Page last updated: 2024-10-23

atenolol and Pre-Eclampsia

atenolol has been researched along with Pre-Eclampsia in 18 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.

Research Excerpts

ExcerptRelevanceReference
"Treatment with atenolol reduced the incidence of preeclampsia from 5 of 28 (18%) to 1 of 28 (3."6.69Prevention of preeclampsia: a randomized trial of atenolol in hyperdynamic patients before onset of hypertension. ( Brateng, D; Brown, Z; Easterling, TR; Millard, SP; Schmucker, B, 1999)
"Early treatment of high cardiac output with atenolol decreases the risk for preeclampsia."5.35Hemodynamically-directed atenolol therapy is associated with a blunted rise in maternal sFLT-1 levels during pregnancy. ( Brateng, DA; Carr, DB; Easterling, TR; Karumanchi, SA; Kawamura, C; Shofer, JB; Tran, LT, 2009)
" The incidence of severe hypertension was significantly lower when nifedipine (odds ratio, 0."5.05Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020)
"Atenolol taken at the time of conception and/or during the first trimester of pregnancy was associated with low birth weight."3.71Anti-hypertensive drugs in pregnancy and fetal growth: evidence for "pharmacological programming" in the first trimester? ( Bayliss, H; Beevers, DG; Beevers, M; Churchill, D, 2002)
"Atenolol therapy was not randomized."2.70The relationship between hemodynamics and inflammatory activation in women at risk for preeclampsia. ( Brateng, D; Carr, DB; Desai, M; Easterling, TR; McDonald, GB; Thach, CT, 2001)
"Treatment with atenolol reduced the incidence of preeclampsia from 5 of 28 (18%) to 1 of 28 (3."2.69Prevention of preeclampsia: a randomized trial of atenolol in hyperdynamic patients before onset of hypertension. ( Brateng, D; Brown, Z; Easterling, TR; Millard, SP; Schmucker, B, 1999)
"Myocardial infarction is rare in pregnancy."2.39Myocardial infarction in a parturient. A case report with emphasis on medication and management. ( Haring, P; Hietakorpi, S; Koski, E; Nuutinen, LS; Purhonen, S; Söderlin, MK, 1994)
"Early treatment of high cardiac output with atenolol decreases the risk for preeclampsia."1.35Hemodynamically-directed atenolol therapy is associated with a blunted rise in maternal sFLT-1 levels during pregnancy. ( Brateng, DA; Carr, DB; Easterling, TR; Karumanchi, SA; Kawamura, C; Shofer, JB; Tran, LT, 2009)
"Hyperdynamic patients had less preeclampsia, less severe preeclampsia, fewer deliveries <34 weeks, and fewer neonatal intensive care unit days compared with those requiring a vasodilator."1.35Outcomes of pregnancies at risk for hypertensive complications managed using impedance cardiography. ( Chaffin, DG; Webb, DG, 2009)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's4 (22.22)18.2507
2000's9 (50.00)29.6817
2010's1 (5.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Bellos, I1
Pergialiotis, V1
Papapanagiotou, A1
Loutradis, D1
Daskalakis, G1
Duan, L1
Ng, A1
Chen, W1
Spencer, HT1
Nguyen, J1
Shen, AY1
Lee, MS1
Carr, DB2
Tran, LT1
Brateng, DA1
Kawamura, C1
Shofer, JB1
Karumanchi, SA1
Easterling, TR3
Chaffin, DG1
Webb, DG1
Bayliss, H2
Churchill, D2
Beevers, M1
Beevers, DG1
Damron, DP1
Arxer, A1
Pardina, B1
Blas, I1
Ramió, L1
Villalonga, A1
Fuerst, M1
Söderlin, MK1
Purhonen, S1
Haring, P1
Hietakorpi, S1
Koski, E1
Nuutinen, LS1
Ellis, MR1
Kane, KY1
Beevers, G1
Carbonne, B1
Jannet, D1
Milliez, J1
Brateng, D2
Schmucker, B1
Brown, Z1
Millard, SP1
McDonald, GB1
Desai, M1
Thach, CT1
Rollins, G1
Lunell, NO1
Persson, B1
Aragon, G1
Fredholm, BB1
Aström, H1
Blake, S1
MacDonald, D1
Hanretty, KP1
Whittle, MJ1
Rubin, PC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Maternal Hemodynamic Monitoring in Women Undergoing Cesarean Section by Use of NICaS Cardiac Impedance[NCT02902068]200 participants (Actual)Observational2016-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for atenolol and Pre-Eclampsia

ArticleYear
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:4

    Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease

2020
Myocardial infarction in a parturient. A case report with emphasis on medication and management.
    Anaesthesia, 1994, Volume: 49, Issue:10

    Topics: Adult; Aspirin; Atenolol; Delivery, Obstetric; Drug Therapy, Combination; Female; Humans; Myocardial

1994

Trials

5 trials available for atenolol and Pre-Eclampsia

ArticleYear
Chronic hypertension in pregnancy.
    Obstetrics and gynecology, 2002, Volume: 100, Issue:6

    Topics: Atenolol; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; F

2002
Beta-blockers may have role in preeclampsia.
    JAMA, 1982, Aug-06, Volume: 248, Issue:5

    Topics: Adrenergic beta-Antagonists; Atenolol; Birth Weight; Clinical Trials as Topic; Female; Humans; Hyper

1982
Prevention of preeclampsia: a randomized trial of atenolol in hyperdynamic patients before onset of hypertension.
    Obstetrics and gynecology, 1999, Volume: 93, Issue:5 Pt 1

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Birth Weight; Cardiac Output; Double-Blind Method; Fem

1999
The relationship between hemodynamics and inflammatory activation in women at risk for preeclampsia.
    Obstetrics and gynecology, 2001, Volume: 98, Issue:6

    Topics: Adult; Antigens, CD; Antihypertensive Agents; Atenolol; Cardiac Output, High; Female; Fibronectins;

2001
The prevention of the maternal manifestations of pre-eclampsia by intensive antihypertensive treatment.
    British journal of obstetrics and gynaecology, 1991, Volume: 98, Issue:3

    Topics: Adult; Atenolol; Bendroflumethiazide; Birth Weight; Drug Therapy, Combination; Embryonic and Fetal D

1991

Other Studies

11 other studies available for atenolol and Pre-Eclampsia

ArticleYear
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
    JAMA internal medicine, 2017, 06-01, Volume: 177, Issue:6

    Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; Californi

2017
Hemodynamically-directed atenolol therapy is associated with a blunted rise in maternal sFLT-1 levels during pregnancy.
    Hypertension in pregnancy, 2009, Volume: 28, Issue:1

    Topics: Adult; Antihypertensive Agents; Atenolol; Cardiac Output, High; Female; Hemodynamics; Humans; Longit

2009
Outcomes of pregnancies at risk for hypertensive complications managed using impedance cardiography.
    American journal of perinatology, 2009, Volume: 26, Issue:10

    Topics: Adult; Antihypertensive Agents; Atenolol; Cardiography, Impedance; Female; Hemodynamics; Humans; Inf

2009
Anti-hypertensive drugs in pregnancy and fetal growth: evidence for "pharmacological programming" in the first trimester?
    Hypertension in pregnancy, 2002, Volume: 21, Issue:2

    Topics: Antihypertensive Agents; Atenolol; Embryonic and Fetal Development; Female; Humans; Hypertension; In

2002
Dural sinus thrombosis in a late preeclamptic woman.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2004, Volume: 51, Issue:10

    Topics: Adult; Anticoagulants; Antihypertensive Agents; Atenolol; Cerebral Veins; Female; Heparin; Humans; M

2004
Atenolol for prevention of preeclampsia.
    The Journal of family practice, 1999, Volume: 48, Issue:8

    Topics: Antihypertensive Agents; Atenolol; Birth Weight; Cardiac Output; Double-Blind Method; Female; Humans

1999
Fetal growth restriction.
    Lancet (London, England), 2000, Apr-15, Volume: 355, Issue:9212

    Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Clinical Trials as Topic; Female; Fetal Growth Re

2000
Fetal growth restriction.
    Lancet (London, England), 2000, Apr-15, Volume: 355, Issue:9212

    Topics: Antihypertensive Agents; Atenolol; Bias; Blood Pressure; Clinical Trials as Topic; Female; Fetal Gro

2000
Guidelines on high blood pressure in pregnancy give new classifications of disease.
    Report on medical guidelines & outcomes research, 2000, Dec-18, Volume: 11, Issue:24

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Contra

2000
Circulatory and metabolic effects of acute beta 1-blockade in severe pre-eclampsia.
    Acta obstetricia et gynecologica Scandinavica, 1979, Volume: 58, Issue:5

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Glucose; Blood Pressure; Cyclic AMP;

1979
Reappearance of end-diastolic velocity in a pregnancy complicated by severe pregnancy-induced hypertension.
    American journal of obstetrics and gynecology, 1988, Volume: 158, Issue:5

    Topics: Adult; Atenolol; Blood Flow Velocity; Diastole; Female; Humans; Hypertension; Pre-Eclampsia; Pregnan

1988