Compounds > atorvastatin
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atorvastatin and Aortic Aneurysm, Abdominal

atorvastatin has been researched along with Aortic Aneurysm, Abdominal in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's9 (64.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, Y; Lu, G; Sun, D; Wang, DW; Yan, J; Zuo, H1
Baxa, J; Boudová, L; Eberlová, L; Houdek, K; Kobr, J; Kočová, J; Křížková, V; Liška, V; Moláček, J; Nedorost, L; Tolinger, P; Tonar, Z; Třeška, V; Witter, K1
Do e, Z; Fukumoto, Y; Kanazawa, M; Matsumoto, Y; Sato, A; Satoh, K; Shimizu, T; Shimokawa, H; Takahashi, K1
Amano, A; Daida, H; Kajimoto, K; Kasai, T; Kojima, Y; Miyauchi, K; Niinami, H; Shimada, A; Shimada, K1
Kitas, GD; Melas, N; Saratzis, A; Saratzis, N1
Abraham, C; Chalifour, LE; Dostanic, S; Mitmaker, B; Obrand, D; Schweitzer, M; Sheiner, N1
Abraham, C; Chalifour, LE; Dostanic, S; Meilleur, M; Mitmaker, B; Obrand, D; Schweitzer, M; Sheiner, N; Sugahara, T1
de Vries, JP; Hoefer, IE; Hurks, R; Kerver, M; Moll, FL; Pasterkamp, G; Schoneveld, A; Tangelder, MJ; Vink, A1
Chetter, IC; Khan, JA; Mazari, FA; McCollum, PT; Mockford, K; Rahman, MN1
Bi, H; Chen, WA; Daugherty, A; Hong, B; Luo, Y; Wang, JA; Wang, Y; Xie, X; Zhang, S1
Baxa, J; Eberlová, L; Houdek, K; Kobr, J; Křížková, V; Moláček, J; Tonar, Z; Třeška, V1
Aronow, WS; Babu, S; Kakar, P; Sandhu, R; Sukhija, R1
Bax, JJ; Boersma, E; Dunkelgrün, M; Feringa, HH; Koning, J; Poldermans, D; Schouten, O; van Laanen, JH; van Urk, H; Vidakovic, R1
Aoki, M; Miyake, T; Morishita, R; Nishimura, M; Ogihara, T; Ohgi, S; Shiraya, S; Yoshikazu, F1

Reviews

1 review(s) available for atorvastatin and Aortic Aneurysm, Abdominal

ArticleYear
Can statins suppress the development of abdominal aortic aneurysms? A review of the current evidence.
    Angiology, 2010, Volume: 61, Issue:2

    Topics: Animals; Aortic Aneurysm, Abdominal; Atorvastatin; Blood Vessels; Cardiovascular Agents; Disease Progression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Matrix Metalloproteinases; Models, Animal; Pyrroles; Risk Assessment; Simvastatin

2010

Trials

2 trial(s) available for atorvastatin and Aortic Aneurysm, Abdominal

ArticleYear
Short-term 20-mg atorvastatin therapy reduces key inflammatory factors including c-Jun N-terminal kinase and dendritic cells and matrix metalloproteinase expression in human abdominal aortic aneurysmal wall.
    Atherosclerosis, 2009, Volume: 206, Issue:2

    Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Atorvastatin; Cell Proliferation; Dendritic Cells; Female; Heptanoic Acids; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinases; Middle Aged; Muscle, Smooth, Vascular; Pyrroles; Tissue Inhibitor of Metalloproteinase-1

2009
A randomized placebo controlled trial of the effect of preoperative statin use on matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in areas of low and peak wall stress in patients undergoing elective open repair of abdominal ao
    Annals of vascular surgery, 2011, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atorvastatin; Chi-Square Distribution; Double-Blind Method; Drug Administration Schedule; Elective Surgical Procedures; England; Female; Finite Element Analysis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 8; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Middle Aged; Placebo Effect; Preoperative Care; Pyrroles; Stress, Mechanical; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Treatment Outcome; Vascular Surgical Procedures

2011

Other Studies

11 other study(ies) available for atorvastatin and Aortic Aneurysm, Abdominal

ArticleYear
Inhibition of endoplasmic reticulum stress signaling pathway: A new mechanism of statins to suppress the development of abdominal aortic aneurysm.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Atorvastatin; Calcium Chloride; Cell Line; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Random Allocation

2017
Focal histopathological progression of porcine experimental abdominal aortic aneurysm is mitigated by atorvastatin.
    International angiology : a journal of the International Union of Angiology, 2013, Volume: 32, Issue:3

    Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atorvastatin; Disease Models, Animal; Disease Progression; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pancreatic Elastase; Pyrroles; Sus scrofa; Time Factors; Ultrasonography

2013
Combination therapy with atorvastatin and amlodipine suppresses angiotensin II-induced aortic aneurysm formation.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Amlodipine; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apoptosis; Atorvastatin; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Drug Therapy, Combination; Enzyme Activation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Pyrroles; rho-Associated Kinases

2013
Atorvastatin mediates increases in intralesional BAX and BAK expression in human end-stage abdominal aortic aneurysms.
    Canadian journal of physiology and pharmacology, 2009, Volume: 87, Issue:11

    Topics: Aged; Aged, 80 and over; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis Regulatory Proteins; Atorvastatin; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase 3; Disease Progression; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Polymorphism, Single Nucleotide; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2009
Atorvastatin modulates matrix metalloproteinase expression, activity, and signaling in abdominal aortic aneurysms.
    Vascular and endovascular surgery, 2010, Volume: 44, Issue:2

    Topics: Aged; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atorvastatin; Down-Regulation; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Matrix Metalloproteinases; Phosphorylation; Pyrroles; Signal Transduction; Smad2 Protein; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta

2010
Different effects of commonly prescribed statins on abdominal aortic aneurysm wall biology.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2010, Volume: 39, Issue:5

    Topics: Aged; Aorta; Aortic Aneurysm, Abdominal; Atorvastatin; Biomarkers; Cathepsin A; Cathepsin B; Chi-Square Distribution; Cohort Studies; Disease Progression; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Interleukins; Lymphotoxin-alpha; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Netherlands; Pravastatin; Pyrroles; Risk Assessment; Risk Factors; Simvastatin; Tumor Necrosis Factor-alpha; Vascular Surgical Procedures

2010
Statins exert differential effects on angiotensin II-induced atherosclerosis, but no benefit for abdominal aortic aneurysms.
    Atherosclerosis, 2011, Volume: 217, Issue:1

    Topics: Angiotensin II; Animal Feed; Animals; Anti-Inflammatory Agents; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Atorvastatin; Blood Pressure; Fluorobenzenes; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides

2011
[Pharmacological influencing of abdominal aortic aneurysm model - animal experimental study, primary results].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 2012, Volume: 91, Issue:9

    Topics: Animals; Aortic Aneurysm, Abdominal; Atorvastatin; Cholinergic Antagonists; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Pyrroles; Sus scrofa

2012
Mortality and size of abdominal aortic aneurysm at long-term follow-up of patients not treated surgically and treated with and without statins.
    The American journal of cardiology, 2006, Jan-15, Volume: 97, Issue:2

    Topics: Aged; Aortic Aneurysm, Abdominal; Atorvastatin; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pyrroles; Simvastatin

2006
Statins are associated with a reduced infrarenal abdominal aortic aneurysm growth.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2006, Volume: 32, Issue:1

    Topics: Aged; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Atorvastatin; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Netherlands; Population Surveillance; Pyrroles; Retrospective Studies; Simvastatin; Time Factors; Ultrasonography

2006
Inhibition of development of experimental aortic abdominal aneurysm in rat model by atorvastatin through inhibition of macrophage migration.
    Atherosclerosis, 2009, Volume: 202, Issue:1

    Topics: Animals; Anticholesteremic Agents; Aortic Aneurysm, Abdominal; Atorvastatin; Cell Movement; Collagen; Disease Models, Animal; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Macrophages; Pancreatic Elastase; Pyrroles; Rats; Rats, Wistar; Treatment Outcome

2009