Page last updated: 2024-10-23

atenolol and Death, Sudden, Cardiac

atenolol has been researched along with Death, Sudden, Cardiac in 17 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)

Research Excerpts

ExcerptRelevanceReference
"To investigate the actions of beta-blocker (atenolol) and ACE inhibitor (enalapril) for the secondary prevention of the main cardiac complications after acute myocardial infarction (AMI)."9.08Secondary prevention of cardiac events following myocardial infarction: effects of atenolol and enalapril. Beijing Collaborative Study Group. ( Fan, Z; Wu, N, 1997)
"The Losartan Intervention for End Point Reduction in Hypertension (LIFE) study included 9193 patients 55 to 80 years of age with essential hypertension and ECG LV hypertrophy by gender-adjusted Cornell product (CP) (RaVL+SV(3) [+6 mm in women])."5.12Regression of electrocardiographic left ventricular hypertrophy during antihypertensive therapy and reduction in sudden cardiac death: the LIFE Study. ( Dahlöf, B; Devereux, RB; Ibsen, H; Kjeldsen, SE; Lindholm, LH; Nieminen, MS; Okin, PM; Olsen, MH; Thygesen, K; Wachtell, K, 2007)
"To investigate the actions of beta-blocker (atenolol) and ACE inhibitor (enalapril) for the secondary prevention of the main cardiac complications after acute myocardial infarction (AMI)."5.08Secondary prevention of cardiac events following myocardial infarction: effects of atenolol and enalapril. Beijing Collaborative Study Group. ( Fan, Z; Wu, N, 1997)
"In the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study, a major reduction of all-cause mortality--especially cardiovascular mortality--in patients with diabetes with left ventricular hypertrophy was reported for treatment with losartan."3.72Effect of losartan on sudden cardiac death in people with diabetes: data from the LIFE study. ( Borch-Johnsen, K; Dahlöf, B; Edelman, JM; Ibsen, H; Lindholm, LH; Olsen, MH; Snapinn, S; Wachtell, K, 2003)
"Baroreflex sensitivity was assessed in 287 patients with history of myocardial infarction and left ventricular ejection fraction < or =40% by phenylephrine test and was found to be depressed (4."3.72[Correction of baroreflex sensitivity impairment and efficacy of prevention of sudden arrhythmic death in patients with postinfarction left ventricular dysfunction]. ( Bozhko, AA; Kanopskiĭ, SG; Staritskiĭ, AG, 2004)
"The patient had no further arrhythmias on quinidine for 6 years until he inexplicably discontinued his medication and died suddenly shortly thereafter."1.30Familial sudden cardiac death associated with a terminal QRS abnormality on surface 12-lead electrocardiogram in the index case. ( Feld, GK; Finneran, W; Garg, A, 1998)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (47.06)18.2507
2000's7 (41.18)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reno, CM1
Skinner, A1
Bayles, J1
Chen, YS1
Daphna-Iken, D1
Fisher, SJ1
Abu-Zeitone, A1
Peterson, DR1
Polonsky, B1
McNitt, S1
Moss, AJ1
Morin, DP1
Oikarinen, L1
Viitasalo, M1
Toivonen, L1
Nieminen, MS2
Kjeldsen, SE2
Dahlöf, B3
John, M1
Devereux, RB2
Okin, PM2
Aronow, WS1
Lindholm, LH2
Edelman, JM1
Ibsen, H2
Borch-Johnsen, K1
Olsen, MH2
Snapinn, S1
Wachtell, K2
Ong, HT1
Chong, AY1
Lip, GY1
Kanopskiĭ, SG1
Staritskiĭ, AG1
Bozhko, AA1
Thygesen, K1
Adamson, PB1
Huang, MH1
Vanoli, E1
Foreman, RD1
Schwartz, PJ1
Hull, SS1
Raza, A1
Killip, T1
Goodman, S1
Hill, C1
Bata, I1
Fung, A1
Higginson, L1
Lam, J1
Massel, D1
McCans, J1
Nasmith, J1
Stanton, E1
Thompson, C1
Warnica, W1
Langer, A1
Lurje, L1
Wennerblom, B1
Tygesen, H1
Karlsson, T1
Hjalmarson, A1
Wu, N1
Fan, Z1
Garg, A1
Finneran, W1
Feld, GK1
Koudstaal, PJ1
Algra, A1
Pop, GA1
Kappelle, LJ1
van Latum, JC1
van Gijn, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessment of Prolonged Paced QRS Duration as a Marker of Sudden Cardiac Death in Subjects With Implantable Cardioverter-defibrillators[NCT01948206]100 participants (Actual)Observational2013-10-31Terminated (stopped due to Ran out of funds)
A Triple-Blind, Parallel Study to Investigate the Effect of Losartan Versus Atenolol on the Reduction of Morbidity and Mortality in Hypertensive Patients With Left Ventricular Hypertrophy[NCT00338260]Phase 3496 participants (Actual)Interventional1995-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

6 trials available for atenolol and Death, Sudden, Cardiac

ArticleYear
QRS duration predicts sudden cardiac death in hypertensive patients undergoing intensive medical therapy: the LIFE study.
    European heart journal, 2009, Volume: 30, Issue:23

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Atenolol; Bundle-Branch Block; Death, Sudden, Card

2009
Regression of electrocardiographic left ventricular hypertrophy during antihypertensive therapy and reduction in sudden cardiac death: the LIFE Study.
    Circulation, 2007, Aug-14, Volume: 116, Issue:7

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Atenolol; Death, Sudden, Cardiac; Double-Blind Met

2007
PROTECT (Prospective Reinfarction Outcomes in the Thrombolytic Era Cardizem CD Trial): a randomized, double-blind clinical trial of diltiazem versus atenolol in secondary prophylaxis post non-Q wave myocardial infarction.
    The Canadian journal of cardiology, 1996, Volume: 12, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Calcium Channel Blockers; Death, Sudden, Cardiac; Dilt

1996
Heart rate variability after acute myocardial infarction in patients treated with atenolol and metoprolol.
    International journal of cardiology, 1997, Jul-25, Volume: 60, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Autonomic Nervous System; Cross-Over Studies; De

1997
Secondary prevention of cardiac events following myocardial infarction: effects of atenolol and enalapril. Beijing Collaborative Study Group.
    Chinese medical journal, 1997, Volume: 110, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Cardiac Outpu

1997
Risk of cardiac events in atypical transient ischaemic attack or minor stroke. The Dutch TIA Study Group.
    Lancet (London, England), 1992, Sep-12, Volume: 340, Issue:8820

    Topics: Aged; Aspirin; Atenolol; Cerebrovascular Disorders; Death, Sudden, Cardiac; Diagnosis, Differential;

1992

Other Studies

11 other studies available for atenolol and Death, Sudden, Cardiac

ArticleYear
Severe hypoglycemia-induced sudden death is mediated by both cardiac arrhythmias and seizures.
    American journal of physiology. Endocrinology and metabolism, 2018, 08-01, Volume: 315, Issue:2

    Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmia

2018
Efficacy of different beta-blockers in the treatment of long QT syndrome.
    Journal of the American College of Cardiology, 2014, Sep-30, Volume: 64, Issue:13

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Child; Child, Preschool; Death, Sudden, Ca

2014
Might losartan reduce sudden cardiac death in diabetic patients with hypertension?
    Lancet (London, England), 2003, Aug-23, Volume: 362, Issue:9384

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Clinical Trials as Topic; Comorbidit

2003
Effect of losartan on sudden cardiac death in people with diabetes: data from the LIFE study.
    Lancet (London, England), 2003, Aug-23, Volume: 362, Issue:9384

    Topics: Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Atenolol; Atrial Fibrillation; Comorbidity; Dea

2003
LIFE: losartan versus atenolol.
    Lancet (London, England), 2003, Oct-25, Volume: 362, Issue:9393

    Topics: Antihypertensive Agents; Atenolol; Comorbidity; Death, Sudden, Cardiac; Diabetes Mellitus; Drug Ther

2003
LIFE: losartan versus atenolol.
    Lancet (London, England), 2003, Oct-25, Volume: 362, Issue:9393

    Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Atenolol; Comorbidity; Death, Sudden, Cardiac; Diab

2003
[Correction of baroreflex sensitivity impairment and efficacy of prevention of sudden arrhythmic death in patients with postinfarction left ventricular dysfunction].
    Kardiologiia, 2004, Volume: 44, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti

2004
Unexpected interaction between beta-adrenergic blockade and heart rate variability before and after myocardial infarction. A longitudinal study in dogs at high and low risk for sudden death.
    Circulation, 1994, Volume: 90, Issue:2

    Topics: Animals; Atenolol; Autonomic Nervous System; Death, Sudden, Cardiac; Dogs; Heart; Heart Rate; Longit

1994
Beta-receptor blockade in preventing sudden death.
    European heart journal, 1993, Volume: 14, Issue:5

    Topics: Adrenergic beta-Antagonists; Atenolol; Death, Sudden, Cardiac; Humans; Metoprolol; Practolol; Sotalo

1993
Silent myocardial ischemia: some good news.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Adrenergic beta-Antagonists; Atenolol; Calcium Channel Blockers; Combined Modality Therapy; Coronary

1997
Familial sudden cardiac death associated with a terminal QRS abnormality on surface 12-lead electrocardiogram in the index case.
    Journal of cardiovascular electrophysiology, 1998, Volume: 9, Issue:6

    Topics: Adolescent; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Death, Sudden, Cardiac; Electroc

1998