atorvastatin has been researched along with Body Weight in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.39) | 18.2507 |
| 2000's | 23 (38.98) | 29.6817 |
| 2010's | 30 (50.85) | 24.3611 |
| 2020's | 4 (6.78) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, L; Chen, B; Han, J; Liu, H; Luo, H; Ma, K; Ren, J; Wang, K; Zhang, J | 1 |
| Chen, C; Hu, N; Huang, J; Li, C; Wang, J; Yao, D | 1 |
| Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP | 1 |
| Klinnikova, MG; Koldysheva, EV; Lushnikova, EL; Semenov, DE; Tursunova, NV | 1 |
| Abdel-Gabbar, M; Anwar, S; El-Zanaty, AM; Esmail, M; Kandeil, M | 1 |
| Huang, D; Liu, H; Niu, T; Wang, K; Yang, J | 1 |
| Alencar, NM; Benevides, NM; Goes, P; Lima, V; Melo, IM; Ribeiro, RA; Silva, LM | 1 |
| Marrion, NV; Robertson, JD; Robinson, ES; Stuart, SA | 1 |
| Khoramjouy, M; Malekinejad, H; Mehrabi, M; Rezaei-Golmisheh, A | 1 |
| Abreu, GR; Andrade, TU; Bissoli, NS; Caliman, IF; Dalpiaz, PL; Figueiredo, SG; Gusmão, LN; Lamas, AZ; Medeiros, AR | 1 |
| Dang, XM; Ma, AQ; Yang, L; Zhu, B | 1 |
| Ceron, CS; Gerlach, RF; Guimarães, DA; Pinheiro, LC; Rizzi, E; Tanus-Santos, JE | 1 |
| Du, Y; Gao, J; Hu, R; Lu, M; Wang, Y; Wei, W; Zhang, S; Zhou, Q; Zhu, H; Zuo, L | 1 |
| Fu, G; Gong, X; Ma, Y; Ruan, Y; Wu, S | 1 |
| Aslam, M; Bhattacharya, SK; Galav, V; Jafri, AA; Madhu, SV | 1 |
| Abdelbary, A; Hamza, M; Unis, A | 1 |
| Chang, CY; Chang, KC; Chang, RW; Chen, YS; Ko, WJ; Ko, YH; Tsai, PR; Wang, CH; Wang, SS; Young, TH | 1 |
| Barter, PJ; DeMicco, DA; Messig, M; Ong, KL; Rye, KA; Waters, DD | 1 |
| Chi, L; Hu, X; Pan, N; Peng, L; Zhang, Y | 1 |
| Bento, CF; Fernandes, R; Matafome, P; Pereira, P; Seiça, RM; Sena, CM | 1 |
| Abd Elmaaboud, MA; Albarraq, AA; Kabel, AM | 1 |
| Cheung, DW; Fung, KP; Koon, CM; Lau, CB; Lau, CP; Leung, PC; Ng, CF; Wat, E; Wong, EC | 1 |
| Harada, M; Otsuki, M; Wei, L; Yamamoto, M | 1 |
| Aggarwal, S; Aslam, M; Galav, V; Madhu, SV; Sharma, KK | 1 |
| Abdallah, D; El-Ganainy, SO; El-Khatib, AS; El-Mallah, A; Khattab, MM; Mohy El-Din, MM | 1 |
| Chen, Y; Dai, YT; Tang, L; Yu, W; Zhang, Z | 1 |
| Bardou, M; Dumas, M; Goirand, F; Guerard, P; Lirussi, F; Rakotoniaina, Z; Rochette, L | 1 |
| Dhaliwal, S; Galloway, S; Jian, L; Johnsen, R; Mamo, JC; Pallebage-Gamarallage, MM | 1 |
| Chen, IJ; Hsieh, SL; Kwan, AL; Lin, HL; Shen, KP; Wu, BN | 1 |
| Boyle, A; Connelly, KA; Gilbert, RE; Kelly, D; Kompa, A; Krum, H; Martin, JH; Zhang, Y | 1 |
| Arany, EJ; Hill, DJ; Marchand, KC | 1 |
| Kalonia, H; Kumar, A; Kumar, P | 1 |
| Chen, P; Duan, S; Gan, Y; Jiang, LZ; Li, GY; Wu, SJ; Zhang, J; Zhang, Y; Zhao, SP | 1 |
| Abe, K; Ikeda, Y; Kozuki, M; Kurata, T; Matsuura, T; Miyazaki, K; Morimoto, N; Nagai, M; Ohta, Y; Panin, VL | 1 |
| Amaral, C; Cipriano, A; Crisóstomo, J; Louro, T; Matafome, P; Monteiro, P; Nunes, E; Rodrigues, L; Seiça, R | 1 |
| Andersson, KE; Eussen, SR; Garssen, J; Hellstrand, P; Klungel, OH; Oste, R; Rompelberg, CJ; van Kranen, H | 1 |
| Andalib, S; Biabani, S; Doustar, Y; Garjani, A; Maleki-Dizaji, N; Soraya, H | 1 |
| Barrett, PH; Beilin, LJ; Chan, DC; Mori, TA; Redgrave, TG; Watts, GF | 1 |
| Abe, K; Deguchi, K; Hayashi, T; Nagano, I; Nagotani, S; Sato, K; Shoji, M; Zhang, W | 1 |
| Fantus, IG; Lewis, GF; Stavar, L; Szeto, L; Uffelman, K; Wang, CH; Wong, V | 1 |
| Deng, P; Hong, SC; Wu, J; Wu, ZH; Zhao, SP | 1 |
| Ichihara, K; Kanda, M; Kasai, T; Keimatsu, N; Satoh, K; Sun, F; Takaguri, A | 1 |
| Donkin, SS; Elkin, RG; Hengstschläger-Ottnad, E; Schneider, WJ; Zhong, Y | 1 |
| Balaraman, R; Bothara, SB; Majithiya, JB; Trivedi, CJ | 1 |
| Huang, TG; Mondo, CK; Su, JZ; Yang, WS | 2 |
| Chiesa, G; Cippone, V; Conte Camerino, D; De Luca, A; De Vito, D; Didonna, MP; Frigeri, A; Nicchia, GP; Pierno, S; Pisoni, M; Rizzo, C; Scanziani, E; Sirtori, C; Svelto, M | 1 |
| Gorbas', IM; Iakimishina, LI; Kaĭdashev, IP; Petrushov, AV; Rasin, AM; Rasin, MS; Smirnova, IP; Vasil'ev, VN | 1 |
| Frost, RJ; Otto, B; Otto, C; Parhofer, KG; Pfeiffer, AF; Spranger, J; Vogeser, M | 1 |
| Parle, M; Singh, N | 1 |
| Birnbaum, Y; Huang, MH; Hughes, MG; Lin, Y; Lui, CY; Manickavasagam, S; McAdoo, DJ; Perez-Polo, RJ; Uretsky, BF; Ye, Y | 1 |
| Bauersachs, J; Brandt, M; Closs, E; Daiber, A; Ertl, G; Förstermann, U; Münzel, T; Oelze, M; Thum, T; Wenzel, P; Xu, J; Zou, MH | 1 |
| De Angelis, S; De Lorenzo, A; Di Daniele, N; Di Renzo, L; Miani, N; Noce, A; Tozzo, C | 1 |
| Ballerini, C; Bellucci, A; Biagioli, T; Biamonte, F; Casamenti, F; Grossi, C; Luccarini, I; Massacesi, L; Rosi, MC | 1 |
| Bujo, H; Hanaoka, H; Kodama, T; Mikami, K; Miyashita, Y; Nishikawa, T; Saito, Y; Shinomiya, M; Tada, N; Yokote, K | 1 |
| Anderson, JA; Dostal, LA; Schardein, JL | 1 |
| Anderson, JA; Black, A; Colgin, J; Craft, WR; Henck, JW | 1 |
| Beinlich, CJ; Ichihara, K; Morgan, HE; Satoh, K; Shirota, F; Tsunajima, T | 1 |
| Boquist, S; Danell-Toverud, K; Hamsten, A; Karpe, F | 1 |
5 trial(s) available for atorvastatin and Body Weight
| Article | Year |
|---|---|
Effect of change in body weight on incident diabetes mellitus in patients with stable coronary artery disease treated with atorvastatin (from the treating to new targets study).
Topics: Atorvastatin; Body Weight; Coronary Artery Disease; Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Global Health; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Incidence; Life Style; Male; Middle Aged; Pyrroles; Risk Factors; Time Factors; Weight Loss | 2014 |
Regulatory effects of HMG CoA reductase inhibitor and fish oils on apolipoprotein B-100 kinetics in insulin-resistant obese male subjects with dyslipidemia.
Topics: Apolipoprotein B-100; Apolipoproteins B; Atorvastatin; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Fasting; Fatty Acids, Nonesterified; Fish Oils; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Insulin; Insulin Resistance; Kinetics; Male; Middle Aged; Obesity; Placebos; Pyrroles | 2002 |
Short-term therapy with atorvastatin or fenofibrate does not affect plasma ghrelin, resistin or adiponectin levels in type 2 diabetic patients with mixed hyperlipoproteinaemia.
Topics: Adiponectin; Aged; Atorvastatin; Body Mass Index; Body Weight; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Fenofibrate; Ghrelin; Glycated Hemoglobin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemias; Hypolipidemic Agents; Male; Middle Aged; Peptide Hormones; Pyrroles; Resistin | 2007 |
Multicenter collaborative randomized parallel group comparative study of pitavastatin and atorvastatin in Japanese hypercholesterolemic patients: collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis preventi
Topics: Aged; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Body Mass Index; Body Weight; Cholesterol, LDL; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Japan; Male; Middle Aged; Pyrroles; Quinolines; Waist Circumference | 2008 |
Effects of atorvastatin on postprandial plasma lipoproteins in postinfarction patients with combined hyperlipidaemia.
Topics: Adult; Analysis of Variance; Atorvastatin; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Chylomicron Remnants; Chylomicrons; Cross-Over Studies; Double-Blind Method; Drug Evaluation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemia, Familial Combined; Lipids; Lipoproteins; Male; Middle Aged; Myocardial Infarction; Patient Compliance; Postprandial Period; Pyrroles; Sweden; Time Factors; Treatment Outcome; Triglycerides | 2002 |
54 other study(ies) available for atorvastatin and Body Weight
| Article | Year |
|---|---|
A novel class of α-glucosidase and HMG-CoA reductase inhibitors from Ganoderma leucocontextum and the anti-diabetic properties of ganomycin I in KK-A
Topics: Adipose Tissue; Alanine Transaminase; alpha-Glucosidases; Animals; Aspartate Aminotransferases; Blood Glucose; Body Weight; Female; Ganoderma; Glycogen; Glycoside Hydrolase Inhibitors; Hydroquinones; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin Resistance; Kinetics; Liver; Male; Mice; Molecular Docking Simulation; Protein Conformation | 2017 |
Atorvastatin Ester Regulates Lipid Metabolism in Hyperlipidemia Rats via the PPAR-signaling Pathway and HMGCR Expression in the Liver.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Body Weight; Diet, High-Fat; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipid Metabolism; Liver; Male; PPAR gamma; Rats, Sprague-Dawley; Signal Transduction | 2021 |
The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria.
Topics: Animals; Antioxidants; Atorvastatin; Body Weight; Creatinine; Ethylene Glycol; Humans; Hyperoxaluria; Kidney; Male; Oxalates; Polysaccharides; Rats; Rats, Wistar; Ulva; Urea; Uric Acid; Weight Loss | 2023 |
Features of Myocardial Remodeling and Changes in the Blood Lipid Spectrum in Experimental Doxorubicin-Induced Cardiomyopathy and Atorvastatin Administration.
Topics: Animals; Antibiotics, Antineoplastic; Anticholesteremic Agents; Atorvastatin; Atrial Remodeling; Body Weight; Cardiomyopathies; Cholesterol; Doxorubicin; Dyslipidemias; Female; Lipoproteins, VLDL; Myocytes, Cardiac; Organ Size; Rats; Rats, Wistar; Triglycerides | 2020 |
Effect of Nigella sativa, atorvastatin, or L-Carnitine on high fat diet-induced obesity in adult male Albino rats.
Topics: Animals; Anti-Obesity Agents; Atherosclerosis; Atorvastatin; Blood Glucose; Body Weight; Carnitine; Diet, High-Fat; Fatty Liver; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nigella sativa; Obesity; Plant Extracts; Rats; Rats, Wistar | 2021 |
Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 Activation.
Topics: Animals; Antioxidants; Atorvastatin; Body Weight; Cognition; Cognitive Dysfunction; Diet, High-Fat; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice, Inbred C57BL; Obesity; Oxidative Stress; Sirtuin 1 | 2019 |
Low-dose combination of alendronate and atorvastatin reduces ligature-induced alveolar bone loss in rats.
Topics: Acid Phosphatase; Alanine Transaminase; Alendronate; Alkaline Phosphatase; Alveolar Bone Loss; Animals; Aspartate Aminotransferases; Atorvastatin; Body Weight; Bone Density Conservation Agents; Dental Cementum; Gingiva; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Parenteral; Injections, Subcutaneous; Isoenzymes; Leukocyte Disorders; Leukocytes; Leukocytosis; Male; Monocytes; Neutrophils; Peroxidase; Pyrroles; Rats, Wistar; Root Resorption; Tartrate-Resistant Acid Phosphatase | 2014 |
Chronic pravastatin but not atorvastatin treatment impairs cognitive function in two rodent models of learning and memory.
Topics: Animals; Atorvastatin; Body Weight; Cholesterol; Cognition; Discrimination, Psychological; Heptanoic Acids; Male; Memory; Pravastatin; Pyrroles; Rats; Reversal Learning; Time Factors | 2013 |
Antifibrotic effect of atorvastatin on paraquat-induced pulmonary fibrosis: role of PPARγ receptors.
Topics: Anilides; Animals; Atorvastatin; Body Weight; Heptanoic Acids; Herbicides; Hydroxyproline; Lung; Male; Organ Size; Paraquat; Pioglitazone; PPAR gamma; Protective Agents; Pulmonary Fibrosis; Pyrroles; Rats; Rats, Wistar; RNA, Messenger; Thiazolidinediones; Transforming Growth Factor beta1 | 2013 |
Endothelial relaxation mechanisms and oxidative stress are restored by atorvastatin therapy in ovariectomized rats.
Topics: Acetylcholine; Animals; Atorvastatin; Biological Factors; Blotting, Western; Body Weight; Cholesterol; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Heptanoic Acids; Mesenteric Arteries; NADPH Oxidases; Nitric Oxide Synthase; Organ Size; Ovariectomy; Oxidative Stress; Prostaglandins; Pyrroles; Rats, Wistar; Reactive Oxygen Species; Uterus; Vasodilation | 2013 |
Atorvastatin attenuates bleomycin-induced pulmonary fibrosis via suppressing iNOS expression and the CTGF (CCN2)/ERK signaling pathway.
Topics: Animals; Atorvastatin; Bleomycin; Body Weight; Collagen; Connective Tissue Growth Factor; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Pulmonary Fibrosis; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension.
Topics: Animals; Aorta; Atorvastatin; Blood Pressure; Body Weight; Disease Models, Animal; Drug Therapy, Combination; Heptanoic Acids; Hypertension, Renovascular; Male; Nitric Oxide; Piperazines; Purines; Pyrroles; Rats; Rats, Wistar; Sildenafil Citrate; Sulfonamides | 2013 |
Atorvastatin inhibits hyperglycemia-induced expression of osteopontin in the diabetic rat kidney via the p38 MAPK pathway.
Topics: Animals; Atorvastatin; Blood Glucose; Body Weight; Diabetic Nephropathies; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Kidney Glomerulus; Kidney Tubules; Lipids; Male; MAP Kinase Signaling System; Osteopontin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrroles; Rats | 2014 |
Long-term atorvastatin improves age-related endothelial dysfunction by ameliorating oxidative stress and normalizing eNOS/iNOS imbalance in rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Atorvastatin; Body Weight; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Pyrroles; Rats, Wistar; Sirtuin 1 | 2014 |
Atorvastatin prevents type 2 diabetes mellitus--an experimental study.
Topics: Animals; Atorvastatin; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Lipid Metabolism; Male; Pyrroles; Rats; Rats, Wistar; Triglycerides | 2014 |
Comparison of the effects of escitalopram and atorvastatin on diet-induced atherosclerosis in rats.
Topics: Animals; Aorta, Abdominal; Atherosclerosis; Atorvastatin; Body Weight; Citalopram; Diet, High-Fat; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Pyrroles; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Vascular Cell Adhesion Molecule-1 | 2014 |
Prevention of arterial stiffening by using low-dose atorvastatin in diabetes is associated with decreased malondialdehyde.
Topics: Animals; Arginine; Atorvastatin; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fatty Acids; Glycation End Products, Advanced; Hemodynamics; Heptanoic Acids; Lysine; Male; Malondialdehyde; Organ Size; Pyrroles; Rats, Wistar; Streptozocin; Vascular Stiffness | 2014 |
Berberine combined with atorvastatin downregulates LOX‑1 expression through the ET‑1 receptor in monocyte/macrophages.
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Berberine; Body Weight; Cells, Cultured; Cholesterol; Diet, High-Fat; Dietary Fats; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation; Heptanoic Acids; Macrophages; Male; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; RNA, Small Interfering; Scavenger Receptors, Class E; Signal Transduction; Triglycerides | 2014 |
Atorvastatin-mediated protection of the retina in a model of diabetes with hyperlipidemia.
Topics: Animals; Antioxidants; Atorvastatin; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diet, Atherogenic; Heptanoic Acids; Hyperlipidemias; Insulin Resistance; Lipid Metabolism; Male; Oxidative Stress; Proteasome Endopeptidase Complex; Pyrroles; Rats; Reactive Oxygen Species; Retina; Ubiquitin | 2014 |
Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis.
Topics: Animals; Atorvastatin; Body Weight; Cytokines; Diet, High-Fat; Disease Models, Animal; Fatty Acids, Omega-3; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Insulin Resistance; Lipids; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats, Wistar; Sucrose | 2015 |
The hepatoprotective effect of the combination use of Fructus Schisandrae with statin--A preclinical evaluation.
Topics: Adipose Tissue; Animals; Atorvastatin; Body Weight; Cholesterol; Diet, High-Fat; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fatty Liver; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipid Metabolism; Liver; Male; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Schisandra | 2016 |
Treatment with atorvastatin attenuates progression of insulin resistance and pancreatic fibrosis in the Otsuka Long-Evans Tokushima fatty rats.
Topics: Animals; Antioxidants; Apoptosis; Atorvastatin; Body Weight; Eating; Fibrosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin Resistance; Male; Oxidative Stress; Pancreas; Rats; Rats, Inbred OLETF; Transforming Growth Factor beta1 | 2016 |
Postprandial Hypertriglyceridemia Predicts Development of Insulin Resistance Glucose Intolerance and Type 2 Diabetes.
Topics: Animals; Atorvastatin; Blood Glucose; Body Weight; Causality; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Sucrose; Disease Progression; Glucose Intolerance; Glucose Tolerance Test; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Intra-Abdominal Fat; Lipids; Liver; Male; Pancreas; Pioglitazone; Postprandial Period; Prediabetic State; Random Allocation; Rats; Rats, Wistar; Thiazolidinediones | 2016 |
Rosuvastatin safety: An experimental study of myotoxic effects and mitochondrial alterations in rats.
Topics: Animals; Atorvastatin; Body Weight; Creatine Kinase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mitochondria, Muscle; Motor Activity; Muscle, Skeletal; Muscular Diseases; Myoglobin; Organ Size; Rats, Sprague-Dawley; Rosuvastatin Calcium; Rotarod Performance Test | 2017 |
Improvement in erectile function in a rat model of high cholesterol diet-induced atherosclerosis by atorvastatin in a manner that is independent of its lipid-lowering property.
Topics: Animals; Aorta, Abdominal; Atherosclerosis; Atorvastatin; Body Weight; Drug Evaluation, Preclinical; Endothelium, Vascular; Erectile Dysfunction; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Penis; Rats, Sprague-Dawley; Superoxide Dismutase | 2017 |
Celecoxib but not the combination of celecoxib+atorvastatin prevents the development of monocrotaline-induced pulmonary hypertension in the rat.
Topics: Acetylcholine; Animals; Atorvastatin; Blotting, Western; Body Weight; Caspase 3; Celecoxib; Cyclooxygenase Inhibitors; Disease Progression; Drug Combinations; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Nitric Oxide Synthase Type III; Pulmonary Artery; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfonamides; Survival Analysis; Vasodilator Agents | 2008 |
The effect of exogenous cholesterol and lipid-modulating agents on enterocytic amyloid-beta abundance.
Topics: Amyloid beta-Peptides; Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Body Weight; Cholesterol; Cholesterol, Dietary; Enterocytes; Ezetimibe; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Intestinal Absorption; Mice; Mice, Inbred C57BL; Pyrroles; Random Allocation; Triglycerides | 2009 |
Eugenosedin-A prevents hyperglycaemia, hyperlipidaemia and lipid peroxidation in C57BL/6J mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Atorvastatin; Blood Glucose; Body Weight; Brain; Dietary Fats; Female; Glutathione Peroxidase; Heptanoic Acids; Hyperglycemia; Hyperlipidemias; Insulin; Ketanserin; Lipid Peroxidation; Lipogenesis; Liver; Malondialdehyde; Mice; Mice, Inbred C57BL; Piperazines; PPAR gamma; Prazosin; Propranolol; Pyrroles; Superoxide Dismutase; Weight Gain | 2009 |
Effect of atorvastatin on cardiac remodelling and mortality in rats following hyperglycemia and myocardial infarction.
Topics: Animals; Atorvastatin; Body Weight; Cardiac Volume; Collagen Type I; Collagen Type III; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Fibrosis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Myocardial Infarction; Myocardium; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2010 |
Effects of atorvastatin on the regeneration of pancreatic {beta}-cells after streptozotocin treatment in the neonatal rodent.
Topics: Animals; Animals, Newborn; Atorvastatin; Body Weight; Diabetes Mellitus, Experimental; Female; Glucose Tolerance Test; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Male; Neovascularization, Physiologic; Organ Size; Pregnancy; Pyrroles; Rats; Rats, Wistar | 2010 |
Comparative neuroprotective profile of statins in quinolinic acid induced neurotoxicity in rats.
Topics: Analysis of Variance; Animals; Atorvastatin; Behavior, Animal; Body Weight; Corpus Striatum; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lipid Peroxidation; Male; Mitochondria; Motor Activity; Neuroprotective Agents; Neurotoxicity Syndromes; Nitrites; Oxidative Stress; Pyrroles; Quinolinic Acid; Rats; Rats, Wistar; Rotarod Performance Test; Simvastatin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2011 |
Atorvastatin attenuates inflammatory infiltration and vascular remodeling in lung of hypercholesterolemia rabbits.
Topics: Animals; Atorvastatin; Body Weight; Bronchoalveolar Lavage Fluid; Cell Proliferation; Drug Evaluation, Preclinical; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Interleukin-6; Lipids; Lung; Lung Diseases; Macrophages, Alveolar; Male; NF-kappa B; Proliferating Cell Nuclear Antigen; Pulmonary Artery; Pyrroles; Rabbits; Random Allocation | 2010 |
Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Atorvastatin; Body Weight; Brain; Cognition Disorders; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Maze Learning; Mice; Mice, Transgenic; Neuroprotective Agents; Organ Size; Phosphorylation; Plaque, Amyloid; Protein Processing, Post-Translational; Pyrroles; Quinolines; tau Proteins | 2011 |
Metformin and atorvastatin combination further protect the liver in type 2 diabetes with hyperlipidaemia.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Body Weight; C-Reactive Protein; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Combinations; Fatty Liver; Heptanoic Acids; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Interleukin-6; Liver; Metformin; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Pyrroles; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 2011 |
Simultaneous intake of oat bran and atorvastatin reduces their efficacy to lower lipid levels and atherosclerosis in LDLr-/- mice.
Topics: Adipose Tissue; Animals; Anticholesteremic Agents; Aorta; Atherosclerosis; Atorvastatin; Avena; beta-Glucans; Blood; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Dietary Fiber; Eating; Female; Heptanoic Acids; Intestinal Absorption; Lipids; Liver; Mice; Mice, Inbred Strains; Mice, Knockout; Plaque, Atherosclerotic; Pyrroles; Receptors, LDL; Treatment Outcome; Triglycerides | 2011 |
Combined atorvastatin and coenzyme Q10 improve the left ventricular function in isoproterenol-induced heart failure in rat.
Topics: Animals; Atorvastatin; Body Weight; Drug Interactions; Heart Failure; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoproterenol; Male; Myocardium; Organ Size; Pyrroles; Rats; Rats, Wistar; Ubiquinone; Ventricular Dysfunction, Left | 2011 |
Reduction of cerebral infarction in stroke-prone spontaneously hypertensive rats by statins associated with amelioration of oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Atorvastatin; Blood Pressure; Body Weight; Deoxyguanosine; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Infarction, Middle Cerebral Artery; Lipids; Lysine; Oxidative Stress; Pyrroles; Quinolines; Rats; Rats, Inbred SHR; Simvastatin; Survival Analysis | 2005 |
Atorvastatin induces insulin sensitization in Zucker lean and fatty rats.
Topics: Adipose Tissue; Animals; Atorvastatin; Blotting, Western; Body Weight; Diabetes Mellitus, Type 2; Follow-Up Studies; Glucose; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Phosphorylation; Pyrroles; Rats; Rats, Zucker | 2006 |
Effect of atorvastatin on tumor necrosis factor alpha serum concentration and mRNA expression of adipose in hypercholesterolemic rabbits.
Topics: Adipose Tissue; Animals; Anticholesteremic Agents; Atorvastatin; Body Weight; Cholesterol; Cholesterol, LDL; Disease Models, Animal; Heptanoic Acids; Hypercholesterolemia; Male; Pyrroles; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
HMG-CoA reductase inhibitors do not improve glucose intolerance in spontaneously diabetic Goto-Kakizaki rats.
Topics: Animals; Atorvastatin; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus; Glucose Intolerance; Glucose Tolerance Test; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Male; Pravastatin; Pyrroles; Rats; Rats, Wistar; Simvastatin | 2005 |
Effects of atorvastatin on lipid metabolism in normolipidemic and hereditary hyperlipidemic, non-laying hens.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Body Weight; Chickens; Cholesterol; Down-Regulation; Female; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipid Metabolism; Liver; Organ Size; Point Mutation; Pyrroles; Receptors, LDL; RNA, Messenger; Triglycerides | 2006 |
Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats.
Topics: Adenosine Triphosphatases; Animals; Atorvastatin; Body Weight; Catalase; Glutathione; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction; Myocardium; Necrosis; Organ Size; Pyrroles; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2006 |
Atorvastatin prevented and partially reversed adrenocorticotropic hormone-induced hypertension in the rat.
Topics: Adrenocorticotropic Hormone; Animals; Atorvastatin; Blood Pressure; Body Weight; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Nitric Oxide; Pyrroles; Rats; Rats, Sprague-Dawley; Superoxides | 2006 |
Atorvastatin prevented and reversed dexamethasone-induced hypertension in the rat.
Topics: Analysis of Variance; Animals; Atorvastatin; Biomarkers; Blood Pressure; Body Weight; Dexamethasone; Disease Models, Animal; Down-Regulation; Glucocorticoids; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Male; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Organ Size; Pyrroles; Rats; Rats, Sprague-Dawley; Superoxides; Thymus Gland | 2006 |
Effects of chronic treatment with statins and fenofibrate on rat skeletal muscle: a biochemical, histological and electrophysiological study.
Topics: Action Potentials; Animals; Aquaporin 4; Atorvastatin; Body Weight; Chloride Channels; Dose-Response Relationship, Drug; Eating; Fatty Acids, Monounsaturated; Fenofibrate; Fluvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Kidney Diseases; Lipids; Male; Membrane Potentials; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle, Skeletal; Muscular Diseases; Myosin Heavy Chains; Organ Size; Pyrroles; Rats; Rats, Wistar; Rhabdomyolysis; Time Factors | 2006 |
[Metabolic syndrome in men of 35-65 years old from rural district of Poltava region and possibility of the prophylactic therapy with atorvastatine].
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Body Weight; Cardiovascular Diseases; Heptanoic Acids; Humans; Incidence; Lipids; Male; Metabolic Syndrome; Middle Aged; Pyrroles; Rural Health; Rural Population; Ukraine | 2006 |
Reversal of memory deficits by Atorvastatin and Simvastatin in rats.
Topics: Alprazolam; Amnesia; Animals; Atorvastatin; Body Weight; Cholesterol; Dietary Fats; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Maze Learning; Memory; Pyrroles; Rats; Rats, Wistar; Reaction Time; Scopolamine; Simvastatin; Stimulation, Chemical | 2007 |
The cardioprotective effect of a statin and cilostazol combination: relationship to Akt and endothelial nitric oxide synthase activation.
Topics: Adenosine; Administration, Oral; Animals; Atorvastatin; Body Weight; Cilostazol; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Heptanoic Acids; Immunoblotting; Male; Myocardium; Nitric Oxide Synthase Type III; Organ Culture Techniques; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Risk Factors; Tetrazoles; Treatment Outcome | 2007 |
Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.
Topics: Animals; Atorvastatin; Biopterins; Body Weight; Cell Adhesion Molecules; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; GTP Cyclohydrolase; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intramolecular Oxidoreductases; Male; Microfilament Proteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoproteins; Pyrroles; Rats; Rats, Wistar; Stem Cells; Tetrahydrofolate Dehydrogenase; Vasodilation | 2008 |
Anti-inflammatory effects of combined treatment with acetyl salicylic acid and atorvastatin in haemodialysis patients affected by Normal Weight Obese syndrome.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Aspirin; Atorvastatin; Body Fat Distribution; Body Mass Index; Body Weight; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Inflammation; Kidney Failure, Chronic; Lipid Metabolism; Male; Middle Aged; Nutrition Assessment; Obesity; Prealbumin; Pyrroles; Renal Dialysis; Serum Albumin; Syndrome | 2008 |
Combined treatment with atorvastatin and minocycline suppresses severity of EAE.
Topics: Animals; Anti-Bacterial Agents; Atorvastatin; Body Weight; Cell Proliferation; Cytokines; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Female; Glial Fibrillary Acidic Protein; Glycoproteins; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, Inbred C57BL; Minocycline; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neurologic Examination; Peptide Fragments; Pyrroles; Stereotaxic Techniques; T-Lymphocytes; Time Factors | 2008 |
Developmental toxicity of the HMG-CoA reductase inhibitor, atorvastatin, in rats and rabbits.
Topics: Abnormalities, Drug-Induced; Animals; Anticholesteremic Agents; Atorvastatin; Body Weight; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pregnancy; Pyrroles; Rabbits; Rats; Rats, Sprague-Dawley; Toxicity Tests | 1994 |
Pre- and postnatal toxicity of the HMG-CoA reductase inhibitor atorvastatin in rats.
Topics: Animals; Area Under Curve; Atorvastatin; Behavior, Animal; Body Weight; Eating; Female; Fertility; Gastric Mucosa; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactation; Male; Postural Balance; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Pyrroles; Rats; Rats, Sprague-Dawley; Reflex, Startle; Survival Rate; Tissue Distribution | 1998 |
Limitation of heart growth in neonatal piglets by simvastatin and atorvastatin: comparison with pravastatin.
Topics: Administration, Oral; Animals; Animals, Newborn; Atorvastatin; Blood Pressure; Body Weight; DNA; Heart; Heart Rate; Heart Ventricles; Heptanoic Acids; Mitogen-Activated Protein Kinases; Myocardium; Organ Size; Pravastatin; Proteins; Pyrroles; RNA; Simvastatin; Swine; Water | 2001 |