atorvastatin has been researched along with Alloxan Diabetes in 76 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (19.74) | 29.6817 |
| 2010's | 51 (67.11) | 24.3611 |
| 2020's | 10 (13.16) | 2.80 |
| Authors | Studies |
|---|---|
| Bass, JY; Caravella, JA; Chen, L; Creech, KL; Deaton, DN; Madauss, KP; Marr, HB; McFadyen, RB; Miller, AB; Mills, WY; Navas, F; Parks, DJ; Smalley, TL; Spearing, PK; Todd, D; Williams, SP; Wisely, GB | 1 |
| Mohamad, A; Zahran, F; Zein, N | 1 |
| Abdollahi, A; Akbarian, R; Chamanara, M; Dehpour, AR; Ejtemaei Mehr, S; Rashidian, A | 1 |
| El Medany, AMH; Ghazala, RA; Hammadi, SHM; Khalifa, HM; Zakaria Mohammed, HS | 1 |
| Al Gharram, T; Mayyas, F | 1 |
| Al-Nadaf, AH; Aldal'in, H; Awadallah, A; Bastoni, HM; Thiab, S | 1 |
| Chen, N; Chen, Y; Geng, D; Li, P; Liang, L; Liu, L; Liu, X; Wang, Z; Xu, J; Yang, H; Zhang, X; Zhao, K | 1 |
| Liu, Z; Zeng, H | 1 |
| Cong-Rong, T; Fan, Y; Hai-Na, Z; Jing, L; Lei-Mei, X; Ruo-Lan, S; Xu-Ben, Y; Yan-Cheng, C; Ye-Xuan, W | 1 |
| Huerta, M; Huerta-Cervantes, M; Manzo-Avalos, S; Noriega-Cisneros, R; Peña-Montes, DJ; Saavedra-Molina, A; Salgado-Garciglia, R; Torres-Martínez, R | 1 |
| Jia, W; Li, J; Liu, F; Liu, W; Lu, H; Lu, J; Yu, M | 1 |
| Alshogran, OY; Alzoubi, KH; El-Elimat, T; Nusair, SD; Obeidat, A; Sweidan, M | 1 |
| Awortwe, C; Joubert, E; Louw, J; Muller, CJF; Patel, O; Rosenkranz, B | 1 |
| Maraqa, AD | 1 |
| Amour, J; Biais, M; Birenbaum, A; Bonnefont-Rousselot, D; Cagnard, N; Carillion, A; Carpentier, W; Feldman, S; Hatem, S; Loyer, X; Na, N; Riou, B | 1 |
| Chatsudthipong, V; Chattipakorn, N; Jaikumkao, K; Lungkaphin, A; Pongchaidecha, A; Thongnak, L | 1 |
| Sun, J; Sun, Z; Yang, B; Yuan, Y | 1 |
| Chattipakorn, K; Chattipakorn, SC; Jaiwongkam, T; Kerdphoo, S; Lungaphin, A; Pongchaidecha, A; Pratchayasakul, W; Satjaritanun, P; Thongnak, LO | 1 |
| Cervantes-Flores, M; Delgado-León, TG; López-Guzmán, OD; Lozano-Guzmán, E; Martínez-Romero, A; Sálas-Pacheco, JM; Úrtiz-Estrada, N; Vazquez-Alaniz, F; Vértiz-Hernández, ÁA | 1 |
| Camsari, UM; Ekerbicer, N; Gurpinar, T; Guvendi, G; Sisman, AR; Uysal, N | 1 |
| Li, CF; Wang, YZ; Yang, L | 1 |
| Fang, H; Hu, J; Li, M | 1 |
| Abdelfattah, S; Ahmad, Z; Hassan, SS; Motawie, A; Rizk, A; Thomann, C | 1 |
| Aktay, G; Gürsoy, ŞÖ; İlhan, N; Ünüvar, S; Uyumlu, U | 1 |
| Mohebbati, R; Niazmand, S; Paseban, M; Sahebkar, A; Sathyapalan, T | 1 |
| Feng, B; Li, X; Wang, H; Xu, L | 1 |
| Alizadeh-Fanalou, S; Amniattalab, A; Hassani-Dizaj, S; Malekinejad, H; Rezabakhsh, A; Rokhsartalab-Azar, S | 1 |
| Cai, W; Cao, Y; Chen, X; Li, S; Ma, W; Su, J; Wang, F; Zou, W | 1 |
| Aslam, M; Bhattacharya, SK; Galav, V; Jafri, AA; Madhu, SV | 1 |
| Casiano, H; Crespo, MJ; Cruz, N; Hernandez, C; Quidgley, J; Rivera, K; Torres, H | 1 |
| Chang, CY; Chang, KC; Chang, RW; Chen, YS; Ko, WJ; Ko, YH; Tsai, PR; Wang, CH; Wang, SS; Young, TH | 1 |
| Chaudagar, KK; Mehta, AA | 1 |
| Akdemir, A; Aktug, H; Erbas, O; Ergenoglu, M; Taskiran, D; Yavasoglu, A; Yildirim, N; Zeybek, B | 1 |
| Deng, T; Li, H; Li, Y; Tian, L; Zhao, P; Zhou, S | 1 |
| Bento, CF; Fernandes, R; Matafome, P; Pereira, P; Seiça, RM; Sena, CM | 1 |
| Corbalan, JJ; Dawoud, H; Jacob, RF; Malinski, T; Mason, RP | 1 |
| Kumar, V; Singh, A; Singh, BK | 1 |
| Bi, MC; Shi, H; Song, E; Song, XJ; Xu, CL; Xue, WX | 1 |
| Agarwal, M; Dash, RP; Ellendula, B; Nivsarkar, M | 1 |
| Chen, Y; Hu, M; Ling, Z; Liu, C; Liu, L; Liu, X; Shu, N; Xu, P; Zhang, J; Zhang, M; Zhong, Z | 1 |
| Liao, D; Liu, YQ; Xiong, LY; Zhang, L | 1 |
| Botelho, T; de Batista, PR; Padilha, AS; Ribeiro-Júnior, RF; Simões, FV; Vassallo, DV | 1 |
| Dong, J; Liao, L; Liu, F; Liu, J; Mou, Y; Shen, X; Yang, T; Zhou, X | 1 |
| Aldhamy, SE; Elsawy, MM; Elseweidy, MM; Saeid, SA; Zein, N | 1 |
| Hu, M; Li, F; Ling, Z; Liu, L; Liu, P; Liu, X; Shu, N; Sun, B; Wang, F; Xie, Q; Xu, P; Zhang, M; Zhong, Z | 1 |
| Chaturvedi, CP; Chaudhary, DK; Ecelbarger, CM; Godbole, MM; Kumar, P; Mohan, A; Singh, RS; Tiwari, S | 1 |
| Chai, YM; Chen, HH; Jia, YC; Kang, QL; Xu, J | 1 |
| Cho, SY; Kim, SW; Kwon, OS; Paick, JS; Park, J | 1 |
| Chen, XM; Field, MJ; Kelly, DJ; Mangiafico, S; Mather, A; McGinn, S; Pollock, CA; Sumual, S; Zhang, Y | 1 |
| Amaral, C; Cipriano, A; Crisóstomo, J; Louro, T; Matafome, P; Moedas, AR; Monteiro, P; Nunes, E; Rodrigues, L; Seiça, R | 1 |
| Bantly, A; Hamamdzic, D; Mohler, ER; Moore, J; Parmacek, M; Putt, M; Rader, DJ; Shi, Y; Wilensky, RL; Yoder, M; Zhang, L | 1 |
| Chavalmane, AK; Fibbi, B; Filippi, S; Forti, G; Maggi, M; Morelli, A; Sarchielli, E; Silvestrini, E; Vannelli, GB; Vignozzi, L; Zhang, XH | 1 |
| Boyle, A; Connelly, KA; Gilbert, RE; Kelly, D; Kompa, A; Krum, H; Martin, JH; Zhang, Y | 1 |
| Cayc, MK; Erbilen, E; Gulcan, E; Olgun, EG; Ozay, Y; Toker, S | 1 |
| Chen, L; Ding, G; Jia, R; Tu, Y | 1 |
| Bijjem, KV; Goyal, S; Kumar, S; Singh, M | 1 |
| Arany, EJ; Hill, DJ; Marchand, KC | 1 |
| Barut, T; Ekerbiçer, N; Gürpınar, T; Harzadın, NU; Tarakçı, F; Tuglu, MI | 1 |
| Sharma, PL; Sharma, S; Singh, M | 1 |
| Bando, YK; Monji, A; Morimoto, Y; Murohara, T; Shigeta, T | 1 |
| Gade, J; Neerati, P | 1 |
| Amaral, C; Cipriano, A; Crisóstomo, J; Louro, T; Matafome, P; Monteiro, P; Nunes, E; Rodrigues, L; Seiça, R | 1 |
| Ahmed, D; Pillai, KK; Sharma, M | 1 |
| Chen, QJ; Lu, L; Peng, WH; Shen, WF; Wang, LJ; Wang, W | 1 |
| Reddy, PJ; Sekhar, MC | 1 |
| Cao, Y; Fan, Y; Huang, Y; Yang, S; Zhang, X | 1 |
| Dixon, JL; Shen, S; Sturek, M; Sun, GY; Vuchetich, JP; Wysocka, E | 1 |
| Ichihara, K; Kanda, M; Satoh, K | 1 |
| Kakuta, H; Kihara, R; Shimano, H; Suzuki, M; Tada-Iida, K; Takahashi, A; Yamada, N; Yokoo, T | 1 |
| Kummerow, FA; Mahfouz, MM | 1 |
| Brumeanu, TD; Casares, S; Goldstein, R | 1 |
| Shah, DI; Singh, M | 1 |
| Dhayat, N; Dhayat, S; Du, J; Hilfiker-Kleiner, D; Laufs, U; Noutsias, M; Riad, A; Schultheiss, HP; Spillmann, F; Tschöpe, C; Van Linthout, S; Westermann, D | 1 |
| Adams, V; Doehner, W; Du, J; Mohr, Z; Pauschinger, M; Riad, A; Schultheiss, HP; Sobirey, M; Stiehl, S; Tschöpe, C; Westermann, D | 1 |
| Bauersachs, J; Brandt, M; Closs, E; Daiber, A; Ertl, G; Förstermann, U; Münzel, T; Oelze, M; Thum, T; Wenzel, P; Xu, J; Zou, MH | 1 |
| Dixon, JL; Hill, BJ; Sturek, M | 1 |
1 review(s) available for atorvastatin and Alloxan Diabetes
| Article | Year |
|---|---|
Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors.
Topics: Animals; Antigen-Presenting Cells; Atorvastatin; Autoimmune Diseases; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Down-Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; T-Lymphocytes | 2006 |
75 other study(ies) available for atorvastatin and Alloxan Diabetes
| Article | Year |
|---|---|
Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.
Topics: Animals; Binding Sites; Blood Glucose; Crystallography, X-Ray; Diabetes Mellitus, Experimental; Dogs; Fluorescence Resonance Energy Transfer; Humans; Isoxazoles; Ligands; Mice; Molecular Conformation; Naphthalenes; Protein Structure, Tertiary; Quinolines; Rats; Receptors, Cytoplasmic and Nuclear; Weight Gain | 2011 |
Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats.
Topics: Animals; Atorvastatin; Bee Venoms; Diabetes Mellitus, Experimental; Diet, High-Fat; Heart; Hyperlipidemias; Male; Metformin; Rats | 2021 |
Atorvastatin prevents the development of diabetic neuropathic nociception by possible involvement of nitrergic system.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociception; Rats; Streptozocin | 2021 |
The vascular impact of dapagliflozin, liraglutide, and atorvastatin alone or in combinations in type 2 diabetic rat model.
Topics: Animals; Atorvastatin; Benzhydryl Compounds; C-Reactive Protein; Cholesterol, LDL; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucosides; Glycated Hemoglobin; Liraglutide; Male; Pyrroles; Rats; Thyrotropin | 2022 |
Impact of atorvastatin on plasma and cardiac biomarkers of inflammation, oxidative stress, and fibrosis in a rat model of streptozotocin-induced diabetes.
Topics: Animals; Atorvastatin; Biomarkers; Diabetes Mellitus, Experimental; Fibrosis; Inflammation; Male; Nitrites; Oxidants; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Thiobarbituric Acid Reactive Substances | 2023 |
Methanolic extract of S. securidaca flowers, leaves, and seeds' antihyperlipidemic effects on high fat diet-induced hyperlipidemia in Wistar rats.
Topics: Animals; Antioxidants; Atorvastatin; Cholesterol; Diabetes Mellitus, Experimental; Diet, High-Fat; Flowers; Hyperlipidemias; Hypolipidemic Agents; Methanol; Plant Extracts; Rats; Rats, Wistar; Securidaca; Seeds | 2023 |
Prediction of Atorvastatin Pharmacokinetics in High-Fat Diet and Low-Dose Streptozotocin-Induced Diabetic Rats Using a Semiphysiologically Based Pharmacokinetic Model Involving Both Enzymes and Transporters.
Topics: Animals; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cells, Cultured; Cytochrome P-450 CYP3A; Diabetes Mellitus, Experimental; Diet, High-Fat; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Mucosa; Male; Microsomes, Liver; Models, Biological; Primary Cell Culture; Rats; Solute Carrier Organic Anion Transporter Family Member 1B3; Streptozocin | 2019 |
Atorvastatin Induces Hepatotoxicity in Diabetic Rats via Oxidative Stress, Inflammation, and Anti-Apoptotic Pathway.
Topics: Animals; Antioxidants; Apoptosis; Atorvastatin; Blood Glucose; Chemical and Drug Induced Liver Injury; China; Diabetes Mellitus, Experimental; Hepatocytes; Inflammation; Liver; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase | 2019 |
Atorvastatin ameliorates depressive behaviors and neuroinflammatory in streptozotocin-induced diabetic mice.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Depression; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hindlimb Suspension; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Male; Mice; Prefrontal Cortex; Streptozocin; Tumor Necrosis Factor-alpha | 2020 |
Topics: Animals; Atorvastatin; Cholesterol; Diabetes Mellitus, Experimental; Eryngium; Ethanol; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Lipids; Microsomes, Liver; Plant Extracts; Rats; Rats, Wistar | 2020 |
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway.
Topics: Animals; Atorvastatin; Cell Proliferation; Diabetes Mellitus, Experimental; Exosomes; Mesenchymal Stem Cells; MicroRNAs; Neovascularization, Physiologic; Proto-Oncogene Proteins c-akt; Rats; Vascular Endothelial Growth Factor A; Wound Healing | 2020 |
Evaluation of coenzyme Q10 combined with or without N-acetyl cysteine or atorvastatin for preventing contrast-induced kidney injury in diabetic rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Atorvastatin; Contrast Media; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Drug Therapy, Combination; Male; Rats; Rats, Sprague-Dawley; Ubiquinone | 2021 |
Therapeutic effects of an aspalathin-rich green rooibos extract, pioglitazone and atorvastatin combination therapy in diabetic db/db mice.
Topics: Animals; Aspalathus; Atorvastatin; Blood Glucose; Chalcones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glucose; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred Strains; Phytotherapy; Pioglitazone; Plant Extracts | 2021 |
Effect of atorvastatin on interleukins and prostaglandin E2 in the kidney of type 1 diabetic rats.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dinoprostone; Interleukin-1; Kidney; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar; Tumor Necrosis Factor-alpha | 2016 |
Atorvastatin reduces β-Adrenergic dysfunction in rats with diabetic cardiomyopathy.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Papillary Muscles; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 2017 |
The additive effects of atorvastatin and insulin on renal function and renal organic anion transporter 3 function in diabetic rats.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Interleukin-6; Kidney; Male; Malondialdehyde; Organic Anion Transporters, Sodium-Independent; Oxidative Stress; Pancreas; Protein Kinase C-alpha; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Superoxide Dismutase | 2017 |
Effects of atorvastatin on autophagy in skeletal muscles of diabetic rats.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Autophagy; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Lipid Metabolism; Male; Microtubule-Associated Proteins; Muscle, Skeletal; Rats, Sprague-Dawley; Streptozocin | 2018 |
Atorvastatin and insulin equally mitigate brain pathology in diabetic rats.
Topics: Animals; Atorvastatin; Blood Glucose; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Hypoglycemic Agents; Insulin; Male; Oxidative Stress; Rats; Rats, Wistar | 2018 |
Apoptosis in pancreatic β-cells is induced by arsenic and atorvastatin in Wistar rats with diabetes mellitus type 2.
Topics: Animals; Antioxidants; Apoptosis; Arsenic; Atorvastatin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin-Secreting Cells; Male; Rats, Inbred WKY; Streptozocin | 2018 |
Statins reduce testicular and ocular VEGF: A potential compromise to microcirculation.
Topics: Angiogenesis Inhibitors; Animals; Atorvastatin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Down-Regulation; Eye; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Microcirculation; Neovascularization, Pathologic; Rats, Wistar; Testis; Vascular Endothelial Growth Factor A | 2018 |
Protective effect of atorvastatin meditated by HMGCR gene on diabetic rats with atherosclerosis: An in vivo and in vitro study.
Topics: Animals; Atherosclerosis; Atorvastatin; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Experimental; Fatty Acid Synthase, Type I; Female; Hydroxymethylglutaryl CoA Reductases; Insulin; Male; Protective Agents; Rats; Rats, Wistar; Receptors, LDL; RNA, Messenger; Triglycerides | 2018 |
Apelin‑13 ameliorates metabolic and cardiovascular disorders in a rat model of type 2 diabetes with a high‑fat diet.
Topics: Animals; Atorvastatin; Biomarkers; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Heart Function Tests; Hemodynamics; Intercellular Signaling Peptides and Proteins; Lipid Metabolism; Male; Metformin; Oxidation-Reduction; Protective Agents; Rats | 2018 |
Preconditioning with atorvastatin against renal ischemia-reperfusion injury in nondiabetic versus diabetic rats.
Topics: Acute Kidney Injury; Animals; Atorvastatin; Diabetes Mellitus, Experimental; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Preconditioning; Kidney Cortex; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2019 |
Protective effect of atorvastatin on oxidative stress in streptozotocin-induced diabetic rats independently their lipid-lowering effects.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Atorvastatin; Blood Glucose; Diabetes Mellitus, Experimental; Female; Lipid Peroxidation; Lipids; Nitric Oxide; Organ Specificity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances | 2019 |
Comparison of the Neuroprotective Effects of Aspirin, Atorvastatin, Captopril and Metformin in Diabetes Mellitus.
Topics: Animals; Aspirin; Atorvastatin; Captopril; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Metformin; Neuroprotective Agents; Rats; Rats, Wistar; Streptozocin | 2019 |
Multiple statistical methods for assessing differential gene expression in microarray data of diabetic model rats to predict the molecular mechanism of atorvastatin on anti-atherogenesis.
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Data Interpretation, Statistical; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Gene Expression Profiling; Heptanoic Acids; Male; Microarray Analysis; Prognosis; Pyrroles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Streptozocin; Treatment Outcome | 2013 |
Effects of silymarin on the pharmacokinetics of atorvastatin in diabetic rats.
Topics: Animals; Atorvastatin; Cytochrome P-450 CYP3A; Diabetes Mellitus, Experimental; Drug Interactions; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Pyrroles; Rats; Rats, Wistar; Silymarin; Streptozocin; Testosterone | 2014 |
Atorvastatin ameliorates contrast medium-induced renal tubular cell apoptosis in diabetic rats via suppression of Rho-kinase pathway.
Topics: Acute Kidney Injury; Animals; Apoptosis; Atorvastatin; bcl-2-Associated X Protein; Caspase 3; Contrast Media; Diabetes Mellitus, Experimental; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iohexol; Kidney Tubules; Male; Protein Phosphatase 1; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Rats; Rats, Wistar; rho-Associated Kinases | 2014 |
Atorvastatin prevents type 2 diabetes mellitus--an experimental study.
Topics: Animals; Atorvastatin; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Lipid Metabolism; Male; Pyrroles; Rats; Rats, Wistar; Triglycerides | 2014 |
Daily administration of atorvastatin and simvastatin for one week improves cardiac function in type 1 diabetic rats.
Topics: Animals; Atorvastatin; Blood Glucose; Cardiac Output; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Administration Schedule; Heart; Heart Rate; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pravastatin; Pyrroles; Rats; Rats, Sprague-Dawley; Simvastatin; Ventricular Function, Left | 2014 |
Prevention of arterial stiffening by using low-dose atorvastatin in diabetes is associated with decreased malondialdehyde.
Topics: Animals; Arginine; Atorvastatin; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fatty Acids; Glycation End Products, Advanced; Hemodynamics; Heptanoic Acids; Lysine; Male; Malondialdehyde; Organ Size; Pyrroles; Rats, Wistar; Streptozocin; Vascular Stiffness | 2014 |
Effect of atorvastatin on the angiogenic responsiveness of coronary endothelial cells in normal and streptozotocin (STZ) induced diabetic rats.
Topics: Androstadienes; Animals; Anticholesteremic Agents; Atorvastatin; Benzophenanthridines; Chick Embryo; Chorioallantoic Membrane; Coronary Vessels; Diabetes Mellitus, Experimental; Endothelial Cells; Enzyme Inhibitors; Heptanoic Acids; Male; Myocardial Reperfusion Injury; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyrroles; Rats; Rats, Wistar; Streptozocin; Vascular Endothelial Growth Factor A; Wortmannin | 2014 |
High-dose atorvastatin ameliorates the uterine microenvironment in streptozotocin-induced diabetic rats.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Endometrium; ErbB Receptors; Female; Fibrosis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Uterus; Vascular Endothelial Growth Factor A | 2014 |
Renoprotective effect of atorvastatin on STZ-diabetic rats through attenuating kidney-associated dysmetabolism.
Topics: Animals; Atorvastatin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin; Kidney; Lipoproteins, HDL; Lipoproteins, LDL; Male; Proteinuria; Pyrroles; Rats, Sprague-Dawley; RNA, Messenger; Streptozocin; Transforming Growth Factor beta1 | 2014 |
Atorvastatin-mediated protection of the retina in a model of diabetes with hyperlipidemia.
Topics: Animals; Antioxidants; Atorvastatin; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diet, Atherogenic; Heptanoic Acids; Hyperlipidemias; Insulin Resistance; Lipid Metabolism; Male; Oxidative Stress; Proteasome Endopeptidase Complex; Pyrroles; Rats; Reactive Oxygen Species; Retina; Ubiquitin | 2014 |
Atorvastatin enhanced nitric oxide release and reduced blood pressure, nitroxidative stress and rantes levels in hypertensive rats with diabetes.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Atorvastatin; Biomarkers; Blood Glucose; Blood Pressure; Chemokine CCL5; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelial Cells; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Rats, Inbred SHR | 2015 |
Ameliorative Effect of Adjunct Therapy of Metformin with Atorvastatin on Streptozotocin-induced Diabetes Mellitus in Rats.
Topics: Animals; Antioxidants; Atorvastatin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Lipids; Lipoproteins, HDL; Male; Metformin; Rats; Rats, Wistar; Streptozocin; Triglycerides | 2016 |
Effect of atorvastatin on diabetic rat endothelial cells and retinal lesions.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Cells; Gene Expression Regulation, Neoplastic; Humans; Interleukin-4; Rats; Rats, Wistar; Tumor Necrosis Factor Ligand Superfamily Member 15; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2015 |
Increased intestinal P-glycoprotein expression and activity with progression of diabetes and its modulation by epigallocatechin-3-gallate: Evidence from pharmacokinetic studies.
Topics: Animals; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Catechin; Diabetes Mellitus, Experimental; Disease Progression; Ileum; Intestinal Absorption; Male; Rats; Sodium-Potassium-Exchanging ATPase; Verapamil | 2015 |
Decreased exposure of atorvastatin in diabetic rats partly due to induction of hepatic Cyp3a and Oatp2.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cytochrome P-450 CYP3A; Diabetes Mellitus, Experimental; Hepatocytes; Liver; Organic Anion Transporters; Rats | 2016 |
Renoprotective effect of atorvastatin on STZ-diabetic rats through inhibiting inflammatory factors expression in diabetic rat.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Rats; Streptozocin | 2016 |
Treatment with high dose of atorvastatin reduces vascular injury in diabetic rats.
Topics: Animals; Aorta; Atorvastatin; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Endothelium, Vascular; Indomethacin; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitrobenzenes; Phenylephrine; Prostaglandins; Rats; Rats, Wistar; Streptozocin; Sulfonamides; Superoxides; Vascular System Injuries; Vasodilation; Vasodilator Agents | 2016 |
The role of atorvastatin on the restenosis process post-PTA in a diabetic rabbit model.
Topics: Angioplasty, Balloon; Animals; Atherosclerosis; Atorvastatin; Cell Movement; Cell Proliferation; Constriction, Pathologic; Diabetes Mellitus, Experimental; Disease Models, Animal; Iliac Artery; Male; Myocytes, Smooth Muscle; Neointima; Rabbits; Recurrence; Time Factors; Vascular Patency; Vascular System Injuries | 2016 |
Policosanol as a new inhibitor candidate for vascular calcification in diabetic hyperlipidemic rats.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; C-Reactive Protein; Calcification, Physiologic; Diabetes Mellitus, Experimental; Diet, High-Fat; Fatty Acids, Omega-3; Fatty Alcohols; Hyperlipidemias; Male; Oxidative Stress; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Vascular Calcification | 2016 |
The enhanced atorvastatin hepatotoxicity in diabetic rats was partly attributed to the upregulated hepatic Cyp3a and SLCO1B1.
Topics: Animals; Atorvastatin; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Diabetes Mellitus, Experimental; Hepatocytes; Liver-Specific Organic Anion Transporter 1; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Up-Regulation | 2016 |
Greater efficacy of atorvastatin versus a non-statin lipid-lowering agent against renal injury: potential role as a histone deacetylase inhibitor.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Ezetimibe; Histone Deacetylase Inhibitors; Histone Deacetylases; Kidney; Male; Rats; Rats, Wistar | 2016 |
The Effect of Atorvastatin on the Viability of Ischemic Skin Flaps in Diabetic Rats.
Topics: Animals; Atorvastatin; Cell Movement; Diabetes Mellitus, Experimental; Endothelial Progenitor Cells; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemia; Male; Postoperative Complications; Rats; Rats, Sprague-Dawley; Surgical Flaps; Tissue Survival | 2017 |
Chronic administration of atorvastatin could partially ameliorate erectile function in streptozotocin-induced diabetic rats.
Topics: Administration, Intravenous; Animals; Arterial Pressure; Atorvastatin; Diabetes Mellitus, Experimental; Erectile Dysfunction; Male; Malondialdehyde; Penile Erection; Pyrimidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Superoxide Dismutase | 2017 |
High glucose induced endothelial cell growth inhibition is associated with an increase in TGFbeta1 secretion and inhibition of Ras prenylation via suppression of the mevalonate pathway.
Topics: Animals; Atorvastatin; Cell Proliferation; Diabetes Mellitus, Experimental; Down-Regulation; Endothelial Cells; Glucose; Heptanoic Acids; Humans; Kidney; Male; Mevalonic Acid; Oncogene Protein p21(ras); Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Prenylation; Pyrroles; Rats; Signal Transduction; Transforming Growth Factor beta1; Umbilical Veins | 2009 |
A role for atorvastatin and insulin combination in protecting from liver injury in a model of type 2 diabetes with hyperlipidemia.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Atorvastatin; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Drug Therapy, Combination; Fatty Liver; Heptanoic Acids; Hyperlipidemias; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Resistance; Lipids; Oxidative Stress; Pyrroles; Rats; Rats, Inbred Strains | 2009 |
Diabetes reduces bone marrow and circulating porcine endothelial progenitor cells, an effect ameliorated by atorvastatin and independent of cholesterol.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Antibiotics, Antineoplastic; Anticholesteremic Agents; Atorvastatin; Azetidines; Bone Marrow Cells; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelial Cells; Ezetimibe; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Stem Cells; Swine; Vasodilation | 2009 |
Atorvastatin ameliorates sildenafil-induced penile erections in experimental diabetes by inhibiting diabetes-induced RhoA/Rho-kinase signaling hyperactivation.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Disease Models, Animal; Electric Stimulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Penile Erection; Phosphodiesterase Inhibitors; Phosphorylation; Piperazines; Purines; Pyrroles; Rabbits; rho-Associated Kinases; Signal Transduction; Sildenafil Citrate; Sulfones | 2009 |
Effect of atorvastatin on cardiac remodelling and mortality in rats following hyperglycemia and myocardial infarction.
Topics: Animals; Atorvastatin; Body Weight; Cardiac Volume; Collagen Type I; Collagen Type III; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Fibrosis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Myocardial Infarction; Myocardium; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2010 |
Topical atorvastatin in the treatment of diabetic wounds.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Diabetes Mellitus, Experimental; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pyrroles; Rats; Rats, Wistar; Wound Healing; Wounds and Injuries | 2009 |
Effect of atorvastatin on dendritic cells of tubulointerstitium in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Cell Movement; Dendritic Cells; Diabetes Mellitus, Experimental; Disease Models, Animal; Heptanoic Acids; Nephritis, Interstitial; P-Selectin; Pyrroles; Rats | 2010 |
Role of glucagon-like peptide- 1 in vascular endothelial dysfunction.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Endothelium, Vascular; Exenatide; Female; Glucagon-Like Peptide 1; Heptanoic Acids; Hyperhomocysteinemia; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Peptides; Pyrroles; Rats; Rats, Wistar; Venoms | 2010 |
Effects of atorvastatin on the regeneration of pancreatic {beta}-cells after streptozotocin treatment in the neonatal rodent.
Topics: Animals; Animals, Newborn; Atorvastatin; Body Weight; Diabetes Mellitus, Experimental; Female; Glucose Tolerance Test; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Male; Neovascularization, Physiologic; Organ Size; Pregnancy; Pyrroles; Rats; Rats, Wistar | 2010 |
Statin treatment reduces oxidative stress-associated apoptosis of sciatic nerve in diabetes mellitus.
Topics: Animals; Apoptosis; Atorvastatin; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nitric Oxide Synthase; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Sciatic Nerve; Streptozocin; Transforming Growth Factor beta1 | 2011 |
Beneficial effect of insulin in hyperhomocysteinemia and diabetes mellitus-induced vascular endothelium dysfunction: role of phosphoinositide dependent kinase and protein kinase B.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Atorvastatin; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Hypoglycemic Agents; Insulin; Male; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Vasodilation; Vasodilator Agents | 2011 |
Atorvastatin prevents ischemic limb loss in type 2 diabetes: role of p53.
Topics: Animals; Atorvastatin; Blotting, Western; Cells, Cultured; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Extremities; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin Resistance; Ischemia; Male; Mice; Myoblasts; Peripheral Arterial Disease; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Pyrroles; Tumor Suppressor Protein p53; Ubiquitin; Wound Healing | 2011 |
Influence of atorvastatin on the pharmacokinetics and pharmacodynamics of glyburide in normal and diabetic rats.
Topics: Animals; Anticholesteremic Agents; Area Under Curve; Atorvastatin; Blood Glucose; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Female; Glyburide; Half-Life; Heptanoic Acids; Hypoglycemic Agents; Male; Pyrroles; Rats; Rats, Wistar | 2011 |
Metformin and atorvastatin combination further protect the liver in type 2 diabetes with hyperlipidaemia.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Body Weight; C-Reactive Protein; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Combinations; Fatty Liver; Heptanoic Acids; Hyperlipidemias; Hypoglycemic Agents; Insulin Resistance; Interleukin-6; Liver; Metformin; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Pyrroles; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 2011 |
The effects of triple vs. dual and monotherapy with rosiglitazone, glimepiride, and atorvastatin on lipid profile and glycemic control in type 2 diabetes mellitus rats.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Atorvastatin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Synergism; Drug Therapy, Combination; Female; Glycated Hemoglobin; Heptanoic Acids; Hypolipidemic Agents; Lipids; Male; Pyrroles; Rats; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones | 2012 |
Effects of atorvastatin on progression of diabetic nephropathy and local RAGE and soluble RAGE expressions in rats.
Topics: Animals; Atorvastatin; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Male; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Streptozocin | 2011 |
Influence of atorvastatin on the pharmacodynamic and pharmacokinetic activity of repaglinide in rats and rabbits.
Topics: Animals; Atorvastatin; Blood Glucose; Carbamates; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Diabetes Mellitus, Experimental; Drug Interactions; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Piperidines; Pyrroles; Rabbits; Rats | 2012 |
Comparison of cardioprotective efficacy resulting from a combination of atorvastatin and ischaemic post-conditioning in diabetic and non-diabetic rats.
Topics: Animals; Atorvastatin; Cardiotonic Agents; Diabetes Mellitus, Experimental; Heart; Hemodynamics; Heptanoic Acids; Ischemic Postconditioning; Male; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Wistar; Signal Transduction | 2012 |
Increased atherosclerosis in diabetic dyslipidemic swine: protection by atorvastatin involves decreased VLDL triglycerides but minimal effects on the lipoprotein profile.
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Blood Glucose; Cholesterol; Collagen; Diabetes Mellitus, Experimental; Diet, Atherogenic; Fasting; Heptanoic Acids; Hyperlipidemias; Insulin; Lipoproteins, VLDL; Liver; Male; Pyrroles; Swine; Swine, Miniature; Triglycerides; Vitamin A; Vitamin E | 2002 |
Effects of atorvastatin and pravastatin on glucose tolerance in diabetic rats mildly induced by streptozotocin.
Topics: Administration, Oral; Animals; Atorvastatin; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Glucose; Glucose Tolerance Test; Heptanoic Acids; Injections, Intravenous; Insulin; Insulin Secretion; Male; Pravastatin; Pyrroles; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors | 2003 |
Effects of atorvastatin on glucose metabolism and insulin resistance in KK/Ay mice.
Topics: Animals; Arteriosclerosis; Atorvastatin; Biomarkers; Blood Glucose; Blotting, Northern; CCAAT-Enhancer-Binding Proteins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Glucose Tolerance Test; Glucose-6-Phosphatase; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin Resistance; Lipids; Male; Mice; Mice, Inbred Strains; Pyrroles; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Transcription Factors | 2005 |
Atorvastatin reduces the plasma lipids and oxidative stress but did not reverse the inhibition of prostacyclin generation by aortas in streptozotocin diabetic rats.
Topics: Animals; Aorta; Atorvastatin; Diabetes Mellitus, Experimental; Epoprostenol; Heptanoic Acids; Lipids; Male; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Streptozocin | 2005 |
Involvement of Rho-kinase in experimental vascular endothelial dysfunction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Antibiotics, Antineoplastic; Aorta, Thoracic; Atorvastatin; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Endothelium, Vascular; Heptanoic Acids; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Intracellular Signaling Peptides and Proteins; Male; Nitrates; Nitrites; Oxidative Stress; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrroles; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Streptozocin; Thiobarbituric Acid Reactive Substances; Vasodilation | 2006 |
Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Heart; Heptanoic Acids; Inflammation; Myocardium; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Left; Ventricular Function, Left | 2007 |
Low-dose treatment with atorvastatin leads to anti-oxidative and anti-inflammatory effects in diabetes mellitus.
Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Antioxidants; Atorvastatin; Diabetes Mellitus, Experimental; Endothelium, Vascular; Gene Expression; Heptanoic Acids; Inflammation; Inflammation Mediators; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Oxidative Stress; Phosphorylation; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Streptozocin; Transcription Factor RelA; Vasodilation | 2007 |
Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.
Topics: Animals; Atorvastatin; Biopterins; Body Weight; Cell Adhesion Molecules; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; GTP Cyclohydrolase; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intramolecular Oxidoreductases; Male; Microfilament Proteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoproteins; Pyrroles; Rats; Rats, Wistar; Stem Cells; Tetrahydrofolate Dehydrogenase; Vasodilation | 2008 |
Effect of atorvastatin on intracellular calcium uptake in coronary smooth muscle cells from diabetic pigs fed an atherogenic diet.
Topics: Animals; Atorvastatin; Caffeine; Calcium; Coronary Vessels; Cytoplasm; Diabetes Mellitus, Experimental; Diet, Atherogenic; Fluorescent Dyes; Fura-2; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; In Vitro Techniques; Ionomycin; Ionophores; Male; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Pyrroles; Sarcoplasmic Reticulum; Sodium; Swine; Swine, Miniature; Thapsigargin | 2001 |