Page last updated: 2024-10-23

atenolol and Long QT Syndrome

atenolol has been researched along with Long QT Syndrome in 20 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"To evaluate effects of carvedilol (Akridilol, AKRIKHIN, Russia) on central hemodynamics, microvascular bed, hemorheology, von Willebrand factor (VWF) activity, clinical efficacy of the drug and influence on exercise tolerance in patients with Q myocardial infarction (QMI) compared to therapy with atenolol."9.11[Carvedilol in combined therapy of patients with Q myocardial infarction]. ( Iakovleva, MS; Mironova, MA; Sadionchenko, VS; Shekhian, GG, 2005)
"In order to dissociate the Class III effects of sotalol on QT interval and arrhythmias from those of chronic beta-receptor blockade, we compared the effects of sotalol 160 mg b."9.06A comparison of the long-term effects of sotalol and atenolol on QT interval and arrhythmias after myocardial infarction. ( Alexopoulos, D; Cobbe, PC; Cobbe, SM; Johnston, J; McCaie, CP; Winner, SJ, 1988)
"Twenty children and adolescents treated orally with atenolol for chronic paroxysmal ventricular tachycardia (n = 10) or Long QT Syndrome (n = 10) over a 5 year period were retrospectively evaluated to ascertain the efficacy of arrhythmia suppression, the effective dosage, the cardiovascular effects, and the incidence of adverse effects."7.68Atenolol in children with ventricular arrhythmias. ( Gillette, PC; Trippel, DL, 1990)
"To evaluate effects of carvedilol (Akridilol, AKRIKHIN, Russia) on central hemodynamics, microvascular bed, hemorheology, von Willebrand factor (VWF) activity, clinical efficacy of the drug and influence on exercise tolerance in patients with Q myocardial infarction (QMI) compared to therapy with atenolol."5.11[Carvedilol in combined therapy of patients with Q myocardial infarction]. ( Iakovleva, MS; Mironova, MA; Sadionchenko, VS; Shekhian, GG, 2005)
"In order to dissociate the Class III effects of sotalol on QT interval and arrhythmias from those of chronic beta-receptor blockade, we compared the effects of sotalol 160 mg b."5.06A comparison of the long-term effects of sotalol and atenolol on QT interval and arrhythmias after myocardial infarction. ( Alexopoulos, D; Cobbe, PC; Cobbe, SM; Johnston, J; McCaie, CP; Winner, SJ, 1988)
"Twenty children and adolescents treated orally with atenolol for chronic paroxysmal ventricular tachycardia (n = 10) or Long QT Syndrome (n = 10) over a 5 year period were retrospectively evaluated to ascertain the efficacy of arrhythmia suppression, the effective dosage, the cardiovascular effects, and the incidence of adverse effects."3.68Atenolol in children with ventricular arrhythmias. ( Gillette, PC; Trippel, DL, 1990)
"Levobupivacaine was substituted for routine racemic bupivacaine to decrease the risk of drug-induced cardiotoxicity."1.33Long QT syndrome: anaesthetic management at delivery. ( Behl, S; Wauchob, TD, 2005)
"Long QT syndrome is characterized by familial syncope and sudden death in the context of sudden heart rate changes."1.31Beta blockers normalize QT hysteresis in long QT syndrome. ( Chauhan, V; Hegele, RA; Klein, GJ; Krahn, AD; Skanes, AC; Wang, J; Yee, R, 2002)
"However, the incidence of sudden death and aborted sudden death (24% in all patients and 17% in compliant patients) strongly suggests the use of a "back-up" defibrillator, particularly in noncompliant adolescent patients."1.30Long-term follow-up of patients with long-QT syndrome treated with beta-blockers and continuous pacing. ( Belhassen, B; Dorostkar, PC; Eldar, M; Scheinman, MM, 1999)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's5 (25.00)18.2507
2000's7 (35.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abu-Zeitone, A1
Peterson, DR1
Polonsky, B1
McNitt, S1
Moss, AJ2
Wong, JA1
Gula, LJ1
Klein, GJ2
Yee, R2
Skanes, AC2
Krahn, AD2
Moltedo, JM1
Kim, JJ1
Friedman, RA1
Kertesz, NJ1
Cannon, BC1
Mikesell, CE1
Atkinson, DE1
Rachman, BR1
Farhoumand, AD1
Trombert, V1
Eusebio, J1
Hwang, SW1
Thomas, JG1
Whitehead, WE1
Curry, DJ1
Dauser, RC1
Kim, ES1
Luerssen, TG1
Jea, A1
Behl, S1
Wauchob, TD1
Sadionchenko, VS1
Iakovleva, MS1
Shekhian, GG1
Mironova, MA1
Murphy, I1
Moneley, D1
Kelly, D1
Foley, B1
Sheehan, S1
Perry, GY1
Kosar, EM1
Majewski, J1
Lelakowski, J1
Dorostkar, PC1
Eldar, M1
Belhassen, B1
Scheinman, MM1
Zareba, W1
Hall, WJ1
Schwartz, PJ1
Crampton, RS1
Benhorin, J1
Vincent, GM1
Locati, EH1
Priori, SG1
Napolitano, C1
Medina, A1
Zhang, L1
Robinson, JL1
Timothy, K1
Towbin, JA1
Andrews, ML1
Furushima, H1
Chinushi, M1
Washizuka, T1
Aizawa, Y1
RaviƱa, T1
Lapuerta, JA1
Brugada, J1
Chauhan, V1
Wang, J1
Hegele, RA1
Chien, WW1
Foster, E1
Phillips, B1
Schiller, N1
Griffin, JC1
Trippel, DL1
Gillette, PC1
Cobbe, SM1
Alexopoulos, D1
Winner, SJ1
McCaie, CP1
Cobbe, PC1
Johnston, J1
Rynkiewicz, A1
Rossi, P1
Yusuf, S1
Sleight, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Long QT Syndrome-Population Genetics and Cardiac Studies[NCT00005176]2,125 participants (Actual)Observational1985-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for atenolol and Long QT Syndrome

ArticleYear
Prolonged QT syndrome and sedation: a case report and a review of the literature.
    Pediatric emergency care, 2011, Volume: 27, Issue:2

    Topics: Arrhythmias, Cardiac; Atenolol; Child, Preschool; Conscious Sedation; Electrocardiography; Emergency

2011

Trials

6 trials available for atenolol and Long QT Syndrome

ArticleYear
Utility of treadmill testing in identification and genotype prediction in long-QT syndrome.
    Circulation. Arrhythmia and electrophysiology, 2010, Volume: 3, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Electrocardiography; ERG1 Potassium Channe

2010
[Carvedilol in combined therapy of patients with Q myocardial infarction].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Atenolol; Carbazoles; Carvedilol; Drug

2005
Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome.
    Circulation, 2000, Feb-15, Volume: 101, Issue:6

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Child; Child, Preschool; Female; Humans; I

2000
Role of alpha1-blockade in congenital long QT syndrome: investigation by exercise stress test.
    Japanese circulation journal, 2001, Volume: 65, Issue:7

    Topics: Adolescent; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-A

2001
A comparison of the long-term effects of sotalol and atenolol on QT interval and arrhythmias after myocardial infarction.
    European heart journal, 1988, Volume: 9, Issue:1

    Topics: Adult; Aged; Arrhythmias, Cardiac; Atenolol; Cardiac Complexes, Premature; Clinical Trials as Topic;

1988
[Effect of atenolol on the QT interval in the acute phase of myocardial infarction].
    Kardiologia polska, 1988, Volume: 31, Issue:8

    Topics: Adult; Aged; Arrhythmias, Cardiac; Atenolol; Clinical Trials as Topic; Female; Humans; Long QT Syndr

1988

Other Studies

13 other studies available for atenolol and Long QT Syndrome

ArticleYear
Efficacy of different beta-blockers in the treatment of long QT syndrome.
    Journal of the American College of Cardiology, 2014, Sep-30, Volume: 64, Issue:13

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Child; Child, Preschool; Death, Sudden, Ca

2014
Use of a cardioselective beta-blocker for pediatric patients with prolonged QT syndrome.
    Pediatric cardiology, 2011, Volume: 32, Issue:1

    Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Atenolol; Child; Child, Preschool; Female; Heart

2011
[Practical ECG problems in the elderly patient. Case number 16. Moxifloxacin-associated QT interval prolongation].
    Revue medicale suisse, 2011, Mar-16, Volume: 7, Issue:286

    Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Anti-Infective Agents; Atenolol; Aza Compounds; Bradycard

2011
Left thorascopic sympathectomy for refractory long QT syndrome in children.
    Journal of neurosurgery. Pediatrics, 2011, Volume: 8, Issue:5

    Topics: Adolescent; Adrenergic beta-Antagonists; Atenolol; Cardiac Surgical Procedures; Child; Child, Presch

2011
Long QT syndrome: anaesthetic management at delivery.
    International journal of obstetric anesthesia, 2005, Volume: 14, Issue:4

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthetics, Local; Anti-Arr

2005
Endoscopic thoracic sympathectomy for long QT syndrome.
    Irish journal of medical science, 2008, Volume: 177, Issue:2

    Topics: Adrenergic beta-Antagonists; Atenolol; Defibrillators, Implantable; Electric Countershock; Female; H

2008
Problems in managing patients with long QT syndrome and implantable cardioverter defibrillators: a report of two cases.
    Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Defibrillators, Implantable; Electrocardiography; Fema

1996
[Hereditary long QT syndrome: our own experience].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1999, Volume: 52, Issue:1-2

    Topics: Adolescent; Adrenergic beta-Antagonists; Atenolol; Electrocardiography; Female; Humans; Long QT Synd

1999
Long-term follow-up of patients with long-QT syndrome treated with beta-blockers and continuous pacing.
    Circulation, 1999, Dec-14, Volume: 100, Issue:24

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Child; Child, Preschool; Cohort Stud

1999
Prolonged repolarization in long QT3 syndrome: unusual electrocardiographic findings.
    International journal of cardiology, 2002, Volume: 82, Issue:1

    Topics: Anti-Arrhythmia Agents; Atenolol; Child; Defibrillators, Implantable; Electrocardiography; Humans; L

2002
Beta blockers normalize QT hysteresis in long QT syndrome.
    American heart journal, 2002, Volume: 143, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Analysis of Variance; Anti-Arrhythmia Agents; Atenol

2002
Pacemaker syndrome in a patient with DDD pacemaker for long QT syndrome.
    Pacing and clinical electrophysiology : PACE, 1991, Volume: 14, Issue:8

    Topics: Atenolol; Echocardiography; Electrocardiography; Heart Rate; Humans; Long QT Syndrome; Male; Middle

1991
Atenolol in children with ventricular arrhythmias.
    American heart journal, 1990, Volume: 119, Issue:6

    Topics: Adolescent; Arrhythmias, Cardiac; Atenolol; Cardiovascular System; Dose-Response Relationship, Drug;

1990