atorvastatin has been researched along with Cardiomegaly in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (37.50) | 29.6817 |
| 2010's | 13 (54.17) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bian, Z; Chen, X; Gu, Y; Hu, R; Li, L; Liu, N; Ma, W; Wu, H; Yang, D; Zheng, P | 1 |
| Dong, S; Feng, Y; Jiang, Q; Li, J; Li, S; Li, T; Lin, W; Liu, B; Luo, H; Ou, Z; Qi, Q; Xu, Q; Yu, Z; Zeng, X; Zha, L; Zhang, M; Zhao, L | 1 |
| Fu, H; Liu, X; Lu, L; Wu, S; Wu, W; Zhao, M | 1 |
| Hu, Y; Jin, M; Li, GC; Liu, HG; Liu, W; Ren, J; You, ZX | 1 |
| Cheng, WP; Chua, SK; Lo, HM; Shyu, KG; Wang, BW | 1 |
| Fukumoto, Y; Kudo, S; Liao, JK; Minami, T; Nochioka, K; Shiba, N; Shimokawa, H; Takai, Y; Tanaka, S; Williams, CL | 1 |
| Amini, R; Jahanbakhsh, Z; Mohammadi, MT; Shekarforoush, S | 1 |
| Bu, L; Cheng, Z; Dong, D; Huang, T; Shen, B; Tu, Y; Wan, L; Zhao, D | 1 |
| Deng, Y; Guo, X; Liu, H; Shang, J; Yuan, X; Zhu, D | 1 |
| Cui, W; Du, H; Hao, J; Liu, D; Liu, F; Lu, J; Yang, X | 1 |
| Han, CG; Liu, YX; Sheng, L; Yang, X; Ye, P | 1 |
| Chen, F; Chen, H; Cui, W; Jin, Y; Liu, D; Liu, F; Lu, J | 1 |
| Bi, C; Cao, X; Ding, F; Feng, D; Han, Z; Huang, Q; Liang, J; Liu, Y; Ma, W; Pan, Z; Yin, K; Zhang, L | 1 |
| Ehmke, H; El-Armouche, A; Eschenhagen, T; Grimm, M; Höppner, G; Schmechel, A; Schwoerer, AP | 1 |
| Cui, W; Du, J; Han, M; Liu, DM; Liu, F; Lu, JC; Yin, HN; Zhang, HL; Zhang, K | 1 |
| Lombardi, R; Marian, AJ; Nagueh, SF; Tan, Y; Wang, J; Willerson, JT | 1 |
| Liu, XG; Miao, N; Mu, SH; Sui, MS; Xie, RJ; Zhao, SL | 1 |
| Laguna, JC; Planavila, A; Vázquez-Carrera, M | 1 |
| Liu, YX; Sheng, L; Ye, P | 1 |
| Ge, CJ; Hu, SJ; Kang, L | 1 |
| Fang, Q; Hu, SJ; Kang, L | 1 |
| Bezerra, DG; Lacerda Andrade, LM; Mandarim-de-Lacerda, CA; Pinto da Cruz, FO | 1 |
| Asakura, M; Asanuma, H; Kato, H; Kim, J; Kitakaze, M; Liao, Y; Minamino, T; Ogai, A; Takashima, S; Zhao, H | 1 |
| Böhm, M; Kilter, H; Konkol, C; Laufs, U; Nickenig, G; Wassmann, S | 1 |
1 trial(s) available for atorvastatin and Cardiomegaly
| Article | Year |
|---|---|
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Atorvastatin; Biomarkers; Cardiomegaly; Cells, Cultured; Cholesterol; Cholesterol, LDL; Coronary Vessels; Cross-Over Studies; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanine Nucleotide Exchange Factors; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Male; Mice; Mice, Knockout; Neuropeptides; Oxidative Stress; Phosphatidylinositol 3-Kinase; Pravastatin; Proto-Oncogene Proteins c-akt; Pyrroles; Quinolines; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; RNA Interference; Signal Transduction; Transfection | 2013 |
23 other study(ies) available for atorvastatin and Cardiomegaly
| Article | Year |
|---|---|
Atorvastatin ameliorates lipid overload-induced mitochondrial dysfunction and myocardial hypertrophy by decreasing fatty acid oxidation through inactivation of the p-STAT3/CPT1 pathway.
Topics: Animals; Atorvastatin; Cardiomegaly; Carnitine O-Palmitoyltransferase; Fatty Acids; Mice; Mitochondria; Myocytes, Cardiac; Palmitic Acid; Rats; STAT3 Transcription Factor | 2023 |
Combination of Dichloroacetate and Atorvastatin Regulates Excessive Proliferation and Oxidative Stress in Pulmonary Arterial Hypertension Development via p38 Signaling.
Topics: Animals; Apoptosis; Atorvastatin; Cardiomegaly; Cell Proliferation; Cell Survival; Dichloroacetic Acid; Endoplasmic Reticulum Stress; Hemodynamics; Inflammation; Macrophages; Male; Mitochondria; Models, Biological; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pulmonary Arterial Hypertension; Rats, Sprague-Dawley; Signal Transduction | 2020 |
[Study on Potential Role of Calreticulin in Pressure Overload Induced Cardiac Hypertrophy].
Topics: Animals; Apoptosis; Atorvastatin; Calreticulin; Cardiomegaly; Cells, Cultured; Endoplasmic Reticulum Stress; Male; Myocytes, Cardiac; Pressure; Rats; Rats, Sprague-Dawley | 2016 |
Atorvastatin Attenuates Myocardial Hypertrophy Induced by Chronic Intermittent Hypoxia In Vitro Partly through miR-31/PKCε Pathway.
Topics: Animals; Atorvastatin; Cardiomegaly; Cardiotonic Agents; Cell Line; Chronic Disease; Hypoxia; MicroRNAs; Myocardium; Myocytes, Cardiac; Protein Kinase C-epsilon; Rats; Signal Transduction; Up-Regulation | 2018 |
Effect of atorvastatin on cardiomyocyte hypertrophy through suppressing MURC induced by volume overload and cyclic stretch.
Topics: Angiotensin II; Animals; Anticholesteremic Agents; Arteriovenous Shunt, Surgical; Atorvastatin; Cardiomegaly; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Male; Muscle Proteins; Myocytes, Cardiac; Rats; Rats, Wistar; Signal Transduction; Stress, Mechanical | 2019 |
Effects of atorvastatin on the hypertension-induced oxidative stress in the rat brain.
Topics: Animals; Atorvastatin; Blood Pressure; Brain; Cardiomegaly; Catalase; Glutathione; Heptanoic Acids; Hypertension; Male; Malondialdehyde; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Superoxide Dismutase | 2013 |
MicroRNA-22 downregulation by atorvastatin in a mouse model of cardiac hypertrophy: a new mechanism for antihypertrophic intervention.
Topics: Angiotensin II; Animals; Anticholesteremic Agents; Atorvastatin; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Down-Regulation; Heptanoic Acids; Male; Mice; MicroRNAs; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain; Oligonucleotides, Antisense; Phosphoric Monoester Hydrolases; PTEN Phosphohydrolase; Pyrroles; Rats | 2013 |
Atorvastatin attenuates myocardial remodeling induced by chronic intermittent hypoxia in rats: partly involvement of TLR-4/MYD88 pathway.
Topics: Animals; Atorvastatin; Cardiomegaly; Cytokines; Heart; Heptanoic Acids; Hypoxia; Male; Myeloid Differentiation Factor 88; Myocardium; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Sleep Apnea, Obstructive; Toll-Like Receptor 4; Ventricular Remodeling | 2014 |
Amlodipine and atorvastatin improved hypertensive cardiac hypertrophy through regulation of receptor activator of nuclear factor kappa B ligand/receptor activator of nuclear factor kappa B/osteoprotegerin system in spontaneous hypertension rats.
Topics: Administration, Oral; Amlodipine; Animals; Antihypertensive Agents; Atorvastatin; Cardiomegaly; Cross-Sectional Studies; Disease Models, Animal; Gene Expression Profiling; Hydroxyproline; Hypertension; Immunohistochemistry; Male; Myocardium; NF-kappa B; Osteoprotegerin; RANK Ligand; Rats, Inbred SHR; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Treatment Outcome; Ventricular Function, Left | 2016 |
Effect of Atorvastatin on Expression of Peroxisome Proliferator-activated Receptor Beta/delta in Angiotensin II-induced Hypertrophic Myocardial Cells In Vitro.
Topics: Angiotensin II; Animals; Atorvastatin; Cardiomegaly; Cells, Cultured; Hydroxymethylglutaryl-CoA Reductase Inhibitors; PPAR delta; PPAR-beta; Rats; Rats, Wistar | 2015 |
Amlodipine and atorvastatin improve ventricular hypertrophy and diastolic function via inhibiting TNF-α, IL-1β and NF-κB inflammatory cytokine networks in elderly spontaneously hypertensive rats.
Topics: Aging; Amlodipine; Animals; Atorvastatin; C-Reactive Protein; Cardiomegaly; Diastole; Heart Ventricles; I-kappa B Proteins; Inflammation; Interleukin-1beta; Male; Myocardium; NF-kappa B; Rats, Inbred SHR; Rats, Inbred WKY; Tumor Necrosis Factor-alpha | 2016 |
Attenuation of Low Ambient Temperature-Induced Myocardial Hypertrophy by Atorvastatin via Promoting Bcl-2 Expression.
Topics: Animals; Atorvastatin; Autophagy; bcl-2-Associated X Protein; Blood Pressure; Cardiomegaly; Cold Temperature; Down-Regulation; Echocardiography; Heart Ventricles; JNK Mitogen-Activated Protein Kinases; Male; Mice; Microscopy, Electron, Transmission; Mitogen-Activated Protein Kinases; Myocardium; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2017 |
Treatment with atorvastatin partially protects the rat heart from harmful catecholamine effects.
Topics: Adrenergic beta-Agonists; Animals; Atorvastatin; Atrial Natriuretic Factor; Cardiomegaly; Cell Membrane; Circadian Rhythm; Cytosol; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Protein gamma Subunits; Heart; Heart Rate; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusion Pumps, Implantable; Isoproterenol; Male; Myocardial Contraction; Myocardium; Protein Transport; Pyrroles; Rats; Rats, Wistar; RNA, Messenger | 2009 |
Additive beneficial effects of amlodipine and atorvastatin in reversing advanced cardiac hypertrophy in elderly spontaneously hypertensive rats.
Topics: Aging; Amlodipine; Animals; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Cardiomegaly; Drug Synergism; Drug Therapy, Combination; Fibrosis; Heart Failure, Diastolic; Hemodynamics; Heptanoic Acids; Myocytes, Cardiac; NADPH Oxidases; Natriuretic Peptide, Brain; Oxidative Stress; Pyrroles; Random Allocation; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Superoxide Dismutase; Ventricular Dysfunction, Left | 2009 |
Atorvastatin and cardiac hypertrophy and function in hypertrophic cardiomyopathy: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cardiomegaly; Cardiomyopathy, Hypertrophic; Death, Sudden, Cardiac; Female; Genetic Predisposition to Disease; Heptanoic Acids; Humans; Male; Middle Aged; Pilot Projects; Pyrroles; Statistics as Topic; Treatment Outcome; Young Adult | 2010 |
[Atorvastatin attenuates parathyroid hormone 1-34 induced cardiomyocytes hypertrophy through downregulating K-Ras-ERK1/2 pathway].
Topics: Animals; Animals, Newborn; Atorvastatin; Cardiomegaly; Cells, Cultured; Heptanoic Acids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Parathyroid Hormone; Pyrroles; Rats; Rats, Wistar | 2012 |
Atorvastatin improves peroxisome proliferator-activated receptor signaling in cardiac hypertrophy by preventing nuclear factor-kappa B activation.
Topics: Animals; Atorvastatin; Cardiomegaly; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Pressure; Protein Isoforms; Protein Subunits; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2005 |
[Atorvastatin upregulates the expression of PPAR alpha/gamma and inhibits the hypertrophy of cardiac myocytes in vitro].
Topics: Angiotensin II; Animals; Atorvastatin; Cardiomegaly; Cells, Cultured; Gene Expression Regulation; Heptanoic Acids; Myocytes, Cardiac; PPAR alpha; PPAR-beta; Pyrroles; Rats; Rats, Wistar; Up-Regulation | 2005 |
Beneficial effect of atorvastatin on left ventricular remodeling in spontaneously hypertensive rats.
Topics: Animals; Apoptosis; Atorvastatin; Blood Pressure; Cardiomegaly; Collagen; Cyclin-Dependent Kinase Inhibitor p27; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Myocardium; Pyrroles; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Remodeling | 2007 |
Regulation of phospholamban and sarcoplasmic reticulum Ca2+-ATPase by atorvastatin: implication for cardiac hypertrophy.
Topics: Animals; Atorvastatin; Calcium-Binding Proteins; Cardiomegaly; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Systole | 2007 |
Atorvastatin attenuates cardiomyocyte loss in adult rats from protein-restricted dams.
Topics: Animals; Atorvastatin; Blood Pressure; Body Mass Index; Cardiomegaly; Diet, Protein-Restricted; Fibrosis; Heptanoic Acids; Hypertrophy, Left Ventricular; Male; Myocardial Reperfusion; Myocytes, Cardiac; Perfusion; Pyrroles; Rats; Rats, Wistar | 2008 |
Atorvastatin slows the progression of cardiac remodeling in mice with pressure overload and inhibits epidermal growth factor receptor activation.
Topics: Animals; Atorvastatin; Cardiomegaly; Disease Progression; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Heart Failure; Heparin-binding EGF-like Growth Factor; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Natriuretic Peptide, Brain; Phosphorylation; Pyrroles; Ventricular Function, Left | 2008 |
Impact of HMG CoA reductase inhibition on small GTPases in the heart.
Topics: Angiotensin II; Animals; Atorvastatin; Atrial Natriuretic Factor; Cardiac Myosins; Cardiomegaly; Cell Membrane; Cells, Cultured; Gene Expression Regulation; GTP Phosphohydrolases; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Myocardium; Myosin Light Chains; Pyrroles; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; RNA, Messenger; Simvastatin | 2002 |