Page last updated: 2024-10-23

atenolol and Metabolic Syndrome

atenolol has been researched along with Metabolic Syndrome in 11 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
"To comparatively estimate the time course of changes in key metabolic parameters and quality of life (QL) in patients with coronary heart disease during 4-week therapy with atenolol and amlodipine."9.17[Comparative evaluation of the impact of four-week therapy with amlodipine and atenolol on quality of life and blood lipid composition in patients with coronary heart disease associated with metabolic syndrome]. ( Bespalova, LD; Kalyuzhin, VV; Kalyuzhina, EV; Kolesnikov, RN; Pushnikova, EY; Teplyakov, AT, 2013)
"Combination therapy of nitrendipine and atenolol may significantly increase BW and fasting BG in overweight or obese patients with hypertension."9.14Effect of metformin on weight gain during antihypertensive treatment with a beta-blocker in Chinese patients. ( Qin, YW; Qiu, JL; Zhang, JL; Zhao, XX; Zheng, X; Zou, DJ, 2009)
"The objective of the present study was to explore the effect of carvedilol treatment on metabolic parameters in patients with metabolic syndrome."9.12The effect of carvedilol on metabolic parameters in patients with metabolic syndrome. ( Oguz, A; Uzunlulu, M; Yorulmaz, E, 2006)
"The present post-hoc analyses were aimed at: describing the prevalence of the metabolic syndrome (MS) at baseline; investigating the effect of long-term antihypertensive therapy (and separately of atenolol and lacidipine) on MS prevalence; exploring whether MS at baseline influenced changes in carotid IMT and incidence of cardiovascular events during treatment; and describing the relations between MS and new cases of diabetes developing during treatment."9.12Prevalence and incidence of the metabolic syndrome in the European Lacidipine Study on Atherosclerosis (ELSA) and its relation with carotid intima-media thickness. ( Baurecht, H; Carugo, S; Cuspidi, C; Hennig, M; Mancia, G; Tang, R; Zanchetti, A, 2007)
"Metabolic syndrome patients with hypertension (n=28) and a control group (n=20) were given atenolol (50 mg/day) for 4 weeks."7.77The enhanced effect of atenolol on hypertension in metabolic syndrome. ( Satou, Y; Ueno, N, 2011)
"To comparatively estimate the time course of changes in key metabolic parameters and quality of life (QL) in patients with coronary heart disease during 4-week therapy with atenolol and amlodipine."5.17[Comparative evaluation of the impact of four-week therapy with amlodipine and atenolol on quality of life and blood lipid composition in patients with coronary heart disease associated with metabolic syndrome]. ( Bespalova, LD; Kalyuzhin, VV; Kalyuzhina, EV; Kolesnikov, RN; Pushnikova, EY; Teplyakov, AT, 2013)
"Combination therapy of nitrendipine and atenolol may significantly increase BW and fasting BG in overweight or obese patients with hypertension."5.14Effect of metformin on weight gain during antihypertensive treatment with a beta-blocker in Chinese patients. ( Qin, YW; Qiu, JL; Zhang, JL; Zhao, XX; Zheng, X; Zou, DJ, 2009)
"The objective of the present study was to explore the effect of carvedilol treatment on metabolic parameters in patients with metabolic syndrome."5.12The effect of carvedilol on metabolic parameters in patients with metabolic syndrome. ( Oguz, A; Uzunlulu, M; Yorulmaz, E, 2006)
"The present post-hoc analyses were aimed at: describing the prevalence of the metabolic syndrome (MS) at baseline; investigating the effect of long-term antihypertensive therapy (and separately of atenolol and lacidipine) on MS prevalence; exploring whether MS at baseline influenced changes in carotid IMT and incidence of cardiovascular events during treatment; and describing the relations between MS and new cases of diabetes developing during treatment."5.12Prevalence and incidence of the metabolic syndrome in the European Lacidipine Study on Atherosclerosis (ELSA) and its relation with carotid intima-media thickness. ( Baurecht, H; Carugo, S; Cuspidi, C; Hennig, M; Mancia, G; Tang, R; Zanchetti, A, 2007)
"The aim of the Antihypertensive Treatment and Lipid Profile in a North of Sweden Efficacy Evaluation study was to compare the long-term effect of the commonly used inexpensive medication with a low-dose diuretic (hydrochlorothiazide), alone or in combination with a beta-adrenoceptor (atenolol), with that of more modern but also more expensive antihypertensive treatment with an angiotensin-II-receptor blocker (candesartan), alone or in combination with a calcium antagonist (felodipine), and to do so in newly diagnosed patients with primary hypertension."5.10Metabolic outcome during 1 year in newly detected hypertensives: results of the Antihypertensive Treatment and Lipid Profile in a North of Sweden Efficacy Evaluation (ALPINE study). ( Alaupovic, P; Carlberg, B; Lindholm, LH; Persson, M; Samuelsson, O; Svensson, A, 2003)
"Metabolic syndrome patients with hypertension (n=28) and a control group (n=20) were given atenolol (50 mg/day) for 4 weeks."3.77The enhanced effect of atenolol on hypertension in metabolic syndrome. ( Satou, Y; Ueno, N, 2011)
"Atenolol, a first-generation β-blocker, effectively reduces blood pressure, although its use in metabolic syndrome remains controversial."3.77Long-term treatment with nebivolol attenuates renal damage in Zucker diabetic fatty rats. ( Angerosa, M; Cao, G; Dominici, FP; Giani, JF; Muñoz, MC; Toblli, JE, 2011)
"We evaluated the effects of nebivolol, a third-generation highly selective [beta]-blocker with additional vasodilating activity, versus the traditional [beta]-blocker atenolol in controlling functional and morphological cardiovascular damage in a rat model of metabolic syndrome."3.76Cardiovascular protective effects of nebivolol in Zucker diabetic fatty rats. ( Angerosa, M; Cao, G; Dominici, F; Giani, J; Munoz, M; Rivas, C; Toblli, J, 2010)
"Seventy five patients with metabolic syndrome aged 40-59 years were included into an open study with parallel groups in which the following combinations of lipid lowering and antihypertensive drugs were used for sweeksinch: atorvastatin + perindopril (n=17, group 1); simvastatin + atenolol (n=17, group 2); fenofibrate + atenolol (n=21, group 3), and simvastatin + indapamide (n=20, group 4)."3.72[Effect of combined antihypertensive and lipid lowering therapy on the level of coronary risk and tissue insulin resistance in patients with metabolic syndrome]. ( Khadipash, LA; Kiseleva, NV; Kosmatova, OV; Mamedov, MN; Oganov, RG; Perova, NV, 2003)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (63.64)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kalyuzhin, VV1
Teplyakov, AT1
Pushnikova, EY1
Bespalova, LD1
Kalyuzhina, EV1
Kolesnikov, RN1
Zhang, JL1
Zheng, X1
Zou, DJ1
Qiu, JL1
Zhao, XX1
Qin, YW1
Toblli, J1
Cao, G2
Rivas, C1
Munoz, M1
Giani, J1
Dominici, F1
Angerosa, M2
Ueno, N1
Satou, Y1
Toblli, JE1
Giani, JF1
Muñoz, MC1
Dominici, FP1
Lindholm, LH1
Persson, M1
Alaupovic, P1
Carlberg, B1
Svensson, A1
Samuelsson, O1
Mamedov, MN1
Perova, NV1
Kosmatova, OV1
Khadipash, LA1
Kiseleva, NV1
Oganov, RG1
Baumgart, P1
Uzunlulu, M1
Oguz, A1
Yorulmaz, E1
Safar, ME1
Zanchetti, A1
Hennig, M1
Baurecht, H1
Tang, R1
Cuspidi, C1
Carugo, S1
Mancia, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Antihypertensive Treatment on Cardiac Remodelling and Metabolic Profile in HIV Infected Patients: Randomized Longitudinal Study With Candesartan Versus Lercanidipine[NCT00564057]Phase 430 participants (Anticipated)Interventional2007-09-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for atenolol and Metabolic Syndrome

ArticleYear
[Comparative evaluation of the impact of four-week therapy with amlodipine and atenolol on quality of life and blood lipid composition in patients with coronary heart disease associated with metabolic syndrome].
    Terapevticheskii arkhiv, 2013, Volume: 85, Issue:5

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Amlodipine; Angina, Stable; Atenolol; Calcium Channel

2013
Effect of metformin on weight gain during antihypertensive treatment with a beta-blocker in Chinese patients.
    American journal of hypertension, 2009, Volume: 22, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Body Mass Index

2009
Metabolic outcome during 1 year in newly detected hypertensives: results of the Antihypertensive Treatment and Lipid Profile in a North of Sweden Efficacy Evaluation (ALPINE study).
    Journal of hypertension, 2003, Volume: 21, Issue:8

    Topics: Antihypertensive Agents; Apolipoproteins; Atenolol; Blood Glucose; Blood Pressure; Drug Therapy, Com

2003
The effect of carvedilol on metabolic parameters in patients with metabolic syndrome.
    International heart journal, 2006, Volume: 47, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anthropometry; Antihypertensive Ag

2006
Prevalence and incidence of the metabolic syndrome in the European Lacidipine Study on Atherosclerosis (ELSA) and its relation with carotid intima-media thickness.
    Journal of hypertension, 2007, Volume: 25, Issue:12

    Topics: Aged; Antihypertensive Agents; Atenolol; Atherosclerosis; Calcium Channel Blockers; Carotid Arteries

2007

Other Studies

6 other studies available for atenolol and Metabolic Syndrome

ArticleYear
Cardiovascular protective effects of nebivolol in Zucker diabetic fatty rats.
    Journal of hypertension, 2010, Volume: 28, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Aorta; Atenolol; Benzopyrans; Blood Pressure; Cardiovascular D

2010
The enhanced effect of atenolol on hypertension in metabolic syndrome.
    Metabolic syndrome and related disorders, 2011, Volume: 9, Issue:5

    Topics: Adrenergic beta-Antagonists; Atenolol; Blood Glucose; Blood Pressure; Body Mass Index; Case-Control

2011
Long-term treatment with nebivolol attenuates renal damage in Zucker diabetic fatty rats.
    Journal of hypertension, 2011, Volume: 29, Issue:8

    Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Atenolol; Benzopyrans; Blood Pressure; Diabetes Mel

2011
[Effect of combined antihypertensive and lipid lowering therapy on the level of coronary risk and tissue insulin resistance in patients with metabolic syndrome].
    Kardiologiia, 2003, Volume: 43, Issue:3

    Topics: Adult; Antihypertensive Agents; Atenolol; Atorvastatin; Blood Pressure; Cholesterol, HDL; Cholestero

2003
[Antihypertensive therapy: risk stratification in diabetes and cardiac diseases].
    MMW Fortschritte der Medizin, 2006, Mar-16, Volume: 148, Issue:11

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2006
Pulse pressure: a help in medical semiology for metabolic syndrome.
    American journal of hypertension, 2007, Volume: 20, Issue:2

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Blood Pressure; Blo

2007