Page last updated: 2024-10-23

atenolol and Brain Ischemia

atenolol has been researched along with Brain Ischemia in 6 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"This work aims at studying the possible alteration of renal renin secretion after human ischemic stroke and correlating it to the post stroke neurological and renal function alterations using angiotensin II type 1(AT1) receptor blocker (ARB), candesartan, and beta 1 adrenoreceptor blocker atenolol, which inhibits renin secretion, in Wistar rats subjected to middle cerebral artery occlusion."7.76Effect of angiotensin II type 1 receptor blocker, candesartan, and beta 1 adrenoceptor blocker, atenolol, on brain damage in ischemic stroke. ( Abbas, AM; Boshra, V; El Aal, IA; Elkhateeb, M; Saad, MA, 2010)
"This work aims at studying the possible alteration of renal renin secretion after human ischemic stroke and correlating it to the post stroke neurological and renal function alterations using angiotensin II type 1(AT1) receptor blocker (ARB), candesartan, and beta 1 adrenoreceptor blocker atenolol, which inhibits renin secretion, in Wistar rats subjected to middle cerebral artery occlusion."3.76Effect of angiotensin II type 1 receptor blocker, candesartan, and beta 1 adrenoceptor blocker, atenolol, on brain damage in ischemic stroke. ( Abbas, AM; Boshra, V; El Aal, IA; Elkhateeb, M; Saad, MA, 2010)
"4 mg/kg by intraperitoneal injection Animals were dosed once every 2 hr for a total of five doses."1.28Nonlinear distribution of atenolol between plasma and cerebrospinal fluid. ( Fagan, SC; Gengo, FM; Hopkins, LN; Schuster, DP; Wagner, D, 1989)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saad, MA1
Abbas, AM1
Boshra, V1
Elkhateeb, M1
El Aal, IA1
Gulliksen, G1
Højer-Pedersen, E1
Møller, M1
Harvald, B1
Enevoldsen, E1
Davis, BR2
Vogt, T1
Frost, PH1
Burlando, A1
Cohen, J1
Wilson, A1
Brass, LM1
Frishman, W1
Price, T1
Stamler, J2
Perry, HM1
Price, TR1
Applegate, WB1
Fields, WS1
Guralnik, JM1
Kuller, L1
Pressel, S1
Probstfield, JL1
Bednar, MM1
Gross, CE1
Howard, DB1
Russell, SR1
Ellenberger, C1
Gengo, FM1
Fagan, SC1
Hopkins, LN1
Wagner, D1
Schuster, DP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000514]Phase 30 participants Interventional1984-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for atenolol and Brain Ischemia

ArticleYear
Risk factors for stroke and type of stroke in persons with isolated systolic hypertension. Systolic Hypertension in the Elderly Program Cooperative Research Group.
    Stroke, 1998, Volume: 29, Issue:7

    Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Brain Ischemia; Cerebral Hemorrhage; Cerebr

1998
Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke: the Systolic Hypertension in the Elderly Program (SHEP).
    JAMA, 2000, Jul-26, Volume: 284, Issue:4

    Topics: Aged; Antihypertensive Agents; Atenolol; Brain Ischemia; Cerebral Hemorrhage; Chlorthalidone; Double

2000

Other Studies

4 other studies available for atenolol and Brain Ischemia

ArticleYear
Effect of angiotensin II type 1 receptor blocker, candesartan, and beta 1 adrenoceptor blocker, atenolol, on brain damage in ischemic stroke.
    Acta physiologica Hungarica, 2010, Volume: 97, Issue:2

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor

2010
Autoregulation of cerebral blood flow in patients with malignant hypertension and hypertensive encephalopathy.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 678

    Topics: Adult; Atenolol; Brain Diseases; Brain Ischemia; Cerebrovascular Circulation; Homeostasis; Humans; H

1983
The effect of vasodilators on aspirin-induced antagonism of t-PA thrombolysis.
    Neurological research, 2001, Volume: 23, Issue:7

    Topics: Animals; Antihypertensive Agents; Aspirin; Atenolol; Brain Ischemia; Cerebrovascular Circulation; Dr

2001
Nonlinear distribution of atenolol between plasma and cerebrospinal fluid.
    Pharmaceutical research, 1989, Volume: 6, Issue:3

    Topics: Animals; Atenolol; Brain; Brain Ischemia; Humans; Rats

1989