Page last updated: 2024-08-24

atorvastatin and Adverse Drug Event

atorvastatin has been researched along with Adverse Drug Event in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (32.14)29.6817
2010's12 (42.86)24.3611
2020's7 (25.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
El Hamdaoui, H; Elens, L; Haufroid, V; Horion, S; Hoste, E; Muccioli, GG; Panin, N; Paquot, A1
Chen, NN; Li, JX; Ma, XD; Su, SW; Wang, CC; Wang, KX; Wu, YZ; Xiong, C1
Li, XY; Mao, YM; Zhong, W1
Adams, SP; Alaeiilkhchi, N; Tasnim, S; Wright, JM1
Patrono, C; Pedicino, D1
Hale, G; Lyver, E; Stein, B; Ward, T1
Armitage, J; Beaumont, D; Brack, K; Goldacre, B; Herrett, E; MacDonald, T; Prowse, D; Roberts, I; Shakur-Still, H; Smeeth, L; Staa, TV; Williamson, E; Youssouf, N1
Garcia, B; Halvorsen, KH; Samdal, H; Svendsen, K; Vorren, S1
Bohn, JM; Connolly, JG; Desai, RJ; Fischer, MA; Gagne, JJ; Kesselheim, AS; Khan, NF; Rogers, JR; Sarpatwari, A1
Baggett, MC; Nykamp, D1
Hunter, ML; Mahvan, TD; Mlodinow, SG; Onysko, MK; Vandiver, JW1
Božina, N; Ganoci, L; Macolić Šarinić, V; Mirošević Skvrce, N; Muačević Katanec, D; Šimić, I1
Dhopeshwarkar, N; Goss, F; Lai, K; Rozenblum, R; Sa'adon, R; Seger, DL; Topaz, M; Zhou, L1
Bao, W; Chan, JC; Fayyad, R; Kong, AP; Laskey, R1
Audenrode, MV; Cremieux, P; Duh, MS; Greenberg, P; Karner, P; Vekeman, F; Zhang, H1
Agnew-Blais, J; Choudhry, NK; Parker, RM; Shekelle, P; Shrank, WH; Wolf, MS1
Jewells, V; Markovic-Plese, S; Speer, D1
Kukes, IV; Paukov, SV; Ruvinov, IuV; Sivkov, AS1
Becker, ML; Elens, LL; Hofman, A; Stricker, BH; Uitterlinden, AG; van Schaik, RH; Visser, LE1
Cassels, A; Cole, C; Hughes, MA; Lexchin, J; McCormack, JP; Mintzes, B1
Cárcamo, CA; Celedón, C; Nygren, CE; Paulós, CP1
Guthrie, RM1
McHugh, A1
Andrade, RJ; Barriocanal, A; Borraz, Y; Costa, J; Durán, JA; Fernández, MC; García-Cortés, M; García-Muņoz, B; Guarner, C; Hidalgo, R; Kaplowitz, N; Lucena, MI; Muņoz-Yagüe, T; Pachkoria, K; Pelaez, G; Planas, R; Rodrigo, L; Romero-Gomez, M; Salmerón, J1
Hanson, ML; Kelly, SE; Richards, SM1

Reviews

2 review(s) available for atorvastatin and Adverse Drug Event

ArticleYear
Pravastatin for lowering lipids.
    The Cochrane database of systematic reviews, 2023, 09-18, Volume: 9

    Topics: Atorvastatin; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Drug-Related Side Effects and Adverse Reactions; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infant; Infant, Newborn; Pravastatin; Rosuvastatin Calcium

2023
How safe is aggressive statin therapy?
    Progress in cardiovascular nursing, 2006,Summer, Volume: 21, Issue:3

    Topics: Atorvastatin; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Muscular Diseases; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2006

Trials

2 trial(s) available for atorvastatin and Adverse Drug Event

ArticleYear
Study protocol for statin web-based investigation of side effects (StatinWISE): a series of randomised controlled N-of-1 trials comparing atorvastatin and placebo in UK primary care.
    BMJ open, 2017, Dec-01, Volume: 7, Issue:12

    Topics: Atorvastatin; Cardiovascular Diseases; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Medicine; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Muscular Diseases; Primary Health Care; Randomized Controlled Trials as Topic; Treatment Outcome; United Kingdom

2017
Impact of a pharmaceutical care program in a community pharmacy on patients with dyslipidemia.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:5

    Topics: Aged; Atorvastatin; Chile; Community Pharmacy Services; Drug-Related Side Effects and Adverse Reactions; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Male; Middle Aged; Patient Compliance; Patient Education as Topic; Patient Satisfaction; Pyrroles; Quality of Life

2005

Other Studies

24 other study(ies) available for atorvastatin and Adverse Drug Event

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Genetic Polymorphisms in SLCO2B1 and ABCC1 Conjointly Modulate Atorvastatin Intracellular Accumulation in HEK293 Recombinant Cell Lines.
    Therapeutic drug monitoring, 2023, 06-01, Volume: 45, Issue:3

    Topics: Atorvastatin; Chromatography, Liquid; Drug-Related Side Effects and Adverse Reactions; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Polymorphism, Single Nucleotide; Tandem Mass Spectrometry

2023
Therapeutic effects of atorvastatin on doxorubicin-induced hepatotoxicity in rats via antioxidative damage, anti-inflammatory, and anti-lipotoxicity.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Atorvastatin; Chemical and Drug Induced Liver Injury; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Oxidative Stress; Rats

2023
[Statin-related drug-induced liver injury].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2023, Jun-20, Volume: 31, Issue:6

    Topics: Atorvastatin; Chemical and Drug Induced Liver Injury; Drug-Related Side Effects and Adverse Reactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Simvastatin

2023
Adverse effects of anthracyclines: does atorvastatin STOP-CArdiotoxicity?
    European heart journal, 2023, 11-14, Volume: 44, Issue:43

    Topics: Anthracyclines; Antibiotics, Antineoplastic; Atorvastatin; Cardiotoxicity; Drug-Related Side Effects and Adverse Reactions; Humans; Neoplasms

2023
Safety of High-Intensity Statins in the Veteran Population: Atorvastatin 40 to 80 mg Compared With Rosuvastatin 20 to 40 mg.
    The Annals of pharmacotherapy, 2020, Volume: 54, Issue:5

    Topics: Aged; Atherosclerosis; Atorvastatin; Cohort Studies; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Medication Adherence; Middle Aged; Odds Ratio; Retrospective Studies; Rosuvastatin Calcium; Veterans

2020
Adverse drug reaction reporting: how can drug consumption information add to analyses using spontaneous reports?
    European journal of clinical pharmacology, 2018, Volume: 74, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Atorvastatin; Central Nervous System Stimulants; Databases, Factual; Drug Utilization Review; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Methylphenidate; Norway; Pharmaceutical Services; Pharmacovigilance; Risk Factors; Sex Factors; Simvastatin

2018
Effect of Lawyer-Submitted Reports on Signals of Disproportional Reporting in the Food and Drug Administration's Adverse Event Reporting System.
    Drug safety, 2019, Volume: 42, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Atorvastatin; Dermatologic Agents; Drug-Related Side Effects and Adverse Reactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isotretinoin; Lawyers; Rosuvastatin Calcium; United States; United States Food and Drug Administration

2019
Statin-Associated Bilateral Foot Myopathy.
    Journal of pharmacy practice, 2020, Volume: 33, Issue:6

    Topics: Adult; Atorvastatin; Drug-Related Side Effects and Adverse Reactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Muscular Diseases; Rhabdomyolysis

2020
Statin adverse effects: sorting out the evidence.
    The Journal of family practice, 2014, Volume: 63, Issue:9

    Topics: Atorvastatin; Clinical Trials as Topic; Drug Monitoring; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Practice; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Outcome Assessment, Health Care; Practice Guidelines as Topic; Pyrroles; Rhabdomyolysis; Risk Adjustment; Ubiquinone; Vitamins

2014
ABCG2 gene polymorphisms as risk factors for atorvastatin adverse reactions: a case-control study.
    Pharmacogenomics, 2015, Volume: 16, Issue:8

    Topics: Adult; Asian People; Atorvastatin; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cytochrome P-450 CYP3A; Drug-Related Side Effects and Adverse Reactions; Female; Genetic Association Studies; Genotype; Humans; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Neoplasm Proteins; Organic Anion Transporters; Polymorphism, Single Nucleotide; Risk Factors

2015
Clinicians' Reports in Electronic Health Records Versus Patients' Concerns in Social Media: A Pilot Study of Adverse Drug Reactions of Aspirin and Atorvastatin.
    Drug safety, 2016, Volume: 39, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Aspirin; Atorvastatin; Drug-Related Side Effects and Adverse Reactions; Electronic Health Records; Exanthema; Humans; Musculoskeletal Pain; Physician's Role; Pilot Projects; Social Media

2016
Safety of atorvastatin in Asian patients within clinical trials.
    Cardiovascular therapeutics, 2016, Volume: 34, Issue:6

    Topics: Aged; Asia; Asian People; Atorvastatin; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Patient Safety; Patient Selection; Randomized Controlled Trials as Topic; Research Subjects; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome

2016
Can social media data lead to earlier detection of drug-related adverse events?
    Pharmacoepidemiology and drug safety, 2016, Volume: 25, Issue:12

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Atorvastatin; Cyclobutanes; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Middle Aged; Pharmacovigilance; Social Media; Time Factors; United States; United States Food and Drug Administration

2016
Variability in pharmacy interpretations of physician prescriptions.
    Medical care, 2009, Volume: 47, Issue:3

    Topics: Alendronate; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Atorvastatin; Bone Density Conservation Agents; Comprehension; Contraindications; Drug Information Services; Drug Labeling; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Education, Pharmacy; Educational Status; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ibuprofen; Patient Education as Topic; Pharmaceutical Preparations; Pharmacies; Professional Competence; Pyrroles; Trimethoprim, Sulfamethoxazole Drug Combination; Urban Health Services; Writing

2009
Combining beta interferon and atorvastatin may increase disease activity in multiple sclerosis.
    Neurology, 2009, Jun-02, Volume: 72, Issue:22

    Topics: Anticholesteremic Agents; Atorvastatin; Central Nervous System; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Heptanoic Acids; Humans; Iatrogenic Disease; Immunologic Factors; Interferon-beta; Multiple Sclerosis; Pyrroles; Risk Assessment

2009
[Individual pharmacotherapy safety in the assessment of cytochrome P-450 3A4 (CYP3A4) isoenzyme activity].
    Klinicheskaia meditsina, 2010, Volume: 88, Issue:2

    Topics: Atorvastatin; Clinical Trials as Topic; Clopidogrel; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Pharmacokinetics; Platelet Aggregation Inhibitors; Precision Medicine; Pyrroles; Ticlopidine

2010
Genetic variation in the ABCC2 gene is associated with dose decreases or switches to other cholesterol-lowering drugs during simvastatin and atorvastatin therapy.
    The pharmacogenomics journal, 2013, Volume: 13, Issue:3

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Genetic Association Studies; Haplotypes; Heptanoic Acids; Humans; Male; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Polymorphism, Single Nucleotide; Proportional Hazards Models; Pyrroles; Simvastatin

2013
Drugs in the news: an analysis of Canadian newspaper coverage of new prescription drugs.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003, Apr-29, Volume: 168, Issue:9

    Topics: Acetamides; Advertising; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antiviral Agents; Atorvastatin; Bibliometrics; Canada; Celecoxib; Cholinesterase Inhibitors; Consumer Product Safety; Disclosure; Donepezil; Drug Industry; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Estrogen Antagonists; Heptanoic Acids; Humans; Indans; Newspapers as Topic; Oseltamivir; Patient Education as Topic; Piperidines; Pyrazoles; Pyrroles; Raloxifene Hydrochloride; Sulfonamides

2003
Fake drugs: a problem for all.
    British journal of hospital medicine (London, England : 2005), 2006, Volume: 67, Issue:10

    Topics: Atorvastatin; Drug Industry; Drug-Related Side Effects and Adverse Reactions; Fraud; Heptanoic Acids; Humans; Pyrroles

2006
Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Atorvastatin; Azepines; Captopril; Cardiovascular Agents; Central Nervous System Agents; Chemical and Drug Induced Liver Injury; Chronic Disease; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Heptanoic Acids; Humans; Liver; Liver Diseases; Male; Middle Aged; Pyrroles; Registries; Spain

2006
Zooplankton chitobiase activity as an endpoint of pharmaceutical effect.
    Archives of environmental contamination and toxicology, 2008, Volume: 54, Issue:4

    Topics: Acetylglucosaminidase; Animals; Atorvastatin; Biological Assay; Daphnia; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Environmental Monitoring; Fluoxetine; Heptanoic Acids; Lethal Dose 50; Lovastatin; Pyrroles; Sertraline; Water Pollutants, Chemical; Xenobiotics; Zooplankton

2008