovins'ka, TV; Skrypnyk, IM1
Abd Elmaaboud, MA; Albarraq, AA; Kabel, AM1
Eguchi, Y; Fujita, K; Honda, Y; Hyogo, H; Imajo, K; Kessoku, T; Kirikoshi, H; Mawatari, H; Nakajima, A; Nozaki, Y; Ogawa, Y; Ono, M; Saito, S; Sumida, Y; Taguri, M; Tomeno, W; Wada, K; Yoneda, M1
Ajamieh, H; Chu, E; Farrell, GC; Lam, W; McCuskey, RS; Teoh, NC; Wong, HJ; Yu, J1
Adánez, G; Ayala, I; Castells, MT; García-Pérez, B; Martín, A; Sánchez-Polo, MT1
Hemming, K; Jafari, E; Khoshnia, M; Malekzadeh, R; Marshall, T; Merat, S; Nateghi, A; Poustchi, H; Radmard, AR; Shiravi Khuzani, A1
Klyarytskaya, IL; Maksymova, EV; Stilidi, EI1
Fung, KP; Koon, CM; Lau, CB; Lau, CP; Leung, PC; Liu, CL; Ng, CF; Pang, KY; Wat, E; Wong, CW; Zhang, C; Zhang, X1
Ahmadi, N; Budoff, MJ; Foster, T; Gordon, C; Guerci, AD; Saab, S1
Alegret, M; Ađalsteisson, GS; Laguna, JC; Merlos, M; Rebollo, A; Roglans, N; Vilà, L1
Allard, JP; Arendt, BM1
Amaral, C; Cipriano, A; Crisóstomo, J; Louro, T; Matafome, P; Monteiro, P; Nunes, E; Rodrigues, L; Seiça, R1
Ji, G; Jiang, Z; Leng, L; Liu, P; Zhao, X1
Hassanian, MA; Samy, W1
Chayama, K; Hyogo, H; Ishitobi, T; Kimura, Y; Maeda, S; Yamagishi, S1
Ajamieh, H; Chen, J; Chu, E; Farrell, G; Teoh, N; Wong, HJ; Yu, J1
Lonardo, A; Loria, P1
Gracia-Sancho, J1

Reviews

2 review(s) available for atorvastatin and Fatty Liver, Nonalcoholic

ArticleYear
Can Serum Uric Acid Lowering Therapy Contribute to the Prevention or Treatment of Nonalcoholic Fatty Liver Disease?
    Current vascular pharmacology, 2018, Volume: 16, Issue:3

    Topics: Allopurinol; Atorvastatin; Biomarkers; Gout Suppressants; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperuricemia; Non-alcoholic Fatty Liver Disease; Prevalence; Risk Factors; Treatment Outcome; Uric Acid

2018
Statins for non-alcoholic fatty liver disease and non-alcoholic steatohepatitis.
    The Cochrane database of systematic reviews, 2013, Dec-27, Issue:12

    Topics: Alanine Transaminase; Atorvastatin; Fatty Liver; Fenofibrate; gamma-Glutamyltransferase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Non-alcoholic Fatty Liver Disease; Pyrroles; Simvastatin

2013

Trials

9 trial(s) available for atorvastatin and Fatty Liver, Nonalcoholic

ArticleYear
CONTROL: A randomized phase 2 study of obeticholic acid and atorvastatin on lipoproteins in nonalcoholic steatohepatitis patients.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:11

    Topics: Adult; Aged; Atorvastatin; Bile Acids and Salts; Chenodeoxycholic Acid; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Treatment Outcome; United States

2019
Prevalence, Diagnosis, and Treatment with 3 Different Statins of Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis in Military Personnel. Do Genetics Play a Role?
    Current vascular pharmacology, 2021, Volume: 19, Issue:5

    Topics: Atorvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Military Personnel; Non-alcoholic Fatty Liver Disease; Prevalence; Rosuvastatin Calcium

2021
[Optimization of long-term hypolipidemia treatment of patients with myocardial infarction in combination with non-alcoholic steatohepatitis].
    Georgian medical news, 2014, Issue:229

    Topics: Atorvastatin; Bilirubin; Fluorobenzenes; Heptanoic Acids; Humans; Hypolipidemic Agents; Lipids; Liver; Middle Aged; Myocardial Infarction; Non-alcoholic Fatty Liver Disease; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Transaminases; Triglycerides; Ursodeoxycholic Acid

2014
LDL-migration index (LDL-MI), an indicator of small dense low-density lipoprotein (sdLDL), is higher in non-alcoholic steatohepatitis than in non-alcoholic fatty liver: a multicenter cross-sectional study.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Adult; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Azetidines; Cross-Sectional Studies; Ezetimibe; Female; Heptanoic Acids; Humans; Lipoproteins, LDL; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Pyrroles; Risk Factors

2014
PolyPill for Prevention of Cardiovascular Disease in an Urban Iranian Population with Special Focus on Nonalcoholic Steatohepatitis: A Pragmatic Randomized Controlled Trial within a Cohort (PolyIran - Liver) - Study Protocol.
    Archives of Iranian medicine, 2015, Volume: 18, Issue:8

    Topics: Angiotensin II Type 1 Receptor Blockers; Aspirin; Atorvastatin; Cardiovascular Diseases; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iran; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Platelet Aggregation Inhibitors; Urban Population; Valsartan

2015
[COMPARISON OF DIFFERENT TREATMENT REGIMENS IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2015, Issue:7

    Topics: Adult; Aged; Atorvastatin; Female; Humans; Interleukin-6; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid; Vitamin E

2015
Atorvastatin and antioxidants for the treatment of nonalcoholic fatty liver disease: the St Francis Heart Study randomized clinical trial.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:1

    Topics: Administration, Oral; Aged; Analysis of Variance; Antioxidants; Ascorbic Acid; Atorvastatin; California; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fatty Liver; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Multivariate Analysis; Non-alcoholic Fatty Liver Disease; Pyrroles; Risk Assessment; Severity of Illness Index; Tomography, X-Ray Computed; Treatment Outcome; Vitamin D

2011
Effect of atorvastatin, vitamin E and C on nonalcoholic fatty liver disease: is the combination required?
    The American journal of gastroenterology, 2011, Volume: 106, Issue:1

    Topics: Antioxidants; Ascorbic Acid; Atorvastatin; Confidence Intervals; Drug Therapy, Combination; Fatty Liver; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Non-alcoholic Fatty Liver Disease; Odds Ratio; Pyrroles; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Tomography, X-Ray Computed; Treatment Outcome; Vitamin A

2011
Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin.
    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology, 2011, Volume: 12, Issue:2

    Topics: Adult; Alanine Transaminase; Anticholesteremic Agents; Aryldialkylphosphatase; Aspartate Aminotransferases; Atorvastatin; Cholesterol; Cross-Sectional Studies; Disease Progression; Fatty Liver; Female; Glutathione Peroxidase; Hepatitis; Heptanoic Acids; Humans; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Pyrroles; Risk Factors; Triglycerides

2011

Other Studies

32 other study(ies) available for atorvastatin and Fatty Liver, Nonalcoholic

ArticleYear
Xyloketal B Reverses Nutritional Hepatic Steatosis, Steatohepatitis, and Liver Fibrosis through Activation of the PPARα/PGC1α Signaling Pathway.
    Journal of natural products, 2022, 07-22, Volume: 85, Issue:7

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Proteomics; Pyrans; Signal Transduction

2022
Atorvastatin favorably modulates a clinical hepatocellular carcinoma risk gene signature.
    Hepatology communications, 2022, Volume: 6, Issue:9

    Topics: Atorvastatin; Carcinoma, Hepatocellular; Hepatitis C; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Proto-Oncogene Proteins c-akt

2022
Therapeutic Potential of Resveratrol and Atorvastatin Following High-Fat Diet Uptake-Induced Nonalcoholic Fatty Liver Disease by Targeting Genes Involved in Cholesterol Metabolism and miR33.
    DNA and cell biology, 2023, Volume: 42, Issue:2

    Topics: Animals; Atorvastatin; ATP Binding Cassette Transporter 1; Cholesterol; Diet, High-Fat; Lipoproteins, LDL; Liver X Receptors; Mice; MicroRNAs; Non-alcoholic Fatty Liver Disease; Resveratrol

2023
Pharmacological Action of Atorvastatin and Metformin on Non-alcoholic Fatty Liver Disease on an Experimental Model of Metabolic Syndrome.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2023, Volume: 21, Issue:3

    Topics: Animals; Atorvastatin; Liver; Male; Metabolic Syndrome; Metformin; Models, Theoretical; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Superoxide Dismutase

2023
Atorvastatin Attenuates Diet-Induced Non-Alcoholic Steatohepatitis in APOE*3-Leiden Mice by Reducing Hepatic Inflammation.
    International journal of molecular sciences, 2023, Apr-25, Volume: 24, Issue:9

    Topics: Animals; Apolipoproteins E; Atorvastatin; Cholesterol; Diet; Inflammasomes; Inflammation; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease

2023
Protective effects of statins on the incidence of NAFLD-related decompensated cirrhosis in T2DM.
    Liver international : official journal of the International Association for the Study of the Liver, 2023, Volume: 43, Issue:10

    Topics: Atorvastatin; Diabetes Mellitus, Type 2; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Non-alcoholic Fatty Liver Disease; Risk Factors

2023
Atorvastatin and Vitamin E Accelerates NASH Resolution by Dietary Intervention in a Preclinical Guinea Pig Model.
    Nutrients, 2019, Nov-19, Volume: 11, Issue:11

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Atorvastatin; Caloric Restriction; Combined Modality Therapy; Female; Guinea Pigs; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lipids; Liver; Liver Cirrhosis, Experimental; Non-alcoholic Fatty Liver Disease; Time Factors; Vitamin E

2019
All-Trans Retinoic Acid (atRA) effectively improves liver steatosis in a rabbit model of high fat induced liver steatosis.
    Archives of physiology and biochemistry, 2022, Volume: 128, Issue:4

    Topics: Animals; Antioxidants; Atorvastatin; Diet, High-Fat; Humans; Hyperlipidemias; Liver; Male; Non-alcoholic Fatty Liver Disease; Rabbits; Tretinoin

2022
Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites.
    Gut, 2021, Volume: 70, Issue:4

    Topics: Animals; Atorvastatin; Carcinoma, Hepatocellular; Case-Control Studies; Cholesterol, Dietary; Disease Progression; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease

2021
Synergic effect of atorvastatin and ambrisentan on sinusoidal and hemodynamic alterations in a rat model of NASH.
    Disease models & mechanisms, 2021, 05-01, Volume: 14, Issue:5

    Topics: Alanine Transaminase; Animals; Atorvastatin; Biomarkers; Collagen; Disease Models, Animal; Drug Synergism; Endothelial Cells; Endothelin-1; Enzyme Activation; Hemodynamics; Hepatic Stellate Cells; Insulin Resistance; Liver; Liver Cirrhosis; Nitric Oxide Synthase Type III; Non-alcoholic Fatty Liver Disease; Phenylpropionates; Pyridazines; Weight Gain

2021
Atorvastatin Modulates Bile Acid Homeostasis in Mice with Diet-Induced Nonalcoholic Steatohepatitis.
    International journal of molecular sciences, 2021, Jun-16, Volume: 22, Issue:12

    Topics: Animals; Atorvastatin; Bile Acids and Salts; Biomarkers; Diet, High-Fat; Disease Models, Animal; Homeostasis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Mice; Models, Biological; Non-alcoholic Fatty Liver Disease; Triglycerides

2021
Anti hyperlipidemic and hepatoprotective effects of native date fruit variety "Aseel" (Phoenix dactylifera).
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:6

    Topics: Animals; Atorvastatin; Biomarkers; Blood Glucose; Cytoprotection; Diet, High-Fat; Dietary Sucrose; Disease Models, Animal; Fruit; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Lipids; Liver; Male; Non-alcoholic Fatty Liver Disease; Phoeniceae; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats; Time Factors

2016
Letter to the editor: Treating nonalcoholic fatty liver disease with statins. Are all statins equal?
    American journal of physiology. Gastrointestinal and liver physiology, 2017, 06-01, Volume: 312, Issue:6

    Topics: Atorvastatin; Comorbidity; Coronary Disease; Evidence-Based Medicine; Humans; Longitudinal Studies; Non-alcoholic Fatty Liver Disease; Prevalence; Risk Factors; Rosuvastatin Calcium; Treatment Outcome

2017
(-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis-related genes in non-alcoholic fatty liver disease.
    Clinical and experimental pharmacology & physiology, 2017, Volume: 44, Issue:12

    Topics: Animals; Atorvastatin; Catechin; Disease Models, Animal; Down-Regulation; Fibrillar Collagens; Gene Expression; Humans; Liver Cirrhosis; Male; Mice, Inbred C57BL; Multigene Family; Non-alcoholic Fatty Liver Disease

2017
Atorvastatin reduces lipid accumulation in the liver by activating protein kinase A-mediated phosphorylation of perilipin 5.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2017, Volume: 1862, Issue:12

    Topics: Amino Acid Substitution; Animals; Atorvastatin; Cyclic AMP-Dependent Protein Kinases; Dietary Fats; Intracellular Signaling Peptides and Proteins; Lipolysis; Liver; Male; Mice; Mice, Knockout; Muscle Proteins; Mutation, Missense; Non-alcoholic Fatty Liver Disease; Phosphorylation; Triglycerides

2017
Activation of hepatic Nogo-B receptor expression-A new anti-liver steatosis mechanism of statins.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2018, Volume: 1863, Issue:2

    Topics: Animals; Atorvastatin; Gene Expression Regulation; Hep G2 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Liver; Liver X Receptors; MAP Kinase Signaling System; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 3; Non-alcoholic Fatty Liver Disease; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface

2018
Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome.
    Journal of hepatology, 2013, Volume: 59, Issue:1

    Topics: Adiponectin; Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Diabetes Complications; Drug Therapy, Combination; Ezetimibe; Fatty Liver; Female; Heptanoic Acids; Insulin; Liver; MAP Kinase Signaling System; Metabolic Syndrome; Mice; Mice, Mutant Strains; Mice, Obese; Non-alcoholic Fatty Liver Disease; Pyrroles

2013
Are statins 'IDEAL' for non-alcoholic fatty liver disease?
    Current medical research and opinion, 2014, Volume: 30, Issue:2

    Topics: Atorvastatin; Carcinoma, Hepatocellular; Cardiovascular Diseases; Dyslipidemias; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Liver; Liver Neoplasms; Male; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Triglycerides

2014
APOE*3Leiden.CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome.
    Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Apolipoprotein E3; Atorvastatin; Cholesterol Ester Transfer Proteins; Disease Models, Animal; Fenofibrate; Glucagon-Like Peptide 1; Heptanoic Acids; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Liraglutide; Male; Metabolic Syndrome; Mice, Transgenic; Niacin; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Rosiglitazone; Thiazolidinediones

2014
Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH.
    Journal of lipid research, 2015, Volume: 56, Issue:2

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Cholesterol; Ezetimibe; Female; Heptanoic Acids; Inflammasomes; Kupffer Cells; Liver; Mice; Mice, Mutant Strains; Non-alcoholic Fatty Liver Disease; Pyrroles

2015
[Negative effects of termination statinotherapy in patients after acute coronary event with concominent non-alcoholic steatohepatitis].
    Likars'ka sprava, 2014, Issue:11

    Topics: Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Drug Administration Schedule; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Myocardial Infarction; Non-alcoholic Fatty Liver Disease; Pyrimidines; Pyrroles; Recurrence; Rosuvastatin Calcium; Sulfonamides; Triglycerides

2014
Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis.
    Prostaglandins, leukotrienes, and essential fatty acids, 2015, Volume: 96

    Topics: Animals; Atorvastatin; Body Weight; Cytokines; Diet, High-Fat; Disease Models, Animal; Fatty Acids, Omega-3; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Insulin Resistance; Lipids; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats, Wistar; Sucrose

2015
Acute atorvastatin is hepatoprotective against ischaemia-reperfusion injury in mice by modulating eNOS and microparticle formation.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:9

    Topics: Animals; Atorvastatin; Chemokines; Cytokines; HMGB1 Protein; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Mice; Mice, Obese; NF-kappa B; Nitric Oxide Synthase Type III; Non-alcoholic Fatty Liver Disease; Reperfusion Injury; Thromboxane B2; Toll-Like Receptor 4; Vascular Cell Adhesion Molecule-1

2015
Effect of diet/atorvastatin on atherosclerotic lesions associated to nonalcoholic fatty liver disease in chickens.
    Histology and histopathology, 2015, Volume: 30, Issue:12

    Topics: Animals; Arteries; Atherosclerosis; Atorvastatin; Chickens; Diet; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Male; Non-alcoholic Fatty Liver Disease

2015
Effect of combined use of Fructus Schisandrae and statin on high-fat-diet-induced metabolic syndrome in rats.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2016, Volume: 22 Suppl 6, Issue:6

    Topics: Animals; Atorvastatin; Cytochrome P-450 CYP3A; Diet, High-Fat; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Schisandra

2016
Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment.
    Toxicology and applied pharmacology, 2011, Feb-15, Volume: 251, Issue:1

    Topics: Animals; Atorvastatin; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cyclic AMP-Dependent Protein Kinases; Dietary Carbohydrates; Disease Models, Animal; Down-Regulation; Fatty Acids; Fatty Liver; Fructokinases; Fructose; Gene Expression Regulation; Hepatitis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; I-kappa B Proteins; Inflammation Mediators; Lipid Metabolism; Liver; Male; Metallothionein; Necrosis; NF-kappa B; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; Triglycerides

2011
Metformin and atorvastatin combination further protect the liver in type 2 diabetes with hyperlipidaemia.
    Diabetes/metabolism research and reviews, 2011, Volume: 27, Issue:1

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Body Weight; C-Reactive Protein; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Combinations; Fatty Liver; Heptanoic Acids; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Interleukin-6; Liver; Metformin; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Pyrroles; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha

2011
Comparison of dietary control and atorvastatin on high fat diet induced hepatic steatosis and hyperlipidemia in rats.
    Lipids in health and disease, 2011, Jan-26, Volume: 10

    Topics: Animals; Atorvastatin; Combined Modality Therapy; Dietary Fats; Fatty Liver; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipid Metabolism; Lipids; Liver; Male; Non-alcoholic Fatty Liver Disease; Organ Size; PPAR alpha; Pyrroles; Rats; Rats, Sprague-Dawley; Sterol Regulatory Element Binding Protein 1; Transaminases

2011
Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:6

    Topics: Adiponectin; Adult; Alanine Transaminase; Anticholesteremic Agents; Aspartate Aminotransferases; Atorvastatin; Blood Glucose; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Collagen Type IV; Dyslipidemias; Fatty Liver; Female; gamma-Glutamyltransferase; Heptanoic Acids; Humans; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Pyrroles; Regression Analysis; Severity of Illness Index; Triglycerides; Tumor Necrosis Factor-alpha

2012
Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4 suppression and endothelial nitric oxide synthase activation.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:8

    Topics: Administration, Oral; Animals; Atorvastatin; Cell Adhesion Molecules; Cytokines; Cytoprotection; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Enzyme Activation; Fatty Liver; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Injections, Intravenous; Liver; Male; Mice; Mice, Obese; NF-kappa B; Nitric Oxide Synthase Type III; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Reperfusion Injury; RNA, Messenger; Thromboxane B2; Time Factors; Toll-Like Receptor 4

2012
If steatosis is the atherosclerosis of the liver, are statins the "aspirin" for steatosis?
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2012, Volume: 44, Issue:6

    Topics: Anticholesteremic Agents; Atorvastatin; Dyslipidemias; Fatty Liver; Female; Heptanoic Acids; Humans; Male; Non-alcoholic Fatty Liver Disease; Pyrroles; Tumor Necrosis Factor-alpha

2012
Enhancing organ pool by statins: is this the future?
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:8

    Topics: Animals; Atorvastatin; Fatty Liver; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Nitric Oxide Synthase Type III; Non-alcoholic Fatty Liver Disease; Obesity; Pyrroles; Reperfusion Injury; Toll-Like Receptor 4

2012