Compounds > atorvastatin
Page last updated: 2024-08-24

atorvastatin and Brain Neoplasms

atorvastatin has been researched along with Brain Neoplasms in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Aldanan, S; Alghareeb, WA; Alhussain, H; AlNajjar, FH; Alsaeed, E; Alsharm, AA; Altwairgi, AK; Balbaid, AAO; Orz, Y1
Gao, X; Gu, Y; Li, J; Qin, J; Sun, C; Xiao, L; Yang, H; Yang, R; Yang, Y; Ye, J; Yuan, Y; Zhang, F; Zhang, J; Zhang, L; Zhao, Y1
Li, J; Long, C; Peng, P; Wei, W1
Lei, C; Shuyun, H; Xiangrong, C; Yiquan, K; Yongjun, Y; Zhilin, Y1
Dal-Cim, T; Lopes, FG; Ludka, FK; Nedel, CB; Oliveira, KA; Tasca, CI1
Ai, A; Ai, J; Ardakan, MMM; Bayat, N; Ebrahimi-Barough, S; Norouzi-Javidan, A; Saberi, H; Soleimannejad, M1
de Barros e Silva, MJ; de Paiva, TF; Fanelli, MF; Gimenes, DL; Rinck, JA1

Trials

1 trial(s) available for atorvastatin and Brain Neoplasms

ArticleYear
Atorvastatin in combination with radiotherapy and temozolomide for glioblastoma: a prospective phase II study.
    Investigational new drugs, 2021, Volume: 39, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans; Male; Middle Aged; Progression-Free Survival; Prospective Studies; Temozolomide; Young Adult

2021

Other Studies

6 other study(ies) available for atorvastatin and Brain Neoplasms

ArticleYear
Isocitrate dehydrogenase 1 mutation enhances 24(S)-hydroxycholesterol production and alters cholesterol homeostasis in glioma.
    Oncogene, 2020, Volume: 39, Issue:40

    Topics: Animals; Astrocytes; Atorvastatin; Brain; Brain Neoplasms; Cell Line, Tumor; Gene Knock-In Techniques; Glioma; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isocitrate Dehydrogenase; Mice; Mice, Transgenic; Mutation; Myelin Sheath; Primary Cell Culture

2020
Atorvastatin augments temozolomide's efficacy in glioblastoma via prenylation-dependent inhibition of Ras signaling.
    Biochemical and biophysical research communications, 2017, 07-29, Volume: 489, Issue:3

    Topics: Animals; Atorvastatin; Brain Neoplasms; Cell Proliferation; Cell Survival; Dacarbazine; Disease Models, Animal; Glioblastoma; Humans; Mice; Neoplasms, Experimental; ras Proteins; Signal Transduction; Temozolomide; Tumor Cells, Cultured

2017
Atorvastatin suppresses glioma invasion and migration by reducing microglial MT1-MMP expression.
    Journal of neuroimmunology, 2013, Jul-15, Volume: 260, Issue:1-2

    Topics: Atorvastatin; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioblastoma; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MAP Kinase Signaling System; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Microglia; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pyrroles

2013
Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells.
    Molecular neurobiology, 2018, Volume: 55, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Atorvastatin; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Synergism; Glioma; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Temozolomide

2018
Anti-inflammatory Effects of Atorvastatin in Human Glioblastoma Spheroids Cultured in a Three-dimensional Model: Possible Relevance to Glioblastoma Treatment.
    Molecular neurobiology, 2018, Volume: 55, Issue:3

    Topics: Anti-Inflammatory Agents; Atorvastatin; Brain Neoplasms; Cell Culture Techniques; Cell Proliferation; Dose-Response Relationship, Drug; Glioblastoma; Humans; Inflammation Mediators; Spheroids, Cellular; Treatment Outcome

2018
Tuberculosis in a patient on temozolomide: a case report.
    Journal of neuro-oncology, 2009, Volume: 92, Issue:1

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Combined Modality Therapy; Cyclosporine; Dacarbazine; Dexamethasone; Female; Fluoxetine; Glioblastoma; Heptanoic Acids; Humans; Immunosuppressive Agents; Isoniazid; Middle Aged; Omeprazole; Phenobarbital; Prednisone; Pyrazinamide; Pyrroles; Radiotherapy; Red-Cell Aplasia, Pure; Rifampin; Temozolomide; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Pulmonary

2009