Page last updated: 2024-08-25

atipamezole and Anesthesia

atipamezole has been researched along with Anesthesia in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	22 (29.73)	18.2507
2000's	27 (36.49)	29.6817
2010's	20 (27.03)	24.3611
2020's	5 (6.76)	2.80

Authors

Authors	Studies
Cheng, AJ; Garbin, M; Lutevele, N; Malo, A; Marangoni, S; Monteiro, BP; Ruel, HL; Steagall, PV; Watanabe, R	1
Adam, M; Hautajärvi, HJ; Honkavaara, JM; Kallio-Kujala, IJ; Larenza Menzies, P; Männikkö, SK; Nevanperä, K; Raekallio, MR; Restitutti, F; Scheinin, M; Turunen, H; Vainio, OM	1
Kamio, K; Kashimoto, J; Shibuta, H; Suda, A; Yamana, R	1
Iba, Y; Kimura, T; Murai, H; Suzuki, H; Tanji, H	1
Dupont, WD; Finnie, KR; Jones, CP; Salleng, KJ; Shuster, KA	1
Cushing, AC; McEntire, MS; Price, J; Ramsay, EC	1
Janssen, CF; Kracinovsky, KB; Maiello, P; Newsome, JT; Wright, MJ	1
Hayek, LC; Marker, L; Murray, S; Sanchez, CR; Woc Colburn, AM	1
Dantsuka, A; Elewa, YHA; Hattori, H; Ichii, O; Karakida, N; Kon, Y; Nagasaki, KI; Nakamura, T; Yoshiyasu, T	1
Greenberg, M; Rama, A; Zuba, JR	1
Dantsuka, A; Hosotani, M; Ichii, O; Irie, T; Kon, Y; Kouguchi, H; Nagasaki, KI; Nakamura, S; Nakamura, T; Sato, S; Sotozaki, K; Yoshiyasu, T	1
Ambrosini, F; Carvalho, ER; Champion, T; D'Otaviano de Castro Vilani, RG; da Silva, GA; Freitas, GC	1
Campoy, L; Martin-Flores, M; Parry, S; Sakai, DM; Zatroch, KK	1
Mikaelian, I; Singer, L; Wellington, D	1
Hikasa, Y; Ueoka, N	2
Izer, JM; Whitcomb, TL; Wilson, RP	1
Arnemo, JM; Caulkett, N; Fahlman, Å; Ozeki, LM; Stenhouse, G	1
Bonarrigo, T; Di Pietro, S; Giudice, E; Macrì, F; Palumbo Piccionello, A; Pugliese, A	1
Buisman, M; Gunn, M; Hasiuk, MMM; Pang, DSJ	1
El Bahri, L	1
Muir, WW; Ueyama, Y; Ueyema, Y; Waselau, AC; Wiese, AJ	1
Andersson, KE; Santti, R; Streng, T	1
Berry, K; Bouts, T; Gasthuys, F; Harrison, N; Routh, A; Taylor, P	1
Bauquier, SH; Hinshaw, KC; Ialeggio, DM; Montgomery, CL; Perkowski, SZ	1
Alves, HN; Antunes, LM; da Silva, AL; Olsson, IA; Orden, JM	1
Bosmans, T; Polis, I; Samoy, Y; Van Ryssen, B; Van Vynckt, D; Verschooten, F	1
Baker, NJ; Caswell, MD; McLellan, AD; Schofield, JC	1
Heaton-Jones, DL; Heaton-Jones, TG; Ko, JC	1
Joubert, KE; Lobetti, R	1
Pinson, DM; Sun, FJ; Wright, DE	1
Bush, M; Lance, W; Phillips, LG; Raath, JP	1
Block, BA; Rollins, M; Williams, TD	1
Jeong, SM; Kim, MS; Nam, TC; Park, JH; Seo, KM	1
Baker, SE; Buesching, CD; Johnson, DD; Johnson, PJ; Macdonald, DW; Newman, C; Slater, D; Thornton, PD	1
Eisen, L; Eisen, RJ; Hahn, N; Lane, RS	1
Carroll, GL; Champney, TH; Geller, SC; Haley, EL; Hartsfield, SM; Martinez, EA	1
Hofkes, LM; Hoyer, MJ; Overgaauw, PA; van Dijk, P	1
Haapalinna, A; Pertovaara, A; Sirviö, J; Virtanen, R	1
Arnemo, JM; Fahlman, A; Foggin, C; Loveridge, A; Nyman, G; Wenham, C	1
Aarhaug, P; Arnemo, JM; Bauer, H; Enriquez, B; Jacquier, M	1
Aspegrén, JC; Granholm, M; McKusick, BC; Westerholm, FC	1
Haydon, T; Kitao, T; Ko, JC; Payton, M; Weil, AB	1
Campbell, M; Crognale, MA; Eckert, SA; Harms, CA; Kubis, SA; Levenson, DH	1
Abbo, LA; Johnson, BM; Ko, JC; Payton, M; Weil, AB	1
Baumgartner, C; Ebner, J; Erhardt, W; Henke, J; Wehr, U	1
Niekrasz, MA; Reed, DA; Theriault, BR	1
Bednarczyk, JM; Weinger, MB	1
Adams, SJ	1
Constantinou, CE; Harada, T	1
Ewing, KK; Mohammed, HO; Scarlett, JM; Short, CE	1
Petcho, A; Verstegen, J	1
Castillo-Olivares, JL; Mascías, A; San Román, F; Santos, M; Segura, IA; Tendillo, FJ	1
de Lange, S; Prinzen, FW; Roekaerts, PM	1
Burzaco, OH; Cruz, JI; Loste, JM	1
Benson, GJ; Grimm, KA; Olson, WA; Thurmon, JC; Tranquilli, WJ	1
De Thoisy, B; Fournier, P; Fournier-Chambrillon, C; Genty, C; Kéravec, J; Vié, JC	1
de Thoisy, B; Vié, JC; Vogel, I	1
Talke, P	1
Baertschi, AJ; Grubb, MC; Guyenet, PG; Pence, R; Stornetta, RL	1
Citino, SB; Deem, SL; Ko, JC	1
Cattet, MR; Caulkett, NA; Polischuk, SC; Ramsay, MA	1
Buchner, HH; Kübber, P; Peham, C; Zohmann, E	1
Ritacco, G; Schilling, AM; Skeans, S; Young, SS	1
Haupt, MA; Meltzer, DG; Nel, PJ; Taylor, A	1
Flecknell, PA; Hedenqvist, P; Roughan, JV	1
Harvey, RC; Jones, MP; Langan, JN; Orosz, SE; Pollock, C; Schumacher, J	1
Diggs, HE; Greer, LL; Jenne, KJ	1
Hayes, KE; Taylor, R; Toth, LA	1
Jyväsjärvi, E; Kauppila, T; Pertovaara, A	1
Dickenson, AH; Kalso, EA; McQuay, HJ; Sullivan, AF	1
Flecknell, PA; Hu, C; Liles, JH	1
Kauppila, T; Kemppainen, P; Pertovaara, A	1
Donnay, I; Ectors, F; Fargetton, X; Verstegen, J; Zanker, S	1

Reviews

2 review(s) available for atipamezole and Anesthesia

Article	Year
Atipamezole. Compendium (Yardley, PA), 2008, Volume: 30, Issue:5 Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Imidazoles; Legislation, Drug; Lethal Dose 50; Veterinary Drugs	2008
Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist. CNS drug reviews, 2005,Autumn, Volume: 11, Issue:3 Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Central Nervous System Agents; Cognition Disorders; Emotions; Epilepsy; Humans; Imidazoles; Pain; Parkinson Disease; Receptors, Adrenergic, alpha-2; Sexual Behavior	2005

Article

Year

Atipamezole.

Compendium (Yardley, PA), 2008, Volume: 30, Issue:5

Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Imidazoles; Legislation, Drug; Lethal Dose 50; Veterinary Drugs

2008

Pharmacological properties, central nervous system effects, and potential therapeutic applications of atipamezole, a selective alpha2-adrenoceptor antagonist.

CNS drug reviews, 2005,Autumn, Volume: 11, Issue:3

Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Central Nervous System Agents; Cognition Disorders; Emotions; Epilepsy; Humans; Imidazoles; Pain; Parkinson Disease; Receptors, Adrenergic, alpha-2; Sexual Behavior

2005

Trials

14 trial(s) available for atipamezole and Anesthesia

Article	Year
Randomised, prospective, blinded, clinical trial of opioid-free injectable anaesthesia with or without multimodal analgesia in kittens undergoing ovariohysterectomy. Journal of feline medicine and surgery, 2023, Volume: 25, Issue:3 Topics: Analgesics, Opioid; Anesthesia; Animals; Bupivacaine; Cats; Dexmedetomidine; Eating; Female; Hysterectomy; Injections, Intramuscular; Ketamine; Meloxicam; Midazolam; Ovariectomy; Pain Measurement; Pain, Postoperative; Single-Blind Method	2023
Cardiovascular and sedation reversal effects of intramuscular administration of atipamezole in dogs treated with medetomidine hydrochloride with or without the peripheral α American journal of veterinary research, 2019, Volume: 80, Issue:10 Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Cardiac Output; Cardiovascular System; Cross-Over Studies; Dexmedetomidine; Dogs; Heart Rate; Hemodynamics; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Male; Medetomidine; Quinolizines; Random Allocation; Single-Blind Method	2019
A Comparison of the Efficacy and Cardiopulmonary Effects of 3 Different Sedation Protocols in Journal of the American Association for Laboratory Animal Science : JAALAS, 2020, 09-01, Volume: 59, Issue:5 Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Anesthetics; Animals; Blood Pressure; Dexmedetomidine; Female; Galagidae; Heart Rate; Hypnotics and Sedatives; Imidazoles; Ketamine; Male; Pregnanediones	2020
Comparison of Atipamezole with Yohimbine for Antagonism of Xylazine in Mice Anesthetized with Ketamine and Xylazine. Journal of the American Association for Laboratory Animal Science : JAALAS, 2017, Mar-01, Volume: 56, Issue:2 Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Anesthesia; Animals; Cross-Over Studies; Imidazoles; Ketamine; Laboratory Animal Science; Male; Mice; Xylazine; Yohimbine	2017
CARDIORESPIRATORY EFFECTS OF DEXMEDETOMIDINE-BUTORPHANOL-MIDAZOLAM (DBM): A FULLY REVERSIBLE ANESTHETIC PROTOCOL IN CAPTIVE AND SEMI-FREE-RANGING CHEETAHS (ACINONYX JUBATUS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2017, Volume: 48, Issue:1 Topics: Acinonyx; Analgesics, Opioid; Anesthesia; Animals; Animals, Zoo; Butorphanol; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Male; Midazolam; Naltrexone; Respiration	2017
Evaluation of atipamezole as a treatment for dexmedetomidine-induced cardiovascular depression in anesthetized cats. American journal of veterinary research, 2019, Volume: 80, Issue:5 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Cardiac Output; Cats; Cross-Over Studies; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Imidazoles; Isoflurane; Male; Random Allocation; Vascular Resistance	2019
Effects of a medetomidine-ketamine combination on Schirmer tear test I results of clinically normal cats. American journal of veterinary research, 2016, Volume: 77, Issue:3 Topics: Anesthesia; Anesthetics, Dissociative; Animals; Cats; Drug Combinations; Female; Hypnotics and Sedatives; Imidazoles; Ketamine; Male; Medetomidine; Tears	2016
Preliminary comparison of four anaesthetic techniques in badgers (Meles meles). Veterinary anaesthesia and analgesia, 2005, Volume: 32, Issue:1 Topics: Adjuvants, Anesthesia; Adrenergic alpha-Antagonists; Analgesics; Anesthesia; Animals; Female; Imidazoles; Injections, Intramuscular; Ketamine; Male; Medetomidine; Midazolam; Mustelidae; Prospective Studies; Treatment Outcome	2005
Effect of medetomidine and its antagonism with atipamezole on stress-related hormones, metabolites, physiologic responses, sedation, and mechanical threshold in goats. Veterinary anaesthesia and analgesia, 2005, Volume: 32, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Blood Glucose; Blood Pressure; Body Temperature; Drug Interactions; Epinephrine; Female; Goats; Heart Rate; Hydrocortisone; Imidazoles; Infusions, Intravenous; Male; Medetomidine; Norepinephrine; Prospective Studies; Respiration	2005
Evaluation of the clinical efficacy and safety of intramuscular and intravenous doses of dexmedetomidine and medetomidine in dogs and their reversal with atipamezole. The Veterinary record, 2007, Jun-30, Volume: 160, Issue:26 Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Body Temperature; Dexmedetomidine; Dogs; Drug Administration Routes; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Male; Medetomidine; Respiration; Time Factors	2007
Comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-butorphanol and tiletamine-zolazepam-butorphanol-medetomidine in dogs. Veterinary therapeutics : research in applied veterinary medicine, 2007,Summer, Volume: 8, Issue:2 Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Blood Pressure; Butorphanol; Cross-Over Studies; Dogs; Female; Glycopyrrolate; Heart Rate; Hypoxia; Imidazoles; Injections, Intramuscular; Male; Medetomidine; Narcotics; Respiration; Tiletamine; Time Factors; Treatment Outcome; Xylazine; Zolazepam	2007
A comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-butorphanol and tiletamine-zolazepam-butorphanol- medetomidine in cats. Veterinary therapeutics : research in applied veterinary medicine, 2007,Fall, Volume: 8, Issue:3 Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Blood Pressure; Butorphanol; Cats; Cross-Over Studies; Female; Glycopyrrolate; Heart Rate; Imidazoles; Injections, Intramuscular; Male; Medetomidine; Narcotics; Respiration; Tiletamine; Time Factors; Treatment Outcome; Xylazine; Zolazepam	2007
Reduction of isoflurane anesthetic requirement by medetomidine and its restoration by atipamezole in dogs. American journal of veterinary research, 1993, Volume: 54, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Blood Pressure; Dogs; Female; Heart Rate; Imidazoles; Isoflurane; Medetomidine	1993
Sedation and antisedation as tools in equine lameness examination. Equine veterinary journal. Supplement, 1999, Issue:30 Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Biomechanical Phenomena; Female; Gait; Horse Diseases; Horses; Hypnotics and Sedatives; Imidazoles; Lameness, Animal; Male; Physical Examination	1999

Other Studies

58 other study(ies) available for atipamezole and Anesthesia

Article	Year
Comparison of the anesthetic effect by the injection route of mixed anesthesia (medetomidine, midazolam and butorphanol) and the effect of this anesthetic agent on the respiratory function. The Journal of veterinary medical science, 2020, Jan-10, Volume: 82, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Anesthesia; Anesthetics, Combined; Animals; Blood Gas Analysis; Butorphanol; Hypnotics and Sedatives; Imidazoles; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Medetomidine; Midazolam; Rats, Sprague-Dawley; Respiration	2020
A simple method using anesthetics to test effects of sleep-inducing substances in mice. Journal of pharmacological sciences, 2020, Volume: 142, Issue:2 Topics: Anesthesia; Anesthetics; Animals; Azepines; Butorphanol; Chlorpromazine; Drug Combinations; Imidazoles; Indenes; Isoflurane; Male; Medetomidine; Mice; Mice, Inbred ICR; Midazolam; Orexin Receptor Antagonists; Sleep Aids, Pharmaceutical; Triazoles	2020
THE EFFECTS OF PROCEDURE DURATION AND ATIPAMEZOLE ADMINISTRATION ON HYPERKALEMIA IN TIGERS ( Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2020, Volume: 51, Issue:3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Animals, Zoo; Female; Hyperkalemia; Imidazoles; Lions; Male; Retrospective Studies; Tigers	2020
Effects of a mixture of medetomidine, midazolam and butorphanol on anesthesia and blood biochemistry and the antagonizing action of atipamezole in hamsters. The Journal of veterinary medical science, 2017, Jul-19, Volume: 79, Issue:7 Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Anesthetics, Combined; Animals; Butorphanol; Calcium; Dose-Response Relationship, Drug; Imidazoles; Injections, Intramuscular; Male; Medetomidine; Mesocricetus; Midazolam; Phosphorus; Sodium	2017
Atipamezole as an emergency treatment for overdose from highly concentrated alpha-2 agonists used in zoo and wildlife anesthesia. The American journal of emergency medicine, 2018, Volume: 36, Issue:1 Topics: Accidents, Occupational; Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Animals, Zoo; Clinical Protocols; Dose-Response Relationship, Drug; Drug Overdose; Emergency Treatment; Humans; Imidazoles; Veterinary Medicine	2018
Usefulness of an anesthetic mixture of medetomidine, midazolam, and butorphanol in cotton rats (Sigmodn hispidus). The Japanese journal of veterinary research, 2016, Volume: 64, Issue:4 Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics, Opioid; Anesthesia; Anesthetics, Combined; Animals; Butorphanol; Female; Hypnotics and Sedatives; Imidazoles; Male; Medetomidine; Midazolam; Sigmodontinae	2016
Dexmedetomidine low dose followed by constant rate infusion and antagonism by atipamezole in isoflurane-anesthetized cats: an echocardiographic study. Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:1 Topics: Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Cats; Cohort Studies; Dexmedetomidine; Echocardiography; Heart Rate; Hypnotics and Sedatives; Imidazoles; Infusions, Intravenous; Isoflurane; Male; Orchiectomy; Prospective Studies	2019
Comparison of ketamine-xylazine and ketamine-dexmedetomidine anesthesia and intraperitoneal tolerance in rats. Journal of the American Association for Laboratory Animal Science : JAALAS, 2013, Volume: 52, Issue:4 Topics: Anesthesia; Anesthetics; Animals; Dexmedetomidine; Drug Therapy, Combination; Heart Rate; Imidazoles; Injections, Intraperitoneal; Ketamine; Male; Rats; Rats, Wistar; Xylazine	2013
Effects in cats of atipamezole, flumazenil and 4-aminopyridine on stress-related neurohormonal and metabolic responses induced by medetomidine, midazolam and ketamine. Journal of feline medicine and surgery, 2015, Volume: 17, Issue:8 Topics: 4-Aminopyridine; Anesthesia; Anesthetics, Combined; Animals; Arousal; Cats; Dose-Response Relationship, Drug; Flumazenil; Imidazoles; Ketamine; Medetomidine; Midazolam; Respiration	2015
Atipamezole reverses ketamine-dexmedetomidine anesthesia without altering the antinociceptive effects of butorphanol and buprenorphine in female C57BL/6J mice. Journal of the American Association for Laboratory Animal Science : JAALAS, 2014, Volume: 53, Issue:6 Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Anesthesia; Anesthetics; Animals; Buprenorphine; Butorphanol; Dexmedetomidine; Female; Imidazoles; Ketamine; Mice; Mice, Inbred C57BL	2014
EFFECT OF ACTIVE COOLING AND α-2 ADRENOCEPTOR ANTAGONISM ON CORE TEMPERATURE IN ANESTHETIZED BROWN BEARS (URSUS ARCTOS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2015, Volume: 46, Issue:2 Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Animals, Wild; Body Temperature; Fever; Hypnotics and Sedatives; Imidazoles; Immobilization; Medetomidine; Ursidae; Xylazine	2015
The influence of demeanor on scores from two validated feline pain assessment scales during the perioperative period. Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:3 Topics: Anesthesia; Animals; Cats; Dexmedetomidine; Hydromorphone; Imidazoles; Ketamine; Lidocaine; Male; Meloxicam; Orchiectomy; Pain Measurement; Pain, Postoperative; Perioperative Period; Prospective Studies; Thiazines; Thiazoles	2017
Anesthetic and cardiopulmonary effects of intramuscular morphine, medetomidine, ketamine injection in dogs. Veterinary anaesthesia and analgesia, 2008, Volume: 35, Issue:6 Topics: Adrenergic alpha-Antagonists; Analgesia; Anesthesia; Anesthetics; Animals; Dogs; Drug Therapy, Combination; Female; Imidazoles; Ketamine; Male; Medetomidine; Morphine; Time Factors	2008
Voiding effects mediated by α2-adrenoceptors in the anaesthetized male rat. BJU international, 2010, Volume: 106, Issue:10 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Anesthesia; Animals; Dexmedetomidine; Imidazoles; Male; Rats; Urinary Tract; Urination; Urodynamics	2010
Comparison of three anaesthetic protocols in Bennett's wallabies (Macropus rufogriseus). Veterinary anaesthesia and analgesia, 2010, Volume: 37, Issue:3 Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Animals; Blood Gas Analysis; Body Temperature; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Imidazoles; Injections, Intramuscular; Ketamine; Macropodidae; Male; Medetomidine; Respiratory Rate; Xylazine	2010
Reversible immobilization of giant otters (Pteronura brasiliensis) using medetomidine-ketamine and atipamezole. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2010, Volume: 41, Issue:2 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Dissociative; Animals; Dose-Response Relationship, Drug; Female; Hypnotics and Sedatives; Imidazoles; Immobilization; Ketamine; Male; Medetomidine; Otters	2010
Anesthesia with intraperitoneal propofol, medetomidine, and fentanyl in rats. Journal of the American Association for Laboratory Animal Science : JAALAS, 2010, Volume: 49, Issue:4 Topics: Anesthesia; Anesthetics; Animals; Fentanyl; Imidazoles; Injections, Intraperitoneal; Laboratory Animal Science; Male; Medetomidine; Propofol; Rats; Rats, Wistar	2010
Evaluation of two sedation protocols for use before diagnostic intra-articular anaesthesia in lame dogs. The Journal of small animal practice, 2011, Volume: 52, Issue:12 Topics: Acepromazine; Anesthesia; Animals; Conscious Sedation; Dog Diseases; Dogs; Female; Hypnotics and Sedatives; Imidazoles; Injections, Intra-Articular; Lameness, Animal; Male; Medetomidine; Methadone; Random Allocation	2011
Effects of early atipamezole reversal of medetomidine-ketamine anesthesia in mice. Journal of the American Association for Laboratory Animal Science : JAALAS, 2011, Volume: 50, Issue:6 Topics: Anesthesia; Anesthesia Recovery Period; Animals; Imidazoles; Ketamine; Medetomidine; Mice; Reflex; Time Factors	2011
Evaluation of medetomidine-ketamine anesthesia with atipamezole reversal in American alligators (Alligator mississippiensis). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2002, Volume: 33, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alligators and Crocodiles; Analgesics, Non-Narcotic; Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Electrocardiography; Heart Rate; Imidazoles; Ketamine; Medetomidine; Reflex; Respiration; Restraint, Physical	2002
The cardiovascular and respiratory effects of medetomidine and thiopentone anaesthesia in dogs breathing at an altitude of 1486 m. Journal of the South African Veterinary Association, 2002, Volume: 73, Issue:3 Topics: Adrenergic alpha-Antagonists; Altitude; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Dogs; Drug Interactions; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Male; Medetomidine; Oxygen; Respiration; Thiopental	2002
Comparison of ketamine versus combination of ketamine and medetomidine in injectable anesthetic protocols: chemical immobilization in macaques and tissue reaction in rats. Contemporary topics in laboratory animal science, 2003, Volume: 42, Issue:4 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Anesthesia Recovery Period; Anesthetics, Dissociative; Animals; Behavior, Animal; Drug Therapy, Combination; Imidazoles; Immobilization; Injections, Intramuscular; Ketamine; Macaca mulatta; Male; Medetomidine; Muscle, Skeletal; Rats	2003
Immobilisation of impala (Aepyceros melampus) with a ketamine hydrochloride/medetomidine hydrochloride combination, and reversal with atipamezole hydrochloride. Journal of the South African Veterinary Association, 2004, Volume: 75, Issue:1 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Antelopes; Dose-Response Relationship, Drug; Drug Synergism; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Injections, Intravenous; Ketamine; Male; Medetomidine; Random Allocation	2004
Intramuscular anesthesia of bonito and Pacific mackerel with ketamine and medetomidine and reversal of anesthesia with atipamezole. Journal of the American Veterinary Medical Association, 2004, Aug-01, Volume: 225, Issue:3 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Dissociative; Animals; Dose-Response Relationship, Drug; Drug Combinations; Imidazoles; Injections, Intramuscular; Ketamine; Medetomidine; Perciformes; Random Allocation; Safety; Time Factors	2004
Reversal of medetomidine-ketamine combination anesthesia in rabbits by atipamezole. Experimental animals, 2004, Volume: 53, Issue:5 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Female; Heart Rate; Imidazoles; Ketamine; Male; Medetomidine; Rabbits; Time Factors	2004
Ketamine-medetomidine anesthesia with atipamezole reversal: practical anesthesia for rodents under field conditions. Lab animal, 2005, Volume: 34, Issue:2 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics; Animals; Drug Interactions; Female; Hypnotics and Sedatives; Imidazoles; Ketamine; Male; Medetomidine; Rodentia; Time Factors	2005
[Immobilization of cattle and bison with a combination of xylazine, zolazepam-tiletamine and ketamine]. Tijdschrift voor diergeneeskunde, 2005, May-01, Volume: 130, Issue:9 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Animals; Animals, Domestic; Bison; Blood Gas Analysis; Body Weight; Cattle; Imidazoles; Immobilization; Injections, Intramuscular; Ketamine; Male; Respiration; Tiletamine; Time Factors; Xylazine; Zolazepam	2005
Reversible anaesthesia of free-ranging lions (Panthera leo) in Zimbabwe. Journal of the South African Veterinary Association, 2005, Volume: 76, Issue:4 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Animals, Wild; Blood Pressure; Body Temperature; Dose-Response Relationship, Drug; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Lions; Male; Medetomidine; Respiration; Tiletamine; Time Factors; Zimbabwe; Zolazepam	2005
Reversible immobilization of free-ranging African lions (Panthera leo) with medetomidine-tiletamine-zolazepam and atipamezole. Journal of wildlife diseases, 2006, Volume: 42, Issue:2 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Animals, Wild; Blood Pressure; Body Temperature; Cameroon; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Lions; Male; Medetomidine; Tiletamine; Time Factors; Zolazepam	2006
Field anaesthesia of leatherback sea turtles (Dermochelys coriacea). The Veterinary record, 2007, Jul-07, Volume: 161, Issue:1 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Drug Administration Schedule; Electroretinography; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Infusions, Intravenous; Injections, Intramuscular; Ketamine; Medetomidine; Turtles	2007
Antagonistic effects of atipamezole, flumazenil and 4-aminopyridine against anaesthesia with medetomidine, midazolam and ketamine combination in cats. Journal of feline medicine and surgery, 2008, Volume: 10, Issue:1 Topics: 4-Aminopyridine; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Arousal; Body Temperature; Cats; Dose-Response Relationship, Drug; Flumazenil; Heart Rate; Imidazoles; Injections, Intravenous; Injections, Subcutaneous; Ketamine; Male; Medetomidine; Midazolam	2008
Partial antagonization of midazolam-medetomidine-ketamine in cats--atipamezole versus combined atipamezole and flumazenil. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 2007, Volume: 54, Issue:9 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Heart Rate; Imidazoles; Injections, Intravenous; Injections, Subcutaneous; Ketamine; Male; Medetomidine; Midazolam; Respiration; Time Factors	2007
Reversible medetomidine/ketamine anesthesia in captive capuchin monkeys (Cebus apella). Journal of medical primatology, 2008, Volume: 37 Suppl 1 Topics: Anesthesia; Animals; Biomechanical Phenomena; Cebus; Imidazoles; Ketamine; Male; Mastication; Medetomidine; Restraint, Physical	2008
Atipamezole, an alpha 2 antagonist, augments opiate-induced muscle rigidity in the rat. Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3 Topics: Adrenergic alpha-2 Receptor Antagonists; Alfentanil; Anesthesia; Animals; Dose-Response Relationship, Drug; Electromyography; Imidazoles; Male; Muscle Rigidity; Muscle Tonus; Muscle, Skeletal; Narcotics; Rats; Rats, Wistar	1994
Sedation of exotic species. The Veterinary record, 1994, Aug-06, Volume: 135, Issue:6 Topics: Anesthesia; Anesthetics; Animals; Cebus; Hypnotics and Sedatives; Imidazoles; Ketamine	1994
The effect of alpha 2 agonists and antagonists on the lower urinary tract of the rat. The Journal of urology, 1993, Volume: 149, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Dose-Response Relationship, Drug; Female; Imidazoles; Medetomidine; Rats; Rats, Sprague-Dawley; Urethra; Urinary Bladder; Urination	1993
Medetomidine-butorphanol-midazolam for anaesthesia in dogs and its reversal by atipamezole. The Veterinary record, 1993, Apr-03, Volume: 132, Issue:14 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics; Animals; Butorphanol; Dogs; Drug Combinations; Female; Heart Rate; Hypothermia; Imidazoles; Male; Medetomidine; Midazolam; Muscle Relaxation	1993
Cardiopulmonary and analgesic effects of xylazine, detomidine, medetomidine, and the antagonist atipamezole in isoflurane-anesthetized swine. Laboratory animal science, 1996, Volume: 46, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesia; Analgesics; Anesthesia; Animals; Blood Pressure; Heart; Heart Rate; Imidazoles; Isoflurane; Lung; Medetomidine; Swine; Vascular Resistance; Xylazine	1996
Coronary vascular effects of dexmedetomidine during reactive hyperemia in the anesthetized dog. Journal of cardiothoracic and vascular anesthesia, 1996, Volume: 10, Issue:5 Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Coronary Circulation; Dogs; Female; Hyperemia; Imidazoles; Lactic Acid; Male; Medetomidine; Myocardial Ischemia; Oxygen; Vascular Resistance	1996
Observations on the use of medetomidine/ketamine and its reversal with atipamezole for chemical restraint in the mouse. Laboratory animals, 1998, Volume: 32, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Animals; Body Temperature; Female; Hypnotics and Sedatives; Imidazoles; Immobilization; Ketamine; Male; Medetomidine; Mice; Oximetry; Pilot Projects; Random Allocation	1998
The pharmacodynamics of thiopental, medetomidine, butorphanol and atropine in beagle dogs. Journal of veterinary pharmacology and therapeutics, 1998, Volume: 21, Issue:2 Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Arousal; Atropine; Blood Pressure; Butorphanol; Dogs; Drug Interactions; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Injections, Intravenous; Medetomidine; Thiopental	1998
Anesthesia of wild red howler monkeys (Alouatta seniculus) with medetomidine/ketamine and reversal by atipamezole. American journal of primatology, 1998, Volume: 45, Issue:4 Topics: Alouatta; Anesthesia; Anesthetics, Dissociative; Animals; Body Temperature; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Ketamine; Male; Medetomidine; Respiration	1998
Comparison of injectable anesthetic combinations in free-ranging two-toed sloths in French guiana. Journal of wildlife diseases, 1998, Volume: 34, Issue:3 Topics: Acepromazine; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Combined; Animals; Animals, Wild; Body Temperature; Female; French Guiana; Heart Rate; Hypnotics and Sedatives; Imidazoles; Immobilization; Injections, Intramuscular; Ketamine; Male; Medetomidine; Muscle Relaxation; Oxyhemoglobins; Respiration; Sloths; Tiletamine; Xylazine; Zolazepam	1998
Receptor-specific reversible sedation: beginning of new era of anesthesia? Anesthesiology, 1998, Volume: 89, Issue:3 Topics: Adrenergic alpha-Antagonists; Anesthesia; Humans; Hypnotics and Sedatives; Imidazoles; Medetomidine; Receptors, Adrenergic, alpha	1998
Antagonist precipitated clonidine withdrawal in rat: effects on locus coeruleus neurons, sympathetic nerves and cardiovascular parameters. Journal of the autonomic nervous system, 1998, Jul-15, Volume: 71, Issue:2-3 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Inhalation; Animals; Blood Pressure; Cardiovascular System; Clonidine; Consciousness; Halothane; Heart Rate; Idazoxan; Imidazoles; Locus Coeruleus; Male; Neurons; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Substance Withdrawal Syndrome; Sympathetic Nervous System; Sympatholytics; Vascular Resistance	1998
Anesthetic and cardiorespiratory effects of tiletamine-zolazepam-medetomidine in cheetahs. Journal of the American Veterinary Medical Association, 1998, Oct-01, Volume: 213, Issue:7 Topics: Acid-Base Equilibrium; Acinonyx; Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Dissociative; Animals; Blood Pressure; Body Temperature; Female; Heart Rate; Hypnotics and Sedatives; Imidazoles; Male; Medetomidine; Oxygen; Respiration; Tiletamine; Zolazepam	1998
Anesthesia of polar bears (Ursus maritimus) with zolazepam-tiletamine, medetomidine-ketamine, and medetomidine-zolazepam-tiletamine. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 1999, Volume: 30, Issue:3 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Animals, Wild; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Body Temperature; Female; Handling, Psychological; Hypnotics and Sedatives; Imidazoles; Immobilization; Ketamine; Male; Medetomidine; Pulse; Respiration; Tiletamine; Ursidae; Zolazepam	1999
Short duration anaesthesia with medetomidine and ketamine in cynomolgus monkeys. Laboratory animals, 1999, Volume: 33, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Anesthetics, Dissociative; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Heart Rate; Imidazoles; Injections, Intramuscular; Ketamine; Macaca fascicularis; Male; Medetomidine; Random Allocation; Respiration	1999
Capture and immobilisation of aardvark (Orycteropus afer) using different drug combinations. Journal of the South African Veterinary Association, 2000, Volume: 71, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Combined; Animals; Female; Halothane; Imidazoles; Immobilization; Ketamine; Male; Medetomidine; Midazolam; Xenarthra; Xylazine	2000
Sufentanil and medetomidine anaesthesia in the rat and its reversal with atipamezole and butorphanol. Laboratory animals, 2000, Volume: 34, Issue:3 Topics: Anesthesia; Anesthetics, Intravenous; Animals; Animals, Outbred Strains; Behavior, Animal; Butorphanol; Drug Combinations; Female; Imidazoles; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Medetomidine; Narcotic Antagonists; Oximetry; Oxygen; Rats; Rats, Wistar; Sufentanil; Time Factors	2000
Cardiopulmonary and anesthetic effects of medetomidine-ketamine-butorphanol and antagonism with atipamezole in servals (Felis serval). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2000, Volume: 31, Issue:3 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics, Dissociative; Animals; Animals, Zoo; Blood Gas Analysis; Butorphanol; Carnivora; Drug Combinations; Female; Heart; Heart Rate; Hypnotics and Sedatives; Imidazoles; Injections, Intramuscular; Ketamine; Lung; Male; Medetomidine; Respiration	2000
Medetomidine-ketamine anesthesia in red-eared slider turtles (Trachemys scripta elegans). Contemporary topics in laboratory animal science, 2001, Volume: 40, Issue:3 Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Dissociative; Animals; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Injections, Intramuscular; Intubation, Intratracheal; Ketamine; Medetomidine; Muscle, Skeletal; Random Allocation; Turtles	2001
Evaluation of an anesthetic regimen for retroorbital blood collection from mice. Contemporary topics in laboratory animal science, 2000, Volume: 39, Issue:2 Topics: Adrenergic alpha-Antagonists; Analgesics; Anesthesia; Anesthetics, Local; Animal Welfare; Animals; Blood Specimen Collection; Drug Interactions; Drug Therapy, Combination; Female; Imidazoles; Ketamine; Male; Medetomidine; Mice; Mice, Inbred Strains; Orbit; Propoxycaine; Rats	2000
Effects of atipamezole, an alpha 2-adrenoceptor antagonist, on the anesthesia induced by barbiturates and medetomidine. Anesthesia and analgesia, 1992, Volume: 75, Issue:3 Topics: Adrenergic alpha-Antagonists; Anesthesia; Anesthetics; Animals; Barbiturates; Drug Interactions; Drug Synergism; Imidazoles; Male; Medetomidine; Methohexital; Nociceptors; Pain Measurement; Pentobarbital; Rats; Rats, Inbred Strains; Reflex; Time Factors	1992
The antinociceptive actions of dexmedetomidine on dorsal horn neuronal responses in the anaesthetized rat. European journal of pharmacology, 1992, Apr-29, Volume: 215, Issue:1 Topics: Action Potentials; Adrenergic alpha-Antagonists; Analgesics; Anesthesia; Animals; Clonidine; Dose-Response Relationship, Drug; Electrophysiology; Imidazoles; Male; Medetomidine; Naloxone; Neurons; Nociceptors; Rats; Rats, Inbred Strains; Spinal Cord	1992
Fentanyl and medetomidine anaesthesia in the rat and its reversal using atipamazole and either nalbuphine or butorphanol. Laboratory animals, 1992, Volume: 26, Issue:1 Topics: Anesthesia; Animals; Butorphanol; Drinking Behavior; Drug Combinations; Eating; Fentanyl; Foot; Imidazoles; Medetomidine; Nalbuphine; Narcotic Antagonists; Rats; Rats, Inbred Strains; Reflex; Respiration; Tail	1992
The effects of medetomidine, an alpha-2-adrenoceptor agonist, and cocaine on the tooth pulp-evoked jaw-opening reflex in cat. Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Cats; Cocaine; Dental Pulp; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Imidazoles; Jaw; Medetomidine; Pain; Reflex	1991
Antagonistic activities of atipamezole, 4-aminopyridine and yohimbine against medetomidine/ketamine-induced anaesthesia in cats. The Veterinary record, 1991, Jan-19, Volume: 128, Issue:3 Topics: 4-Aminopyridine; Anesthesia; Animals; Cats; Heart Rate; Imidazoles; Injections, Intramuscular; Ketamine; Medetomidine; Posture; Respiration; Yohimbine	1991