atenolol has been researched along with Cardiac Hypertrophy in 45 studies
Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To confirm that alpha1, beta adrenoceptor antagonists and angiotensin II type 1 receptor blockers (ARBs) have different abilities to attenuate progressive cardiac hypertrophy despite their comparable lowering of blood pressure, we compared the effect of these agents alone or in combination on hypertensive cardiac hypertrophy." | 7.73 | Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction ( Asai, T; Fujita, H; Kanmatsuse, K; Kushiro, T, 2005) |
| "The stimulus for carbon monoxide-induced cardiac hypertrophy was investigated." | 7.68 | Carbon monoxide-induced cardiac hypertrophy is not reduced by alpha- or beta-blockade in the rat. ( Formolo, JM; Penney, DG, 1993) |
| " Therefore, M-mode and Doppler techniques were used to assess changes in LV hypertrophy after 10, 30 and 50 weeks of atenolol therapy (50 or 100 mg once daily) in 19 patients with essential hypertension." | 7.67 | Effects of atenolol on left ventricular hypertrophy and early left ventricular function in essential hypertension. ( Allen, JW; Kaiser, PJ; Montenegro, A, 1989) |
| " Seventeen male patients with essential hypertension were studied after 4 weeks of placebo and after 8 weeks of beta-adrenoceptor-blockade therapy with atenolol (100 mg/kg)." | 5.05 | Factors influencing cardiac hypertrophy in hypertensive patients. ( Ibrahim, MM; Madkour, MA; Mossallam, R, 1981) |
| "To confirm that alpha1, beta adrenoceptor antagonists and angiotensin II type 1 receptor blockers (ARBs) have different abilities to attenuate progressive cardiac hypertrophy despite their comparable lowering of blood pressure, we compared the effect of these agents alone or in combination on hypertensive cardiac hypertrophy." | 3.73 | Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction ( Asai, T; Fujita, H; Kanmatsuse, K; Kushiro, T, 2005) |
| " Atenolol neither modified HR nor BP variability in rats with hyperthyroidism." | 3.70 | Autonomic contribution to the blood pressure and heart rate variability changes in early experimental hyperthyroidism. ( Elghozi, JL; Laude, D; Ponchon, P; Safa-Tisseront, V, 1998) |
| "The stimulus for carbon monoxide-induced cardiac hypertrophy was investigated." | 3.68 | Carbon monoxide-induced cardiac hypertrophy is not reduced by alpha- or beta-blockade in the rat. ( Formolo, JM; Penney, DG, 1993) |
| "Twenty-one patients with previously untreated essential hypertension were treated with a low dose combination of 50 mg of atenolol and 10 mg of enalapril once daily for 39 months." | 3.68 | Preserved ventricular pump function after a marked reduction of left ventricular mass. ( Behr, U; Franz, IW; Ketelhut, R; Messerli, FH; Toennesmann, U, 1992) |
| " Therefore, M-mode and Doppler techniques were used to assess changes in LV hypertrophy after 10, 30 and 50 weeks of atenolol therapy (50 or 100 mg once daily) in 19 patients with essential hypertension." | 3.67 | Effects of atenolol on left ventricular hypertrophy and early left ventricular function in essential hypertension. ( Allen, JW; Kaiser, PJ; Montenegro, A, 1989) |
| " We obtained echocardiograms at baseline and serially (on seven occasions) during a 1 year treatment period with the beta-adrenergic receptor inhibitor atenolol in 12 patients with previously untreated essential hypertension." | 3.67 | Time course of regression of left ventricular hypertrophy in hypertensive patients treated with atenolol. ( Dunn, FG; Frohlich, ED; Kobrin, I; Messerli, FH; Ventura, HO, 1987) |
| "Atenolol did not produce a reduction in the left-ventricular-mass index (109 +/- 9 g per square meter before treatment vs." | 2.67 | The effects of antihypertensive therapy on left ventricular mass in elderly patients. ( Becker, LC; Gerstenblith, G; Gottlieb, SO; Schulman, SP; Weisfeldt, ML; Weiss, JL; Woodruff, KM, 1990) |
| "Metoprolol treatment produced a slight but significant reduction in serum glucose levels with elevation in serum insulin levels, while atenolol produced a slight increase in glucose levels but no effect on insulin levels." | 1.34 | Comparative evaluation of atenolol and metoprolol on cardiovascular complications associated with streptozotocin-induced diabetic rats. ( Bhadada, SV; Goyal, RK, 2007) |
| "Atenolol was injected subcutaneously (20 mg/kg) twice daily commencing in four-week-old rats." | 1.27 | The effects of beta adrenoceptor blockade with atenolol on myocardial cellular and subcellular hypertrophy in spontaneously hypertensive rats. ( Lauva, IK; Tomanek, RJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (48.89) | 18.7374 |
| 1990's | 14 (31.11) | 18.2507 |
| 2000's | 5 (11.11) | 29.6817 |
| 2010's | 3 (6.67) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Mohamed, RMSM | 1 |
| Elshazly, SM | 1 |
| Nafea, OE | 1 |
| Abd El Motteleb, DM | 1 |
| Ling, S | 1 |
| Nanhwan, M | 1 |
| Qian, J | 1 |
| Kodakandla, M | 1 |
| Castillo, AC | 1 |
| Thomas, B | 1 |
| Liu, H | 1 |
| Ye, Y | 1 |
| Wachtell, K | 1 |
| Gerdts, E | 1 |
| Aurigemma, GP | 1 |
| Boman, K | 1 |
| Dahlöf, B | 1 |
| Nieminen, MS | 1 |
| Olsen, MH | 1 |
| Okin, PM | 1 |
| Palmieri, V | 1 |
| Rokkedal, JE | 1 |
| Devereux, RB | 1 |
| Wang, Q | 1 |
| Maillard, M | 1 |
| Schibler, U | 1 |
| Burnier, M | 1 |
| Gachon, F | 1 |
| Asai, T | 1 |
| Kushiro, T | 1 |
| Fujita, H | 1 |
| Kanmatsuse, K | 1 |
| Yokoyama, H | 1 |
| Averill, DB | 1 |
| Brosnihan, KB | 1 |
| Smith, RD | 1 |
| Schiffrin, EL | 1 |
| Ferrario, CM | 1 |
| Bhadada, SV | 1 |
| Goyal, RK | 1 |
| Lauva, IK | 1 |
| Tomanek, RJ | 1 |
| Shkhvatsabaia, IK | 2 |
| Dennis, P | 1 |
| Vaughan Williams, EM | 2 |
| Loaldi, A | 1 |
| Pepi, M | 1 |
| Agostoni, PG | 1 |
| Fiorentini, C | 1 |
| Grazi, S | 1 |
| Della Bella, P | 1 |
| Guazzi, MD | 1 |
| Ibrahim, MM | 1 |
| Madkour, MA | 1 |
| Mossallam, R | 1 |
| Giudicelli, JF | 1 |
| Freslon, JL | 1 |
| Richer, C | 1 |
| Penney, DG | 1 |
| Formolo, JM | 1 |
| Safa-Tisseront, V | 1 |
| Ponchon, P | 1 |
| Laude, D | 1 |
| Elghozi, JL | 1 |
| Shantz, LM | 1 |
| Feith, DJ | 1 |
| Pegg, AE | 1 |
| Uusimaa, P | 1 |
| Tokola, H | 1 |
| Ruskoaho, H | 1 |
| Vuolteenaho, O | 1 |
| Risteli, J | 1 |
| Ylitalo, A | 1 |
| Peuhkurinen, K | 1 |
| Strauer, BE | 1 |
| Ketelhut, R | 5 |
| Franz, IW | 5 |
| Behr, U | 5 |
| Toennesmann, U | 1 |
| Messerli, FH | 2 |
| González-Juanatey, JR | 1 |
| Amaro Cendón, A | 1 |
| Calvo Gómez, C | 1 |
| Vega Fernández, M | 1 |
| García Acuña, JM | 1 |
| Virgós Lamela, A | 1 |
| Gil de la Peña, M | 1 |
| Otterstad, JE | 1 |
| Froeland, G | 1 |
| Wasenius Soeyland, AK | 1 |
| Knutsen, KM | 1 |
| Ekeli, T | 1 |
| Tanaka, H | 1 |
| Obata, H | 1 |
| Haneda, T | 1 |
| Head, GA | 1 |
| Minami, N | 1 |
| Adams, MA | 1 |
| Bobik, A | 1 |
| Cai, B | 1 |
| Schulman, SP | 2 |
| Weiss, JL | 1 |
| Becker, LC | 1 |
| Gottlieb, SO | 1 |
| Woodruff, KM | 1 |
| Weisfeldt, ML | 1 |
| Gerstenblith, G | 3 |
| Tönnesmann, U | 4 |
| Baglivo, HP | 1 |
| Fabregues, G | 1 |
| Burrieza, HO | 1 |
| Marín, M | 1 |
| Esper, RJ | 1 |
| Allen, JW | 1 |
| Kaiser, PJ | 1 |
| Montenegro, A | 1 |
| Lindpaintner, K | 1 |
| Sen, S | 3 |
| Iurenev, AP | 1 |
| Charyev, KhE | 1 |
| Young, DR | 1 |
| Vogt, M | 1 |
| Ott, B | 1 |
| Rupp, H | 1 |
| Jacob, R | 1 |
| Dunn, FG | 1 |
| Ventura, HO | 1 |
| Kobrin, I | 1 |
| Frohlich, ED | 1 |
| Fogari, R | 1 |
| Zoppi, A | 1 |
| Poletti, L | 1 |
| Tettamanti, F | 1 |
| Orlandi, C | 1 |
| Grover-McKay, M | 1 |
| Matsuzaki, M | 1 |
| Ross, J | 1 |
| Mohallen, KL | 1 |
| do Patrocínio, LL | 1 |
| Célnik, D | 1 |
| Kruczan, DD | 1 |
| Pinheiro, L | 1 |
| Weitzel, LH | 1 |
| Bosco, J | 1 |
| Sekeff, JA | 1 |
| Azevedo, Ade C | 1 |
| Trimarco, B | 1 |
| Ricciardelli, B | 1 |
| De Luca, N | 1 |
| De Simone, A | 1 |
| Cuocolo, A | 1 |
| Galva, MD | 1 |
| Picotti, GB | 1 |
| Condorelli, M | 1 |
2 reviews available for atenolol and Cardiac Hypertrophy
| Article | Year |
|---|---|
[Course of hypertension and the potentials for regression].
Topics: Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiomegaly; Diuretics; Heart; Humans; | 1982 |
[Cardiac function in hypertension].
Topics: Atenolol; Cardiomegaly; Coronary Disease; Digitalis Glycosides; Heart Function Tests; Heart Valve Di | 1978 |
9 trials available for atenolol and Cardiac Hypertrophy
| Article | Year |
|---|---|
Factors influencing cardiac hypertrophy in hypertensive patients.
Topics: Adult; Atenolol; Cardiomegaly; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Receptors, Adr | 1981 |
[Regression of left ventricular mass in arterial hypertension. Efficacy of 3 different treatment protocols].
Topics: Adult; Aged; Atenolol; Blood Pressure; Cardiomegaly; Chlorthalidone; Electrocardiography; Enalapril; | 1992 |
Changes in left ventricular dimensions and systolic function in 100 mildly hypertensive men during one year's treatment with atenolol vs. hydrochlorothiazide and amiloride (Moduretic): a double-blind, randomized study.
Topics: Adult; Aged; Atenolol; Cardiomegaly; Double-Blind Method; Echocardiography; Humans; Hydrochlorothiaz | 1992 |
The effects of antihypertensive therapy on left ventricular mass in elderly patients.
Topics: Atenolol; Blood Pressure; Cardiomegaly; Double-Blind Method; Echocardiography; Gated Blood-Pool Imag | 1990 |
[Regression of left ventricular hypertrophy in hypertensive patients under long-term therapy with antihypertensive agents].
Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Female; Gallopamil; Humans; Hype | 1990 |
Influence of left ventricular mass regression on cardiac function in hypertensive elderly individuals.
Topics: Aged; Atenolol; Cardiomegaly; Double-Blind Method; Humans; Hypertension; Middle Aged; Physical Exert | 1990 |
Special considerations in the elderly patient.
Topics: Age Factors; Aged; Aging; Atenolol; Blood Pressure; Cardiac Output; Cardiomegaly; Chlorthalidone; Do | 1990 |
[Regression of left heart hypertrophy in hypertensive patients as a result of antihypertensive therapy].
Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiac Output; Cardiac Volume; Cardiomegaly; | 1989 |
[Normalization of ventricular compliance and hypertrophy in arterial hypertension. Double-blind study with 2 combinations of a beta blocker and diuretic].
Topics: Adult; Atenolol; Blood Pressure; Cardiomegaly; Chlorthalidone; Clinical Trials as Topic; Double-Blin | 1987 |
34 other studies available for atenolol and Cardiac Hypertrophy
| Article | Year |
|---|---|
Comparative cardioprotective effects of carvedilol versus atenolol in a rat model of cardiorenal syndrome type 4.
Topics: Animals; Apoptosis; Atenolol; beta-Arrestin 2; Blood Pressure; Cardio-Renal Syndrome; Cardiomegaly; | 2021 |
Modulation of microRNAs in hypertension-induced arterial remodeling through the β1 and β3-adrenoreceptor pathways.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Atenolol; Atrial Remodeling; Benzopyrans; Cardiomegaly; | 2013 |
In-treatment reduced left atrial diameter during antihypertensive treatment is associated with reduced new-onset atrial fibrillation in hypertensive patients with left ventricular hypertrophy: The LIFE Study.
Topics: Aged; Antihypertensive Agents; Arrhythmias, Cardiac; Atenolol; Atrial Fibrillation; Blood Pressure; | 2010 |
Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF.
Topics: Adrenergic beta-Antagonists; Aldosterone; Animals; Atenolol; Basic-Leucine Zipper Transcription Fact | 2010 |
Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin II Type 1 Rec | 2005 |
Role of blood pressure reduction in prevention of cardiac and vascular hypertrophy.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; | 2005 |
Comparative evaluation of atenolol and metoprolol on cardiovascular complications associated with streptozotocin-induced diabetic rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Glucose; Blood Pressure; Cardiomegaly; Cardiov | 2007 |
The effects of beta adrenoceptor blockade with atenolol on myocardial cellular and subcellular hypertrophy in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Body Water; Body Weight; Cardiomegal | 1983 |
Hypoxic cardiac hypertrophy is not inhibited by cardioselective or non-selective beta-adrenoceptor antagonists.
Topics: Animals; Atenolol; Body Water; Cardiomegaly; Female; Heart Atria; Heart Ventricles; Hypoxia; Male; M | 1982 |
Cardiac rhythm in hypertension assessed through 24 hour ambulatory electrocardiographic monitoring. Effects of load manipulation with atenolol, verapamil, and nifedipine.
Topics: Adult; Atenolol; Cardiomegaly; Echocardiography; Electrocardiography; Female; Heart Conduction Syste | 1983 |
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Re | 1980 |
Carbon monoxide-induced cardiac hypertrophy is not reduced by alpha- or beta-blockade in the rat.
Topics: Animals; Atenolol; Blood Pressure; Body Weight; Carbon Monoxide; Cardiomegaly; Heart Rate; Lung; Mal | 1993 |
Autonomic contribution to the blood pressure and heart rate variability changes in early experimental hyperthyroidism.
Topics: Animals; Atenolol; Atropine; Autonomic Nervous System; Blood Pressure; Cardiomegaly; Disease Models, | 1998 |
Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Atenolol; Blotting, Southern; Cadaverine; Cardiomegaly; Hypertrop | 2001 |
Vasoactive peptides and procollagen propeptides in patients with hypertension in relation to cardiac hypertrophy and diastolic heart failure: design of the study and patient characteristics.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Atrial Natriuretic Factor; Bendroflumethiazide; Cardi | 2001 |
Preserved ventricular pump function after a marked reduction of left ventricular mass.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Blood Pressu | 1992 |
Effects of regression of left ventricular hypertrophy following atenolol or bunazosin therapy on ischemic cardiac function and myocardial metabolism in spontaneously hypertensive rats.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Atenolol; Blood Pre | 1991 |
Development of cardiac hypertrophy and its relationship to the cardiac baroreflex deficit in hypertension.
Topics: Animals; Antihypertensive Agents; Atenolol; Atropine; Blood Pressure; Cardiomegaly; Heart Rate; Hype | 1991 |
[The effect of lowered pressure on the diastolic ventricular function after antihypertensive treatment].
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Cardiomegaly; Diastole; Female; | 1991 |
Left ventricular hypertrophy in hypertension.
Topics: Aged; Atenolol; Cardiomegaly; Humans; Hypertension; Middle Aged; Placebos; Verapamil | 1990 |
[Reduction of the left ventricular mass in essential hypertension patients chronically treated with monotherapy].
Topics: Adult; Atenolol; Blood Pressure; Cardiomegaly; Drug Administration Schedule; Enalapril; Female; Huma | 1990 |
Ventricular hypertrophy--physiological mechanisms.
Topics: Action Potentials; Animals; Atenolol; Cardiomegaly; Eating; Growth; Hypoxia; Membrane Potentials; Or | 1986 |
Effects of atenolol on left ventricular hypertrophy and early left ventricular function in essential hypertension.
Topics: Adult; Aged; Atenolol; Blood Pressure; Capillary Resistance; Cardiac Output; Cardiomegaly; Echocardi | 1989 |
Role of beta 1-adrenoceptors in hypertensive cardiac hypertrophy.
Topics: Animals; Atenolol; Cardiomegaly; Catecholamines; Hemodynamics; Hypertension, Renovascular; Male; Myo | 1987 |
[Regression of left-ventricular myocardial hypertrophy in patients with hypertension during long-term treatment with beta-adrenergic blockaders].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Drug Therapy, C | 1986 |
Role of sodium in modulation of myocardial hypertrophy in renal hypertensive rats.
Topics: Animals; Atenolol; Captopril; Cardiomegaly; Diet, Sodium-Restricted; Hypertension, Renovascular; Iso | 1986 |
Significance of physical exercise in hypertension. Influence of water temperature and beta-blockade on blood pressure, degree of cardiac hypertrophy and cardiac function in swimming training of spontaneously hypertensive rats.
Topics: Animals; Atenolol; Blood Pressure; Cardiomegaly; Heart; Hypertension; Male; Physical Exertion; Rats; | 1986 |
Factors regulating myocardial hypertrophy in hypertension.
Topics: Animals; Atenolol; Blood Pressure; Captopril; Cardiomegaly; Hypertension; Isoenzymes; Male; Myocardi | 1987 |
Time course of regression of left ventricular hypertrophy in hypertensive patients treated with atenolol.
Topics: Adult; Atenolol; Cardiomegaly; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Hum | 1987 |
Chronic beta 1-blockade and control of left ventricular hypertrophy in hypertension.
Topics: Adult; Arrhythmias, Cardiac; Atenolol; Blood Pressure; Cardiomegaly; Electrocardiography; Female; Hu | 1987 |
Dissociation between regional myocardial dysfunction and subendocardial ST segment elevation during and after exercise-induced ischemia in dogs.
Topics: Animals; Atenolol; Blood Pressure; Cardiomegaly; Coronary Circulation; Coronary Disease; Dogs; Elect | 1987 |
Long-term effect of antihypertensive therapy on left ventricular hypertrophy.
Topics: Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Drug Therapy, Combination; Echocardiography; | 1987 |
Regression of left ventricular hypertrophy during combined atenolol and nifedipine treatment.
Topics: Adult; Atenolol; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Exercise | 1988 |
Participation of endogenous catecholamines in the regulation of left ventricular mass in progeny of hypertensive parents.
Topics: Adolescent; Adult; Aldosterone; Atenolol; Blood Pressure; Blood Volume; Body Weight; Cardiomegaly; C | 1985 |