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atenolol and Liver Diseases

atenolol has been researched along with Liver Diseases in 3 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Liver Diseases: Pathological processes of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Atenolol is a hydrophilic betareceptor blocking drug, which is predominantly eliminated via the kidneys, only about 5% of the atenolol is metabolised by the liver."2.36Clinical pharmacokinetics of atenolol--a review. ( Görg, KG; Kirch, W, 1982)
" Hepatic pharmacokinetic modelling was performed with a two-phase physiologically-based organ pharmacokinetic model with the vascular space and dispersion evaluated with the MID technique."1.38Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage. ( Crawford, DH; Fletcher, LM; Li, P; Roberts, MS; Robertson, TA; Weiss, M; Zhang, Q, 2012)
" Thus, plasma half-life after intravenous dosing of atenolol was 6."1.27Clinical experience with atenolol in patients with chronic liver disease. ( Braun, W; Kirch, W; Mutschler, E; Ohnhaus, EE; Schäfer-Korting, M, 1983)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, P1
Robertson, TA1
Zhang, Q1
Fletcher, LM1
Crawford, DH1
Weiss, M1
Roberts, MS1
Kirch, W2
Görg, KG1
Schäfer-Korting, M1
Mutschler, E1
Ohnhaus, EE1
Braun, W1

Reviews

1 review available for atenolol and Liver Diseases

ArticleYear
Clinical pharmacokinetics of atenolol--a review.
    European journal of drug metabolism and pharmacokinetics, 1982, Volume: 7, Issue:2

    Topics: Administration, Oral; Atenolol; Biological Availability; Drug Interactions; Humans; Injections, Intr

1982

Other Studies

2 other studies available for atenolol and Liver Diseases

ArticleYear
Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage.
    Pharmaceutical research, 2012, Volume: 29, Issue:6

    Topics: Adrenergic Antagonists; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti

2012
Clinical experience with atenolol in patients with chronic liver disease.
    Journal of clinical pharmacology, 1983, Volume: 23, Issue:4

    Topics: Administration, Oral; Adult; Atenolol; Chronic Disease; Female; Humans; Injections, Intravenous; Kid

1983