Page last updated: 2024-10-23

atenolol and Pulmonary Arterial Remodeling

atenolol has been researched along with Pulmonary Arterial Remodeling in 2 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Research Excerpts

ExcerptRelevanceReference
"We hypothesized that nebivolol, a β-blocker with nitric oxide-mediated activity, compared with atenolol, a β-blocker without such activity, would decrease oxidative stress and improve the effects of endothelial dysfunction and wall shear stress (WSS), thereby reducing atherosclerosis progression and vulnerability in patients with nonobstructive coronary artery disease."5.22Comprehensive Assessment of Coronary Plaque Progression With Advanced Intravascular Imaging, Physiological Measures, and Wall Shear Stress: A Pilot Double-Blinded Randomized Controlled Clinical Trial of Nebivolol Versus Atenolol in Nonobstructive Coronary ( Ahn, SG; Corban, MT; Dhawan, S; Eshtehardi, P; Giddens, DP; Gogas, BD; Hung, OY; Maynard, C; McDaniel, MC; Molony, D; Piccinelli, M; Quyyumi, AA; Rasoul-Arzrumly, E; Samady, H; Timmins, LH, 2016)
"To investigate the effect and mechanism of nebivolol on aortic remodeling in N-nitro-l-arginine methyl ester (l-NAME)-induced hypertension."3.85Nebivolol alleviates aortic remodeling through eNOS upregulation and inhibition of oxidative stress in l-NAME-induced hypertensive rats. ( Li, Z; Liu, Y; Pang, X; Wang, Y; Wei, Z; Yin, S; Zhang, F, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, Y1
Zhang, F1
Liu, Y1
Yin, S1
Pang, X1
Li, Z1
Wei, Z1
Hung, OY1
Molony, D1
Corban, MT1
Rasoul-Arzrumly, E1
Maynard, C1
Eshtehardi, P1
Dhawan, S1
Timmins, LH1
Piccinelli, M1
Ahn, SG1
Gogas, BD1
McDaniel, MC1
Quyyumi, AA1
Giddens, DP1
Samady, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Evaluation of The Effects of Nebivolol in Comparison to Atenolol on Wall Shear Stress and Rupture Prone Coronary Artery Plaques in Patients With Moderate Coronary Artery Disease[NCT01230892]Phase 429 participants (Actual)Interventional2010-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Reduction of Thin-cap Fibroatheromas (TCFA) as Defined by VH-IVUS

Presence of thin-cap fibroatheroma as defined by virtual histology-intravascular ultrasound (VH-IVUS) (NCT01230892)
Timeframe: 1 year

Interventionparticipants (Number)
Nebivolol4
Atenolol6

Trials

1 trial available for atenolol and Pulmonary Arterial Remodeling

ArticleYear
Comprehensive Assessment of Coronary Plaque Progression With Advanced Intravascular Imaging, Physiological Measures, and Wall Shear Stress: A Pilot Double-Blinded Randomized Controlled Clinical Trial of Nebivolol Versus Atenolol in Nonobstructive Coronary
    Journal of the American Heart Association, 2016, Jan-25, Volume: 5, Issue:1

    Topics: Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Antagonists; Adult; Atenolol; Biomarkers; Coron

2016

Other Studies

1 other study available for atenolol and Pulmonary Arterial Remodeling

ArticleYear
Nebivolol alleviates aortic remodeling through eNOS upregulation and inhibition of oxidative stress in l-NAME-induced hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:7

    Topics: Animals; Antihypertensive Agents; Aorta; Arginine; Atenolol; Blood Pressure; Enzyme Inhibitors; Hype

2017