Page last updated: 2024-09-02

asulacrine and Lung Neoplasms

asulacrine has been researched along with Lung Neoplasms in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199010 (76.92)18.7374
1990's3 (23.08)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atwell, GJ; Baguley, BC; Denny, WA; Rewcastle, GW1
Atwell, GJ; Baguley, BC; Denny, WA; Finlay, GJ; Rewcastle, GW; Twigden, SJ; Wilson, WR1
Baguley, BC; Grove, W; Hardy, JR; Harvey, VJ; Smith, S1
Baguley, BC; Finlay, GJ2
Baguley, BC; Evans, PC; Jurlina, JL; Kestell, P; Paxton, JW; Robertson, IG; Young, D1
Clark, GM; Elslager, EE; Lathan, B; Von Hoff, DD1
Baguley, BC; Calveley, SB; Harvey, VJ1
Baguley, BC; Finlay, GJ; Wilson, WR2
Baguley, BC; Corbett, TH; Griswold, DP; Leopold, WR; Plowman, J1
Baguley, BC; Wilson, WR1
Baguley, BC; Grimwade, CD; Kernohan, AR1

Other Studies

13 other study(ies) available for asulacrine and Lung Neoplasms

ArticleYear
Potential antitumor agents. 48. 3'-Dimethylamino derivatives of amsacrine: redox chemistry and in vivo solid tumor activity.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Amsacrine; Animals; Antineoplastic Agents; Carcinoma; Cell Line; Chemical Phenomena; Chemistry; Colonic Neoplasms; DNA; Humans; Leukemia, Experimental; Lung Neoplasms; Mice; Oxidation-Reduction; Structure-Activity Relationship

1987
Synthesis, antitumor activity, and DNA binding properties of a new derivative of amsacrine, N-5-dimethyl-9-[(2-methoxy-4-methylsulfonylamino) phenylamino]-4-acridinecarboxamide.
    Cancer research, 1984, Volume: 44, Issue:8

    Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cattle; Cell Division; Cell Line; Cell Survival; Cricetinae; DNA; Drug Evaluation, Preclinical; Humans; Indicators and Reagents; Intercalating Agents; Leukemia L1210; Leukemia P388; Lung Neoplasms; Mice; Mice, Inbred Strains; Thymus Gland

1984
Phase II study of the amsacrine analogue CI-921 (NSC 343499) in non-small cell lung cancer.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:12

    Topics: Adult; Aged; Amsacrine; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Neutropenia; Seizures

1991
Potentiation by phenylbisbenzimidazoles of cytotoxicity of anticancer drugs directed against topoisomerase II.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:5

    Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Benzimidazoles; Bisbenzimidazole; Colonic Neoplasms; Doxorubicin; Drug Synergism; Etoposide; Fluorescent Dyes; Leukemia L1210; Lung Neoplasms; Melanoma; Mice; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
Disposition of amsacrine and its analogue 9-([2-methoxy-4-[(methylsulfonyl)amino]phenyl]amino)-N,5-dimethyl-4- acridinecarboxamide (CI-921) in plasma, liver, and Lewis lung tumors in mice.
    Cancer research, 1990, Feb-01, Volume: 50, Issue:3

    Topics: Amsacrine; Animals; Antineoplastic Agents; Carcinoma; Liver; Lung Neoplasms; Male; Metabolic Clearance Rate; Mice; Solubility

1990
Selectivity of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide towards Lewis lung carcinoma and human tumour cell lines in vitro.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:2

    Topics: Acridines; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Humans; Lung Neoplasms; Mice; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
Evaluation of an amsacrine analog in a human tumor cloning system.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:4

    Topics: Amsacrine; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Drug Resistance; Humans; Lung Neoplasms; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
Effects of CI-921, an analogue of amsacrine, on advanced Lewis lung tumours in mice: relevance to clinical trials.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:2

    Topics: Amsacrine; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Flow Cytometry; Lung; Lung Neoplasms; Mice; Time Factors; Tumor Cells, Cultured

1988
Cytokinetic factors in drug resistance of Lewis lung carcinoma: comparison of cells freshly isolated from tumours with cells from exponential and plateau-phase cultures.
    British journal of cancer, 1987, Volume: 56, Issue:6

    Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Survival; Doxorubicin; Drug Resistance; Interphase; Lung Neoplasms; Mice; Mice, Inbred Strains; Mitosis; Time Factors; Tumor Cells, Cultured

1987
Experimental antitumor activity of the amsacrine analogue CI-921.
    Journal of the National Cancer Institute, 1987, Volume: 79, Issue:2

    Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Line; Colonic Neoplasms; Disease Models, Animal; Drug Evaluation, Preclinical; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains

1987
Comparison of in vivo and in vitro drug sensitivities of Lewis lung carcinoma and P388 leukaemia to analogues of amsacrine.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:6

    Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Line; Drug Evaluation, Preclinical; Female; Leukemia P388; Leukemia, Experimental; Lung Neoplasms; Mice; Neoplasm Transplantation; Tumor Stem Cell Assay

1987
Cytokinetic resistance of Lewis lung carcinoma to cyclophosphamide and the amsacrine derivative CI-921.
    Progress in clinical and biological research, 1986, Volume: 223

    Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cyclophosphamide; Drug Resistance; Lung Neoplasms; Mice; Neoplasms, Experimental; Tumor Stem Cell Assay

1986
Schedule dependence of activity of the amsacrine analogue CI-921 towards P388 leukaemia and Lewis lung carcinoma.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:11

    Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Injections, Intraperitoneal; Leukemia P388; Leukemia, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred Strains

1985