atorvastatin has been researched along with Aging in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 19 (63.33) | 24.3611 |
| 2020's | 4 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Battegay, M; Cavassini, M; Courlet, P; Decosterd, L; Marzolini, C; Saldanha, SA; Stader, F; Stoeckle, M | 1 |
| Alves Saldanha, S; Buclin, T; Cavassini, M; Courlet, P; Csajka, C; Decosterd, LA; Guidi, M; Marzolini, C; Stader, F; Stoeckle, M | 1 |
| Gao, Q; Gao, T; Guan, L; Hu, Y; Jiang, J; Li, T; Liu, P; Qiao, H; Sheng, W; Xue, X | 1 |
| Hoffmann, TJ; Iribarren, C; Krauss, RM; Lu, B; Medina, MW; Oni-Orisan, A; Risch, N; Seraydarian, M; Sun, L | 1 |
| Allahtavakoli, M; Fatemi, I; Kaeidi, A; Kaviani, E; Mozafari, N; Rahmani, M; Shamsizadeh, A | 1 |
| Koca, RÖ; Kutlu, S; Nurullahoğlu-Atalık, KE; Solak, H | 1 |
| Becker, ML; de Keyser, CE; Hofman, A; Klungel, OH; Maitland-van der Zee, AH; Peters, BJ; Stricker, BH; Uitterlinden, AG; Verstuyft, C; Visser, LE | 1 |
| Han, L; Li, MG; Ye, P | 1 |
| Fu, G; Gong, X; Ma, Y; Ruan, Y; Wu, S | 1 |
| de Ceuninck, M; Trenson, S | 1 |
| de Oliveira, RM; Ferreira, ED; Godinho, J; Milani, H; Previdelli, IS; Ribeiro, MH; Zaghi, GG | 1 |
| Aubry, T; Bourgeois, N; Desfontis, JC; Didier, R; Dubreuil, M; Gilard, M; Goanvec, C; Le Grand, Y; Mallem, Y; Mansourati, J; Pichavant-Rafini, K; Plee-Gautier, E; Roquefort, P; Theron, M; Tissier, F | 1 |
| Camerino, C; Camerino, GM; Cannone, M; Conte Camerino, D; Conte, E; De Bellis, M; De Luca, A; Desaphy, JF; Fonzino, A; Giustino, A; Laghezza, A; Liantonio, A; Loiodice, F; Musaraj, K; Pierno, S; Romano, R | 1 |
| Chen, F; Chen, H; Cui, W; Jin, Y; Liu, D; Liu, F; Lu, J | 1 |
| Cui, W; Du, J; Han, M; Liu, DM; Liu, F; Lu, JC; Yin, HN; Zhang, HL; Zhang, K | 1 |
| Davy, KP; Dengo, AL; Orr, JS; Rivero, JM | 1 |
| Astarita, G; Barrett, E; Beckett, TL; Dowling, AL; Head, E; Kryscio, RJ; Levine, H; Lin, Y; Morales, J; Murphy, MP; Piomelli, D; Studzinski, CM; Wang, X; Weidner, A | 1 |
| Abe, K; Ikeda, Y; Kozuki, M; Kurata, T; Matsuura, T; Miyazaki, K; Morimoto, N; Nagai, M; Ohta, Y; Panin, VL | 1 |
| Clarke, R; Lynch, MA; Lyons, A; Murphy, KJ | 1 |
| Cheng, QL; Ye, P; Zhao, JH | 1 |
| Barone, E; Butterfield, DA; Cenini, G; Dowling, AL; Head, E; Mancuso, C; Martin, SB; Murphy, MP | 1 |
| Han, C; Han, L; Li, M; Liu, Y; Ye, P | 1 |
| Wang, H; Ye, P; Zhang, JY | 1 |
| Guo, Y; Wang, J; Xu, D; Xu, J; Yang, Z; Zhang, Y; Zhou, C | 1 |
| Fürst, DO; Granzow, M; Huss, S; Klein, S; Klösel, J; Körner, C; Lammert, F; Mazar, IG; Nattermann, J; Pieper-Fürst, U; Sauerbruch, T; Schierwagen, R; Trebicka, J; van den Ven, PF; Weber, S | 1 |
| Blauw, GJ; Meinders, AE; Weverling-Rijnsburger, AW | 1 |
| Baumeister, B; Berthold, HK; Degenhardt, R; Gouni-Berthold, I; Krone, W; Unverdorben, M; Unverdorben, S; Vetter, H; Zittermann, A | 1 |
| Alegret, M; Laguna, JC; Roglans, N; Sánchez, RM; Sanguino, E; Vázquez-Carrera, M | 1 |
| Nachtigal, P; Ouda, L; Semecký, V; Solichová, D; Syka, J | 1 |
| Arca, M | 1 |
2 review(s) available for atorvastatin and Aging
| Article | Year |
|---|---|
The SLCO1B1 c.521T>C polymorphism is associated with dose decrease or switching during statin therapy in the Rotterdam Study.
Topics: Aged; Aging; Anticholesteremic Agents; Atorvastatin; Cholesterol; Cytosine; Databases, Factual; Dose-Response Relationship, Drug; Female; Genetic Association Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Organic Anion Transporters; Polymorphism, Single Nucleotide; Prospective Studies; Pyrroles; Risk Factors; Sex Characteristics; Simvastatin; Thymine | 2014 |
Atorvastatin: a safety and tolerability profile.
Topics: Aged; Aging; Alanine Transaminase; Aspartate Aminotransferases; Atorvastatin; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Pyrroles | 2007 |
2 trial(s) available for atorvastatin and Aging
| Article | Year |
|---|---|
Arterial destiffening with atorvastatin in overweight and obese middle-aged and older adults.
Topics: Adult; Aged; Aging; Atorvastatin; Blood Flow Velocity; C-Reactive Protein; Cardiovascular Diseases; Carotid Arteries; Cholesterol, LDL; Double-Blind Method; Elasticity; Female; Femoral Artery; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Obesity; Overweight; Pyrroles; Regional Blood Flow; Risk Factors | 2009 |
Age-dependent effects of atorvastatin on biochemical bone turnover markers: a randomized controlled trial in postmenopausal women.
Topics: Aged; Aging; Atorvastatin; Biomarkers; Bone and Bones; Bone Density; Cardiovascular Diseases; Collagen; Collagen Type I; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Multivariate Analysis; Osteocalcin; Peptides; Postmenopause; Prospective Studies; Pyrroles; Risk Factors | 2004 |
26 other study(ies) available for atorvastatin and Aging
| Article | Year |
|---|---|
Aging does not impact drug--drug interaction magnitudes with antiretrovirals.
Topics: Aged; Aged, 80 and over; Aging; Amlodipine; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Atorvastatin; Cardiovascular Agents; Cardiovascular Diseases; Darunavir; Drug Interactions; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Male; Middle Aged; Oxazines; Piperazines; Pyridones; Rosuvastatin Calcium; Treatment Outcome | 2020 |
Influence of Drug-Drug Interactions on the Pharmacokinetics of Atorvastatin and Its Major Active Metabolite ortho-OH-Atorvastatin in Aging People Living with HIV.
Topics: Aged; Aging; Atorvastatin; Drug Interactions; Female; HIV Infections; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged | 2020 |
Atorvastatin attenuates surgery-induced BBB disruption and cognitive impairment partly by suppressing NF-κB pathway and NLRP3 inflammasome activation in aged mice.
Topics: Aging; Animals; Atorvastatin; Blood-Brain Barrier; Cognitive Dysfunction; Inflammasomes; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Surgical Procedures, Operative | 2021 |
Effect of SLCO1B1 T521C on Statin-Related Myotoxicity With Use of Lovastatin and Atorvastatin.
Topics: Aged; Aged, 80 and over; Aging; Atorvastatin; Case-Control Studies; Female; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Lovastatin; Male; Muscular Diseases; Myotoxicity; Phenotype; Polymorphism, Single Nucleotide | 2021 |
Protective effect of atorvastatin on d-galactose-induced aging model in mice.
Topics: Aging; Animals; Antioxidants; Anxiety; Atorvastatin; Brain; Brain-Derived Neurotrophic Factor; Cognition; Dose-Response Relationship, Drug; Galactose; Male; Maze Learning; Mice; Models, Animal; Nootropic Agents; Random Allocation; Recognition, Psychology; Superoxide Dismutase | 2017 |
Cilostazol enhances atorvastatin-induced vasodilation of female rat aorta during aging.
Topics: Aging; Animals; Aorta; Atorvastatin; Cilostazol; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Female; In Vitro Techniques; Rats; Rats, Wistar; Tetrazoles; Treatment Outcome; Vasodilator Agents | 2017 |
[The effect of PPARalpha signal channel on atorvastatin inhibiting MMP-9 expression in aging myocytes].
Topics: Aging; Animals; Atorvastatin; Cells, Cultured; Heptanoic Acids; Matrix Metalloproteinase 9; Muscle Cells; Oxazoles; PPAR alpha; Pyrroles; Rats; Rats, Wistar; Signal Transduction; Tyrosine | 2013 |
Long-term atorvastatin improves age-related endothelial dysfunction by ameliorating oxidative stress and normalizing eNOS/iNOS imbalance in rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Atorvastatin; Body Weight; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Pyrroles; Rats, Wistar; Sirtuin 1 | 2014 |
A calcified left ventricular mass.
Topics: Aged, 80 and over; Aging; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Calcinosis; Diagnosis, Differential; Female; Heart Neoplasms; Heart Valve Diseases; Heptanoic Acids; Humans; Hypertension; Mitral Valve; Monitoring, Physiologic; Platelet Aggregation Inhibitors; Pyrroles; Quinapril; Radiography; Tetrahydroisoquinolines; Treatment Outcome | 2014 |
Robust and enduring atorvastatin-mediated memory recovery following the 4-vessel occlusion/internal carotid artery model of chronic cerebral hypoperfusion in middle-aged rats.
Topics: Aging; Amnesia, Retrograde; Animals; Atorvastatin; Brain; Cerebrovascular Disorders; Chronic Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Maze Learning; Memory; Nootropic Agents; Pyramidal Cells; Rats, Wistar; Treatment Outcome | 2016 |
A non-hypocholesterolemic atorvastatin treatment improves vessel elasticity by acting on elastin composition in WHHL rabbits.
Topics: Aging; Animals; Aorta; Arteries; Atherosclerosis; Atorvastatin; Blood Pressure; Collagen; Disease Models, Animal; Elastic Modulus; Elastin; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pulse Wave Analysis; Rabbits; Stress, Mechanical; Tensile Strength | 2016 |
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin.
Topics: Aging; Animals; Atorvastatin; Calcium; Chloride Channels; Creatine Kinase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; MEF2 Transcription Factors; Muscle, Skeletal; Muscular Atrophy; Protein Kinase C; Rats, Wistar | 2016 |
Amlodipine and atorvastatin improve ventricular hypertrophy and diastolic function via inhibiting TNF-α, IL-1β and NF-κB inflammatory cytokine networks in elderly spontaneously hypertensive rats.
Topics: Aging; Amlodipine; Animals; Atorvastatin; C-Reactive Protein; Cardiomegaly; Diastole; Heart Ventricles; I-kappa B Proteins; Inflammation; Interleukin-1beta; Male; Myocardium; NF-kappa B; Rats, Inbred SHR; Rats, Inbred WKY; Tumor Necrosis Factor-alpha | 2016 |
Additive beneficial effects of amlodipine and atorvastatin in reversing advanced cardiac hypertrophy in elderly spontaneously hypertensive rats.
Topics: Aging; Amlodipine; Animals; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Cardiomegaly; Drug Synergism; Drug Therapy, Combination; Fibrosis; Heart Failure, Diastolic; Hemodynamics; Heptanoic Acids; Myocytes, Cardiac; NADPH Oxidases; Natriuretic Peptide, Brain; Oxidative Stress; Pyrroles; Random Allocation; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Superoxide Dismutase; Ventricular Dysfunction, Left | 2009 |
Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs.
Topics: Aging; Amyloid beta-Peptides; Animals; Anticholesteremic Agents; Atorvastatin; Cholesterol; Cognition; Discrimination Learning; Dogs; Female; Heptanoic Acids; Male; Protein Processing, Post-Translational; Psychomotor Performance; Pyrroles; Random Allocation; Time Factors | 2010 |
Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Atorvastatin; Body Weight; Brain; Cognition Disorders; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Maze Learning; Mice; Mice, Transgenic; Neuroprotective Agents; Organ Size; Phosphorylation; Plaque, Amyloid; Protein Processing, Post-Translational; Pyrroles; Quinolines; tau Proteins | 2011 |
Atorvastatin prevents age-related and amyloid-β-induced microglial activation by blocking interferon-γ release from natural killer cells in the brain.
Topics: Aging; Amyloid beta-Peptides; Animals; Anticholesteremic Agents; Atorvastatin; Biomarkers; Brain; Heptanoic Acids; Interferon-gamma; Killer Cells, Natural; Male; Microglia; Natural Cytotoxicity Triggering Receptor 1; NK Cell Lectin-Like Receptor Subfamily B; Pyrroles; Rats; Rats, Wistar | 2011 |
[The effects of atorvastatin on aging kidney].
Topics: Aging; Animals; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Female; Heptanoic Acids; Kidney; Kidney Diseases; Pyrroles; Rats; Rats, Wistar; Renal Artery | 2011 |
Coenzyme Q10 and cognition in atorvastatin treated dogs.
Topics: Aging; Animals; Atorvastatin; Cognition Disorders; Dogs; Female; Heptanoic Acids; Male; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; Parietal Lobe; Pyrroles; Ubiquinone | 2011 |
Atorvastatin may delay cardiac aging by upregulating peroxisome proliferator-activated receptors in rats.
Topics: Aging; Animals; Anticholesteremic Agents; Atorvastatin; Blood Pressure; Cells, Cultured; Gene Expression Regulation; Heart; Heptanoic Acids; Inflammation Mediators; Myocardium; Oxidoreductases; Peroxisome Proliferator-Activated Receptors; Pyrroles; Rats; Rats, Wistar; Up-Regulation | 2012 |
[Protective effect of atrovastatin against myocardial ischemia-reperfusion injury and on liver and kidney functions in aged rats].
Topics: Aging; Animals; Atorvastatin; Female; Heptanoic Acids; Kidney; Liver; Male; Multiple Organ Failure; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyrroles; Rats; Rats, Wistar | 2012 |
Improvement of arterial stiffness by reducing oxidative stress damage in elderly hypertensive patients after 6 months of atorvastatin therapy.
Topics: Age Factors; Aged; Aged, 80 and over; Aging; Anticholesteremic Agents; Arteries; Atorvastatin; Biomarkers; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Prospective Studies; Pyrroles; Statistics as Topic; Statistics, Nonparametric | 2012 |
Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats.
Topics: Actins; Aging; Animals; Apoptosis; Atorvastatin; beta-Galactosidase; Cell Proliferation; Collagen; Connective Tissue Growth Factor; Desmin; Dose-Response Relationship, Drug; Flow Cytometry; Hepatic Stellate Cells; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Cirrhosis; Male; Myofibroblasts; Pyrroles; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2012 |
Effect of atorvastatin on impaired vascular function in healthy old men.
Topics: Acetylcholine; Adult; Aged; Aged, 80 and over; Aging; Anticholesteremic Agents; Atorvastatin; Brachial Artery; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Endothelium, Vascular; Forearm; Heptanoic Acids; Humans; Male; Nitroprusside; Plethysmography; Pyrroles; Reference Values; Regional Blood Flow; Serotonin; Triglycerides; Vasodilation; Vasodilator Agents | 2004 |
Atorvastatin reverses age-related reduction in rat hepatic PPARalpha and HNF-4.
Topics: Aging; Animals; Anticholesteremic Agents; Atorvastatin; Blood Glucose; Cholesterol Esters; Diet; DNA-Binding Proteins; Fatty Acids, Nonesterified; Female; Gene Expression Regulation; Heptanoic Acids; Lipid Metabolism; Liver; Liver X Receptors; Male; Orphan Nuclear Receptors; PPAR alpha; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sex Factors; Triglycerides | 2005 |
Atorvastatin slows down the deterioration of inner ear function with age in mice.
Topics: Acoustic Stimulation; Aging; Animals; Apolipoproteins E; Atorvastatin; Auditory Threshold; Dose-Response Relationship, Radiation; Ear, Inner; Food, Formulated; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred C57BL; Mice, Knockout; Otoacoustic Emissions, Spontaneous; Presbycusis; Pyrroles; Receptors, Vasopressin; Time Factors | 2007 |