Page last updated: 2024-10-23

atenolol and Hypertriglyceridemia

atenolol has been researched along with Hypertriglyceridemia in 4 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Hypertriglyceridemia: A condition of elevated levels of TRIGLYCERIDES in the blood.

Research Excerpts

ExcerptRelevanceReference
"We assessed adverse metabolic effects of atenolol and hydrochlorothiazide among hypertensive patients with and without abdominal obesity using data from a randomized, open-label study of hypertensive patients without evidence of cardiovascular disease or diabetes mellitus."5.14Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications. ( Beitelshees, AL; Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Gong, Y; Gums, JG; Hall, K; Johnson, JA; Parekh, V; Turner, ST; Wen, S; Zineh, I, 2010)
" In the light of the results obtained, the following conclusions were drawn: 1) hyperlipidemia affects pharmacodynamic properties of lipophilic propranolol and hydrophilic atenolol, 2) a modification of the drug dosage in hyperlipidemia is warranted."2.71[Effect of hyperlipidemia on pharmacodynamics of propranolol and atenolol]. ( Droździk, M; Gawrońska-Szklarz, B; Sterna, R; Sulzyc-Bielicka, V; Telatyńska-Smieszek, B; Wójcicki, J, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manrique, C1
Johnson, M1
Sowers, JR1
Cooper-DeHoff, RM1
Wen, S1
Beitelshees, AL1
Zineh, I1
Gums, JG1
Turner, ST1
Gong, Y1
Hall, K1
Parekh, V1
Chapman, AB1
Boerwinkle, E1
Johnson, JA1
Telatyńska-Smieszek, B1
Wójcicki, J1
Droździk, M1
Gawrońska-Szklarz, B1
Sulzyc-Bielicka, V1
Sterna, R1
Haitas, B1
Disler, LJ1
Joffe, BI1
Seftel, HC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR)[NCT00246519]Phase 41,701 participants (Actual)Interventional2005-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Blood Pressure Response (Delta BP (After 18 Weeks of Medication - Baseline)).

(NCT00246519)
Timeframe: baseline to 18 weeks of treatment

InterventionmmHg (Mean)
Atenolol +HCTZ Arm-12.06
HCTZ + Atenolol-13.33

Trials

2 trials available for atenolol and Hypertriglyceridemia

ArticleYear
Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Diabetes Mellitus; Drug Therapy, Combina

2010
[Effect of hyperlipidemia on pharmacodynamics of propranolol and atenolol].
    Polskie Archiwum Medycyny Wewnetrznej, 2004, Volume: 111, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Area Under Curve; Atenolol; Blood Pressure; Chrom

2004

Other Studies

2 other studies available for atenolol and Hypertriglyceridemia

ArticleYear
Thiazide diuretics alone or with beta-blockers impair glucose metabolism in hypertensive patients with abdominal obesity.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adrenergic beta-Antagonists; Atenolol; Diabetes Mellitus; Diuretics; Drug Therapy, Combination; Fast

2010
Massive hypertriglyceridemia associated with atenolol.
    The American journal of medicine, 1988, Volume: 85, Issue:4

    Topics: Adult; Atenolol; Humans; Hypertriglyceridemia; Male; Middle Aged

1988