Page last updated: 2024-10-23

atenolol and Arteriosclerosis

atenolol has been researched along with Arteriosclerosis in 21 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research Excerpts

ExcerptRelevanceReference
"In the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study, there was a 25% risk reduction for stroke with angiotensin receptor blocker-based therapy (losartan) as compared with beta-blocker-based therapy (atenolol) despite comparable blood pressure reductions."9.12Long-term effects of a losartan- compared with an atenolol-based treatment regimen on carotid artery plaque development in hypertensive patients with left ventricular hypertrophy: ICARUS, a LIFE substudy. ( Fossum, E; Høieggen, A; Ibsen, H; Julius, S; Kjeldsen, SE; Olsen, MH; Reims, HM; Wachtell, K; Wan, Y, 2006)
"The European Lacidipine Study on Atherosclerosis (ELSA) is a prospective, randomized, double-blind, multinational trial comparing effects of 4-year treatment based on the long-acting, highly lipophilic calcium antagonist lacidipine with those of treatment based on the beta-blocker atenolol on the development of carotid artery wall alterations in patients (aged 45-75 years) with mild-to-moderate hypertension (systolic blood pressure 150-210 mmHg and diastolic blood pressure 95-115 mmHg)."9.08Risk factors associated with alterations in carotid intima-media thickness in hypertension: baseline data from the European Lacidipine Study on Atherosclerosis. ( Bond, MG; Dal Palù, C; Eckes, L; Hansson, L; Hennig, M; Magnani, B; Mancia, G; Neiss, A; Rahn, KH; Ravinetto, R; Reid, J; Rodicio, J; Safar, M; Zanchetti, A, 1998)
"The effects of SQ29,852 (n = 24), a new angiotensin converting enzyme inhibitor, and atenolol (n = 22), monotherapies were compared in 46 patients with mild to moderate essential hypertension."9.07Hypotensive effects and influence on serum lipids of SQ29,852, a new angiotensin converting enzyme inhibitor, in patients with essential hypertension: a comparison with atenolol. ( Doi, Y; Kagimoto, M; Kato, K; Kawasaki, K; Koga, S; Sakai, K; Sakaue, A; Sasaki, J; Takada, K; Takii, M, 1993)
"In the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study, there was a 25% risk reduction for stroke with angiotensin receptor blocker-based therapy (losartan) as compared with beta-blocker-based therapy (atenolol) despite comparable blood pressure reductions."5.12Long-term effects of a losartan- compared with an atenolol-based treatment regimen on carotid artery plaque development in hypertensive patients with left ventricular hypertrophy: ICARUS, a LIFE substudy. ( Fossum, E; Høieggen, A; Ibsen, H; Julius, S; Kjeldsen, SE; Olsen, MH; Reims, HM; Wachtell, K; Wan, Y, 2006)
"The European Lacidipine Study on Atherosclerosis (ELSA) is a prospective, randomized, double-blind, multinational trial comparing effects of 4-year treatment based on the long-acting, highly lipophilic calcium antagonist lacidipine with those of treatment based on the beta-blocker atenolol on the development of carotid artery wall alterations in patients (aged 45-75 years) with mild-to-moderate hypertension (systolic blood pressure 150-210 mmHg and diastolic blood pressure 95-115 mmHg)."5.08Risk factors associated with alterations in carotid intima-media thickness in hypertension: baseline data from the European Lacidipine Study on Atherosclerosis. ( Bond, MG; Dal Palù, C; Eckes, L; Hansson, L; Hennig, M; Magnani, B; Mancia, G; Neiss, A; Rahn, KH; Ravinetto, R; Reid, J; Rodicio, J; Safar, M; Zanchetti, A, 1998)
"The effects of SQ29,852 (n = 24), a new angiotensin converting enzyme inhibitor, and atenolol (n = 22), monotherapies were compared in 46 patients with mild to moderate essential hypertension."5.07Hypotensive effects and influence on serum lipids of SQ29,852, a new angiotensin converting enzyme inhibitor, in patients with essential hypertension: a comparison with atenolol. ( Doi, Y; Kagimoto, M; Kato, K; Kawasaki, K; Koga, S; Sakai, K; Sakaue, A; Sasaki, J; Takada, K; Takii, M, 1993)
"Aortic stiffness and left ventricular hypertrophy (LVH) are predictors of mortality in hemodialysis (HD) patients."2.71Inflammation, arteriosclerosis, and cardiovascular therapy in hemodialysis patients. ( Adda, H; Guerin, AP; London, GM; Marchais, SJ; Metivier, F; Pannier, B, 2003)
" Conclusively, nipradilol, beta-blocker with nitric oxide-releasing action, in contrast to the other beta-blockers and nitric oxide donors, showed a successful anti-atherosclerotic effect through the restoration of nitric oxide bioavailability and possible interaction with oxygen radicals."1.31Anti-atherosclerotic effect of beta-blocker with nitric oxide-releasing action on the severe atherosclerosis. ( Hayashi, T; Iguchi, A; Kano, H; Matsui-Hirai, H; Sumi, D; Thakur, NK; Tsunekawa, T, 2002)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's6 (28.57)18.2507
2000's11 (52.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ariff, B1
Stanton, A1
Barratt, D1
Augst, A1
Glor, F1
Poulter, N1
Sever, P1
Xu, Y1
Hughes, A1
Thom, SA1
Bossi, M1
Tiberti, G1
London, GM1
Marchais, SJ1
Guerin, AP1
Metivier, F1
Adda, H1
Pannier, B1
Torella, F1
de Cossart, L1
Dimitri, SK1
Edwards, PR1
Giannattasio, C1
Failla, M1
Hennig, M3
Hollweck, R1
Laurent, S1
Mallion, JM1
Reid, J2
Safar, M3
Bond, G2
Zanchetti, A3
Mancia, G3
Fossum, E1
Olsen, MH1
Høieggen, A1
Wachtell, K1
Reims, HM1
Kjeldsen, SE1
Ibsen, H1
Wan, Y1
Julius, S1
Vidt, DG1
Dal Palú, C2
Hansson, L2
Magnani, B2
Neiss, A2
Rahn, KH2
Reid, JL1
Rodicio, JL1
Sasaki, J1
Koga, S1
Kato, K1
Takii, M1
Sakai, K1
Kawasaki, K1
Kagimoto, M1
Doi, Y1
Takada, K1
Sakaue, A1
Leonetti, G1
Bond, MG3
Mercuri, M1
Seifert, T1
Zschörnig, O1
Arnhold, J1
Arnold, K1
Rodicio, J1
Eckes, L1
Ravinetto, R2
Tang, R1
Thomasson, B1
Scherz, R1
Catalini, R1
Rubba, P1
Einecke, D1
Thakur, NK1
Hayashi, T1
Sumi, D1
Kano, H1
Matsui-Hirai, H1
Tsunekawa, T1
Iguchi, A1
Komai, N1
Ohishi, M1
Morishita, R1
Moriguchi, A1
Kaibe, M1
Matsumoto, K1
Rakugi, H1
Higaki, J1
Ogihara, T1
Lee, RJ1
Dickerson, DD1
Fulmor, IE1
Goldberg, ME1
Nafstad, I1
Tollersrud, S1
Eriksen, K1
Helgeland, A1
Solberg, LA1
Bredesen, J1
Dale, O1
Brook, JG1
Marmur, A1
Berkovitch, Y1
Aviram, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Triple-Blind, Parallel Study to Investigate the Effect of Losartan Versus Atenolol on the Reduction of Morbidity and Mortality in Hypertensive Patients With Left Ventricular Hypertrophy[NCT00338260]Phase 3496 participants (Actual)Interventional1995-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for atenolol and Arteriosclerosis

ArticleYear
Advances in the medical management of renovascular hypertension.
    The Urologic clinics of North America, 1984, Volume: 11, Issue:3

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Atenolol

1984

Trials

10 trials available for atenolol and Arteriosclerosis

ArticleYear
Comparison of the effects of antihypertensive treatment with angiotensin II blockade and beta-blockade on carotid wall structure and haemodynamics: protocol and baseline demographics.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2002, Volume: 3, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin II; Antihypertensive Agents

2002
Inflammation, arteriosclerosis, and cardiovascular therapy in hemodialysis patients.
    Kidney international. Supplement, 2003, Issue:84

    Topics: Adult; Antihypertensive Agents; Aortic Diseases; Arteriosclerosis; Atenolol; Blood Pressure; C-React

2003
Different relation between 24-h blood pressure and distensibility at different peripheral arteries. Data from the European Lacidipine Study on Atherosclerosis (ELSA).
    Journal of hypertension, 2005, Volume: 23, Issue:3

    Topics: Antihypertensive Agents; Arteriosclerosis; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambu

2005
Long-term effects of a losartan- compared with an atenolol-based treatment regimen on carotid artery plaque development in hypertensive patients with left ventricular hypertrophy: ICARUS, a LIFE substudy.
    Journal of clinical hypertension (Greenwich, Conn.), 2006, Volume: 8, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Arteriosclerosis; Atenol

2006
The E.L.S.A. trial: protocol of a randomized trial to explore the differential effect of antihypertensive drugs on atherosclerosis in hypertension.
    Journal of cardiovascular pharmacology, 1994, Volume: 23 Suppl 5

    Topics: Aged; Antihypertensive Agents; Arteriosclerosis; Atenolol; Dihydropyridines; Double-Blind Method; Hu

1994
Hypotensive effects and influence on serum lipids of SQ29,852, a new angiotensin converting enzyme inhibitor, in patients with essential hypertension: a comparison with atenolol.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Apolipoproteins; Arteri

1993
[The preliminary clinical evidence from the ELSA study. The European Lacidipine Study on Atherosclerosis].
    Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna, 1995, Volume: 10 Suppl

    Topics: Aged; Antihypertensive Agents; Arteriosclerosis; Atenolol; Calcium Channel Blockers; Carotid Artery

1995
Potential modification of plaque behavior through the European lacidipine study on atherosclerosis.
    Journal of cardiovascular pharmacology, 1995, Volume: 25 Suppl 3

    Topics: Adrenergic beta-Antagonists; Arteriosclerosis; Atenolol; Blood Pressure Monitoring, Ambulatory; Calc

1995
Risk factors associated with alterations in carotid intima-media thickness in hypertension: baseline data from the European Lacidipine Study on Atherosclerosis.
    Journal of hypertension, 1998, Volume: 16, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Arteriosclerosis; Atenolol; Blood Pressure; Calcium Channel Block

1998
Baseline reproducibility of B-mode ultrasonic measurement of carotid artery intima-media thickness: the European Lacidipine Study on Atherosclerosis (ELSA).
    Journal of hypertension, 2000, Volume: 18, Issue:2

    Topics: Adrenergic beta-Antagonists; Arteriosclerosis; Atenolol; Calcium Channel Blockers; Carotid Arteries;

2000

Other Studies

10 other studies available for atenolol and Arteriosclerosis

ArticleYear
[Ischemic heart disease in patients with arteriopathies].
    Minerva cardioangiologica, 2002, Volume: 50, Issue:5 Suppl 1

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Antihypertensive Agents; Arterioscle

2002
Routine beta-blockade in vascular surgery.
    Cardiovascular surgery (London, England), 2003, Volume: 11, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Amputation, Surgical; Analysis of Variance; Arteriosclerosis; Ate

2003
Beta-blockers inhibit the modification of low-density lipoproteins by sodium hypochlorite in vitro.
    Chemistry and physics of lipids, 1997, Jan-17, Volume: 85, Issue:1

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Anti-Inflammatory Agents, Non-Steroidal; Arteri

1997
[ELSA Studies studies progression of atherosclerosis. Calcium antagonist arrests the process more than a beta-blocker].
    MMW Fortschritte der Medizin, 2001, Jul-05, Volume: 143, Issue:26-27

    Topics: Adrenergic beta-Antagonists; Arteriosclerosis; Atenolol; Calcium Channel Blockers; Dihydropyridines;

2001
[Calcium antagonists lower not only blood pressure. Arteriosclerosis is braked too].
    MMW Fortschritte der Medizin, 2001, Nov-15, Volume: 143, Issue:46

    Topics: Aged; Antihypertensive Agents; Arteriosclerosis; Atenolol; Calcium Channel Blockers; Carotid Stenosi

2001
Anti-atherosclerotic effect of beta-blocker with nitric oxide-releasing action on the severe atherosclerosis.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Arteriosclerosis; Atenolol; Blood Pressure; C

2002
Serum hepatocyte growth factor concentration is correlated with the forearm vasodilator response in hypertensive patients.
    American journal of hypertension, 2002, Volume: 15, Issue:6

    Topics: Antihypertensive Agents; Arteriosclerosis; Atenolol; Blood Pressure; Cilazapril; Endothelium, Vascul

2002
Direct myocardial depressant effects of several beta-adrenergic blocking agents in the unanesthetized atherosclerotic rabbit.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:2

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arteriosclerosis; Atenolol; Blood Pressure; Depres

1978
The influence of atenolol and prazosin on serum lipids and atherosclerosis in minipigs fed a hyperlipidemic diet.
    General pharmacology, 1988, Volume: 19, Issue:5

    Topics: Animals; Arteriosclerosis; Atenolol; Body Weight; Cholesterol, Dietary; Diet; Female; gamma-Glutamyl

1988
Platelet adhesion in hyperlipidemic and hypertensive patients.
    Haemostasis, 1985, Volume: 15, Issue:6

    Topics: Adult; Arteriosclerosis; Atenolol; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinem

1985