Compounds > atorvastatin
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atorvastatin and Aortic Valve Stenosis

atorvastatin has been researched along with Aortic Valve Stenosis in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (73.91)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aibibula, A; Shabiti, A; Tuerxun, A; Wufuer, H1
Baldascino, F; Cabaro, S; Caruso, A; D'Esposito, V; Davin, L; De Bellis, A; Ferrara, N; Ferro, A; Formisano, P; Formisano, R; Grimaldi, MG; Lancellotti, P; Leosco, D; Paolillo, S; Parisi, V; Perrone Filardi, P; Petraglia, L; Rengo, G; Vitale, D1
Dadjou, Y; Panahi, Y; Pishgoo, B; Rakhshankhah, AS; Sahebkar, A; Taghipour, HR1
Amarenco, P; Arsenault, BJ; Bao, W; Barter, P; Boekholdt, SM; DeMicco, DA; Mora, S; Pedersen, T; Tardif, JC; Waters, DD1
Rajamannan, NM2
Cawley, PJ; Otto, CM1
Alber, HF; Bartel, T; Dichtl, W; Feuchtner, GM; Grander, W; Hintringer, F; Müller, S; Pachinger, O; Reinthaler, M; Süssenbacher, A; Ulmer, H1
Pedersen, TR1
Jin, H; Li, ZG; Xu, ZY; Yao, F1
Dimitrow, PP; Gackowski, A; Jawień, M1
Antonini-Canterin, F; Cervesato, E; Granata, G; Nicolosi, GL; Pavan, D; Piazza, R; Popescu, BA; Zuppiroli, A1
Bloomfield, P; Boon, NA; Cowell, SJ; Newby, DE; Northridge, DB; Prescott, RJ; Reid, J1
Rosenhek, R1
Caira, F; Rajamannan, NM; Spelsberg, TC; Stock, SR; Subramaniam, M1
Pai, RG1
Boon, NA; Burton, J; Cowell, SJ; Houslay, ES; Newby, DE; Northridge, DB; Prescott, RJ; Reid, J1
Amrani, M; Chester, AH; Osman, L; Smolenski, RT; Yacoub, MH1
Amrani, M; Chester, AH; Latif, N; Osman, L; Yacoub, MH1
Hashemi, MJ; Hekmat, M; Kouhi, A; Mojtahedzadeh, S; Naderi, N; Nobahar, R; Rafeiyian, S1
Bonnaire, B; Bugnicourt, JM; Garcia, PY; Godefroy, O; Lefranc, M; Lepage, L1
Griffin, BP; Lauer, MS; Novaro, GM; Pearce, GL; Sprecher, DL; Tiong, IY1

Reviews

2 review(s) available for atorvastatin and Aortic Valve Stenosis

ArticleYear
Prevention of calcific aortic valve stenosis-fact or fiction?
    Annals of medicine, 2009, Volume: 41, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Stenosis; Atherosclerosis; Atorvastatin; Calcinosis; Cardiomyopathies; Disease Progression; Endothelium, Vascular; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Randomized Controlled Trials as Topic; Renin-Angiotensin System

2009
Statins and aortic stenosis progression: are biologic targets still an option?
    Current cardiology reports, 2005, Volume: 7, Issue:6

    Topics: Aortic Valve Stenosis; Atorvastatin; Disease Progression; Echocardiography, Doppler; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pyrroles

2005

Trials

6 trial(s) available for atorvastatin and Aortic Valve Stenosis

ArticleYear
Atorvastatin therapy is not associated with slowing the progression of aortic stenosis: findings of a randomized controlled trial.
    Clinical laboratory, 2013, Volume: 59, Issue:3-4

    Topics: Aged; Aortic Valve Stenosis; Atorvastatin; Disease Progression; Double-Blind Method; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Pyrroles

2013
Impact of high-dose atorvastatin therapy and clinical risk factors on incident aortic valve stenosis in patients with cardiovascular disease (from TNT, IDEAL, and SPARCL).
    The American journal of cardiology, 2014, Apr-15, Volume: 113, Issue:8

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anticholesteremic Agents; Aortic Valve Stenosis; Atorvastatin; Cholesterol; Coronary Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Global Health; Heptanoic Acids; Humans; Incidence; Male; Middle Aged; Prognosis; Pyrroles; Risk Factors; Time Factors

2014
Prognosis and risk factors in patients with asymptomatic aortic stenosis and their modulation by atorvastatin (20 mg).
    The American journal of cardiology, 2008, Sep-15, Volume: 102, Issue:6

    Topics: Aged; Aortic Valve; Aortic Valve Stenosis; Atorvastatin; C-Reactive Protein; Calcinosis; Cholesterol; Disease Progression; Female; Heart Valve Prosthesis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Multivariate Analysis; Natriuretic Peptide, Brain; Peptide Fragments; Prognosis; Prospective Studies; Pyrroles; Risk Factors; Tomography, X-Ray Computed

2008
The influence of statins on levels of calcification biomarkers in patients with aortic sclerosis or mild aortic stenosis.
    The Journal of heart valve disease, 2011, Volume: 20, Issue:1

    Topics: Aged; Aortic Valve Stenosis; Atorvastatin; Biomarkers; Calcinosis; Down-Regulation; Drug Administration Schedule; Echocardiography, Doppler; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Osteopontin; Osteoprotegerin; Poland; Pyrroles; RANK Ligand; Sclerosis; Severity of Illness Index; Time Factors; Treatment Outcome

2011
A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis.
    The New England journal of medicine, 2005, Jun-09, Volume: 352, Issue:23

    Topics: Anticholesteremic Agents; Aortic Valve; Aortic Valve Stenosis; Atorvastatin; Blood Flow Velocity; Calcinosis; Cholesterol, LDL; Disease Progression; Double-Blind Method; Echocardiography, Doppler; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Treatment Failure

2005
Progressive coronary calcification despite intensive lipid-lowering treatment: a randomised controlled trial.
    Heart (British Cardiac Society), 2006, Volume: 92, Issue:9

    Topics: Adult; Aged; Aortic Valve Stenosis; Atorvastatin; Calcinosis; Coronary Artery Disease; Disease Progression; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrroles; Tomography, Spiral Computed; Treatment Failure

2006

Other Studies

15 other study(ies) available for atorvastatin and Aortic Valve Stenosis

ArticleYear
Therapeutic Effect and Mechanism of Action of Abnormal Savda Munziq in Development of Degenerative Atherosclerotic Aortic Valve Disease.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Sep-14, Volume: 23

    Topics: Animals; Aortic Valve; Aortic Valve Stenosis; Atherosclerosis; Atorvastatin; Bicuspid Aortic Valve Disease; Calcinosis; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Diet, High-Fat; Drugs, Chinese Herbal; Heart Defects, Congenital; Heart Valve Diseases; Male; Medicine, Traditional; Plant Extracts; Rabbits; Triglycerides

2017
Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue.
    International journal of cardiology, 2019, Jan-01, Volume: 274

    Topics: Adipose Tissue; Aged; Aortic Valve; Aortic Valve Stenosis; Atorvastatin; Biopsy; Calcinosis; Coronary Artery Disease; Cytokines; Echocardiography; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Pericardium; Retrospective Studies

2019
Atorvastatin Attenuates Bone Loss and Aortic Valve Atheroma in LDLR Mice.
    Cardiology, 2015, Volume: 132, Issue:1

    Topics: Animals; Anticholesteremic Agents; Aortic Valve; Aortic Valve Stenosis; Atherosclerosis; Atorvastatin; Calcinosis; Cholesterol, Dietary; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Macrophages; Mice; Osteogenesis; Osteoporosis; Plaque, Atherosclerotic; X-Ray Microtomography

2015
Intensive lipid-lowering therapy for patients with aortic stenosis.
    The American journal of cardiology, 2008, Dec-01, Volume: 102, Issue:11

    Topics: Aortic Valve Stenosis; Atorvastatin; Clinical Trials as Topic; Disease Progression; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2008
Aortic and mitral valve replacement with reconstruction of the intervalvular fibrous body in familial hypercholesterolemia.
    The Thoracic and cardiovascular surgeon, 2009, Volume: 57, Issue:5

    Topics: Aortic Valve Stenosis; Atorvastatin; Blood Component Removal; Female; Heart Valve Prosthesis Implantation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Mitral Valve Insufficiency; Pyrroles; Treatment Outcome; Xanthomatosis; Young Adult

2009
Effect of statins on the progression of bioprosthetic aortic valve degeneration.
    The American journal of cardiology, 2003, Dec-15, Volume: 92, Issue:12

    Topics: Aged; Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Stenosis; Atorvastatin; Bioprosthesis; Coronary Artery Bypass; Coronary Artery Disease; Female; Heart Valve Prosthesis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Pravastatin; Prosthesis Failure; Pyrroles; Retrospective Studies; Simvastatin; Treatment Outcome; Ultrasonography

2003
Is it time for medical therapy for aortic valve disease?
    Expert review of cardiovascular therapy, 2004, Volume: 2, Issue:6

    Topics: Aged; Aged, 80 and over; Animals; Aortic Valve Stenosis; Atorvastatin; Biopsy, Needle; Calcinosis; Controlled Clinical Trials as Topic; Disease Models, Animal; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hypolipidemic Agents; Immunohistochemistry; Male; Middle Aged; Practice Guidelines as Topic; Prognosis; Pyrroles; Risk Assessment; Severity of Illness Index; Survival Rate; Treatment Outcome

2004
Statins for aortic stenosis.
    The New England journal of medicine, 2005, Jun-09, Volume: 352, Issue:23

    Topics: Aortic Valve Stenosis; Atorvastatin; Calcinosis; Disease Progression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles

2005
Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp5 receptor pathway.
    Circulation, 2005, Aug-30, Volume: 112, Issue:9 Suppl

    Topics: Animals; Animals, Inbred Strains; Aortic Valve Stenosis; Atorvastatin; beta Catenin; Calcinosis; Cell Division; Cells, Cultured; Cholesterol, Dietary; Diet, Atherogenic; Fibroblasts; Gene Expression Regulation; Heptanoic Acids; Hypercholesterolemia; LDL-Receptor Related Proteins; Lipoproteins, LDL; Low Density Lipoprotein Receptor-Related Protein-5; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Ossification, Heterotopic; Osteopontin; Pyrroles; Rabbits; Sialoglycoproteins; Sus scrofa

2005
Statins don't stop aortic valve narrowing...or memory loss (yet).
    Harvard heart letter : from Harvard Medical School, 2005, Volume: 16, Issue:1

    Topics: Aortic Valve Stenosis; Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Memory Disorders; Pyrroles; Treatment Failure

2005
A novel role of extracellular nucleotides in valve calcification: a potential target for atorvastatin.
    Circulation, 2006, Jul-04, Volume: 114, Issue:1 Suppl

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Aged; Alkaline Phosphatase; Aortic Valve; Aortic Valve Stenosis; Apyrase; Atorvastatin; Biomarkers; Calcinosis; Cell Differentiation; Cells, Cultured; Drug Evaluation, Preclinical; Heptanoic Acids; Humans; Middle Aged; Osteoblasts; Pyrroles; Receptors, Purinergic P2; Second Messenger Systems

2006
Role of human valve interstitial cells in valve calcification and their response to atorvastatin.
    Circulation, 2006, Jul-04, Volume: 114, Issue:1 Suppl

    Topics: Aged; Alkaline Phosphatase; Aortic Valve; Aortic Valve Stenosis; Atorvastatin; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Calcinosis; Cell Differentiation; Cells, Cultured; Connective Tissue Cells; Culture Media; Fibrosis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Osteoblasts; Osteocalcin; Pyrroles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta3

2006
Supravalvular and valvular aortic stenosis in heterozygous familial hypercholesterolemia.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2007, Volume: 16, Issue:4

    Topics: Adolescent; Aortic Stenosis, Supravalvular; Aortic Valve Stenosis; Atorvastatin; Cholestyramine Resin; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Male; Niacin; Pyrroles

2007
[Stroke due to spontaneous calcified cerebral embolus as presenting feature of calcified aortic stenosis].
    Journal des maladies vasculaires, 2008, Volume: 33, Issue:2

    Topics: Aged, 80 and over; Anterior Cerebral Artery; Aortic Valve; Aortic Valve Stenosis; Aspirin; Atorvastatin; Calcinosis; Heptanoic Acids; Humans; Intracranial Embolism; Male; Pyrroles; Stroke; Tomography, X-Ray Computed

2008
Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis.
    Circulation, 2001, Oct-30, Volume: 104, Issue:18

    Topics: Aged; Aortic Valve Stenosis; Atorvastatin; Calcinosis; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; Echocardiography; Electrocardiography; Fatty Acids, Monounsaturated; Female; Fluvastatin; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Male; Multivariate Analysis; Pravastatin; Pyrroles; Retrospective Studies; Risk Factors; Simvastatin; Treatment Outcome; Triglycerides; Vascular Patency

2001