Page last updated: 2024-10-23

atenolol and Hypotension

atenolol has been researched along with Hypotension in 40 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Antianginal efficacy of atenolol (A) and isosorbide dinitrate (ID) was compared in a long-term randomized, single-blind, crossover, placebo controlled trial in 71 patients with combined stable angina pectoris and chronic hypotension (Hpts) and in 38 normotensive patients with angina of effort (Npts)."9.09[The comparison of the efficacy of atenolol and isosorbide dinitrate therapy in chronic hypotension patients with stable angina pectoris]. ( Borovkova, NV; Chernov, VI; Idrisova, EM; Karpov, RS; Stepacheva, TA, 2001)
"A 30 year-old male patient with accelerated arterial hypertension relatively resistent to diazoxide received a single oral dose of 100 mg of atenolol, following which hypotension of more than 24 hours duration and acute renal failure ensued."7.66[Prolonged hypotension after the first dose of atenolol (author's transl)]. ( Botey, A; Darnell, A; Montoliu, J; Revert, L, 1981)
"Antianginal efficacy of atenolol (A) and isosorbide dinitrate (ID) was compared in a long-term randomized, single-blind, crossover, placebo controlled trial in 71 patients with combined stable angina pectoris and chronic hypotension (Hpts) and in 38 normotensive patients with angina of effort (Npts)."5.09[The comparison of the efficacy of atenolol and isosorbide dinitrate therapy in chronic hypotension patients with stable angina pectoris]. ( Borovkova, NV; Chernov, VI; Idrisova, EM; Karpov, RS; Stepacheva, TA, 2001)
"A short cut review was carried out to establish whether a glucagon infusion is of benefit in patients with refractory anaphylaxis."4.82Best evidence topic report. Glucagon infusion in refractory anaphylactic shock in patients on beta-blockers. ( Crawford, I; Thomas, M, 2005)
"A case of massive atenolol ingestion leading to hypotension in association with PR and QRS interval prolongation on the electrocardiogram is presented."4.81Cardiovascular depression resulting from atenolol intoxication. ( Elshami, J; Love, JN, 2002)
"The present study aimed to analyze and compare the interaction of passive cigarette smoking and hypertension on epinephrine and felypressin blood pressure effects after intravascular injection."3.96Passive Cigarette Smoking Impact on Blood Pressure Response to Epinephrine and Felypressin in 1K1C Hypertensive Rats Treated or not with Atenolol. ( Almeida, EPM; Amaral, SL; Calvo, AM; Dionisio, TJ; Faria, FAC; Fleury, CA; Oliveira, GM; Santos, CF, 2020)
"Changes in FHR and autonomic tones were studied (i) after electrical vagal stimulation and (ii) during nitroprusside-induced hypotension, in seven late gestation ovine fetus in control condition (ctrl), after dobutamine (beta1-activation) and atenolol (beta1-blockade)."3.73Influence of sympathetic tone on heart rate during vagal stimulation and nitroprusside induced hypotension in ovine fetus. ( Beuchée, A; Carré, F; Gaillot, T; Jaillard, S; Nuyt, AM; Pladys, P; Storme, L, 2005)
"Hypotension occurred following a combined beta blocker (atenolol), angiotensin converting enzyme inhibitor (quinapil) and selective serotonin reuptake inhibitor (fluvoxamine) overdose."3.71Aminophylline reversal of antihypertensive agent toxicity. ( Roberge, RJ; Rosetti, JM; Rossetti, ML, 2001)
"This study demonstrates that the tachycardia produced by systemic injections of the beta-adrenoceptor agonist, isoproterenol (10 microg/kg, i."3.70In vivo evidence that isoproterenol may increase heart rate in the rat by mechanisms in addition to activation of cardiac beta(1)- or beta(2)-adrenoceptors. ( Lewis, SJ; Whalen, EJ, 1999)
"Intravenous atenolol was given to 31 patients just before balloon mitral valvotomy to assess the hemodynamic efficacy and safety of beta-blockade in mitral stenosis complicated by pulmonary hypertension."3.68Pulmonary hypertension is a contraindication to beta-blockade in patients with severe mitral stenosis. ( Essop, R; Middlemost, S; Rothlisberger, C; Sareli, P; Skoularigis, J; Skudicky, D; Wisenbaugh, T, 1993)
"A 30 year-old male patient with accelerated arterial hypertension relatively resistent to diazoxide received a single oral dose of 100 mg of atenolol, following which hypotension of more than 24 hours duration and acute renal failure ensued."3.66[Prolonged hypotension after the first dose of atenolol (author's transl)]. ( Botey, A; Darnell, A; Montoliu, J; Revert, L, 1981)
"Midlife hypertension is an important risk factor for cognitive impairment and dementia, including Alzheimer's disease."1.91Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats. ( Bakker, ENTP; Coolen, BF; de Vos, J; Heijst, JA; Jongenelen, CAM; Naessens, DMP; Richard, E; Scholl, ER; Strijkers, GJ; Teunissen, CE; van der Wel, NN; VanBavel, E; Wilhelmus, MMM, 2023)
"Neurally mediated hypotension is now recognised as a common cause of otherwise unexplained recurrent syncope, but has not been reported in association with chronic fatigue."1.29Is neurally mediated hypotension an unrecognised cause of chronic fatigue? ( Bou-Holaigah, I; Calkins, H; Kan, JS; Rowe, PC, 1995)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199013 (32.50)18.7374
1990's9 (22.50)18.2507
2000's11 (27.50)29.6817
2010's5 (12.50)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Naessens, DMP1
de Vos, J1
Richard, E1
Wilhelmus, MMM1
Jongenelen, CAM1
Scholl, ER1
van der Wel, NN1
Heijst, JA1
Teunissen, CE1
Strijkers, GJ1
Coolen, BF1
VanBavel, E1
Bakker, ENTP1
Fleury, CA2
Almeida, EPM1
Dionisio, TJ2
Calvo, AM1
Oliveira, GM1
Amaral, SL2
Santos, CF2
Faria, FAC1
Shinomiya, S1
Shibamoto, T1
Kurata, Y1
Kuda, Y1
Zhang, W1
Tanida, M1
Toga, H1
Hoot, NR1
Benitez, JG1
Palm, KH1
Andreo, VC1
Lomba, PC1
Faria, FA1
Schneider, GS1
Cave, G1
Harvey, M1
Wang, Q1
Maillard, M1
Schibler, U1
Burnier, M1
Gachon, F1
Love, JN1
Elshami, J1
Lahlou, S1
Höcht, C1
Opezzo, JA1
Taira, CA1
Thomas, M1
Crawford, I1
Jacob, F1
LaBine, BG1
Ariza, P1
Katz, SA1
Osborn, JW1
Gaillot, T1
Beuchée, A1
Jaillard, S1
Storme, L1
Nuyt, AM1
Carré, F1
Pladys, P1
Wolfson, R1
Su, DH1
Ang, PS1
Tow, SL1
Sleight, P1
Paakkari, P1
Paakkari, I1
Karppanen, H1
Paasonen, MK1
Woods, DL1
Morrell, DF1
Montoliu, J1
Botey, A1
Darnell, A1
Revert, L1
Opie, LH1
White, DA1
Walden, RJ1
Rowe, PC1
Bou-Holaigah, I1
Kan, JS1
Calkins, H1
Tripathi, M1
Singh, PK1
Wisenbaugh, T1
Essop, R1
Middlemost, S1
Skoularigis, J1
Rothlisberger, C1
Skudicky, D1
Sareli, P1
Dunbar, JC1
O'Leary, DS1
Wang, G1
Wright-Richey, J1
Massin, MM1
Leroy, P1
Owens, P1
O'Brien, E1
Whalen, EJ1
Lewis, SJ1
Idrisova, EM1
Borovkova, NV1
Stepacheva, TA1
Chernov, VI1
Karpov, RS1
Roberge, RJ1
Rossetti, ML1
Rosetti, JM1
Bhatia, RS1
Nigam, P1
Kholeif, M1
Isles, C1
Webster, J1
Hubbard, JW1
Buchholz, RA1
Reed, K1
Nathan, MA1
Keeton, TK1
Eldor, J1
Hoffman, B1
Davidson, JT1
Giang, DW1
Isaeff, DM1
Freestone, S1
Thomas, HM1
Bhamra, RK1
Dyson, EH1
Abbasi, IA1
Sorsby, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"PGDT With the Hypotension Prediction Index to Reduce the Number and Duration of Intraoperative Hypotension and the Incidence of Renal Failure in Patients Undergoing Lung Surgery"[NCT04149314]142 participants (Actual)Interventional2019-11-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for atenolol and Hypotension

ArticleYear
Cardiovascular depression resulting from atenolol intoxication.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2002, Volume: 9, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Drug Overdose; Electrocardiography;

2002
Best evidence topic report. Glucagon infusion in refractory anaphylactic shock in patients on beta-blockers.
    Emergency medicine journal : EMJ, 2005, Volume: 22, Issue:4

    Topics: Adrenergic beta-Antagonists; Anaphylaxis; Angina Pectoris; Atenolol; Emergency Treatment; Glucagon;

2005

Trials

3 trials available for atenolol and Hypotension

ArticleYear
Beta-blockade in acute myocardial infarction.
    Advances in cardiology, 1982, Volume: 31

    Topics: Adrenergic beta-Antagonists; Atenolol; Bradycardia; Clinical Trials as Topic; Creatine Kinase; Elect

1982
[The comparison of the efficacy of atenolol and isosorbide dinitrate therapy in chronic hypotension patients with stable angina pectoris].
    Klinicheskaia meditsina, 2001, Volume: 79, Issue:1

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Dose-Response Relationship, Drug; Drug Resis

2001
Angiotensin converting enzyme inhibitors in the clinic: first-dose hypotension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1987, Volume: 5, Issue:3

    Topics: Atenolol; Bendroflumethiazide; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Hypotensi

1987

Other Studies

35 other studies available for atenolol and Hypotension

ArticleYear
Effect of long-term antihypertensive treatment on cerebrovascular structure and function in hypertensive rats.
    Scientific reports, 2023, 03-01, Volume: 13, Issue:1

    Topics: Amlodipine; Animals; Antihypertensive Agents; Atenolol; Carotid Artery, Common; Hypertension; Hypote

2023
Passive Cigarette Smoking Impact on Blood Pressure Response to Epinephrine and Felypressin in 1K1C Hypertensive Rats Treated or not with Atenolol.
    Arquivos brasileiros de cardiologia, 2020, Volume: 114, Issue:2

    Topics: Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Dose-Response Relationship, Drug; Drug I

2020
Nitric oxide and β(2)-adrenoceptor activation attenuate pulmonary vasoconstriction during anaphylactic hypotension in anesthetized BALB/c mice.
    Experimental lung research, 2013, Volume: 39, Issue:3

    Topics: Adrenergic beta-Antagonists; Anaphylaxis; Animals; Atenolol; Bronchoconstriction; Cyclooxygenase Inh

2013
Hemodynamically unstable: accidental atenolol toxicity?
    The Journal of emergency medicine, 2013, Volume: 45, Issue:3

    Topics: Abdominal Pain; Adult; Antihypertensive Agents; Atenolol; Bradycardia; Female; Gastrointestinal Agen

2013
Comparison of epinephrine and felypressin pressure effects in 1K1C hypertensive rats treated or not with atenolol.
    Journal of anesthesia, 2015, Volume: 29, Issue:1

    Topics: Animals; Atenolol; Blood Pressure; Epinephrine; Felypressin; Heart Rate; Hypertension; Hypotension;

2015
Anterior spinal cord syndrome after initiation of treatment with atenolol.
    The Journal of emergency medicine, 2010, Volume: 38, Issue:5

    Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Hypertension; Hypotension; Infarction; Intervertebral

2010
Lipid emulsion may augment early blood pressure recovery in a rabbit model of atenolol toxicity.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antidotes; Atenolol; Blood Pressure; Disease Models, Animal; F

2009
Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:4

    Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Atenolol; Basic-Leucine Zipper Transcription Fact

2010
Mechanisms underlying the cardiovascular responses to spinal dopamine receptor stimulation by apomorphine in anesthetized rats.
    Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3

    Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Apomorphine; Atenolol;

2003
Anterior hypothalamic beta-adrenergic activity in the maintenance of hypertension in aortic coarctated rats.
    Pharmacological research, 2004, Volume: 49, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anterior Hypothalamic Nucleus; Aorti

2004
Renal denervation causes chronic hypotension in rats: role of beta1-adrenoceptor activity.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Autonomic De

2005
Influence of sympathetic tone on heart rate during vagal stimulation and nitroprusside induced hypotension in ovine fetus.
    Autonomic neuroscience : basic & clinical, 2005, Dec-30, Volume: 123, Issue:1-2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Atenolol; B

2005
Unclassified cardiomyopathy in a geriatric cat.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2005, Volume: 46, Issue:9

    Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atenolol; Bradycardi

2005
Bilateral posterior ischemic optic neuropathy associated with use of sildenafil.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2008, Volume: 28, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Cytochrome P-450 Enzyme Inhibi

2008
Mechanisms of the inhibitory cardiovascular effects of taurine and homotaurine.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 677

    Topics: Animals; Atenolol; Atropine; Blood Pressure; Bradycardia; Depression, Chemical; Heart Rate; Hypotens

1983
Emergency treatment of high blood pressure with oral atenolol.
    British medical journal (Clinical research ed.), 1981, Jul-04, Volume: 283, Issue:6283

    Topics: Atenolol; Cerebral Infarction; Humans; Hypertension; Hypotension; Male; Middle Aged; Propanolamines

1981
Atenolol: side effects in a newborn infant.
    British medical journal (Clinical research ed.), 1982, Sep-11, Volume: 285, Issue:6343

    Topics: Atenolol; Bradycardia; Female; Humans; Hypertension; Hypotension; Infant, Newborn; Male; Maternal-Fe

1982
[Prolonged hypotension after the first dose of atenolol (author's transl)].
    Medicina clinica, 1981, Apr-25, Volume: 76, Issue:8

    Topics: Acute Kidney Injury; Adult; Atenolol; Diazoxide; Drug Synergism; Humans; Hypertension; Hypotension;

1981
Adverse interaction between nifedipine and beta-blockade.
    British medical journal, 1980, Nov-29, Volume: 281, Issue:6253

    Topics: Angina Pectoris; Atenolol; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Hypot

1980
Is neurally mediated hypotension an unrecognised cause of chronic fatigue?
    Lancet (London, England), 1995, Apr-29, Volume: 345, Issue:8957

    Topics: Atenolol; Disopyramide; Fatigue Syndrome, Chronic; Humans; Hypotension; Tilt-Table Test

1995
Is neurally mediated hypotension an unrecognised cause of chronic fatigue?
    Lancet (London, England), 1995, Mar-11, Volume: 345, Issue:8950

    Topics: Adolescent; Atenolol; Autonomic Nervous System Diseases; Blood Pressure; Child; Disopyramide; Fatigu

1995
Complete heart block after epidural anaesthesia in a patient on beta-blocker.
    Journal of the Indian Medical Association, 1994, Volume: 92, Issue:2

    Topics: Anesthesia, Epidural; Atenolol; Bradycardia; Heart Block; Humans; Hypotension; Isoproterenol; Male;

1994
Pulmonary hypertension is a contraindication to beta-blockade in patients with severe mitral stenosis.
    American heart journal, 1993, Volume: 125, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Cardiac Catheterization; Cardiac Output; Catheterizati

1993
Mechanisms mediating insulin-induced hypotension in rats. A role for nitric oxide and autonomic mediators.
    Acta diabetologica, 1996, Volume: 33, Issue:4

    Topics: Animals; Antihypertensive Agents; Atenolol; Atropine; Autonomic Nervous System; Blood Glucose; Blood

1996
A 9-year-old girl with chronic fatigue. Diagnosis: neurally mediated hypotension.
    European journal of pediatrics, 1999, Volume: 158, Issue:9

    Topics: Adrenergic beta-Antagonists; Atenolol; Child; Electrocardiography; Fatigue Syndrome, Chronic; Female

1999
Hypotension in patients with coronary disease: can profound hypotensive events cause myocardial ischaemic events?
    Heart (British Cardiac Society), 1999, Volume: 82, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Blood Pressure Monitoring, Amb

1999
In vivo evidence that isoproterenol may increase heart rate in the rat by mechanisms in addition to activation of cardiac beta(1)- or beta(2)-adrenoceptors.
    European journal of pharmacology, 1999, Oct-15, Volume: 382, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Biological Clocks; Drug In

1999
Aminophylline reversal of antihypertensive agent toxicity.
    Veterinary and human toxicology, 2001, Volume: 43, Issue:5

    Topics: Adrenergic beta-Antagonists; Aminophylline; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Card

2001
Atenolol induced hypotension.
    The Journal of the Association of Physicians of India, 1991, Volume: 39, Issue:3

    Topics: Adult; Atenolol; Female; Humans; Hypertension; Hypotension

1991
Profound hypotension after atenolol in severe hypertension.
    BMJ (Clinical research ed.), 1989, Jan-21, Volume: 298, Issue:6667

    Topics: Adult; Atenolol; Female; Humans; Hypertension, Malignant; Hypotension; Middle Aged

1989
Changes in plasma catecholamines and plasma renin activity during hypotension in conscious rats with lesions of the nucleus tractus solitarii.
    Journal of the autonomic nervous system, 1988, Volume: 22, Issue:2

    Topics: Animals; Atenolol; Blood Pressure; Cardiovascular System; Consciousness; Denervation; Electric Stimu

1988
Prolonged bradycardia and hypotension after neostigmine administration in a patient receiving atenolol.
    Anaesthesia, 1987, Volume: 42, Issue:12

    Topics: Aged; Atenolol; Bradycardia; Drug Interactions; Female; Humans; Hypotension; Neostigmine; Pancuroniu

1987
Atenolol overdosage in a patient with progressive renal failure.
    The Western journal of medicine, 1986, Volume: 145, Issue:1

    Topics: Atenolol; Bradycardia; Humans; Hypotension; Kidney Diseases; Male; Middle Aged

1986
Severe atenolol poisoning: treatment with prenalterol.
    Human toxicology, 1986, Volume: 5, Issue:5

    Topics: Atenolol; Bradycardia; Female; Humans; Hypotension; Middle Aged; Prenalterol

1986
Prolonged toxicity from atenolol overdose in an adolescent.
    Clinical pharmacy, 1986, Volume: 5, Issue:10

    Topics: Adolescent; Atenolol; Bradycardia; Female; Humans; Hypoglycemia; Hypotension; Suicide, Attempted

1986