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atenolol and Alloxan Diabetes

atenolol has been researched along with Alloxan Diabetes in 16 studies

Atenolol: A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
atenolol : An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.

Research Excerpts

ExcerptRelevanceReference
"To investigate the involvement of adrenergic mechanisms in the development of obesity, hyperglycaemia and hyperinsulinaemia in Aston ob/ob mice, the sympathomimetic agent ephedrine (12 mg/kg/day) and the predominantly beta 1-adrenergic antagonist atenolol (12 mg/kg/day) were administered alone and in combination to weanling ob/ob mice for 40 days."7.67Effects of ephedrine and atenolol on the development of obesity and diabetes in ob/ob mice. ( Bailey, CJ; Flatt, PR; Thornburn, CC, 1986)
"To determine whether diabetes leads to retinal neuronal dysfunction in hypertensive transgenic (mRen-2)27 rats (Ren-2), and whether the effect can be prevented by treatment of hypertension with either the angiotensin-1 receptor blocker (AT1-RB) valsartan or the beta1-adrenergic receptor antagonist atenolol."3.74Retinal dysfunction in diabetic ren-2 rats is ameliorated by treatment with valsartan but not atenolol. ( Fletcher, EL; Phipps, JA; Wilkinson-Berka, JL, 2007)
"Blockade of the renin-angiotensin system but not antihypertensive therapy with atenolol reduces vascular pathology in diabetic Ren-2 retina, suggesting that angiotensin II is a causative factor and therapeutic target in diabetic retinopathy."3.74Valsartan but not atenolol improves vascular pathology in diabetic Ren-2 rat retina. ( Jaworski, K; Ninkovic, S; Tan, G; Wilkinson-Berka, JL, 2007)
"To investigate the involvement of adrenergic mechanisms in the development of obesity, hyperglycaemia and hyperinsulinaemia in Aston ob/ob mice, the sympathomimetic agent ephedrine (12 mg/kg/day) and the predominantly beta 1-adrenergic antagonist atenolol (12 mg/kg/day) were administered alone and in combination to weanling ob/ob mice for 40 days."3.67Effects of ephedrine and atenolol on the development of obesity and diabetes in ob/ob mice. ( Bailey, CJ; Flatt, PR; Thornburn, CC, 1986)
"Metoprolol treatment produced a slight but significant reduction in serum glucose levels with elevation in serum insulin levels, while atenolol produced a slight increase in glucose levels but no effect on insulin levels."1.34Comparative evaluation of atenolol and metoprolol on cardiovascular complications associated with streptozotocin-induced diabetic rats. ( Bhadada, SV; Goyal, RK, 2007)
"Propranolol was found to exhibit a hypolipidemic effect in diabetic rats when administered alone or in combination with glibenclamide."1.29Studies on the glycemic and lipidemic effect of atenolol and propranolol in normal and diabetic rats. ( el Batran, S; Gaafar, K; Salama, S, 1994)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's3 (18.75)18.2507
2000's5 (31.25)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cook, RF1
Bussey, CT1
Mellor, KM1
Cragg, PA1
Lamberts, RR1
Patel, BM1
Bhadada, SV2
Angulo, J1
Wright, HM1
Cuevas, P1
González-Corrochano, R1
Fernández, A1
Cuevas, B1
La Fuente, JM1
Gupta, S1
Sáenz de Tejada, I1
Mabe, AM1
Hoover, DB1
Zhang, JZ1
Gao, L1
Widness, M1
Xi, X1
Kern, TS1
Phipps, JA1
Wilkinson-Berka, JL2
Fletcher, EL1
Tan, G1
Jaworski, K1
Ninkovic, S1
Goyal, RK2
Gaafar, K1
Salama, S1
el Batran, S1
Bangaru, RA1
Lakkad, NB1
Rao, MV1
Mitani, S1
Okumura, K1
Matsui, H1
Toki, Y1
Hashimoto, H1
Ito, T1
Hayakawa, T1
Furman, BL2
Tayo, FM2
Mehvar, R1
Nagamine, F1
Murakami, K1
Mimura, G1
Sakanashi, M1
Bailey, CJ1
Thornburn, CC1
Flatt, PR1

Other Studies

16 other studies available for atenolol and Alloxan Diabetes

ArticleYear
β
    Experimental physiology, 2017, 08-01, Volume: 102, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Diabetes Mellitus, Experimental; Dia

2017
Type 2 diabetes-induced cardiovascular complications: comparative evaluation of spironolactone, atenolol, metoprolol, ramipril and perindopril.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2014, Volume: 36, Issue:5

    Topics: Animals; Animals, Newborn; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiovascular Disease

2014
Nebivolol dilates human penile arteries and reverses erectile dysfunction in diabetic rats through enhancement of nitric oxide signaling.
    The journal of sexual medicine, 2010, Volume: 7, Issue:8

    Topics: Animals; Atenolol; Benzopyrans; Blood Glucose; Blood Pressure; Cyclic GMP; Diabetes Mellitus, Experi

2010
Remodeling of cardiac cholinergic innervation and control of heart rate in mice with streptozotocin-induced diabetes.
    Autonomic neuroscience : basic & clinical, 2011, Jul-05, Volume: 162, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Atropine; Blood Glucose; Body Weight; Data Interpret

2011
Captopril inhibits glucose accumulation in retinal cells in diabetes.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:9

    Topics: Adrenergic beta-Antagonists; Aldehyde Reductase; Angiotensin-Converting Enzyme Inhibitors; Animals;

2003
Retinal dysfunction in diabetic ren-2 rats is ameliorated by treatment with valsartan but not atenolol.
    Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:2

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically

2007
Valsartan but not atenolol improves vascular pathology in diabetic Ren-2 rat retina.
    American journal of hypertension, 2007, Volume: 20, Issue:4

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically

2007
Comparative evaluation of atenolol and metoprolol on cardiovascular complications associated with streptozotocin-induced diabetic rats.
    Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Glucose; Blood Pressure; Cardiomegaly; Cardiov

2007
Studies on the glycemic and lipidemic effect of atenolol and propranolol in normal and diabetic rats.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:4

    Topics: Animals; Atenolol; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Glyburide; Insulin;

1994
Effect of chronic treatment with atenolol and prazosin in streptozotocin induced diabetic rats.
    Indian journal of physiology and pharmacology, 1996, Volume: 40, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Diabetes Mellitus, Exp

1996
Insulin alters cardiac muscle creatine kinase activity.
    Heart and vessels, 2000, Volume: 15, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Glucose; Creatine Kinase; Data Interpretation,

2000
Effect of ICI 66082, a beta-adrenoceptor blocking drug on blood glucose in the rat.
    European journal of pharmacology, 1975, Volume: 31, Issue:1

    Topics: Adipose Tissue; Animals; Atenolol; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glyburid

1975
Effect of experimental diabetes mellitus on the pharmacokinetics of atenolol enantiomers in rats.
    Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:3

    Topics: Animals; Atenolol; Blood Glucose; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Male; Ra

1991
Effects of beta-adrenoceptor blocking agents on isolated atrial and papillary muscles from experimentally diabetic rats.
    Japanese journal of pharmacology, 1989, Volume: 49, Issue:1

    Topics: Animals; Atenolol; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relati

1989
Effects of ephedrine and atenolol on the development of obesity and diabetes in ob/ob mice.
    General pharmacology, 1986, Volume: 17, Issue:2

    Topics: Aging; Animals; Atenolol; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Experime

1986
Proceedings: The hypoglycaemic action of ICI 66082 (4-(2-hydroxy-3-isopropyl-aminopropoxy) phenyl acetamide) in the rat.
    British journal of pharmacology, 1974, Volume: 52, Issue:1

    Topics: Acetamides; Adrenergic beta-Antagonists; Animals; Atenolol; Blood Glucose; Diabetes Mellitus, Experi

1974