Page last updated: 2024-08-24

atorvastatin and Blood Poisoning

atorvastatin has been researched along with Blood Poisoning in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (21.05)29.6817
2010's14 (73.68)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Ge, X; Shi, M; Tai, Y; Tian, J; Xu, W; Zhao, C; Zhu, G1
Chang, SS; Hsu, TC; Lee, CC; Lee, M; Lee, MG; Porta, L; Tsai, KC; Yo, CH1
Chu, Y; Ding, M; Ma, H; Ren, H; Wang, C; Xu, Q; Yao, Q; Zuo, G1
McAuley, DF; O'Kane, CM; Perkins, GD1
Boobalan, R; Choudhury, S; Kandasamy, K; Mishra, SK; Parida, S; Reddy, N; Singh, TU; Singh, V; Sukumarn, SV; Thangamalai, R1
Coldewey, SM; Thiemermann, C1
Choudhury, S; Darzi, SA; Dash, JR; Debroy, B; Kannan, K; Mishra, SK; Parida, S; Paul, A; Pule Addison, M; Singh, TU; Singh, V; Thangamalai, R1
Addison, MP; Choudhury, S; Darzi, SA; Dash, JR; Kandasamy, K; Kasa, JK; Maruti, BS; Mishra, SK; Parida, S; Singh, TU; Singh, V1
Lee, CR; Zeldin, DC1
Freir, NM; Jones, M; Kruger, PS; Roberts, MS; Robertson, TA; Venkatesh, B1
Falagas, ME; Kopterides, P1
Kathirvel, K; Kuntamallappanavar, G; Leo, MD; Mishra, SK; Subramani, J; Uttam Singh, T1
Bagshaw, SM; Bellomo, R; Cruz, DN; Gibney, N; Haase, M; Honore, PM; Joannes-Boyau, O; McAlister, FA; Palevsky, PM; Prowle, J; Ronco, C1
Harward, ML; Jones, MA; Joyce, CJ; Kostner, KM; Kruger, PS; Roberts, MS; Venkatesh, B1
Calisto, KL; Camacho, AC; Carvalheira, JB; Carvalho, Bde M; Guadagnini, D; Mittestainer, FC; Ropelle, ER; Saad, MJ1
Ahanger, AA; Choudhury, S; Kandasamy, K; Mishra, SK; More, AS; Parida, S; Prawez, S; Singh, TU1
Barnett, AH; Cooke, MW; Gao, F; Hawkey, P; Hong, T; Jones, A; Linhartova, L; Melody, T; Patel, JM; Perkins, GD; Snaith, C; Thickett, DR1
Bailey, M; Bellomo, R; Cooper, DJ; Harward, M; Higgins, A; Howe, B; Jones, D; Joyce, C; Kostner, K; Kruger, P; McNeil, J; Nichol, A; Roberts, MS; Syres, G; Venkatesh, B1
Kruger, PS1

Reviews

1 review(s) available for atorvastatin and Blood Poisoning

ArticleYear
Statins for sepsis: a critical and updated review.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2009, Volume: 15, Issue:4

    Topics: Anticholesteremic Agents; Atorvastatin; Bacterial Infections; Heptanoic Acids; Humans; Pyrroles; Sepsis; Simvastatin; Treatment Outcome

2009

Trials

3 trial(s) available for atorvastatin and Blood Poisoning

ArticleYear
Continuation of statin therapy in patients with presumed infection: a randomized controlled trial.
    American journal of respiratory and critical care medicine, 2011, Mar-15, Volume: 183, Issue:6

    Topics: Aged; Aged, 80 and over; Atorvastatin; C-Reactive Protein; Cholesterol; Disease Progression; Double-Blind Method; Drug Administration Schedule; Female; Heptanoic Acids; Hospital Mortality; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Interleukin-6; Male; Middle Aged; Prospective Studies; Pyrroles; Sepsis; Severity of Illness Index; Treatment Outcome

2011
Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial).
    Critical care (London, England), 2012, Dec-11, Volume: 16, Issue:6

    Topics: Anti-Inflammatory Agents; Atorvastatin; Disease Progression; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Length of Stay; Male; Middle Aged; Patient Readmission; Pyrroles; Sepsis; Severity of Illness Index; Treatment Outcome

2012
A multicenter randomized trial of atorvastatin therapy in intensive care patients with severe sepsis.
    American journal of respiratory and critical care medicine, 2013, Apr-01, Volume: 187, Issue:7

    Topics: Aged; Atorvastatin; C-Reactive Protein; Critical Illness; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intensive Care Units; Interleukin-6; Length of Stay; Lipids; Male; Middle Aged; Prospective Studies; Pyrroles; Sepsis

2013

Other Studies

15 other study(ies) available for atorvastatin and Blood Poisoning

ArticleYear
Atorvastatin Relieves Cognitive Disorder After Sepsis Through Reverting Inflammatory Cytokines, Oxidative Stress, and Neuronal Apoptosis in Hippocampus.
    Cellular and molecular neurobiology, 2020, Volume: 40, Issue:4

    Topics: Animals; Anxiety; Apoptosis; Astrocytes; Atorvastatin; Behavior, Animal; Cecum; Cognition Disorders; Cytokines; Glial Fibrillary Acidic Protein; Hippocampus; Inflammation Mediators; Learning; Ligation; Male; Memory Disorders; Mice, Inbred ICR; Morris Water Maze Test; Motor Activity; Neurons; Oxidative Stress; Punctures; Sepsis; Survival Analysis

2020
A Population-Based Cohort Study on the Drug-Specific Effect of Statins on Sepsis Outcome.
    Chest, 2018, Volume: 153, Issue:4

    Topics: Aged; Anti-Infective Agents; Atorvastatin; Cohort Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Respiratory Insufficiency; Rosuvastatin Calcium; Sepsis; Simvastatin; Taiwan; Treatment Outcome

2018
[Protective effects of combined use of atorvastatin and low molecular weight heparin on the inflammatory reaction and pulmonary functions in rats with sepsis].
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:5

    Topics: Animals; Atorvastatin; Cytokines; Disease Models, Animal; Heparin, Low-Molecular-Weight; HMGB1 Protein; Inflammation; Interleukin-1beta; Interleukin-6; Lung; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis; Tumor Necrosis Factor-alpha

2016
Statins and sepsis: potential benefit but more unanswered questions.
    American journal of respiratory and critical care medicine, 2013, Apr-01, Volume: 187, Issue:7

    Topics: Atorvastatin; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Male; Pyrroles; Sepsis

2013
Atorvastatin prevents sepsis-induced downregulation of myocardial β1-adrenoceptors and decreased cAMP response in mice.
    Shock (Augusta, Ga.), 2014, Volume: 41, Issue:5

    Topics: Animals; Atorvastatin; Blotting, Western; Catecholamines; Cyclic AMP; Heptanoic Acids; Lactic Acid; Male; Mice; Myocardium; Pyrroles; Real-Time Polymerase Chain Reaction; Receptors, Adrenergic, beta; Sepsis; Ventricular Function, Left

2014
Pleiotropic effects of atorvastatin in experimental sepsis: preservation of β1-adrenoreceptor signaling in the heart.
    Shock (Augusta, Ga.), 2014, Volume: 41, Issue:5

    Topics: Animals; Atorvastatin; Cyclic AMP; Heptanoic Acids; Male; Myocardium; Pyrroles; Receptors, Adrenergic, beta; Sepsis

2014
Combined treatment with atorvastatin and imipenem improves survival and vascular functions in mouse model of sepsis.
    Vascular pharmacology, 2015, Volume: 71

    Topics: Animals; Anti-Bacterial Agents; Atorvastatin; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipenem; Male; Mice; Organ Culture Techniques; Sepsis; Survival Rate

2015
Atorvastatin along with imipenem attenuates acute lung injury in sepsis through decrease in inflammatory mediators and bacterial load.
    European journal of pharmacology, 2015, Oct-15, Volume: 765

    Topics: Acute Lung Injury; Animals; Atorvastatin; Bacterial Load; Drug Therapy, Combination; Imipenem; Inflammation Mediators; Male; Mice; Sepsis

2015
Resolvin Infectious Inflammation by Targeting the Host Response.
    The New England journal of medicine, 2015, Nov-26, Volume: 373, Issue:22

    Topics: Animals; Atorvastatin; Cells, Cultured; Disease Models, Animal; Docosahexaenoic Acids; Endothelial Cells; Escherichia coli Infections; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Mice; Neutrophils; Phagocytosis; Sepsis

2015
A preliminary study of atorvastatin plasma concentrations in critically ill patients with sepsis.
    Intensive care medicine, 2009, Volume: 35, Issue:4

    Topics: Aged; Anticholesteremic Agents; APACHE; Atorvastatin; Chromatography, High Pressure Liquid; Critical Care; Female; Heptanoic Acids; Humans; Male; Prospective Studies; Pyrroles; Sepsis

2009
Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis.
    Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:6

    Topics: Acetylcholine; Animals; Aorta; Atorvastatin; Biological Factors; Blood Cell Count; Blood Pressure; Calcium Channel Blockers; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypotension; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Phenylephrine; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Sepsis; Vasodilation

2009
Recent trials in critical care nephrology.
    Contributions to nephrology, 2010, Volume: 165

    Topics: Acute Kidney Injury; Atorvastatin; Critical Care; Critical Illness; Decision Support Systems, Clinical; Evidence-Based Medicine; Female; Hemofiltration; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Length of Stay; Male; Metabolic Clearance Rate; Middle Aged; Multicenter Studies as Topic; Pyrroles; Random Allocation; Randomized Controlled Trials as Topic; Renal Circulation; Renal Dialysis; Renal Replacement Therapy; Sepsis; Severity of Illness Index; Survival Rate

2010
Atorvastatin improves survival in septic rats: effect on tissue inflammatory pathway and on insulin signaling.
    PloS one, 2010, Dec-06, Volume: 5, Issue:12

    Topics: Adipose Tissue; Animals; Atorvastatin; Glucose; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Insulin; Interleukin-6; Liver; Male; Muscles; Pyrroles; Rats; Rats, Wistar; Sepsis; Signal Transduction; Tumor Necrosis Factor-alpha

2010
Atorvastatin prevents vascular hyporeactivity to norepinephrine in sepsis: role of nitric oxide and α₁-adrenoceptor mRNA expression.
    Shock (Augusta, Ga.), 2011, Volume: 36, Issue:1

    Topics: Animals; Atorvastatin; Enzyme Inhibitors; Guanylate Cyclase; Heptanoic Acids; Mice; Nitric Oxide; Norepinephrine; Oxadiazoles; Polymerase Chain Reaction; Pyrroles; Quinoxalines; Receptors, Adrenergic, alpha-1; RNA, Messenger; Sepsis; Vasoconstrictor Agents

2011
Re: Statins and sepsis.
    British journal of anaesthesia, 2008, Volume: 100, Issue:6

    Topics: Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Randomized Controlled Trials as Topic; Sepsis

2008